Search clinical trials for: Moderate-to-high risk surgical patients

Total 125402 results

University Hospital, Clermont-Ferrand

Completed

Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study) (HAEMO)

Postoperative Mortality | Postoperative Morbidity | Hemostasis Change

France
University Hospital, Clermont-Ferrand
Agence Nationale de sécurité du Médicament; Programme Hospitalier de Recherche... and other collaborators

Completed

Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study) (FLASH)

Postoperative Mortality | Postoperative Morbidity

France
Tanta University

Recruiting

Trendelenburg Maneuver Versus Passive Leg Raising Test for Fluid Responsiveness in High-Risk Surgical Patients

Passive Leg Raising | High-Risk Surgical Patients | Trendelenburg Maneuver

Egypt
Odense University Hospital

Recruiting

Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients (DENSVAR)

Endocarditis | Surgical Valve Replacement | Dental

Denmark
Aswan University

Recruiting

Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients

Critical Illness | Acute Kidney Injury

Egypt
Odense University Hospital
Karolinska University Hospital

Not yet recruiting

The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients. (EPICURE)

Gastric Cancer | Peritoneal Metastases | Chemotherapy, Adjuvant | Minimally Invasive Surgical Procedures

United States, Sweden, Denmark, France, Germany
Asian Institute of Gastroenterology, India

Recruiting

ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORE (vocal penn 01)

CHRONIC LIVER DISEASE

India
Affiliated Hospital of Guangdong Medical University

Recruiting

Prediction Models for Risk Score and Prognosis of Intraoperatively Acquired Pressure Injury in Surgical Patients

Pressure Ulcer | Clinical Outcome | Predictive Models | Surgical Patient

China
University of California, San Francisco
American Society of Clinical Oncology; Conquer Cancer Foundation

Recruiting

PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery (PROOF)

Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | Gynecologic Neoplasm

United States
Renrong Gong

Recruiting

Construction of Early Warning Model for Pulmonary Complications Risk of Surgical Patients Based on Multimodal Data Fusion

Respiratory Failure | Cardiac Arrest | Pulmonary Embolism | Infection Complication

China
AUSL Romagna Rimini

Recruiting

Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.

Aortic Stenosis

Italy
University Hospital, Geneva

Recruiting

Enhanced vs.Standard Pain Management of Patients at Risk for Chronic Post-surgical Pain (ALDOpilot)

Chronic Post Surgical Pain

Switzerland
Rijnstate Hospital
University Medical Center Groningen; Maastricht University Medical Center; Leiden... and other collaborators

Recruiting

Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients (PREPARATION)

Postoperative Complications | Interdisciplinary Communication | Surgical Procedures, Operative | Preoperative Care | Cost-Benefit Analysis | Noncardiac Surgery | Comorbidities and Coexisting Conditions | Patient Care Team

Netherlands
Humanitas Clinical and Research Center
Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva

Recruiting

HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery (HISTAP)

Blood Pressure | Complication,Postoperative | Intraoperative Hypotension

Italy
Rigshospitalet, Denmark
Hvidovre University Hospital; Bispebjerg Hospital; The Novo Nordic Foundation; Aalborg... and other collaborators

Recruiting

The Fast-track Centre for Hip and Knee Replacement Database (FCD)

Patient Satisfaction | Hip | Knee | Fast-track Surgery | Enhanced Recovery After Surgery | Perioperative Medicine | Ambulatory Surgical Procedures | Perioperative/Postoperative Complications

Denmark
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Reducing Low-Value Preoperative Investigations in Patients Undergoing Low Risk Surgery (Pre-Op)

Surgery | Anesthesiology

Canada
Balgrist University Hospital

Recruiting

Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery (BAPTIST)

Microbial Colonization | Surgical Site Infection | Antibiotic Resistant Infection

Switzerland
Silk Road Medical

Recruiting

Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease

Carotid Artery Diseases

United States
Imperial College London
University of Edinburgh; Universidad de Granada

Recruiting

Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients (PETS)

Venous Thromboembolism

United Kingdom
Second Affiliated Hospital, School of Medicine,...
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection

Resectable Esophageal Cancer

China
Region Skane
Lund University

Recruiting

ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care (ACUTE)

Complication of Surgical Procedure | Risk Factors | Complication of Treatment | Complication of Anesthesia | Long Term Effects After Emergency Surgery | Long Term Effects After GI Bleeding

Sweden
Istituto Ortopedico Galeazzi

Not yet recruiting

Efficacy of PICO Compared to Opsite Post-Op Visible on Surgical Wound in Patients at High Risk of Local Complications, Undergoing Hip Arthroplasty (PICO-PTA)

Evaluate Postsurgical Hematoma

Italy
University of Bordeaux

Recruiting

Percutaneous Edge To Edge Repair for the Treatment of Severe Tricuspid Valve Regurgitation in High-surgical Risk Patients With Systemic Right Ventricle : a Multicentric French Cohort (PETER-TRESRIV) (PETER-TRESRIV)

Congenital Heart Disease | Tricuspid Regurgitation | Systemic Right Ventricle

France
John Paul II Hospital, Krakow

Recruiting

Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients (SIM-GUARD)

Myocardial Infarction | Coronary Artery Disease | Carotid Stenosis | Valvular Heart Disease | Pulmonary Edema With Heart Failure

Poland
Second Affiliated Hospital, School of Medicine,...

Recruiting

Prophylactic Irradiation to the Contralateral Breast for BCAs Patients (PICB)

Breast Cancer

China, Singapore
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula

Intubation | Cardiovascular Surgical Procedure

United States
Hoffmann-La Roche

Recruiting

A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Patients With High-Risk Muscle-Invasive Bladder Cancer Who Are ctDNA Positive Following Cystectomy (IMvigor011)

Muscle-invasive Bladder Cancer

Belgium, Korea, Republic of, Japan, Brazil, China, United States, Singapore, France, United Kingdom, Canada, Greece, Italy, Spain, Turkey, Russian Federation, Ukraine, Israel, Czechia, Colombia, Hong Kong, Argentina, Germany, Ireland, Polan... and more
University of Birmingham
Christian Medical College and Hospital, Ludhiana, India; University of Lagos... and other collaborators

Not yet recruiting

Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19 (PROTECT-Surg)

Severe Acute Respiratory Syndrome | COVID | Pulmonary Complications in Surgical Patients
National Cancer Institute (NCI)

Recruiting

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Canada
University of Birmingham

Recruiting

Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery (PENGUIN)

Pathologic Processes | Pneumonia | Postoperative Complications | Surgical Wound Infection | Surgical Site Infection | Wound Infection | Anesthesia | Infection | Laparotomy | Communicable Disease | Perioperative Complication | Chlorhexidine

South Africa
Medical College of Wisconsin

Recruiting

Cemiplimab in High Risk or Locally Advanced Hormone Receptor Positive HER2 Negative or Triple-Negative Breast Cancer

Invasive Breast Cancer

United States
Bispebjerg Hospital
Rigshospitalet, Denmark

Recruiting

STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery (STRONG-CS)

Surgery | Risk Reduction | Life Style | Urological Cancer

Denmark
HighLife SAS
ICON plc

Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Mitral Regurgitation

Belgium, France, Germany, Australia, United Kingdom, Poland
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma

United States
Lawson Health Research Institute

Not yet recruiting

Comparing Vacuum-Assisted Percutaneous Excision to Open Surgical Excision for Borderline or High-Risk Breast Lesions (VAPEX)

Breast Fibroadenoma | Lobular Carcinoma in Situ | Atypical Ductal Hyperplasia | Phyllodes Breast Tumor | Atypical Lobular Hyperplasia | Flat Epithelial Atypia | Phyllodes; Fibroadenoma | Radial Scar | Breast Papilloma | Complex Sclerosing Papillary Lesion of the Breast
The University of Hong Kong

Recruiting

Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients

Trauma | Surgical Site Infection | Spinal Tumor | Spinal Deformity

Hong Kong
RenJi Hospital

Recruiting

Preventive Effects of Aspirin as Adjuvant Therapy in Patients With Locally Advanced Renal Cell Carcinoma

Aspirin as Adjuvant Therapy in Patients With Surgically Treated High Risk Renal Cell Carcinoma

China
Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
Children's Hospital Medical Center, Cincinnati
Memorial Sloan Kettering Cancer Center; Fred Hutchinson Cancer Center

Recruiting

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Severe Marrow Failure

United States
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
Medstar Health Research Institute

Completed

Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Stenosis

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Refractory Neuroblastoma | High Risk Neuroblastoma | Resectable Osteosarcoma

United States, Canada
NRG Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group

Suspended

Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer

Stage I Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage II Uterine Corpus Endometrial Stromal Sarcoma AJCC v8 | Stage III Uterine Corpus Endometrial Stromal Sarcoma AJCC v8

United States
Medtronic Cardiovascular

Active, not recruiting

Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients

Aortic Valve Stenosis

United States, Australia, New Zealand, Canada, Netherlands, France, Japan
Universitätsklinikum Hamburg-Eppendorf
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); Deutsche Herzstiftung...

Active, not recruiting

Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality (DEDICATE)

Aortic Valve Stenosis

Germany
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Rhabdomyosarcoma | Alveolar Rhabdomyosarcoma | Embryonal Rhabdomyosarcoma | Botryoid-Type Embryonal Rhabdomyosarcoma | Sclerosing Rhabdomyosarcoma | Spindle Cell Rhabdomyosarcoma

United States, Canada, Puerto Rico, Australia, New Zealand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

An Investigational Surgical Procedure (Vascularized Lymph Node Transfer) in Reducing the Risk of Lymphedema in Patients With Breast Cancer Undergoing Breast Reconstruction

Breast Carcinoma

United States
Ole De Backer
Boston Scientific Corporation; Abbott; Edwards Lifesciences; Symetis SA

Active, not recruiting

Comparison of TAVR With SAVR in Younger Low Surgical Risk Patients With Severe Aortic Stenosis (NOTION-2)

Heart Diseases | Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Ventricular Outflow Obstruction

Finland, Norway, Sweden, Denmark, Iceland
Sichuan Cancer Hospital and Research Institute

Completed

Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL

High-Grade Squamous Intraepithelial Lesions

China

Search clinical trials for: Moderate-to-high risk surgical patients

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