Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.

To Compare the Effects of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.

the study will show the effects of aerobic and resistance training on exercise capacity, depression and quality of life in patients with hypothyroidism. The evaluation of TSH level before and after the exercise sessions will provide valuable data.

Study Overview

• Status: Recruiting
• Conditions: Comparison of Aerobic Exercise and Resistance Training
• Intervention / Treatment: Other: aerobic exercises; Other: resistance training; Drug: medication

Detailed Description

The study aims to investigate the effects of aerobic exercise and resistance training by comparing the two types of exercises, the finding of this study gain insights into the most effective approach for patients with hypothyroidism particularly in relation to exercise capacity, depression and quality of life. The study design is Randomized Controlled Trial. Sample size is calculated using G power program. the study duration is 6 months after the approval of research board. Non probability Purposive sampling is used for this study. Data will be analyzed by using SPSS version 20.

• Study Type: Interventional
• Enrollment (Estimated): 66
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Imran Amjad, PhD; Phone Number: 03324390125; Email: imran.amjad@riphah.edu.pk

Study Locations

• Pakistan
  • Khyber Pakhtunkhwa
    • Abbottābād, Khyber Pakhtunkhwa, Pakistan, 21300
      • Recruiting
      • Abbottabad medical complex
      • Contact: saira jahan, MS; Phone Number: 031591289095; Email: saira.jahan@riphah.edu.pk
      • Principal Investigator: Usama Iqbal

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

Both males and females Age between 40 to 60 years Diagnosed cases of hypothyroidism Duration: 2 years being diagnosed Patients who easily perform exercises

Exclusion Criteria:

Patients with serious comorbidities like cancer Uncontrolled hypertension Vitally unstable patients Red flags for physiotherapy

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: aerobic exercises; Aerobic exercises i-e treadmill walking, bicycle ergometer, Treadmill	Other: aerobic exercises; group A will receive aerobic training like walking and cycling for 03 times per week approximately each exercise 5 to 10 minutes for 8 weeks.
Experimental: resistance training; resistance exercise training gluteal bridge, calf raises, squats, seated shoulder press,	Other: resistance training; this group will receive resistance training like gluteal bridge, calf raise, squats, seated shoulder press for 03 times per week approximately each exercise 5 to 10 minutes for 8 weeks.
Placebo Comparator: medication; only on drugs no exercise is given	Drug: medication; This group will be just on medication and no exercise will be given to this group

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
6 Minute Walk Test	The six minute walk test 96 The six minute walking test (6MWT) was developed by the American Thoracic Society and it was officially introduced in 2002, coming along with a comprehensive guideline. The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity. The 6-minute walk test (6MWT) is commonly used to measure the functional exercise capacity in chronic patients with cardiovascular disease.	8 weeks
The Beck Depression Inventory Scale	The Beck Depression Inventory (BDI, BDI-1A, BDI-II), created by Aaron T. Beck, is a 21-question multiple-choice self-report inventory, one of the most widely used psychometric tests for measuring the severity of depression. Its development marked a shift among mental health professionals, who had until then, viewed depression from a psychodynamic perspective, instead of it being rooted in the patient's own thoughts. Each question had a set of at least four possible responses, ranging in intensity. Higher total scores indicate more severe depressive symptom.	8 weeks
SF- 36 SF-36	SF- 36-Item Short Form Survey (SF-36) is an outcome measure instrument that is often used, well-researched, self-reported measure of health. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. It comprises 36 questions that cover eight domains of health. The SF-36 is often used as a measure of a person or population's quality of life (QOL).	8 weeks

Collaborators and Investigators

• Sponsor: Riphah International University
• Investigators: Principal Investigator: saira jahan, Riphah International University

Study record dates

Study Major Dates

• Study Start (Actual): April 1, 2024
• Primary Completion (Estimated): June 1, 2024
• Study Completion (Estimated): June 1, 2024

Study Registration Dates

• First Submitted: April 18, 2024
• First Submitted That Met QC Criteria: April 18, 2024
• First Posted (Actual): April 22, 2024

Study Record Updates

• Last Update Posted (Actual): April 22, 2024
• Last Update Submitted That Met QC Criteria: April 18, 2024
• Last Verified: April 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Endocrine System Diseases; Thyroid Diseases; Hypothyroidism
• Other Study ID Numbers: RCRAHS-ISB/REC/MS-PT/01813

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No