Search clinical trials for: PMD

Total 211 results

Primus Pharmaceuticals
Sun Valley Arthritis Center

Recruiting

Effect of Metaxalone 640 mg (M640) on Truck Driving Ability and Cognition Compared to Other Skeletal Muscle Relaxants

Cognitive Impairment

United States
Polarean, Inc.
Aerogen

Recruiting

Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging

Chronic Obstructive Pulmonary Disease

United States
Chiesi Farmaceutici S.p.A.

Recruiting

Comparison Between CHF5993 pMDI 200/6/12,5mg HFA-152a VS CHF5993 pMDI 200/6/12,5mg HFA-134a in Subjects With Asthma (Trecos) (TRECOS)

Asthma

United Kingdom
Ionis Pharmaceuticals, Inc.

Recruiting

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Pelizaeus-Merzbacher Disease

France, Netherlands
University Hospital Tuebingen

Recruiting

Stress, Inflammation and Neuroimaging in Major Depressive Disorder as Compared to Premenstrual Dysphoric Disorder

MDD | PMDD

Germany
Affini-T Therapeutics, Inc.

Recruiting

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12V

United States
Children's Hospital of Philadelphia
National Institute of Neurological Disorders and Stroke (NINDS); North American...

Recruiting

Promoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS | Mitochondrial Encephalomyopathies | MERRF

United States
Pak Medical and Diagnostic Center

Not yet recruiting

Role of Bandage After FUE Hair Transplantation

Hair Loss/Baldness
Omeicos Therapeutics GmbH

Recruiting

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) (PMD-OPTION)

Primary Mitochondrial Disease

Germany, Italy
Peking Union Medical College Hospital

Recruiting

68Ga-PMD22 PET/CT Examination Targeting CLDN18.2

Gastrointestinal Cancer

China
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.

Epidural Analgesia | Labor Pain | Nociceptive Pain | NOL Index

Belgium
Chiesi Farmaceutici S.p.A.
SGS S.A.

Recruiting

Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®

Asthma

Belgium
Pia Jaeger, MD, PhD

Recruiting

Nociception Level-guided Remifentanil Dosing in Children During General Anesthesia

Surgical Procedure, Unspecified

Denmark
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Characterize Biomarkers and Disease Progression in Participants With Pelizaeus-Merzbacher Disease

Pelizaeus-Merzbacher Disease

France, Australia, Germany, Netherlands
Chiesi Farmaceutici S.p.A.

Recruiting

PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI) (TRIBE)

Chronic Obstructive Pulmonary Disease

United Kingdom
University Hospital, Basel, Switzerland

Recruiting

Nociception Level During Opioid-sparing Anaesthesia Versus Conventional Opioid-based Anaesthesia (NOL_Basel)

Analgesia

Switzerland
Yonsei University

Recruiting

Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial

Total Hip Arthroplasty, Postoperative Pain

Korea, Republic of
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Potential Anti-tumor Effects of SSGJ-705 in Patients With Advanced or Metastatic HER2-expressing Solid Tumors

Receptor, ErbB-2
Kuopio University Hospital

Recruiting

Comparison of the Nociception Monitoring Devices During Cardiac Surgery. (SYDNOS)

Cardiac Surgery

Finland
AstraZeneca

Recruiting

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS) (LOGOS)

Asthma

United States, China, Czechia, Germany, South Africa, United Kingdom, Mexico, Turkey, Colombia, Russian Federation, Brazil, Israel, Greece, Portugal, Austria, Costa Rica, Saudi Arabia, Slovakia, Sweden, Puerto Rico
AstraZeneca

Recruiting

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS) (KALOS)

Asthma

United States, Canada, Denmark, Hungary, New Zealand, Poland, Spain, Korea, Republic of, Philippines, Italy, Argentina, Bulgaria, India, Japan, Vietnam, Taiwan, Thailand, Peru, Chile, Puerto Rico, Belgium, Australia, Netherlands, Romania
Minovia Therapeutics Ltd.

Not yet recruiting

A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion

Primary Mitochondrial Diseases

Israel
University Hospital, Strasbourg, France

Recruiting

Validation of the RADIAL Algorithm for Diagnosis of Autosomal Recessive Cerebellar Ataxia (RADIAL-VALID)

Autosomal Recessive Cerebellar Ataxia

France
Tampere University
Oulu University Hospital; Kuopio University Hospital; Tampere University Hospital and other collaborators

Recruiting

Comparing the Efficacy of Two Valved Holding Chambers in Acute Wheezing (CHAMBER)

Bronchospasm; Bronchitis | Bronchitis Obstructive | Bronchiolitis; Obstruction

Finland
Children's Hospital of Philadelphia
Eli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaborators

Recruiting

The Myelin Disorders Biorepository Project (MDBP)

Mucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditions

United States
Joanne Kurtzberg, MD
The Marcus Foundation

Recruiting

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells (DUOC-01)

Mucopolysaccharidosis II | Brain Diseases, Metabolic, Inborn | Adrenoleukodystrophy | Batten Disease | Leukodystrophy, Metachromatic | Leukodystrophy, Globoid Cell | Alpha-Mannosidosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | Neimann Pick Disease | Sanfilippo Mucopolysaccharidoses

United States
Baylor College of Medicine
Aicardi Syndrome Foundation

Recruiting

Study of Selected X-Linked Disorders: Aicardi Syndrome

Brain Disorders | Aicardi Syndrome

United States
AstraZeneca

Completed

Change in Symptom and Quality of Life in COPD by Budesonide/Glycopyrronium/Formoterol Fumarate Pressurized Metered Dose Inhaler (BGF pMDI) (EBISU)

Pulmonary Disease, Chronic Obstructive

Japan
Chiesi Farmaceutici S.p.A.

Active, not recruiting

A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared to CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid (FORCE2)

Asthma

United States
Duke University
International Rescue Committee

Completed

Parents Make the Difference II: Trial of a Parenting Intervention

Child Abuse | Parenting

Liberia
Annovis Bio Inc.
TFS Trial Form Support

Completed

A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Parkinson's Disease, Idiopathic

United States, Spain, Poland, Germany, Hungary, Italy
Children's Hospital of Philadelphia
Illumina, Inc.

Active, not recruiting

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Mucopolysaccharidoses | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2 Gangliosidosis | Zellweger... and other conditions

United States
The Cleveland Clinic

Completed

Postoperative Consequences of Intraoperative NOL Titration

Anesthesia; Adverse Effect

United States
Chiesi Farmaceutici S.p.A.

Active, not recruiting

Step-up to Medium Strength Triple Therapy vs High Strength ICS/LABA in Adult Asthmatics Uncontrolled on Medium Strength ICS/LABA (MiSTIC)

Asthma

Hungary
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma. (FORTUNE)

Asthma

China
Midwestern University

Active, not recruiting

The Effects of Mixhers HERTIME Supplements on Menstrual Symptoms

Healthy | Premenstrual Dysphoric Disorder | Premenstrual Syndrome

United States
Chiesi Farmaceutici S.p.A.

Completed

A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV)

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Neutec Ar-Ge San ve Tic A.Ş

Active, not recruiting

Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination in pMDI Form in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD

Turkey
Chiesi Farmaceutici S.p.A.

Completed

Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance

Mucociliary Clearance

United Kingdom
Orion Corporation, Orion Pharma

Completed

Use of Buventol Easyhaler and Bufomix Easyhaler in Methacoline Challenge Testing (EASYRELIEF)

Asthma

Finland
Stanford University

Terminated

Embodied Virtual Reality Therapy for Functional Neurological Symptom/ Conversion Disorder (VR4FND)

Conversion Disorder | Non-epileptic Seizures | Functional Neurological Disorder | Functional Movement Disorder | Psychogenic Movement Disorder

United States
Phoenix Molecular Designs

Active, not recruiting

Phase 1/1b Study of Oral PMD-026 in Patients With Metastatic Breast Cancer and Metastatic Triple Negative Breast Cancer

Metastatic Breast Cancer | Triple Negative Breast Cancer

United States
University of Leeds
NHS West Yorkshire Integrated Care Board

Active, not recruiting

Letters in Addition to Emailed Audit and Feedback in Refining Asthma Treatment in Primary Care (CLEARAIR)

Asthma

United Kingdom
Pulmonary Research Institute of Southeast Michigan
GlaxoSmithKline

Completed

Peak Inspiratory Flow and Dry Powder Inhaler Performance in COPD

COPD

United States
Talaris Therapeutics Inc.
Duke University

Terminated

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

Niemann-Pick Disease | Alpha-mannosidosis | Tay Sachs Disease | Sandhoff Disease | Metachromatic Leukodystrophy (MLD) | Hurler-Scheie Syndrome | Hurler Syndrome (MPS I) | Hunter Syndrome (MPS II) | Sanfilippo Syndrome (MPS III) | Krabbe Disease (Globoid Leukodystrophy) | Adrenoleukodystrophy (ALD and AMN) | Pelizaeus...

United States
Gregor Berger
Swiss National Science Foundation

Completed

The Omega-3 Fatty Acid Paediatric Depression Trial (Omega-3-pMDD)

Depression

Switzerland
Chiesi Farmaceutici S.p.A.

Completed

CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD (TRIFORCE)

Chronic Obstructive Pulmonary Disease

Germany
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Stress & Premenstrual Symptoms Study

Stress | Mood | PMDD

United States
Joanne Kurtzberg, MD
Duke University; Miltenyi Biotec, Inc.

Available

Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants

Hematologic Malignancies | Immune Deficiencies | Inborn Errors of Metabolism Disorders

United States

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