Search clinical trials for: Neglected Tropical Diseases

Total 372351 results

R-Evolution Worldwide S.r.l. Impresa Sociale
University Ghent; National Institute for Medical Research, Tanzania; University... and other collaborators

Not yet recruiting

Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis (NeuroSolve)

Neurocysticercosis
Drugs for Neglected Diseases
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Not yet recruiting

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) (STROgHAT)

Human African Trypanosomiasis
Bioaster

Not yet recruiting

Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination (Obi1)

Healthy Volunteers | Onchocerciasis | Mansonelliasis | Loiasis

Cameroon
Institute of Tropical Medicine, Belgium
University of Gondar

Recruiting

Clinical Prognostic Score to Predict Relapse in VL (CPS)

Visceral Leishmaniasis

Ethiopia
Murdoch Childrens Research Institute
Burnet Institute; Lao Tropical and Public Health Institute

Not yet recruiting

Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study) (ITCHY)

Scabies | Scabies; Itch

Lao People's Democratic Republic
Eijkman Oxford Clinical Research Unit, Indonesia
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy (MetLep)

Leprosy | Leprosy, Multibacillary | Neglected Tropical Diseases

Indonesia
Fundacion Agencia Aragonesa para la Investigacion...
Universidad de Zaragoza; Instituto de Salud Carlos III; Université d'Abomey-Calavi and other collaborators

Recruiting

Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy (BLMs4BU)

Buruli Ulcer

Benin
London School of Hygiene and Tropical Medicine
Bandim Health Project; Medical Research Council Unit, The Gambia; Ministerio... and other collaborators

Recruiting

Adjunctive Ivermectin Mass Drug Administration for Malaria Control (MATAMAL)

Lymphatic Filariasis | Scabies | Malaria,Falciparum | Strongyloidiasis | Neglected Tropical Diseases | Hook Worm | Soil Transmitted Helminths

Guinea-Bissau
University Hospital Center of Martinique
Centre Hospitalier Universitaire de la Réunion; Centre Hospitalier de Cayenne; University Hospital of Guadeloupe and other collaborators

Recruiting

Comparing Two Antibiotic Therapy Periods (3 Versus 7 Days) in Patients With Mild Leptospirosis and Seen at the Hospital in 5 French Overseas Departments (Martinique, Guadeloupe, French Guiana, Reunion, Mayotte) (LEPTO3)

Mild Leptospirosis

Martinique, French Guiana, Guadeloupe, Mayotte, Réunion
Center for Research on Filariasis and Other Tropical...

Not yet recruiting

Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa (EOLoa)

Diagnoses Disease | Onchocerciasis | Neglected Diseases | Loiasis

Cameroon
Institute of Tropical Medicine, Belgium
University Hospital, Antwerp; Maastricht University; University of York; University...

Active, not recruiting

Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in Ethiopia (SpatialCL)

Cutaneous Leishmaniases

Ethiopia
Jennifer Keiser
Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health...

Completed

Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura (FACEITeffic)

Trichuriasis

Uganda
Pemba Ministry of Health Zanzibar

Active, not recruiting

Health Education Model Led by Community Health Volunteers.

Health Education | Schistosomiasis

Tanzania
Drugs for Neglected Diseases
Bayer

Active, not recruiting

Emodepside Phase II Trial for Treatment of Onchocerciasis

Onchocerciasis

Ghana, Congo, The Democratic Republic of the
Drugs for Neglected Diseases
Makerere University; The Netherlands Cancer Institute; Kenya Medical Research... and other collaborators

Completed

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

Visceral Leishmaniasis

Ethiopia, Kenya, Sudan, Uganda
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Withdrawn

Screen and Treat Implementation for HAT Control

Trypanosomiasis, African | Sleeping Sickness
Technical University of Munich
Swiss Tropical & Public Health Institute; Makerere University; European and Developing... and other collaborators

Active, not recruiting

Adoption of L-PZQ for Schistosomiasis by Endemic Counties - Social Science Research Study (ADOPT)

Social Acceptance | Schistosomiasis in Children

Uganda, Kenya, Côte D'Ivoire
Institute of Tropical Medicine, Belgium

Completed

Assessment of Recombinant HAT-RDT Specificity

Human African Trypanosomiasis

Congo, The Democratic Republic of the
Washington State University
University of Glasgow; National Institute for Medical Research, Tanzania

Completed

Integrating Community Interventions to Eliminate Neglected Tropical Diseases

Rabies in Animals | Worms; Intestine

United States
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Drugs for Neglected Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Efficacy and Safety of Fexinidazole in Patients With Human African Trypanosomiasis (HAT) Due to Trypanosoma Brucei Rhodesiense

Trypanosoma Brucei Rhodesiense; Infection

Malawi, Uganda
Institute of Tropical Medicine, Belgium
Medecins Sans Frontieres, Netherlands; University of Gondar, Gondar, Ethiopia; Bureau of Health, Abdurafi, Ethiopia

Terminated

Predicting Visceral Leishmaniasis in HIV Infected Patients (PreLeisH)

Leishmaniasis, Visceral

Ethiopia
Foundation for Innovative New Diagnostics, Switzerland
London School of Hygiene and Tropical Medicine; Academisch Medisch Centrum... and other collaborators

Completed

Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa (VL-DX-EAFR)

Leishmaniasis, Visceral

Ethiopia, Kenya
FHI 360
National Program for the Fight Against Neglected Tropical Diseases, Côte...

Completed

Resiliency Through Azithromycin for Children (REACH), Côte d'Ivoire (REACH)

Child Mortality | Azithromycin

Côte D'Ivoire
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Baylor College of Medicine
George Washington University; Amsterdam Institute for Global Health and Development and other collaborators

Completed

Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon
University Hospital Tuebingen

Completed

Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity (TRANSMAL)

Malaria Transmission

Gabon, Ghana
Drugs for Neglected Diseases

Unknown

Short Course Regimens for Treatment of PKDL (Sudan)

PKDL - Post-Kala-Azar Dermal Leishmanioid

Sudan
University Medical Center Groningen
University of Ghana; Drugs for Neglected Diseases; University of Groningen; Komfo... and other collaborators

Completed

WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8

Mycobacterium Ulcerans Infection

Benin, Ghana
Drugs for Neglected Diseases

Completed

Thermotherapy + a Short Course of Miltefosine for the Treatment of Uncomplicated Cutaneous Leishmaniasis in the New World¨

Cutaneous Leishmaniasis

Colombia, Peru
Baylor College of Medicine
George Washington University

Completed

Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults

Hookworm Infection | Hookworm Disease

United States
Emory University
Emory Ethiopia; Amhara Regional Health Bureau; Federal Democratic Republic of...

Completed

The Impact of Enhanced, Demand-side Sanitation and Hygiene Promotion on Sustained Behavior Change and Health in Ethiopia

Mental Well-being | Sustained Behavior Change

Ethiopia
Drugs for Neglected Diseases
Institute of Tropical Medicine, Belgium; UNITAID; AMS-PHPT Research Platform... and other collaborators

Unknown

Lopinavir/r/ Lamivudine/ Abacavir as an Easy to Use Paediatric Formulation (LOLIPOP)

HIV

Uganda
Drugs for Neglected Diseases
London School of Hygiene and Tropical Medicine; Institute of Tropical Medicine... and other collaborators

Completed

Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.

Visceral Leishmaniasis

Ethiopia
Lihir Medical Centre
London School of Hygiene and Tropical Medicine

Completed

Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )

Yaws | Scabies | Lymphatic Filariases | Trachoma | Strongyloidiasis

Papua New Guinea
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Medecins Sans Frontieres, Netherlands; Addis Ababa... and other collaborators

Completed

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

HIV-infection/Aids | Visceral Leishmaniosis

Ethiopia
Noguchi Memorial Institute for Medical Research
Ghana Health Service, Neglected Tropical Diseases Program

Completed

Prevalence of LF Infection in Districts Not Included in LF Control Activities

Onchocerciasis | Lymphatic Filariases

Ghana
London School of Hygiene and Tropical Medicine
AIM Initiative; Ministry of Health, Liberia

Unknown

Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia

Yaws | Leprosy | Lymphatic Filariases | Buruli Ulcer

Liberia
University Hospital, Basel, Switzerland
Swiss Tropical & Public Health Institute; Ifakara Health Institute

Completed

Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa (RenalOne)

HIV Infections | Hypertension | Diabetes Mellitus | Chronic Kidney Diseases | Tuberculosis | Schistosomiasis

Switzerland
Emory University

Completed

Zambia One Love Aim 3 Trial

Sexually Transmitted Diseases | HIV | Neglected Diseases | Non-communicable Diseases

Zambia
National School of Public Health, Morocco
Institute of Tropical Medicine, Belgium

Completed

Accuracy of a Rapid Diagnostic Test for Cutaneous Leishmaniasis in Morocco

Skin Diseases, Parasitic | Cutaneous Leishmaniasis | Neglected Diseases

Morocco
Universidad Nacional de Salta
CIVETAN CONICET, Facultad de Ciencias Veterinarias, UNCPBA. Tandil

Completed

Serum Pharmacokinetic Disposition and Urinary Excretion of Albendazole

Neglected Tropical Diseases | Soil Transmitted Helminthiasis
Baylor College of Medicine

Completed

Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon
Baylor College of Medicine
George Washington University

Completed

Safety and Immunogenicity Study of Na-GST-1 With or Without CpG

Hookworm Infection | Hookworm Disease

United States
Drugs for Neglected Diseases
Gilead Sciences; Paladin Labs Inc.

Completed

Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa

Primary Visceral Leishmaniasis

Kenya, Sudan
Swiss Tropical & Public Health Institute
Institute of Tropical Medicine, Belgium; B.P. Koirala Institute of Health Sciences and other collaborators

Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (NIDIAGDigest)

Shigellosis | Schistosomiasis | Strongyloidiasis | Dientamoebiasis | Giardiasis | Amoebiasis | Soil-transmitted Helminthiasis | Intestinal Salmonellosis | Campylobacteriosis | Aeromonas Spp. Infections | Cryptosporidium Spp. Infections

Côte D'Ivoire, Indonesia, Mali, Nepal
Drugs for Neglected Diseases
World Health Organization; Swiss Tropical & Public Health Institute; Epicentre; Medecins Sans Frontieres, Netherlands and other collaborators

Completed

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Trypanosomiasis, African

Congo, The Democratic Republic of the, Congo
Drugs for Neglected Diseases

Completed

Topical 3% Amphotericin B Cream for the Treatment of Cutaneous Leishmaniasis in Colombia (Anfoleish)

Cutaneous Leishmaniasis

Colombia
Institute of Tropical Medicine, Belgium
University Hospital, Geneva; Institut National de Recherche Biomédicale. Kinshasa...

Completed

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC (Nidiag-Neuro)

Neurological Disorders | Bacterial Meningitis | Cryptococcal Meningitis | Neurosyphilis | Cerebral Malaria | Central Nervous System Tuberculosis

Congo, The Democratic Republic of the

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