Search clinical trials for: PK sampling

Total 5167 results

University Hospital, Montpellier

Not yet recruiting

Pharmacokinetic Modeling of Methadone (PKMETHAHOME)

Toxicomania
Zydus Therapeutics Inc.

Recruiting

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Cirrhosis | Hepatic Impairment | Cholestatic Liver Disease

United States
Université Catholique de Louvain

Recruiting

Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units (Pop-PK/PD)

Pharmacokinetics | Infection | Infection, Bacterial | Anti-Bacterial Agents | Drug Monitoring | Infections, Respiratory

Belgium
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer

Stage IB Breast Cancer AJCC v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | HER2-Positive Breast Carcinoma | Hormone Receptor-Positive Breast Carcinoma

United States, Puerto Rico
Peking University Cancer Hospital & Institute

Completed

Dynamic ctDNA Detection for Colorectal Cancer Liver Metastases

Colorectal Cancer | Surgery | Liver Metastases | Minimal Residual Disease | Circulating Tumor DNA

China
Kamari Pharma Ltd
Bioskin GmbH

Completed

KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)

Lichen Simplex Chronicus

Germany
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Pharmacokinetic Study of Paracetamol in Patients Over 80 Years Hospitalized to an Acute Geriatric Ward

Pain

Belgium
University Hospital, Bordeaux

Completed

Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study. (PK-LAP)

Critical Illness | Laparotomy | Piperacillin, Tazobactam Drug Combination

France
Natalia Valadares de Moraes
University of Sao Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo

Enrolling by invitation

Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol

Obesity | Bariatric Surgery | Roux-en Y Gastric Bypass

United States
Wake Forest University Health Sciences

Completed

PK Sampling After IV Oxytocin and Effects on Sensory Function in Healthy Volunteers

Chronic Pain

United States
University of Cologne
University of Leipzig; University of Witten/Herdecke; University Hospital Munich

Unknown

Model for PK/PD of Antimicrobials in Blood Stream Infection: Feasibility (MOBSI1)

Blood Stream Infections

Germany
M.D. Anderson Cancer Center
Myriad Genetic Laboratories, Inc.

Withdrawn

Correlation of Genomic Variation in Enzymes Responsible for Metabolism of Capecitabine With Drug Metabolism

Breast Cancer
P.O. Witteveen
Erasmus Medical Center; The Netherlands Cancer Institute

Terminated

Biomarker Development for Response Prediction by DNA Mutational Analysis (CPCT-01)

Neoplasm Metastasis

Netherlands
Jeil Pharmaceutical Co., Ltd.

Completed

The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Male Volunteers Volunteers

Hypertension With Dyslipidemia

Korea, Republic of
University of Michigan
Gilead Sciences

Completed

Pharmacokinetics of Single-Dose Oral Ranolazine in Hemodialysis Patients

Cardiovascular Disease | End-stage Renal Disease

United States
University of Michigan
Theravance Biopharma

Completed

Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5

End-Stage Renal Disease | Stage 5 Chronic Kidney Disease

United States
University of Pittsburgh
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients

Fungal Infection | Lung Transplant Infection

United States
Children's Hospital Medical Center, Cincinnati
Hoffmann-La Roche

Completed

PK-PD Study of Mycophenolic Acid (CellCept) in Pediatric Kidney Transplant Patients

Kidney Transplant

United States
University of Rochester
Hoffmann-La Roche

Completed

PK of MMF in Cadaveric vs Living Donor Liver Transplant Recipients

Transplantation, Liver

United States
Peking University First Hospital
Peking University Third Hospital; Peking University Cancer Hospital & Institute

Recruiting

A Study of Molecular Subtyping-based Therapeutic Strategies for Cutaneous T-cell Lymphoma (AMITY)

Cutaneous T Cell Lymphoma | Cutaneous T-Cell Lymphoma/Mycosis Fungoides

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers (I-COMET)

Colon Cancer | Peritoneal Carcinoma

France
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
Hadassah Medical Organization
London North West Healthcare NHS Trust

Not yet recruiting

Severe COVID-19 Infection in Children Presenting to EDs in Israel and England (SPICE)

COVID-19 | Inflammatory Response
JW Pharmaceutical

Not yet recruiting

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Healthy

Korea, Republic of
Ironshore Pharmaceuticals and Development, Inc

Not yet recruiting

Ph3 Multicenter, 3wk RDBPC Efficacy, Safety & PK Study of Evening Dosed MPH HCl ER Capsules (HLD200) in Children 4-5 Yr With ADHD

Attention Deficit Hyperactivity Disorder
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
Centre Leon Berard

Not yet recruiting

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO) (TACO)

Oral Squamous Cell Carcinomas

France
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy
Institut de cancérologie Strasbourg Europe
Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Recruiting

Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer (TNBC-RT2023)

Triple-negative Breast Cancer

France
Universidad del Desarrollo
Technical University of Munich

Recruiting

Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model (Eleved PD)

Healthy | Surgery

Chile
Brugmann University Hospital

Recruiting

Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone

Kidney Stone

Belgium
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
University Hospital, Toulouse

Not yet recruiting

Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations (OrganoEye)

Eye Abnormalities

France
Riphah International University

Not yet recruiting

Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy

Spastic Cerebral Palsy

Pakistan
Vrinnevi Hospital
Ryhov Hospital

Recruiting

Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation Recurrence Following Electrical Cardioversion (IERV)

Inflammation | Atrial Fibrillation | Genetic Predisposition to Disease

Sweden
Peking University First Hospital

Not yet recruiting

Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes

Obstructive Sleep Apnea | Pregnancy | Chronic Tonsillitis
University of Pennsylvania

Recruiting

Evaluation of Accelerated Sampling Techniques for Vessel Wall Imaging

Vasculopathy

United States
Dong-A ST Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants

Healthy

Korea, Republic of
Alto Neuroscience

Recruiting

PD, PK, and Safety of ALTO-203 in Patients With MDD

Anhedonia | Major Depressive Disorder

United States
Peking University First Hospital

Not yet recruiting

The Effect of OSA on Pregnancy and Fetal Outcomes

Obstructive Sleep Apnea | Pregnancy
Hannover Medical School
Boehringer Ingelheim

Not yet recruiting

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) (EMPA-PKD)

Autosomal Dominant Polycystic Kidney
University Hospital, Toulouse

Recruiting

Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases (TekAPo)

Skin Diseases | Autoimmune Bullous Dermatosis | Dysimmune Dermatological Diseases | Auto-inflammatory Dermatological Diseases

France
Assistance Publique Hopitaux De Marseille

Recruiting

Prospective Multicenter Cohort Study to Validate Four Groups of Biomarkers for Assessing Lung Cancer Risk Among Patients With Atheromatous Cardiovascular Disease in a Screening Pathway (BIOCEPTION)

Lung Cancer | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 Years

France
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Assistance Publique - Hôpitaux de Paris
INRAe - Micalis Institute - Jouy en Josas

Not yet recruiting

EDN and Eosinophilic Esophagitis (OesEDN)

Eosinophilic Esophagitis

France
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

PK/PD Study of SHR-2017 Injection in Patients With Bone Metastases

Patients With Bone Metastases

China
The Seventh Affiliated Hospital of Sun Yat-sen...
Huizhou Municipal Central Hospital; Dongguan Hospital of Traditional Chinese... and other collaborators

Recruiting

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

Osteoporosis Fracture | Compression Fracture | Osteoporosis Vertebral | Perform PVP / PKP Treatment

China
Peking University Hospital of Stomatology

Recruiting

Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Dentin Sensitivity

China

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