Search clinical trials for: Liver Activity

Total 27527 results

Hopital Montfort

Not yet recruiting

Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity

Liver Steatosis | MASLD | MASH
The Christie NHS Foundation Trust
University College London Hospitals; University College, London; Royal Free Hospital...

Not yet recruiting

Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar Cholangiocarcinoma (EMPHATIC)

Cholangiocarcinoma
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

A Home-based Exercise and Physical Activity Intervention After Liver Transplantation: Impact of Exercise Intensity (PHOENIX-L)

Liver Transplantation | Physical Fitness

Belgium
King Chulalongkorn Memorial Hospital
Chulalongkorn University

Not yet recruiting

The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis

Physical Activity | Cirrhosis | Sarcopenia | Heart Rate Variability | Physical Functional Performance | Lifestyle Modification | Autonomic Dysfunction | Endothelial Function | Autonomic Nervous System | Aerobic Exercises | Flow Mediated Dilation

Thailand
Azienda Ospedaliera Specializzata in Gastroenterologia...
Russo Francesco; Cozzolongo Raffaele; Shahini Endrit; Zappimbulso Marianna; Giannuzzi... and other collaborators

Recruiting

Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters. (NAFLD-POS5)

Obesity | NAFLD | IBS

Italy
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan, Spain, France
AstraZeneca
Daiichi Sankyo

Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Breast Cancer

United States, Spain, China, Italy, Australia, United Kingdom, Korea, Republic of, Vietnam, Japan, Turkey, Brazil, Taiwan, Thailand, Canada, Argentina, India, France, Singapore, Mexico, Germany, Philippines, Poland, South Africa
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Hepatocellular Carcinoma | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Biliary Tract Cancers | Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer | Head and Neck Squamous-Cell Carcinoma

United States, Israel, Japan, Puerto Rico, Korea, Republic of, Taiwan
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.

Acute on Chronic Liver Failure

India
Cedars-Sinai Medical Center

Not yet recruiting

Feasibility of Wearable Biosensors for Monitoring Daily Activity, Heart Rate, and Sleep Among Patients With Decompensated Cirrhosis

Liver Cirrhosis, Alcoholic
National Cancer Institute (NCI)

Recruiting

Durvalumab With Gemcitabine and Cisplatin for the Treatment of High Risk Resectable Liver Cancer Before Surgery

Resectable Intrahepatic Cholangiocarcinoma

United States
Academisch Ziekenhuis Maastricht

Recruiting

Perioperative Energy Expenditure in Major Liver Resection (PRO-NRG)

Liver Diseases | Cancer | Liver Neoplasms

Netherlands
Idoia Labayen
Hospital Universitario de Navarra

Recruiting

Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity

Obesity | Sarcopenia | Menopause Related Conditions | Osteoporosis Postmenopausal

Spain
AbbVie

Recruiting

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-1)

Hepatocellular Carcinoma

United States, Japan, Taiwan, Korea, Republic of, Spain, France, Italy
Boehringer Ingelheim

Recruiting

A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

Liver Cirrhosis

Germany
Pontificia Universidad Catolica de Chile

Recruiting

Prevention of NAFLD and CVD Through Lifestyle Intervention (MAUCO+)

Non-Alcoholic Fatty Liver Disease | Gallstone Disease

Chile
UNICANCER
Cancer Research UK; National Cancer Institute, France; Servier; Pierre Fabre Medicament and other collaborators

Recruiting

Personalized Medicine for Advanced Biliary Cancer Patients (SAFIR-ABC10)

Biliary Tract Neoplasms

France, Belgium, United Kingdom
Genmab
AbbVie

Recruiting

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (EPCORE DLBCL-2)

Diffuse Large B-Cell Lymphoma

Korea, Republic of, Spain, Japan, Israel, Australia, Poland, Netherlands, Sweden, Greece, Taiwan, Italy, Denmark, Switzerland, France, Bulgaria, Hungary, Austria, New Zealand, Czechia, Croatia, Belgium, Brazil, China, United States, Canada and more
Merck Sharp & Dohme LLC

Recruiting

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008)

Hodgkin Lymphoma

Australia, Israel, Korea, Republic of, Spain, Poland, Sweden, United Kingdom, Turkey, China, United States, Brazil, Germany, Belgium, France, Switzerland, Canada, Czechia, Chile, Argentina
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice (PROFUNDUS)

Ulcerative Colitis

Germany, Russian Federation, United Arab Emirates, United Kingdom, Australia, Ireland, Argentina, Canada, Kuwait, Israel, Portugal, Czechia, France, Greece, Italy
University of Bari

Not yet recruiting

Beneficial Effects of Dietary and Lifestyle Change in Overweight and Obese Subjects (Healthy-MET)

Cardiovascular Diseases | Metabolic Syndrome | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

Italy
University of Roma La Sapienza
Alexion Pharmaceuticals

Recruiting

Lysosomal Acid Lipase Activity in Nonalcoholic Fatty Liver Disease (NAFLD LAL)

Non-Alcoholic Fatty Liver Disease

Italy
Genmab
AbbVie

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma (EPCORE FL-1)

Follicular Lymphoma (FL)

Austria, Greece, Israel, Korea, Republic of, Spain, Hungary, Sweden, Switzerland, France, Poland, Taiwan, Australia, Denmark, New Zealand, Turkey, Italy, Netherlands, Belgium, Canada, South Africa, Czechia, Brazil, Germany, Argentina, United... and more
University of L'Aquila

Recruiting

Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease) (NAFLD)

NAFLD- Non Alcoholic Fatty Liver Disease

Italy
AbbVie

Recruiting

A Study to Assess the Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma Receiving Oral ABBV-453 Tablets

Relapsed/Refractory Multiple Myeloma

United States, Australia, Israel, United Kingdom
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust

Recruiting

Breaking up Sedentary Time in Rheumatoid Arthritis

Rheumatoid Arthritis | Endothelial Dysfunction | Sedentary Behavior

United Kingdom
Quell Therapeutics Limited

Recruiting

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients (LIBERATE)

Liver Diseases | Liver Failure | Rejection; Transplant, Liver

Belgium, United Kingdom, Spain
Boehringer Ingelheim

Not yet recruiting

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

Obesity
Hacettepe University

Recruiting

The Effect of Aerobic and Resistant Exercise Training in Patients With Non-Alcoholic Steatohepatitis

Non-Alcoholic Steatohepatitis

Turkey
Karolinska University Hospital
Karolinska Institutet

Recruiting

Instructed Home-based Physical Exercise for Patients With Liver Cirrhosis (INSPEL)

Liver Cirrhosis

Sweden
Liverpool John Moores University
Oxford University Hospitals NHS Trust

Recruiting

mHealth Biometrics for Young People With Diabetes (MOTIVATE-HfH)

Diabetes

United Kingdom
Liverpool John Moores University
Alder Hey Children's NHS Foundation Trust

Recruiting

mHealth Biometrics for Young People With Obesity (MOTIVATE- LOOP) (MOTIVATE-L)

Obesity, Adolescent

United Kingdom
Centre Hospitalier Universitaire de Nice

Recruiting

Interest of APA in Fatty Liver Disease Evaluation of Efficacy and Adherence to an Adapted Physical Activity (APA) Program in Patients With Metabolic Fatty Liver Disease (STEATO-APA)

Non-Alcoholic Fatty Liver Disease (NAFLD

France
Yale University
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

NAFLD

United States
Robert Jones and Agnes Hunt Orthopaedic and District...
University of Liverpool; University of Aberdeen; Bournemouth University; Keele...

Recruiting

Shoulder Instability in Children: Muscle Activity and Movement

Shoulder Injuries | Pediatric ALL | Musculoskeletal Injury | Instability, Joint | Dislocation, Shoulder

United Kingdom
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Urinary Bladder Neoplasms

United States, Australia, Czechia, Estonia, France, Guatemala, Hungary, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Poland, Portugal, Puerto Rico, Romania, Spain, Taiwan, Turkey, Ukraine, United Kingdom, Denmark, ... and more
Abion Inc
Novotech (Australia) Pty Limited

Recruiting

To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation

Advanced Solid Tumors

Australia, Korea, Republic of
Ottawa Hospital Research Institute

Recruiting

Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity

Hepatitis B, Chronic

Canada
Bayer
Ultragenix pharmaceutical

Active, not recruiting

Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle".

Hemophilia A

Netherlands, United States, Germany, United Kingdom, France, Bulgaria
Cairo University

Active, not recruiting

Efficacy and Safety of Dapagliflozin in Patients With Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

Egypt
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy and Safety of NIS793 in Combination With Standard of Care (SOC) Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) - daNIS-2

Metastatic Pancreatic Ductal Adenocarcinoma

United States, China, Hungary, Taiwan, Belgium, Germany, Spain, Italy, Czechia, France, Japan, Switzerland, Australia, Israel, Korea, Republic of, Canada, Russian Federation, Slovakia, United Kingdom, Turkey, Sweden, Greece, Finland, ... and more
University of Birmingham
University of Oslo; The Leeds Teaching Hospitals NHS Trust; University of Padova and other collaborators

Active, not recruiting

Paediatric Hepatic International Tumour Trial (PHITT)

Carcinoma, Hepatocellular | Hepatoblastoma

United Kingdom, France, Austria, Israel, Spain, Belgium, Czechia, Finland, Germany, Ireland, Netherlands, Norway, Poland, Switzerland
University of Bari
Prof. Maria Grano

Completed

Sarcopenic Obesity in Liver Transplanted Patients (OSaLT)

Sarcopenic Obesity

Italy
BeiGene

Completed

Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma

Hepatocellular Carcinoma | Unresectable Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma

China
Hoffmann-La Roche

Active, not recruiting

A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)

Non-Small-Cell Lung

United States, Korea, Republic of, United Kingdom, Australia, France, Italy, Spain, Japan, Brazil, China, Germany, Poland, Thailand, Israel, Switzerland, Taiwan, Austria, Russian Federation, Ukraine, Hungary, Serbia, Slovenia, South... and more
AbbVie

Active, not recruiting

Study to Evaluate Adverse Events and Change in Disease Activity in Adult and Adolescent Participants With Acute Hepatitis C Virus (HCV) Infection on Treatment With Oral Tablets of Glecaprevir (GLE)/Pibrentasvir (PIB)

Hepatitis C Virus (HCV)

United States, Australia, Austria, Canada, France, Germany, Italy, Spain
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Hepatoblastoma | Fibrolamellar Carcinoma | Childhood Hepatocellular Carcinoma | Childhood Malignant Liver Neoplasm | Hepatocellular Malignant Neoplasm, Not Otherwise Specified

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
The University of Texas Medical Branch, Galveston

Active, not recruiting

Acute Porphyria Biomarkers for Disease Activity

Hereditary Coproporphyria | Acute Intermittent Porphyria | Variegate Porphyria

United States

Search clinical trials for: Liver Activity

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