Search clinical trials for: Moderate to severe pain following bunionectomy surgery

Total 476398 results

Abbott

Completed

A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery

Pain

United States
NEMA Research, Inc.

Recruiting

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
Teva Branded Pharmaceutical Products R&D, Inc.
Syneos Health

Completed

Study to Evaluate the Analgesic Efficacy and Safety of Hydrocodone Bitartrate/Acetaminophen Immediate-Release Tablets in Participants With Moderate to Severe Pain Following Bunionectomy

Pain

United States
Mallinckrodt

Completed

A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients

Acute Pain

United States
Novartis Pharmaceuticals

Completed

Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib

Pain

United States
The Fourth Affiliated Hospital of Zhejiang University...

Not yet recruiting

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

Postoperative Pain
The Second Affiliated Hospital of Chongqing Medical...
The First Affiliated Hospital of Zhengzhou University; ChongGang General Hospital and other collaborators

Recruiting

Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain

Postoperative Pain

China
EMS

Not yet recruiting

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (ALIV)

Moderate Pain | Severe Pain
Organon and Co
Iqvia Pty Ltd

Recruiting

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain (ELENA)

Endometriosis

United States, Hungary, Poland, France, Germany, Czechia, Belgium, Bulgaria, Italy, Latvia
Spine BioPharma, Inc
MCRA

Recruiting

Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine (MODEL)

Lumbar Degenerative Disc Disease

United States
Pharmbio Korea Co., Ltd.

Recruiting

Study of PBK_L1704 for the Treatment of Moderate to Severe Acute Pain After Bunionectomy in South Korea

Acute Pain

Korea, Republic of
AbbVie

Recruiting

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis

United States, Puerto Rico
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease (CULTIVATE)

Crohn's Disease

United States, Korea, Republic of, Netherlands, Colombia, Israel, Italy, Lebanon, Mexico, Poland, Spain, Turkey, Australia, Georgia, Czechia, Belgium, Germany, South Africa, Greece, Russian Federation, United Kingdom, Croatia, Serbia and more
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis (ELEVATE UC OLE)

Ulcerative Colitis

Poland, Japan, Georgia, Estonia, United States, Czechia, Australia, Korea, Republic of, Lithuania, Italy, Hungary, Turkey, Spain, Romania, Serbia, Germany, France, Bulgaria, Austria, Belarus, Canada, Croatia, Denmark, Israel, Latvia, Lebanon and more
Başakşehir Çam & Sakura City Hospital

Completed

The Effect of Fascia Iliaca Compartment Block (FICB) on QoR-15 Score in Partial Hip Arthroplasty Surgery (QoR-15)

Anesthesia, Local | Post Operative Pain | Fracture of Hip | QoR-15

Turkey
Luye Pharma Group Ltd.

Completed

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Abdominal Surgery

Pain, Postoperative

China
AbbVie

Completed

A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain

Endometriosis

United States, Canada, Puerto Rico
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
Universidad de Almeria
Ministerio de Economía y Competitividad, Spain; Complejo Hospitalario Torrecárdenas...

Completed

Exercise Following Bariatric Surgery for Severe/Morbid Obesity (EFIBAR) (EFIBAR)

Obesity, Morbid | Bariatric Surgery Candidate

Spain
ACADIA Pharmaceuticals Inc.

Completed

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

Acute Postoperative Pain | Bunionectomy

United States
Groupe Hospitalier Paris Saint Joseph

Completed

Impact of Moderate to Severe Pain in the Post-intervention Monitoring Room After Hemorrhoidectomy on the Length of Stay in the Outpatient Surgery Unit (HEM_DOULEUR)

Surgery | Hemorrhoids

France
Zogenix, Inc.

Completed

A Multicenter Active Comparator Study of HC-ER in Adults Following Bunionectomy Surgery

Postoperative Pain
Jiangsu HengRui Medicine Co., Ltd.

Unknown

HR021618 in Moderate to Severe Pain After Abdominal Surgery

Pain After Abdominal Surgery

China
Menarini Group

Completed

Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar (DAVID)

Acute Pain

Italy, Hungary, Spain, Poland, United Kingdom
Mundipharma Korea Ltd

Completed

Efficacy and Safety of Oxycodone/Naloxone (Targin®) in Persistent Moderate to Severe Low Back Pain Following NSAIDs Treatment

Low Back Pain

Korea, Republic of
Hospital de Clinicas de Porto Alegre

Unknown

Hospital Discharge Following Bariatric Surgery by Telepresence Robot

Severe Obesity

Brazil
Trevena Inc.

Completed

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy (APOLLO-1)

Acute Pain

United States
Trevena Inc.

Completed

A Study of TRV130 for the Treatment of Pain After Bunionectomy

Acute Pain

United States
Merz North America, Inc.

Completed

Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds

Correction of Moderate to Severe Nasolabial Folds

United States
University of California, San Diego

Completed

Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks

Total Knee Arthroplasty | Post-surgical Pain | Foot/Ankle Surgery | Catheterization for Postop Analgesia

United States
Laboratorios del Dr. Esteve, S.A.
Premier Research Group plc

Completed

Co-crystal E-58425 vs Tramadol and Celecoxib for Moderate to Severe Acute Pain After Bunionectomy. Phase III Clinical Trial.

Acute Post-surgical Pain

United States
Grünenthal GmbH
Depomed

Terminated

Use of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years Old

Moderate to Severe Acute Postoperative Pain

United States, United Kingdom, Poland
Baudax Bio

Completed

Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain

Pain

United States
INSYS Therapeutics Inc

Terminated

Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain

Post-operative Pain

United States
NanoSHIFT LLC

Terminated

Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars

Dental Pain

United States
Baudax Bio

Completed

Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
Baudax Bio
Lotus Clinical Research, LLC

Completed

Placebo-Controlled Evaluation of Intranasal Dexmedetomidine for Postoperative Analgesia Following Bunionectomy Surgery

Pain, Post-operative

United States
Mallinckrodt

Completed

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

Pain, Postoperative | Bunion

United States
Elite Laboratories, Inc

Completed

A Study to Evaluate Safety and Efficacy Following Dosing of Oxycodone/Naltrexone for Treatment of Adults With Pain Following Bunionectomy Surgery

Pain

United States
Shanghai Jiao Tong University School of Medicine

Unknown

Efficacy and Mechanism Study of Bariatric Surgery to Treat Moderate to Severe Obesity in Han Chinese Population

Morbid Obesity

China
Menarini Group

Completed

Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID-art)

Acute Pain

Serbia, Latvia, Spain, Hungary, Lithuania, Poland, Taiwan, Czech Republic, Germany, Ukraine
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine Surgery

Postoperative Pain | Chlorzoxazone

Denmark
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Janssen Cilag N.V./S.A.

Terminated

Safety and Efficacy Study of Fentanyl Iontophoretic Transdermal System (ITS) for Management of Moderate to Severe Acute Pain in Participants Who Have Undergone Elective Spine or Orthopedic Surgery

Pain, Postoperative

Belgium
Laval University
Université de Montréal

Unknown

Sensitivity of the Step Test to Detect Improvement in Dyspnea Following Bronchodilation in Patients With Chronic Obstructive Pulmonary Disease (CODEx)

Dyspnea | Severe Chronic Obstructive Pulmonary Disease | Moderate Chronic Obstructive Pulmonary Disease

Canada
University of California, San Diego

Terminated

Ultrasound-Guided Continuous Sciatic Nerve Blocks: Popliteal Versus Subgluteal Catheters

Foot Surgery

United States
QRxPharma Inc.

Completed

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Moderate to Severe Postoperative Pain

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Randomized, Double-Blind, Parallel-Arm, Placebo and Active Controlled Dose-Ranging Study of the Efficacy and Safety of Multiple Doses of Tapentadol IR for Postoperative Pain Following Bunionectomy Surgery

Pain | Postoperative Pain
Impliant, Ltd.

Completed

Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis

Low Back Pain | Lumbar Spinal Stenosis | Spondylolisthesis | Leg Pain

United States

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