Search clinical trials for: Oral disease modifying treatments

Total 386963 results

University Hospital, Caen
Genzyme, a Sanofi Company; Ligue contre le cancer, France

Completed

Impact of the Arrival on the French Market of New First Line Oral Treatments on the Delay Between MS Onset and First Disease Modifying Treatment (DMTs) Administration (PREMISEP)

C10.114.375.500

France
Alzheimer's Disease Expert Lab (ADEL), Inc.
Oscotec Inc.

Recruiting

A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01

Alzheimer Disease

United States
AbbVie

Recruiting

A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain (PROVIDENCE)

Chronic Lymphocytic Leukemia

Spain
VA Office of Research and Development

Recruiting

Dynamic Treatment Regiments for Glucocorticoid Tapering (SMART-RA)

Rheumatoid Arthritis

United States
Federal University of Minas Gerais

Recruiting

Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome

Burning Mouth Syndrome

Brazil
Cairo University

Recruiting

Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments

Apical Periodontitis | Pulpitis - Irreversible

Egypt
University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

Gepant treAtments: EffectIveNess and tolERability (GAINER) (GAINER)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

MAP THE SMA: a Machine-learning Based Algorithm to Predict THErapeutic Response in Spinal Muscular Atrophy (MAP_THE_SMA-01)

Spinal Muscular Atrophy

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
Bambino Gesù Hospital and Research Institute; University of Messina; University... and other collaborators

Recruiting

Long Term Trajectories of SMA Patients Receiving or Not Disease-modifying Treatments

Spinal Muscular Atrophy

Italy
Oral Health Centre of Expertise in Western Norway
University of Bergen; Norwegian University of Science and Technology

Recruiting

Caries-Obesity Prevention in Children by Modifying Risk Behaviors Among Parents With Immigrant Background-COP Study (COP)

Oral Health

Norway
Hospital Clínico Universitario de Valladolid

Recruiting

NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting (NUMITOR)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Pain | Neurologic Manifestations | Headache Disorders | Headache Disorders, Secondary

Spain
Camillians Saint Mary's Hospital Luodong

Recruiting

Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis

Allergic Rhinitis | Vasomotor Rhinitis

Taiwan
Washington University School of Medicine
National Institute on Aging (NIA); Alzheimer's Association; Eisai Inc.; Accelerating...

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, Netherlands, Puerto Rico, Spain, United Kingdom, France, Ireland, Mexico, Brazil, Japan, Germany
Amsterdam UMC, location VUmc
Corcept Therapeutics; Netherlands Brain Foundation

Recruiting

RESET-medication Glucocorticoid Receptor (GR) Blockade as Disease Modifying Treatment for Depression With Childhood Trauma (RESET-m)

Major Depressive Disorder | Childhood Trauma

Netherlands
University Hospital Ostrava
University of Ostrava

Not yet recruiting

Therapeutic Monitoring of Drugs Used in the Treatment of Multiple Sclerosis

Multiple Sclerosis

Czechia
Novo Nordisk A/S

Not yet recruiting

Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments

Diabetes Mellitus, Type 2
University of Minnesota
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

Smoking | Smoking Cessation | Smoking Reduction

United States
Copenhagen University Hospital at Herlev
Institut Straumann AG; Amgen

Recruiting

Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication

Cancer | Osteoporosis | Missing Teeth | Implants

Denmark
University of Wisconsin, Madison

Recruiting

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

Cancer of Head and Neck

United States
University Hospital, Lille
InBrain Pharma

Recruiting

Dopaminergic restauratIon by intraVEntriculaire Administration (DIVE)

Parkinson Disease

France
University of British Columbia
St. Justine's Hospital; Montreal Children's Hospital of the MUHC

Recruiting

A Prospective Evaluation of Non-Operative Treatments for Gastrocutaneous Fistulae in Children (GCF)

Gastrocutaneous Fistula | Gastrostomy Complications

Canada
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor

Oral Cancer

China
Centre Hospitalier Universitaire de Besancon

Recruiting

Evaluation of Medical Practice in the Management of Bone Metastases After Injectable Bone Antiresorptive Treatment, and Its Influence on Quality of Life (PRISM)

Tumor With Bone Metastasis

France
Washington University School of Medicine
Eli Lilly and Company; Hoffmann-La Roche; Avid Radiopharmaceuticals; National Institute... and other collaborators

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001 (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, France, Ireland, Mexico, Netherlands, Puerto Rico, Spain, United Kingdom, Brazil, Japan, Germany
UNC Lineberger Comprehensive Cancer Center
AstraZeneca

Active, not recruiting

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

Oral Cancer | Larynx | Lip | Digestive Organs--Diseases

United States
Montreal Heart Institute

Terminated

Evaluation of the Response of Itraconazole and Terbinafine Therapy in Subjects With Crohn's Disease (CD-IT)

Inflammatory Bowel Diseases | Crohn's Disease

Canada
Washington University School of Medicine
Hoffmann-La Roche; National Institute on Aging (NIA); Alzheimer's Association

Terminated

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, France, Spain, Ireland, Canada, Australia, Puerto Rico, United Kingdom
Pfizer

Terminated

A Study to Learn About the Study Medicine Etrasimod in Adults With Moderate to Severe Atopic Dermatitis (AD) Who Have Already Tried Treatments Taken by Mouth or by Injection

Eczema | Atopic Dermatitis | Eczema, Atopic | Atopic Dermatitis, Unspecified

United States, Canada, Czechia, Poland
Case Western Reserve University
Patient-Centered Outcomes Research Institute

Active, not recruiting

Older Adult Effectiveness of 2 Treatments

Dental Caries

United States
Instituto de Investigación Hospital Universitario...

Completed

Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19

SARS-CoV-2 Infection

Spain
Hikma Pharmaceuticals LLC

Active, not recruiting

Safety and Effectiveness of Generic Fingolimod (Sphingomod®, Hikma) in Patients With Relapsing-Remitting Multiple Sclerosis in Egypt

Relapsing-Remitting Multiple Sclerosis

Egypt
Washington University School of Medicine
Hoffmann-La Roche; Genentech, Inc.; National Institute on Aging (NIA); Alzheimer...

Suspended

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, France, Spain, Ireland, Argentina, Australia, Colombia, Germany, Mexico, Netherlands, Puerto Rico, United Kingdom
E2Bio Life Sciences, LLC
Hematology Center after Prof. R. Yeolyan

Withdrawn

Study of a New Medical Device for Oral Mucositis (MDOM)

Oral Mucositis | Stem Cell Transplant Complications

Armenia
Indiana University
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder

Temporomandibular Disorder

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Smart Marker Annunciating Response to Rheumatologic Treatments SMART²T (SMART²T)

Rheumatoid Arthritis

France
Hikma Pharmaceuticals LLC

Completed

Effectiveness and Safety of Generic Delayed-Release Dimethyl Fumarate (Sclera® or Marovarex ®, Hikma) in Routine Medical Practice in the Treatment of Relapsing-Remitting Multiple Sclerosis in MENA Region

Relapsing Remitting Multiple Sclerosis

Algeria, Egypt, Jordan
Allergan

Completed

Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments. (ELEVATE)

Episodic Migraine

United States, Australia, Canada, Czechia, Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Russian Federation, Spain, Sweden, United Kingdom
Teijin America, Inc.
Parexel

Completed

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral Doses of TCK-276 in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Novartis Pharmaceuticals

Completed

Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS Patients (EXCHANGE)

Multiple Sclerosis | Relapsing Multiple Sclerosis | Advancing Multiple Sclerosis

United States, Puerto Rico
Groupe Maladies hémorragiques de Bretagne

Completed

Vitamin K Antagonist Versus Direct Oral Anticoagulant Treatments in Hemophilia (KADOAH)

Hemophilia A | Hemophilia B | Anticoagulant-induced Bleeding

France
Pfizer

Completed

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

COVID-19

United States, Korea, Republic of, Russian Federation, Czechia, Turkey, Malaysia, South Africa, Bulgaria, Poland, Hungary, Argentina, Brazil, Colombia, Japan, Mexico, Puerto Rico, Spain, Thailand, Ukraine, India
University Hospital, Basel, Switzerland
Swiss Multiple Sclerosis Society; Bangerter-Rhyner Stiftung; Center for Chronic...

Active, not recruiting

Prospective Stratification of Infectious Risks in Multiple Sclerosis (InRIMS)

Multiple Sclerosis

Switzerland
Drugs for Neglected Diseases
Wellcome Trust grant 212346/Z/18/Z - 21st Century Treatments for Sustainable...

Completed

Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects

Visceral Leishmaniasis | Cutaneous Leishmaniases

United Kingdom
Karolinska Institutet

Completed

Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery

Peri-Implantitis

Sweden
Novartis Pharmaceuticals

Completed

Risk Perception in Multiple Sclerosis

Multiple Sclerosis

United States
University Hospital, Lille
Ministry of Health, France

Active, not recruiting

Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis (FAIR-ALS II)

Amyotrophic Lateral Sclerosis

France
Washington University School of Medicine
Eli Lilly and Company; Hoffmann-La Roche; Avid Radiopharmaceuticals; National Institute... and other collaborators

Completed

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, France, Spain, Ireland, Australia, Puerto Rico, United Kingdom
Monash University

Enrolling by invitation

Relationship Between Oral DMT Burden and Adherence in MS (STATURE)

Multiple Sclerosis | Adherence, Medication

Australia
Boston Scientific Corporation

Terminated

A Study of Orally Administered BGC20-0134 (Structured Lipid) in Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Relapsing Remitting Multiple Sclerosis

Spain, Germany, Belgium, Poland, France, Russian Federation
Amgen

Completed

Study to Evaluate Safety and Effectiveness of Oral Apremilast (CC-10004) in Patients With Moderate to Severe Plaque Psoriasis (ESTEEM 1)

Plaque Psoriasis

Search clinical trials for: Oral disease modifying treatments

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