Search clinical trials for: Mitochondrial oxidative phosphorylation

Total 1987 results

Khondrion BV
Julius Clinical; ProPharma Group; Europees Fonds voor Regionale Ontwikkeling... and other collaborators

Recruiting

The KHENERGYC Study

Mitochondrial Diseases | MELAS | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Subacute Necrotizing Encephalomyelopathy

Netherlands
Hong Kong Children's Hospital
The University of Hong Kong

Recruiting

Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases

Mitochondrial Diseases

Hong Kong
University Hospital, Strasbourg, France

Recruiting

Metabolic Study of Cockayne Syndrome (METABO-CS)

Cockayne Syndrome

France
National Human Genome Research Institute (NHGRI)

Recruiting

The NIH MINI Study: Metabolism, Infection, and Immunity in Inborn Errors of Metabolism

Mitochondrial Disorders | Leigh Disease | Oxidative Phosphorylation Deficiencies | Electron Transport Chain Disorders, Mitochondrial

United States
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
University Hospital Center of Martinique

Terminated

Mitochondrial Function in Transthyretin Amyloidosis (MIT-Amylose)

Cardiac Amyloidosis

Martinique
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Tissue Sample Study for Mitochondrial Disorders

Mitochondrial Disease | Mitochondrial Disorders | Melas | Kearns Sayer | NARP | MNGIE | LHON | Mitochondrial Depletion Syndrome | Leigh's Disease

United States
Khondrion BV
Julius Clinical

Completed

The KHENERGYZE Study

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Encephalomyopathies | MIDD

Netherlands, Denmark, Germany, United Kingdom
National Human Genome Research Institute (NHGRI)

Completed

EPI-743 for Metabolism or Mitochondrial Disorders

Mitochondrial Disease | Myopathy | Neurology

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome

Cancer | Muscle Weakness | Skin Fibroblasts

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

Heart Failure

United States
Khondrion BV
Radboud University Medical Center

Completed

The KHENERGY Study (KHENERGY)

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS | Mitochondrial Encephalomyopathies | MIDD

Netherlands
Texas Tech University

Not yet recruiting

Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm

Preterm Birth
University School of Physical Education, Krakow...
Ministry of Education and Science,Poland

Recruiting

The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males

Hypoxia, Altitude

Poland
University Hospital, Clermont-Ferrand

Recruiting

Evaluation of Muscle Oxidative Capacity Relationship With Muscular Endurance, Fatigue (Multiple Sclerosis). (OXYSEP)

Multiple Sclerosis

France
Istituto Auxologico Italiano

Recruiting

Oxidative Stress and Mitochondrial TERT in Papillary Thyroid Cancer. (TEMPEST)

Papillary Thyroid Cancer

Italy
University Hospital, Angers
Fondation de l'Avenir

Recruiting

MITAORTA - Role of Mitochondrial Dynamic in Aneurysm and Dissection of Ascending Thoracic Aorta (MITAORTA)

Aortic Aneurysm and Dissection

France
Imperial College London
British Heart Foundation

Recruiting

Examining the Effects of Mitochondrial Oxidative Stress in DCM (MitoDCM)

Dilated Cardiomyopathy

United Kingdom
Patrizia D'Amelio

Not yet recruiting

Maintaining Immune and Mitochondrial Functions in Old Adults With SAfe Nutrition. (MIMOSA)

Malnutrition | Sarcopenia

Switzerland
Hopital Foch
National Cancer Institute, France

Not yet recruiting

Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide (OPTIMUM)

Glioblastoma, IDH-wildtype

France, Italy
Emergent BioSolutions
Department of Health and Human Services

Completed

Botulism Antitoxin Effects on Paralysis Induced by Botulinum Neurotoxins in the EDB Muscle

Healthy Volunteers

United States
PTC Therapeutics

Completed

A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy (MIT-E)

Mitochondrial Diseases | Drug Resistant Epilepsy | Leigh Disease | Leigh Syndrome | Mitochondrial Encephalopathy (MELAS) | Pontocerebellar Hypoplasia Type 6 (PCH6) | Alpers Disease | Alpers Syndrome

United States, Spain, United Kingdom, Canada, France, Italy, Poland, Sweden, Japan
Celia Bañuls
Instituto de Salud Carlos III

Active, not recruiting

Gut Microbiota, Mitochondrial Function and Metabolic Health in Obesity

Obesity Adult Onset

Spain
Reata, a wholly owned subsidiary of Biogen
AbbVie; Friedreich's Ataxia Research Alliance

Active, not recruiting

RTA 408 Capsules in Patients With Friedreich's Ataxia - MOXIe

Friedreich Ataxia

United States, Australia, Austria, Italy, United Kingdom
Vanderbilt University
National Institute of General Medical Sciences (NIGMS)

Completed

Risk of Oxygen During Cardiac Surgery Trial (ROCS)

Cardiac Surgery

United States
University of Nebraska
National Institute on Aging (NIA); American Heart Association

Completed

Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies

Peripheral Arterial Disease

United States
Louisiana State University and A&M College
Delfi, Inc.

Completed

BFR and Muscle Mitochondrial Oxidative Capacity

Hypertrophy | Strength | Mitochondria

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Oxidative Phosphorylation Inhibitor IACS-010759 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
Ball State University

Completed

Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging

Aging | Endothelial Dysfunction | Arterial Stiffness | Cardiovascular Function

United States
Baylor College of Medicine

Active, not recruiting

Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19

Covid19

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Liverpool John Moores University; Australian Catholic University

Completed

Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome (HIT-FAT)

Polycystic Ovary Syndrome

Australia, Norway
Comenius University
GYN-FIV

Active, not recruiting

Effect of COVID-19 on Platelet Mitochondrial Bioenergetic, Antioxidants and Oxidative Stress in Infertile Men. (COVInfertility)

COVID-19 | Infertility, Male

Slovakia
University of Guadalajara
Instituto Mexicano del Seguro Social

Completed

Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy

Diabetic Retinopathy

Mexico
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Oxidative Capacity and Exercise Tolerance in Ambulatory SMA

Spinal Muscular Atrophy Type 3 | Mitochondrial Myopathy

United States
Ain Shams University

Completed

A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients

Antioxidative Stress | End Stage Renal Disease on Dialysis

Egypt
Comenius University
Sanatórium of Dr. Guhr, n.o.; Kaneka Pharma Europe N.V.

Completed

Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome (SpaCOVID)

COVID-19 Respiratory Infection

Slovakia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

IACS-010759 in Advanced Cancers

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
Tungs' Taichung Metroharbour Hospital

Completed

Association of Uremic Sarcopenia and Mitochondrial Copy Number and Its Clinical Correlates

Sarcopenia | Mitochondrial DNA

Taiwan
Fundación para el Fomento de la Investigación Sanitaria...

Completed

Involvement of Reticulum Endoplasmic Stress in the Physiopathology of Polycystic Ovary Syndrome (PI12/1984)

Polycystic Ovary Syndrome

Spain
Hospices Civils de Lyon

Completed

Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients (DIAXO)

Type 2 Diabetes Mellitus

France
University of Delaware

Unknown

Mitochondrial Oxidative Stress and Vascular Health in Chronic Kidney Disease

Chronic Kidney Disease

United States
University of Copenhagen

Completed

The Production of Reactive Oxygen Species in Response to Glutathione Supplementation and Acute Exercise (DIMITOS)

Type 2 Diabetes | Oxidative Stress | Mitochondrial Reactive Oxygen Species Production

Denmark
University of Chile
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile

Terminated

Beneficial Effects of Exercise and Healthy Diets on Muscle and Adipose Tissue

Metabolic Syndrome

Chile
National Institute of Nursing Research (NINR)

Completed

Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy

Cancer | Fatigue

United States
Weill Medical College of Cornell University

Completed

Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers

Parkinson Disease
Duke University

Terminated

Hyperbaric VO2max Study

Exercise Training

United States
Beth Israel Deaconess Medical Center

Completed

Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS

Hypercholesterolemia | Myopathy | HMG COA Reductase Inhibitor Adverse Reaction

United States
University Hospital, Lille

Completed

Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin (OXYDIAB)

Type 1 Diabetes

France
Corporal Michael J. Crescenz VA Medical Center

Completed

Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity

Heart Failure With Normal Ejection Fraction

United States
Maimónides Biomedical Research Institute of Córdoba

Unknown

Beneficial Effects of Coenzyme Q10 Treatment on the Mitochondrial Dysfunction and Oxidative Stress Associated to Atherothrombosis Developement in Antiphospholipidid Syndrome Patients (coenzyme Q10)

Coenzyme Q10 on Athero-thrombosis in APS Patients

Spain

Search clinical trials for: Mitochondrial oxidative phosphorylation

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