Search clinical trials for: Myelodysplastic syndrome (MDS)

Total 37813 results

MedImmune LLC

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single-Dose Subcutaneous Administration of MEDI-528

Healthy

United States
GlaxoSmithKline

Completed

A Study to Assess the Pharmacologic Equivalence of Two Orlistat Dosage Forms

Overweight

United Kingdom
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Fluconazole Tablets 200 mg Under Fasting Conditions

Healthy

Canada
Actavis Inc.

Completed

A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Tablets Under Fed Conditions

Healthy

Canada
Kremers Urban Development Company

Completed

Bioequivalence Study of Pantoprazole 40 mg DR Tablets and Protonix 40 mg Tablets Under Fed Conditions

Healthy

Canada
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fasting Conditions.

Healthy

United States
Teva Pharmaceuticals USA

Completed

Desmopressin Acetate 0.2 mg Tablets, Fasting

Healthy

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fed Conditions

Healthy

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Cefprozil Tablets, USP 500 mg Under Fasting Conditions

Healthy

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Cefprozil Tablets, USP 500 mg Undef Fed Conditions

Healthy

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Amoxicillin 400 mg/Clavulanic Acid 57 mg Chewable Tablets Under Fed Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Fenofibrate 160mg Tablets Under Fed Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Clorazepate Dipotassium 15mg Tablets Under Fasting Conditions

Healthy

United States
Associazione Qol-one

Recruiting

Efficacy and Safety of Luspatercept for the Treatment of Anemia Due to MDS With del5q, Refractory/Resistant/Intolerant to Prior Treatments, RBC-TD (Phoenix)

Myelodysplastic Syndromes | Anemia | Transfusion-dependent Anemia | Del(5Q)

Italy
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) (CL-009)

Tuberculosis

United States
GlaxoSmithKline

Completed

Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol®

Healthy Subjects

United States
Crucell Holland BV

Completed

A Randomized Phase II Trial to Compare the Safety and Neutralizing Activity of CL184 in Combination With Rabies Vaccine vs. HRIG or Placebo in Combination With Rabies Vaccine in Healthy Adult Subjects

Rabies

United States
VIVUS LLC

Completed

Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin

Erectile Dysfunction

United States
Groupe Francophone des Myelodysplasies
Celgene

Recruiting

Study Evaluating Combination of Luspatercept in LR-MDS Without RS Having Failed or Being Ineligible to ESA

Myelodysplastic Syndromes | MDS

France
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

AML | MDS

United States
University of Florence

Active, not recruiting

Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients (FLO_CC-486-)

MDS | CMML

Italy
AstraZeneca
Bristol-Myers Squibb

Completed

Pharmacokinetic Drug Interaction Study of Dapagliflozin and Valsartan or Simvastatin in Healthy Subjects

Type 2 Diabetes Mellitus

United States
Astellas Pharma Inc

Completed

A Study to Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult Volunteers

Healthy Subjects | Pharmacokinetics of YM178

United States
Nordic MDS Group

Completed

Lenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5

AML | MDS

Denmark, Norway, Sweden
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

Study of Oral Dasatinib in Subjects With Myelodysplastic Syndrome (MDS) and Excess Marrow Blasts

Myelodysplastic Syndromes

United States
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
GlaxoSmithKline

Completed

A Pharmacokinetic Study Investigating the Rate and Extent of Paracetamol Absorption of Three Experimental Sustained Release Pediatric Suspensions

Healthy Subjects

United States
GlaxoSmithKline

Completed

Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol® Extend

Healthy Subjects

United States
GlaxoSmithKline

Completed

A Pharmacokinetic Study of an Experimental Paracetamol Formulation

Headache, Tension-Type

United States
Weill Medical College of Cornell University
Sunesis Pharmaceuticals

Completed

Vosaroxin for Intermediate 2 or High-risk MDS After Failure With Hypomethylating Agent-based Therapy

Myelodysplastic Syndrome

United States
Sunnybrook Health Sciences Centre
Health Sciences Centre, Winnipeg, Manitoba; The Ottawa Hospital; Jewish General... and other collaborators

Unknown

MDS-CAN: A Prospective National MDS Clinical Database and Local Tissue Bank (MDS)

Myelodysplastic Syndrome (MDS)

Canada
Uwe Platzbecker
Gilead Sciences

Withdrawn

Magrolimab Plus Intensive Chemotherapy in Newly Diagnosed AML or HR-MDS (MAGROLIC)

Acute Myeloid Leukemia | Myelodysplastic Neoplasm
BioVie Inc.

Completed

NE3107 Activity and Safety in Patients With Parkinson's Disease Using Levodopa

Parkinson Disease

United States
Bristol-Myers Squibb

Completed

Relative Bioavailability Study of Four Experimental Formulations for Alzheimer's Disease

Healthy | Alzheimer's Disease

United States
H. Lee Moffitt Cancer Center and Research Institute
Novartis Pharmaceuticals

Recruiting

Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA

Myelodysplastic Syndromes

United States
Fondazione Italiana Sindromi Mielodisplastiche-ETS

Terminated

Early and Low Dose Deferasirox (3.5 mg/kg FCT) to Suppress NTBI and LPI as Early Intervention to Prevent Tissue Iron Overload in Lower Risk MDS

Myelodysplastic Syndromes

Italy
Helsinn Healthcare SA

Terminated

A Safety and Efficacy Study of Pracinostat and Azacitidine in Patients With High Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
Celgene

Completed

Multi-center, Survival Data Collection in Subjects Previously Enrolled in Celgene Protocol CC-5013-MDS-003

Myelodysplastic Syndrome

United States, Germany
Seoul National University Hospital

Completed

Head to Head Comparison of Azacitidine and Decitabine in Myelodysplastic Syndrome (H-1012-015-342)

Myelodysplastic Syndromes

Korea, Republic of
Amgen

Completed

Romiplostim Treatment of Thrombocytopenia in Subjects With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Thrombocytopenia | MDS
Asan Medical Center

Completed

Hematopoietic Cell Transplantation With Post-transplantation Cyclophosphamide in MDS

Myelodysplastic Syndromes

Korea, Republic of
Genzyme, a Sanofi Company

Terminated

A Study of Oral Clofarabine in Adult Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United States
Sumitomo Pharma America, Inc.

Terminated

A Phase 1b/2 Study of Alvocidib Plus Decitabine or Azacitidine in Patients With MDS

Myelodysplastic Syndromes (MDS)

United States
Benjamin Tomlinson

Recruiting

5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies

Myelodysplastic Syndromes | MDS/MPN Crossover Syndromes

United States
MedImmune LLC

Completed

A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354

Healthy | Asthma

United States
Bristol-Myers Squibb

Completed

Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects

Alzheimer Disease

United States
Eisai Inc.

Completed

Escalation Study to Determine Bioavailability of a Single Oral Dose of Decitabine in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States
Yale University

Withdrawn

CPX-351 in Patients Treated for Higher-risk Myelodysplastic Syndromes Experiencing Hypomethylating Agent Failure.

MDS

United States
PersImmune, Inc
University of California, San Diego

Unknown

Personalized Adoptive Cellular Therapy Targeting MDS Stem Cell Neoantigens (PACTN)

Myelodysplastic Syndromes

United States

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