Search clinical trials for: PARPi resistance

Total 7007 results

National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Advanced Solid Tumors | SCLC | HRD Cancer

United States
Xing Xie

Recruiting

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Efficacy and Safety

China
Riphah International University

Not yet recruiting

Comparison of High Intensity Strength Training and Muscle Energy Techniques in TKR Patients

Knee Osteoarthritis | Resistance Training | Arthroplasty, Knee Replacement

Pakistan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Choroid Plexus Dysfunction in Neurological Diseases (PLEXFOLD)

Metabolic Syndrome | Plexus Choroideus

France
TOLREMO therapeutics AG

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors (TT-CSP-001)

Cancer | Adult Solid Tumor | Advanced Solid Tumor | Adult Disease

Spain, Switzerland
Maastricht University Medical Center
Cargill

Not yet recruiting

Plant Protein Blend and Milk Protein Supplements in Older Individuals (Blend-D2O)

Sarcopenia | Skeletal Muscle Atrophy | Protein Malnutrition
Mayo Clinic
Temple University

Not yet recruiting

Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

Diabetes | Insulin Resistance | Glucose Intolerance

United States
National University of Singapore
National University Polyclinics, Singapore

Not yet recruiting

Intensive Aerobic and Resistance Exercise Program (IAREP)

Type 2 Diabetes Mellitus | Cognitive Impairment | Cognitive Dysfunction | Non-insulin-dependent Diabetes Mellitus
Assiut University

Not yet recruiting

Insulin Resistance in Relation to Hyperthyroidism and Hypothyroidism

Insulin Resistance
Assiut University

Not yet recruiting

Clinical and Laboratory Evaluation of Antifungal Resistance in Tinea Capitis

Fungal Resistance
Milton S. Hershey Medical Center
National Institute on Aging (NIA)

Not yet recruiting

Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance (FASTNIA)

Mobility Limitation
Maastricht University Medical Center

Not yet recruiting

Effects of Ketone Monoesters on Brain Function

Cerebral Blood Flow | Cognitive Performance | Appetite Control | Brain Vascular Function | Brain Insulin Sensitivity

Netherlands
Korea University Anam Hospital
Korean Society of Hypertension

Recruiting

Home Blood Pressure Variability and Its Link to Arteriosclerosis and Metabolic Dysfunction in Hypertensive Patients

Arteriosclerosis | Hypertension | Metabolic Syndrome X | Blood Pressure Monitoring, Home

Korea, Republic of
Erasme University Hospital

Not yet recruiting

Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study (Memori³)

Alzheimer Disease | Mild Cognitive Impairment
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients

Obesity | Atypical Endometrial Hyperplasia | Progesterone Resistance

China
Abderrahmane Mami Hospital

Recruiting

Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units (NOSOREA3)

Critical Illness | Cross Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection

Tunisia
Cairo University

Not yet recruiting

Composite Repair Using Silane Coupling Agent

Hypersensitivity | Tooth Discoloration | Dental Restoration Failure of Marginal Integrity | Tooth Fracture
New Valley University

Not yet recruiting

Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections

Immunocompromised ICU Patients With Respiratory Tract Infections
Cairo University

Not yet recruiting

Antibiotic Use and Resistance KAP Among Dental Interns

Antibiotic Side Effect | Antibiotic Resistant Infection
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
Riphah International University

Recruiting

Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.

Comparison of Aerobic Exercise and Resistance Training

Pakistan
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
Badr University

Not yet recruiting

High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity (diabetic)

Diabetes | Insulin Resistance | Abdominal Obesity
Stanford University

Not yet recruiting

Stronger: Muscle Strengthening for Menopause

Resistance Training

United States
University of Missouri-Columbia
Gilead Sciences

Recruiting

Accelerated ART Initiation for PWHIV Who Are Out of Care (ACCELERATE)

HIV Infections | ART | Noncompliance, Patient

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Resistance Swallowing Training in Patients With Tracheotomy

Swallowing Training on Muscle Strength
University of Aarhus
Aarhus University Hospital; University of Copenhagen

Not yet recruiting

Resistance Training and Corticospinal Excitability in Multiple Sclerosis (NEXIMS)

Multiple Sclerosis
Cairo University

Not yet recruiting

Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study

Periodontitis | Antibiotic Resistance | Antibiotic Use
Region Skane
Lund University

Not yet recruiting

Screening of Multidrug Resistant Bacteria, and the Clinical Implication for the Patient

Multi-antibiotic Resistance
Lawson Health Research Institute
Greenstone Biosciences, Inc.

Not yet recruiting

iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease (INFERENCE)

Cardiovascular Diseases | Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cerebrovascular Accident | Arrythmia | Cardiometabolic Syndrome
Universidad de La Frontera

Not yet recruiting

Resistance Exercise Training in the Older Population With Obesity (RETOPO)

Obesity | Aging

Chile
University of Utah

Recruiting

The Acute T-Rex (Timing of Resistance Exercise) Study

Diabetes Mellitus, Type 2 | Insulin Resistance | Glucose Intolerance | Sleep Disturbance | Overweight or Obesity | Insulin Sensitivity

United States
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States
Leeuwenhoek Laboratories Co. Ltd.

Not yet recruiting

Investigation of Metabolomics Differences Between Metabolic Syndrome and Healthy Individuals in Taiwan

Metabolic Syndrome
Sengkang General Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Lee Kong Chian...

Recruiting

Pilot Study of the Human Metagenome in Metabolic Diseases

Obesity | Metabolic Syndrome | Sarcopenia | Chronic Inflammation | Sarcopenic Obesity

Singapore
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
Assiut University

Not yet recruiting

Association Between Triglycerides Glucose Ratio With HOMA -IR as Indicators of Insulin Resistance in Obese Adults

Insulin Resistance
University of California, San Francisco
Bill and Melinda Gates Foundation; Ministère de la Santé Publique du Niger; Centre... and other collaborators

Not yet recruiting

Azithromycin for Child Survival in Niger II (AVENIR II)

Mortality | Antimicrobial Resistance

Niger
University of Alabama at Birmingham
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women (OVERCOME-IT)

Overweight or Obesity | Resistance Training | Prediabetes or Diabetes | Prehypertension (Elevated Blood Pressure) or Hypertension

United States
University Hospital, Montpellier

Not yet recruiting

Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients (KREBSome-IRC)

Metabolic Syndrome | Dialysis; Complications

France
University Ghent
University Hospital, Ghent

Not yet recruiting

Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MASLD (CENSORIAL)

Exercise Therapy | Metabolic Dysfunction-associated Steatotic Liver Disease
Imperial College London
The Behavioural Insights Team

Not yet recruiting

Testing New Ways to Name Antimicrobial Resistance

Antimicrobial Resistance | Attitude to Health
Fudan University

Not yet recruiting

Inosine Reverse Chemo Resistance in Triple Negative Breast Cancer

Triple-negative Breast Cancer
College of Staten Island, the City University of...
Bay Ridge Center

Not yet recruiting

Hydraulic Resistance and Older Adults

Muscle Weakness | Aging | Fall | Old Age; Debility

United States
Federation Francophone de Cancerologie Digestive

Recruiting

Prospective Cohort Study of Immunotherapy Resistance in Metastatic Colorectal Cancer Patients With MSI (CORESIM)

Colorectal Cancer Metastatic | Microsatellite Instability-High Colorectal Cancer

France
Integrative Phenomics
Assistance Publique - Hôpitaux de Paris; Assistance Publique Hopitaux De Marseille and other collaborators

Not yet recruiting

Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk (PINEAPPL)

Hypertension | Healthy | Obesity | Overweight | Metabolic Syndrome | Hypercholesterolemia | Risk Factor, Cardiovascular | Abdominal Obesity | Normal Weight Adults | Low-grade Inflammation | Metabolically Healthy Controls
Fudan University

Not yet recruiting

Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer

Triple-negative Breast Cancer
Columbia University
University of California, Berkeley

Recruiting

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin Resistance | Prediabetic State | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

United States
SpeeDx Pty Ltd
German Federal Ministry of Education and Research; Wellcome Trust; Biomedical... and other collaborators

Not yet recruiting

Susceptibility Testing In Neisseria Gonorrhoeae (STING) Study, Assessing the Performance of a New Rapid Test for Gonorrhoea Antibiotic Resistance, in a Cohort of 100 Culture Positive Neisseria Gonorrhoeae Infections (STING)

Gonorrhea | Diagnosis | Resistance Bacterial
Iman Al-Naggar, PhD
National Institute on Aging (NIA); American Urological Association; Urology Care... and other collaborators

Recruiting

Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome (Mito-LUTS)

Lower Urinary Tract Symptoms | Overactive Bladder Syndrome

United States

Search clinical trials for: PARPi resistance

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