Search clinical trials for: Open apex

Total 8879 results

Cairo University

Not yet recruiting

Clinical and Radiographic Evaluation of Revascularization of Immature Anterior Permanent Teeth Using Concentrated Growth Factor (CGF) Versus Blood Clot (BC)

Revascularization
Al-Azhar University

Recruiting

Three Dimensional Evaluation of Apexogenesis of Immature Young Permanent Teeth With Different Endodontic Material

Deep Carious Young 1st Permanent Molar With Open Apex

Egypt
MindImmune Therapeutics, Inc.

Recruiting

Exploratory Open Label Study for Development of a Method To Detect Dendritic Cells

Probable Alzheimer's Disease

United States
Alcon Research

Recruiting

Hydrus® Microstent New Enrollment Post-Approval Study (CONFIRM)

Primary Open Angle Glaucoma

United States
Sanifit Therapeutics S. A.

Completed

Phase 3 Study of SNF472 for Calciphylaxis (Calciphyx)

Calciphylaxis | Calcific Uremic Arteriolopathy

United States, Belgium, United Kingdom, Spain, Germany, Poland
Novavax

Active, not recruiting

Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years (COVID-19)

COVID-19

Spain, United States, South Africa, Mexico, United Kingdom, Philippines, Colombia, Dominican Republic, Guatemala, Honduras
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
VectivBio AG

Completed

A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

Germany, Slovakia
Santen Inc.

Completed

Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension (ANGEL-2)

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
EyePoint Pharmaceuticals, Inc.

Completed

Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma

Primary Open Angle Glaucoma | Ocular Hypertension

United States
BioCryst Pharmaceuticals

Active, not recruiting

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies (APeX-A)

Hereditary Angioedema | HAE

France, North Macedonia, Poland, Korea, Republic of, Slovakia, South Africa, Czechia
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
Parker Institute for Cancer Immunotherapy
Bristol-Myers Squibb; Cancer Research Institute, New York City; Apexigen, Inc.

Completed

Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Metastatic Pancreatic Adenocarcinoma

United States
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

Severe Hypertriglyceridemia

United States, Hungary, Belarus, Bulgaria, Czechia, Georgia, Poland, Russian Federation, Ukraine
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
Mansoura University
Cairo University

Active, not recruiting

Evaluation Of Different Pulpotomy Agents Used For Treatment Of Immature Molars

Infected Pulp | Root Canal Treatment

Egypt
Eisai Inc.
Eisai Limited

Completed

Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
FibroGen
AstraZeneca; Astellas Pharma Inc

Completed

Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease

Anemia | End Stage Renal Disease | Chronic Kidney Disease

Puerto Rico, United States
Total Cardiovascular Solutions

Completed

Patent Hemostasis With Vasoband Versus TR Band (OPEN-Radial)

Radial Artery Injury at Wrist and Hand Level

India
Nourhan M.Aly
Alexandria University

Completed

Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth

Pulp Necroses

Egypt
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
ForSight Vision5, Inc.

Completed

Dose-Ranging Study of the Bimatoprost Ocular Insert

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
ForSight Vision5, Inc.

Completed

An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
Al-Azhar University

Completed

Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth

Apexification | Pulp Necrosis
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-1)

Cardiovascular Disease

Finland, United States, Netherlands, Spain, Korea, Republic of, China, Israel, Belgium, Germany, Australia, Czechia, Taiwan, Denmark, United Kingdom, Hungary, Poland, France, Mexico, Turkey, Canada, New Zealand, Colombia, Switzerland, Irelan... and more
ForSight Vision5, Inc.

Completed

Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
Hospital Infantil Universitario de San Jose
Fundación Santa Fe de Bogota

Unknown

Radiologic and Clinical Outcomes of Augmentation in Fragility Intertrochanteric Hip Fracture Treatment (AFIF)

Hip Fractures

Colombia
Torabinejad, Mahmoud

Terminated

Revitalization of Teeth With Necrotic Pulps and Open Apexes Using Platelet-Rich Plasma

Infection

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole Open-Label, Safety and Tolerability Study (APEX 241)

Schizophrenia | Bipolar Disorder

United States
Ono Pharma USA Inc

Completed

Effects of ONO-2506PO in Patients With Alzheimer's Disease

Alzheimer's Disease

United States, Canada
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery

Anesthesia

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Lund University Hospital

Not yet recruiting

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI) (PERELI)

Dedifferentiated Liposarcoma

Sweden, Norway
Vitalija Stonkuvienė

Recruiting

Cardiac Rehabilitation and Frailty Physical Training Program in Elderly Patients After Open Heart Surgery

Frailty Syndrome

Lithuania
Rocky Vista University, LLC

Recruiting

Ultrasound Investigation Into Swimming Induced Pulmonary Edema in Open Water Swimming Athletes (SIPE)

Swimming Induced Pulmonary Edema

United States
University Hospital "Sestre Milosrdnice"

Not yet recruiting

The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism

Rhinoplasty | Nasal Skin-soft Tissue Envelope Metabolism | Lactic Acid | Autologous Cartilage Grafting
Oslo University Hospital
University of Oslo

Recruiting

Honest Open Proud for Psychotic and Bipolar Disorder in Norway (HOP-NOR)

Psychotic Disorders | Bipolar Disorder | Disclosure

Norway
University Health Network, Toronto

Not yet recruiting

Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation (TRADR)

Distal Radius Fractures

Canada
Chunling Jiang

Not yet recruiting

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Necrotizing Pancreatitis
University of Roma La Sapienza

Recruiting

Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study

Inguinal Hernia | Post Operative Pain

Italy
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Pain and Muscle Biopsy (BIODOMU)

Neuromuscular Diseases
Universidad de Antioquia
Farmacias Pasteur

Not yet recruiting

Evaluation of the Effect of Consensual Pharmaceutical Indication Protocols for the Treatment of Minor Ailments (InFaPro)

Community Pharmacy Services
University of South Florida
National Institute on Deafness and Other Communication Disorders (NIDCD)

Not yet recruiting

Understanding Aided Speech Perception in Noise

Aging | Hearing Impairment, Sensorineural | Spatial Perception | Hearing Aids

United States
Bio-Thera Solutions

Not yet recruiting

An Evaluation of BAT 8010 for Injection in Combination With BAT 1006 in Locally Advanced or Metastatic Entities Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of the Tumor in Patients Multicenter, Open Phase Ib/IIa Clinical Study

Advanced Solid Tumors
GlaxoSmithKline

Not yet recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Argentina, Japan, Taiwan, Canada, Korea, Republic of, Australia
Nanfang Hospital, Southern Medical University

Recruiting

Prospective Cohort Study of Complications and Outcomes in Cirrhosis

Decompensated Cirrhosis | Overt Hepatic Encephalopathy | CMV Reactivation

China
Temple University

Not yet recruiting

Peer Facilitated Waitlist Controlled Transportation Study

Serious Mental Illness
Brigham and Women's Hospital
Open Medicine Foundation

Not yet recruiting

LIFT: Life Improvement Trial (LIFT)

ME/CFS

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