Search clinical trials for: Omeprazole

Total 441 results

Assiut University

Unknown

Oral Omeprazole in Bleeding Peptic Ulcer

Bleeding Peptic Ulcer
Bausch Health Americas, Inc.

Completed

Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill

Upper Gastrointestinal Bleeding

United States
Maria Sklodowska-Curie National Research Institute...
Centre of Postgraduate Medical Education

Completed

Argon Plasma Coagulation for Barrett's Esophagus

Barretts Esophagus With Low Grade Dysplasia
Mansoura University Children Hospital

Completed

Role of Pepsin Assay in Wheezy Infants

Gastroesophageal Reflux Disease
Rijnstate Hospital
Erasmus Medical Center

Completed

Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.

Gastroesophageal Reflux | Hernia, Diaphragmatic | Esophageal Atresia

Netherlands
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy Participants

Healthy

United States
Aragon Institute of Health Sciences

Completed

Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study

Barrett's Esophagus

Spain
Tiziana Life Sciences LTD

Withdrawn

Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

NAFLD | NASH - Nonalcoholic Steatohepatitis | T2DM (Type 2 Diabetes Mellitus)
University of Cologne
Umm Al-Qura University

Completed

Effect of Acute Ethanol Consumption on The Activity of Major Cytochrome P450 Enzymes, NAT2 and P-glycoprotein

AOD Effects and Consequences

Germany
National Cheng-Kung University Hospital
National Science Council, Taiwan

Completed

The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia

Hypoalbuminemia | Peptic Ulcer Bleeding

Taiwan
Xiyuan Hospital of China Academy of Chinese Medical...

Unknown

Efficacy of Traditional Chinese Medicine Combined With Omeprazole in Patients With Non-erosive Reflux Disease

Non-erosive Reflux Disease

China
Food and Drug Administration (FDA)
BioPharma Services, Inc

Completed

Drug Interaction With Proton Pump Inhibitors for Nifedipine ER Tablets

Healthy Volunteers

United States
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects

Type 2 Diabetes

Canada
Hull University Teaching Hospitals NHS Trust

Terminated

Bronchial Hyper-responsiveness in Reflux Cough

Cough

United Kingdom
Bayer

Completed

BAY73-4506 Probe Substrate Study

Neoplasms

Canada
Dexa Medica Group

Terminated

DLBS2411 Treatment for Ulcer Healing in Non-Bleeding Peptic Ulcers

Non-Bleeding Peptic Ulcers

Indonesia
Menarini International Operations Luxembourg SA

Completed

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout (FORWARD)

Gout

Poland, Serbia, Germany, Italy, Netherlands, Romania
Medical University of Bialystok
National Science Centre, Poland

Completed

Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal Bleeding

Non-variceal Upper Gastrointestinal Bleeding

Poland
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)

Pharmacokinetic

Belgium
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
Eli Lilly and Company

Completed

A Study of Ixekizumab in Participants With Plaque Psoriasis

Psoriasis

United States
Emilio Vargas Castrillón
Fundación Mutua Madrileña

Completed

Study to Compare the Bioavailability of Omeprazole 20 mg Before and After Undergoing Surgery for Morbid Obesity (OBS-2011/001)

Bariatric Surgery Candidate

Spain
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
Brigham and Women's Hospital

Completed

Oral OKT3 for the Treatment of Active Ulcerative Colitis

Ulcerative Colitis

United States
Capital Medical University

Unknown

A New System for GERD Diagnosis and Treatment (EAISMLP)

GERD
Celgene

Completed

A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

Heathy Volunteer

United States
Torax Medical Incorporated

Completed

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease (CALIBER)

GERD Gastroesophageal Reflux Disease

United States
Claire Daniels

Unknown

EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

Eosinophilic Esophagitis

United States
The First Affiliated Hospital of Guangzhou Medical...

Unknown

Indomethacin for Refractory Chronic Cough

Refractory Chronic Cough

China
Bayer
Orion Corporation, Orion Pharma

Completed

Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers

Prostatic Neoplasms

Germany
Ascension Genesys Hospital

Terminated

Anti-reflux Control to Decrease Post Tonsillectomy Pain

Laryngopharyngeal Reflux | Throat Pain

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach

Lymphoma

United States
Cognition Therapeutics

Completed

Drug Interaction Study of CT1812 in Healthy Volunteers

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study to Evaluate the Effect of Increased Stomach pH on Evacetrapib in Healthy Participants

Healthy

United States
Janssen-Cilag International NV

Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Healthy

Belgium
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
Javeriana University
Universidad Nacional de Colombia

Completed

Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication

Therapy | H.Pylori Infection | CYP2C19 Polymorphism
Mahidol University

Completed

Treatment in Patients With Globus: Psychoeducation, Anxiolytics or Proton Pump Inhibitors

Globus

Thailand
Syndax Pharmaceuticals

Completed

A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

Healthy Volunteers | Volunteers | Normal Volunteers | Human Volunteers

United States
Novo Nordisk A/S

Completed

Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects

Healthy | Diabetes

Germany
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States
Queen's University
Canadian Institutes of Health Research (CIHR)

Terminated

Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole

Gastric Acid

Canada
Chinese PLA General Hospital

Completed

Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease

Dyspepsia | Gastroesophageal Reflux Disease | Bile Reflux

China
Damascus Hospital

Completed

Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers

Peptic Ulcer Hemorrhage | Marginal Ulcer | Gastroduodenal Ulcer

Syrian Arab Republic
Damascus Hospital

Withdrawn

Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding

Peptic Ulcer Hemorrhage | Marginal Ulcer | Gastroduodenal Ulcer

Syrian Arab Republic
University of Sao Paulo General Hospital
InCor Heart Institute

Completed

Ranitidin Versus Omeprazole in Patients Taking Clopidogrel

Coronary Artery Disease | Drug Interaction Potentiation
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
Khon Kaen University
Thai Rheumatism Association

Completed

Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis

Gastroesophageal Reflux | Systemic Sclerosis | Proton Pubm Inhibitor
NHS Tayside
University of Dundee

Completed

Impact of OCT1 on Metformin Tolerance (ImpOCT)

Tolerance

United Kingdom
Temple University

Withdrawn

Comparison of Voice Therapy and Antireflex Therapy in LPR

Laryngopharyngeal Reflux

United States

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