Search clinical trials for: Metastatic colorectal cancer, Panitumumab, mFOLFOX6, Bevacizumab

Total 23314 results

Weijing Sun, MD, FACP

Withdrawn

A Study of Perioperative mFOLFOX6 Plus Pembrolizumab in Patients With Potentially Resectable Adenocarcinoma of the Gastroesophageal Junction (GEJ) and Stomach

Adenocarcinoma | Stomach Cancer

United States
Takeda

Active, not recruiting

An Exploratory Study of Treatment Sensitivity and Prognostic Factors in a Efficacy and Safety Study of mFOLFOX6 + Bevacizumab Versus mFOLFOX6 + Panitumumab Therapy in Patients With Chemotherapy-naïve Unresectable Advanced or Recurrent Colorectal Cancer

Colorectal Cancer

Japan
Takeda

Completed

Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC (PARADIGM)

Colorectal Cancer

Japan
Fudan University

Recruiting

Fruquintinib With mFOLFOX6/FOLFIRI as First-Line Therapy for Conversion Surgery in mCRC

Colorectal Cancer

China
Sun Yat-sen University

Recruiting

Neoadjuvant Treatment With mFOLFOXIRI Plus Cadonilimab (AK104) Versus mFOLFOX6 in Locally Advanced Colorectal Cancer (OPTICAL-2)

Colorectal Cancer

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis (CANWATCH)

Colorectal Cancer | Adjuvant Chemotherapy

China
Xu jianmin

Unknown

Cetuximab in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer

Neoplasm Metastasis | Liver Neoplasms | Colorectal Neoplasms

China
Amgen

Completed

Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Colon Cancer

United States
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
Takeda

Completed

Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma (SAPPHIRE)

Colorectal Carcinoma

Japan
Martin-Luther-Universität Halle-Wittenberg
GALMED GmbH

Completed

TRICC-C (AIO-KRK-0111): BIBF 1120 Versus Placebo in Patients Receiving Oxaliplatin Plus Fluorouracil and Leucovorin (mFOLFOX6) for Advanced, Chemorefractory Metastatic Colorectal Cancer (mCRC) (AIO-KRK-0111)

Colorectal Cancer

Germany
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

mFOLFOX6+Bevacizumab+PD-1 Monoclonal Antibody in Local Advanced MSS CRC (BASKETⅡ)

Colorectal Cancer | Immunotherapy

China
Clinical Research Support Center Kyush

Unknown

RP II Study of SOX vs mFOLFOX6 in Patients With Resectable Rectal Cancer (KSCC1301).

Rectal Cancer

Japan
Novartis Pharmaceuticals

Terminated

PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer

Metastatic Colorectal Cancer

United Kingdom
NRG Oncology
National Cancer Institute (NCI); Natera, Inc.

Recruiting

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

Stage III Colon Cancer

United States, Canada
Fudan University

Not yet recruiting

Cetuximab+mFOLFOX6 VS. mFOLFOX6 Alone in RAS/BRAF Wild Type Patients With High-Risk Resectable CRLM

Colorectal Cancer | Liver Metastases

China
AVEO Pharmaceuticals, Inc.

Completed

A Study Combining mFOLFOX6 With Tivozanib or Bevacizumab in Patients With Metastatic Colorectal Cancer as First Line Therapy

Colorectal Cancer

United States, Hungary, United Kingdom, Australia, Spain, Netherlands, Italy, Czech Republic, Canada, Austria, Belgium, Finland
AbbVie (prior sponsor, Abbott)
Genentech, Inc.

Completed

Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

Advanced Colorectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States, Australia, Belgium, Brazil, Canada, Czech Republic, Greece, Korea, Republic of, New Zealand, Poland, Portugal, Romania, Russian Federation, Spain
Fujian Cancer Hospital

Not yet recruiting

Second-line Surufatinib Combined With Chemotherapy in Advanced CRC

Advanced Colorectal Cancer
Fudan University

Not yet recruiting

The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Fujian Medical University Union Hospital

Recruiting

Short-course Radiotherapy (5×6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer

Rectal Cancer | Radiation Oncology

China
Tianjin Medical University Cancer Institute and...

Unknown

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC

Colorectal Cancer

China
Patrick Boland
Bristol-Myers Squibb; Hoosier Cancer Research Network; Bavarian Nordic

Active, not recruiting

A Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC

Metastatic Colorectal Cancer

United States
Amgen

Completed

PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors

Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Colon Cancer

United States, Belgium, Canada, Italy, Germany, Spain
Henan Cancer Hospital

Not yet recruiting

PD1 Antibody Combined With mFOLFOX6 Neoadjuvant Therapy for Advanced Resectable Metastatic Colon Cancer

Metastatic Colon Cancer
Qilu Pharmaceutical Co., Ltd.

Recruiting

QL1203 In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy and Safety

Metastatic Colorectal Cancer

China
Zhou Fuxiang
Xiangya Hospital of Central South University; Henan Cancer Hospital; Hubei Cancer... and other collaborators

Recruiting

Fruquintinib Combined With mFOLFOX6/FOLFIRI in First-line Treatment for Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Fudan University

Recruiting

The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

Surgery | Metastatic Colon Cancer

China
Baruch Brenner
Bristol-Myers Squibb

Recruiting

Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients

Rectal Cancer

Israel
Tianjin Medical University Cancer Institute and...

Unknown

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in Advanced Gastric Cancer

Gastric Cancer

China
Centre Hospitalier Universitaire Dijon

Recruiting

CIRCULATING TUMOR DNA BASED DECISION FOR ADJUVANT TREATMENT IN COLON CANCER STAGE II (CIRCULATE)

Patients With Resected Stage II Colon Cancer

France
Ning Jin

Active, not recruiting

Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
AIO-Studien-gGmbH
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer (MEFOX)

Chemo-refractory Colorectal Carcinoma

Germany
Shanghai Henlius Biotech

Not yet recruiting

Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07+HLX10 +mFOLFOX6 or HLX07 Monotherapy in Patients With mCRC

CRC
Seoul National University Bundang Hospital
Boryung Pharmaceutical Co., Ltd; B. Braun Korea Co., Ltd.

Completed

Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6 (IPLUS)

Peritoneal Carcinomatosis | Gastric Cancer Stage IV | Intraperitoneal Paclitaxel | mFOLFOX6

Korea, Republic of
UNICANCER
Canadian Cancer Trials Group; GONO GROUP

Active, not recruiting

IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting (IROCAS)

Colon Cancer (High-risk Stage III: pT4N1 or pT1 to 4 N2)

France, Canada
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

mFOLFOX6 Combined With Dalpiciclib in Patients With Metastatic Colorectal Cancer (FIND)

Advanced/Metastatic Colorectal Cancer

China
UNC Lineberger Comprehensive Cancer Center

Completed

BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

Metastatic Colorectal Cancer | Advanced Solid Tumors | Metastatic Pancreatic Cancer

United States
Takeda

Recruiting

An Additional Analysis of Data From the PARADIGM Exploratory Study (NCT02394834) in Patients With Advanced/Recurrent Colorectal Cancer

Colorectal Cancer

Japan
Fudan University

Unknown

Study of Cetuximab in Combination With mFOLFOX-6 (Oxaliplatin, Leucovorin, 5-FU) to Treat Colorectal Liver Metastatic Cancer Patients (CLIME)

Colorectal Cancer | Liver Metastases

China
Henan Cancer Hospital

Completed

Continuing Cetuximab Plus Chemotherapy After First Progression in Wild-type KRAS, NRAS and BRAF V600E Metastatic Colorectal Cancer

Wild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
Yanhong Deng

Not yet recruiting

Adjuvant mFOLFOXIRI vs. mFOLFOX6 in MRD Positive Stage II-III Colorectal Cancer (AFFORD) (AFFORD)

Colorectal Cancer
Zhejiang Cancer Hospital

Unknown

Endostar Combined With mFOLFOX6 for First-line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Hokkaido Gastrointestinal Cancer Study Group
Hokkaido University Hospital

Suspended

IRIS Followed by mFOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer

Metastatic Colorectal Cancer

Japan
West China Hospital
First Affiliated Hospital of Chongqing Medical University

Recruiting

First-line mCapOX+Cetuximab vs. mFOLFOX6+Cetuximab for Metastatic Left-sided CRC With Wild-type RAS/BRAF Genes (CAPCET)

Colo-rectal Cancer | Capecitabine | Cetuximab

China
Sirtex Medical

Completed

FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer (SIRFLOX)

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma

United States, Israel, Australia, Belgium, New Zealand, Spain, Germany, Switzerland, Italy, France, Poland
Myriad Genetic Laboratories, Inc.

Terminated

Study Comparing Optimized 5-FU Dosing and Standard Dosing in Metastatic Colorectal Cancer Patients Treated With mFOLFOX6 (PROFUSE)

Colorectal Cancer, Metastatic

United States
Accelerated Community Oncology Research Network
Bayer

Terminated

A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

United States
Fudan University

Recruiting

mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases

Liver Metastases | Colorectal Carcinoma

China
Fudan University

Unknown

Recombinant Human Endostatin in Combination With mFOLFOX6 in Patients With Metastatic Colorectal Cancer

Colorectal Neoplasm

China

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