Search clinical trials for: Pain due to Osteoarthritis of the Knee

Total 492898 results

Icahn School of Medicine at Mount Sinai

Recruiting

Physical Therapy vs Remote Exercise for Knee Pain Due to Osteoarthritis (OA)

Chronic Pain | Knee Osteoarthritis

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, United Kingdom
Ampio Pharmaceuticals. Inc.

Completed

AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee

Knee Osteoarthritis | Osteoarthritis, Knee | Knee Arthritis | Knee Pain Chronic

United States
Sorrento Therapeutics, Inc.

Withdrawn

A Phase 3 Study to Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee

Osteoarthritis, Knee | Knee Pain Chronic
Tris Pharma, Inc.
Forest Laboratories

Completed

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

United States
Regeneron Pharmaceuticals

Terminated

A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee

Pain | Osteoarthritis of the Knee

United States, Georgia, Moldova, Republic of, Poland, Ukraine
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
Dr. Kevin Rod

Unknown

The Effect of Low Intensity Ultrasound Therapy on Chronic Pain Due to Osteoarthritis of the Knee.

Osteoarthritis in the Knee

Canada
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee (OAK)

Osteoarthritis of the Knee | Chronic Lower Back Pain

Belgium, Czechia, Germany, Hungary, Spain, United Kingdom
Bayer

Completed

An Evaluation of a Gender Specific Insole to Provide Relief From Knee Pain Due to Osteoarthritis or General Anterior Knee Pain in Male Subjects When Used in Foot Wear Over a Period of Four Weeks

Osteoarthritis, Knee

United States
Applied Biologics, LLC

Unknown

Safety & Efficacy FloGraft (Micronized Human Amnion Chorion Membrane)® in Adults With Pain Due to OA of the Knee (OA)

Osteoarthritis, Knee

United States
Federal University of São Paulo

Unknown

Ultrasound-guided Genicular Nerve Block With Phenol for the Treatment of Chronic Pain Due to Knee Osteoarthritis

Chronic Pain | Osteoarthritis, Knee

Brazil
Ono Pharmaceutical Co. Ltd

Terminated

A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee (MOTION)

Pain | Osteoarthritis, Knee

Poland, Hungary, Spain, Denmark, United Kingdom
Pfizer

Completed

A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee

Osteoarthritis, Knee

United States, Canada, Sweden
Regeneron Pharmaceuticals

Completed

Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Centrexion Therapeutics

Completed

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Osteoarthritis of the Knee

United States
Cytonics Corporation

Unknown

APIC-CF Therapy for Mild to Moderate Osteoarthritis of the Knee

Pain | Osteoarthritis

United States
Cubist Pharmaceuticals LLC
Pfizer

Completed

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee

Pain | Osteoarthritis, Knee

United States
Pfizer

Completed

A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis | Chronic Pain

United States
Bausch Health Americas, Inc.

Completed

A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)

Chronic Pain
Labopharm Inc.

Completed

A Four-Arm Study Comparing the Analgesic Efficacy and Safety of Tramadol Once a Day 100, 200 and 300 mg Versus Placebo for the Treatment of Pain Due to Osteoarthritis of the Knee (With 7-Day Follow-up)

Pain
Labopharm Inc.

Completed

An Open-Label Long-term Safety Study of Tramadol HCl OAD (Once A Day) 300 mg in the Treatment of Pain Due to Osteoarthritis of the Knee

Osteoarthritis, Knee
Labopharm Inc.

Completed

A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol HCl / Contramid® Tablets to Twice Daily Tramadol HCl (SR) for the Treatment of Osteoarthritis of the Knee

Pain | Osteoarthritis, Knee
Labopharm Inc.

Completed

A Four-Arm Study Comparing the Analgesic Efficacy and Safety of Tramadol Once a Day 100, 200 and 300 mg Versus Placebo for the Treatment of Pain Due to Osteoarthritis of the Knee

Pain | Osteoarthritis, Knee
Analgesic Solutions
Forest Laboratories

Unknown

Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis

Osteoarthritis

United States
Pfizer

Terminated

A 2 Week Blinded Study For Pain Due To Arthritis Of The Knee

Osteoarthritis

United States
Smerud Medical Research International AS
SantoSolve AS

Unknown

A Study of the Efficacy and Safety of 2PX in Patients With Pain Due to Osteoarthritis of the Knee

Pain | Osteoarthritis

United Kingdom, Finland, Poland, Russian Federation
Sanofi

Completed

TREAD-20: Trial of Hyalgan Three Injection-Regimen for the Treatment of Knee Pain Due to Osteoarthritis

Osteoarthritis

United States
PromoPharma spa

Recruiting

Interventistic Clinical Investigation on the Use of Medical Device in Subjects With Mild-moderate Osteoarticular Pain

Osteoarthritis, Knee

Italy
HALEON

Recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain

United States, Poland
Queen's University
Canadian Institutes of Health Research (CIHR); The Arthritis Society, Canada

Recruiting

Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial

Knee Osteoarthritis | Hip Osteoarthritis

Canada
Riphah International University

Recruiting

Effects of Sensory Motor Training and Kinesthetic Exercises in Knee Osteoarthritis.

Knee Osteoarthritis

Pakistan
Kutahya Health Sciences University

Recruiting

The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis

Pain | Knee Osteoarthritis | Physical Disability

Turkey
Cytonics Corporation
Southern Star Research Pty Ltd.

Not yet recruiting

Evaluation of CYT-108, a Recombinant Protease Inhibitor, for Treatment of Mild to Moderate Primary Osteoarthritis of the Knee

Osteoarthritis | Osteoarthritis, Knee

Australia
Pamukkale University

Recruiting

The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty

Knee Osteoarthritis | Knee Pain Chronic

Turkey
Chinese University of Hong Kong

Not yet recruiting

Pulsed Electromagnetic Field Therapy on Muscle Strength and Function in Patients With End-stage of Knee Osteoarthritis

Knee Osteoarthritis

Hong Kong
Umraniye Education and Research Hospital

Recruiting

Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery

Knee Osteoarthritis

Turkey
University of Nove de Julho

Not yet recruiting

Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA

Osteoarthritis, Knee
Ankara City Hospital Bilkent

Recruiting

Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis

Chronic Knee Osteoarthritis

Turkey
Martina Hansen's Hospital
Oslo University Hospital; South-Eastern Norway Regional Health Authority; Lovisenberg...

Not yet recruiting

Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy

Arthralgia | Osteoarthritis, Knee | Knee Pain Chronic
Dijklander Ziekenhuis

Recruiting

The Effects of Surgical Wait Time for Knee Arthroplasty Quality of Life in Patients Awaiting Knee Arthroplasty (SIT'NWAIT)

Knee Osteoarthritis

Netherlands
University of Lahore

Recruiting

Comparison of Hip Strengthening Exercises and Core Stability Exercises in Patients With Knee Osteoarthritis

Knee Osteoarthritis

Pakistan
University of Texas, El Paso

Recruiting

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

Knee Osteoarthritis | Knee Pain Chronic | Central Pain Syndrome

United States
Dijklander Ziekenhuis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Bravis Hospital

Recruiting

RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA (RADIOPHENOL)

Osteo Arthritis Knee | Knee Pain Chronic

Netherlands
Ahmad Nazari

Not yet recruiting

Evaluation of the Effect of Different Doses of Ozone Therapy on Pain and Function of Patients With Knee Osteoarthritis

Osteo Arthritis Knee
The Hong Kong Polytechnic University
Kwong Wah Hospital

Recruiting

Effect of Structured Exercise in Patients With Knee Osteoarthritis

Osteoarthritis, Knee | Physical Inactivity

Hong Kong
Meltem Meran Çağlar

Not yet recruiting

Investigation of the Effects of Progressive Resistance Exercises in Individuals With Knee Osteoarthritis (OA)

Osteoarthritis, Knee | Biomarkers | Exercise Training
Eli Lilly and Company

Recruiting

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain (CPMP)

Chronic Low-back Pain | Osteoarthritis, Knee | Diabetic Neuropathic Pain

United States, Puerto Rico

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