Search clinical trials for: Multicenter Randomized Study

Total 126784 results

Phoenicis Therapeutics

Terminated

A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene

Epidermolysis Bullosa Dystrophica, Recessive | Epidermolysis Bullosa Dystrophica, Dominant

United States, Spain, France
Prollenium Medical Technologies Inc.
Symbio, LLC

Terminated

A Multicenter, Double-blind, Randomized, Controlled, Roll-over Retreatment Study of the Safety and Pain Associated With Injections of PN40082, RV001 With Topical Anesthetic or RV001 for Lip Augmentation

Lip Augmentation

United States
Antea Foundation
Abbott Diabetes Care

Active, not recruiting

GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.

Diabetes Mellitus, Type 2 | Diabetes | Cancer | Diabetes Mellitus, Type 1 | Advanced Cancer | Palliative Care | Terminal Illness | End Stage Cancer | Terminal Cancer

Israel, Italy, Switzerland
Pfizer

Completed

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Osteoarthritis, Knee

Korea, Republic of, United States
Shire

Completed

Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease

Sanfilippo Syndrome

United States, Spain, United Kingdom, Argentina, France, Germany, Italy, Netherlands
Danderyd Hospital
Uppsala University Hospital

Terminated

Swedish Rectal Prolapse Trial

Rectal Prolapse

Sweden
Hepatera Ltd.
Data Matrix Solutions

Completed

A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D

Chronic Hepatitis D Infection With Hepatitis B

Russian Federation, Germany
Boston Scientific Corporation

Completed

COMFORT: A Multicenter, Open-label, Randomized, Crossover Study (COMFORT)

Varicose Veins

United States
Daiichi Sankyo, Inc.

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic Dermatitis

Atopic Dermatitis

United States
Assistance Publique - Hôpitaux de Paris
GETAID Pediatric

Completed

Cyclic Exclusive Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's Disease (CD-HOPE)

Crohn's Disease

France
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
University of Arkansas
OSI Pharmaceuticals

Terminated

Randomized, Double Blind Multicenter Phase II Study of Time to Progression on Fulvestrant in Combination With Erlotinib or Placebo in Hormone Receptor-Positive Metastatic Breast Cancer (MBC) Subjects Who Progressed on First Line Hormonal Therapy

Metastatic Breast Cancer

United States
Chinese PLA General Hospital

Active, not recruiting

Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study

Ablation | Benign Thyroid Nodules

China
Takeda
Ovid Therapeutics Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies (ELEKTRA)

Epilepsy | Dravet Syndrome | Lennox-Gastaut Syndrome

United States, Canada, Israel, Poland, Spain, Australia, China, Portugal
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia

Neuralgia, Postherpetic

Japan
Lyra Medical Ltd.

Completed

Multicenter, Prospective, Non-randomized, Single-arm, Interventional Study for the Evaluation of the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse

Anterior Vaginal Wall Prolapse With/Without Apical/Uterine Descent

Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled, Flexible Dose Escalation Study To Evaluate Sexual And Relationship Satisfaction In The Female Partner Of Men With Erectile Dysfunction Treated With Sildenafil Citrate

Erectile Dysfunction

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Randomized, Open-Label, Crossover, Multicenter, Single Dose Comparator Study Evaluating Onset Of Penile Rigidity In Men With Erectile Dysfunction Who Are Treated With Sildenafil And Tadalafil

Erectile Dysfunction

United Kingdom, Norway
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy

Diabetic Neuropathy, Painful

Japan
Sun Pharma Advanced Research Company Limited

Withdrawn

A Randomized, Open-Label, Comparative, Parallel-Group, Multicenter Study of SPARC1507

Advanced Biliary Tract Cancer

United States
University of Erlangen-Nürnberg Medical School
Technical University of Munich

Completed

Prevention of Falls in General Practitioner for Community-dwelling Older Adults [PreFalls]

Randomized Controlled Trial | Accidental Falls/Prevention & Control | Risk Assessment | General Practitioner Education | Humans | Multicenter Study

Germany
GSNOR Therapeutics, Inc.

Unknown

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Cavosonstat Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)
Technical University of Munich

Completed

Randomized, Double-blind, Two Arms, Multicenter, Phase III Study of Berinert for Treatment of ACE Induced Angioedema

Acute ACE-induced Angioedema

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study.

Metastatic Colorectal Cancer

Germany
Shandong University

Unknown

A Multicenter Randomized Study of Vitamin D Combined With HD-DXM Versus HD-DXM for the Treatment of ITP

Immune Thrombocytopenia

China
Sun Yat-sen University
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Unknown

Olanzapine Plus Fosaprepitant Standard Antiemetic Therapy in the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients Receiving High Emetic Risk Multi-day Chemotherapy: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study (OFFER)

Solid Tumor Patients Receiving High Emetic Risk Multi-day Chemotherapy

China
Krankenhaus Nordwest

Completed

Randomized Multicenter Phase II/III Study With Adjuvant Gemcitabine Versus Neoadjuvant / Adjuvant FOLFIRINOX for Resectable Pancreas Carcinoma

Resectable Prancreas Carcinoma

Germany
Shandong University

Completed

A Multicenter Randomized Open-label Study of Oseltamivir Combined With HD-DEX Versus HD-DEX in the Management of ITP

Thrombocytopenia

China
Bausch Health Americas, Inc.
Galderma R&D; Oceana Therapeutics, Inc.

Completed

A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence

Fecal Incontinence

United States, Germany, Sweden, United Kingdom
Pacira Pharmaceuticals, Inc

Withdrawn

Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries (STRIDE)

Bunion | Metatarsophalangeal Fusion | Midfoot Fusion | Hindfoot Fusion | Total Ankle Arthroplasty | Forefoot Surgery
Cordis Corporation
Quintiles, Inc.; HealthCore-NERI

Completed

A Multicenter, Open Label, Prospective, Non-randomized Study of the InCraft® Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSPIRATION) (INSPIRATION)

Abdominal Aortic Aneurysm

United States, Japan
Second Affiliated Hospital, School of Medicine,...

Unknown

A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma | Neoadjuvant Chemotherapy

China
Novartis Pharmaceuticals

Completed

A Multicenter Randomized 52 Week Treatment Double-blind, Triple Dummy Parallel Group Study to Assess the Efficacy and Safety of QMF149 Compared to Mometasone Furoate in Participants With Asthma

Asthma

China, Germany, United States, India, Korea, Republic of, Romania, South Africa, Croatia, Egypt, Russian Federation, Estonia, Hungary, Poland, Slovakia, Bulgaria, Czechia, Latvia, Guatemala, Serbia, Japan, Mexico, United Kingdom, Li... and more
Eisai Inc.

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

Elderly | Chronic Insomnia | Adults

United States
China Academy of Chinese Medical Sciences
Renmin Hospital of Wuhan University; Children's Hospital of Soochow University and other collaborators

Unknown

Clinical Study of Reduning Injection for the Treatment of Influenza in Children

Influenza in Children
The George Institute
National Health and Medical Research Council, Australia; Baxter Healthcare...

Completed

A Clinical Trial of IntensiVE Dialysis (ACTIVE)

End Stage Renal Disease | Renal Replacement Therapy | End Stage Kidney Disease | Renal Dialysis | Uremia

New Zealand, Canada, Australia, China
Second Affiliated Hospital, School of Medicine,...

Unknown

A Randomized Controlled Multicenter Study of Artificial Intelligence Assisted Digestive Endoscopy

Artificial Intelligence

China
Eisai Inc.

Completed

A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese Adults

Chronic Weight Management

United States
Novartis Pharmaceuticals

Completed

A Randomized, Multicenter, Open-label, Parallel-group, 12-week Study to Assess the Efficacy and Safety of Switching From Tiotropium to QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) in Symptomatic Mild to Moderate COPD Patients

COPD

Korea, Republic of
China Academy of Chinese Medical Sciences
Peking University First Hospital; Peking Union Medical College Hospital; Chengdu... and other collaborators

Unknown

A Clinical Study on Qianjin Capsule of Gynaecology Combined With Antibiotics for Pelvic Inflammatory Diseases (Damp-heat Stasis and Qi Deficiency Syndrome)

Pelvic Inflammatory Diseases
China Academy of Chinese Medical Sciences
Peking University First Hospital; Peking Union Medical College Hospital; Chengdu... and other collaborators

Unknown

A Clinical Study on Kangfu Anti-inflammatory Suppository of Gynaecology Combined With Antibiotics for Pelvic Inflammatory Diseases (Evidence of Dampness and Heat Accumulation)

Pelvic Inflammatory Diseases
ElectroCore INC

Withdrawn

A Randomized, Multicenter, Study for the prEvention and Acute Treatment of Migraine (REAL) (REAL)

Migraine

United Kingdom, Denmark, Germany, Spain, Italy
Edward Chu, MD
Kadmon Corporation, LLC

Completed

A Phase II Multicenter, Randomized, Placebo Controlled, Double Blinded Clinical Study of KD018 as a Modulator of Irinotecan Chemotherapy in Patients With Metastatic Colorectal Cancer

Colorectal Neoplasms

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

A Multicenter Randomized Double-blind Clinical Study Evaluated the Safety, Pharmacokinetic and Pharmacodynamic Characteristics of Roflumilast in COPD Patients

Chronic Obstructive Pulmonary Disease

China
Shanghai Zhongshan Hospital

Unknown

A Prospective, Randomized, Multicenter Study of Comparison of TACE Combination With and Without EBRT for Hepatocellular Carcinoma With Portal Vein Tumor Thrombi

Carcinoma, Hepatocellular

China
King Faisal Specialist Hospital & Research Center

Completed

Randomized Multicenter Study of 5 vs 6 Weekly Fraction of RT in the Treatment of SCC of the Head and Neck

Carcinoma, Squamous Cell

Saudi Arabia
Vital Therapies, Inc.

Terminated

Randomized, Open-Label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD in Subjects w/ AILD

Acute Alcoholic Hepatitis

United States, Spain, United Kingdom, Germany, Austria, Ireland
Puerta de Hierro University Hospital
Hospital Universitario Ramon y Cajal; Hospitales Universitarios Virgen del... and other collaborators

Unknown

Multicenter, Randomized, Controlled and Double-blind Study of Efficacy and Safety of Endoscopic Gastric Tubulization in Patients With Non-alcoholic Steatohepatitis (NASH-APOLLO). (NASH-APOLLO)

Obesity | Non-Alcoholic Fatty Liver Disease

Spain
Pfizer

Terminated

A Double-blind, Double-dummy, Multicenter, Randomized Study of the Efficacy and Tolerability of Valdecoxib 40 mg Versus Rofecoxib 50 mg in Treating the Symptoms of Ankle Sprain

Acute Pain

Brazil
China Academy of Chinese Medical Sciences
Guangdong Provincial Hospital of Traditional Chinese Medicine; Chengdu University... and other collaborators

Unknown

Clinical Study of Sanjin Tablets for the Treatment of Acute Simple Lower Urinary Tract Infection

Urinary Tract Infection Lower Acute

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