Search clinical trials for: Pancreatic enzyme insufficiency

Total 63712 results

Ruijin Hospital

Recruiting

The Effect of PERT on Patients Undergoing Pancreaticoduodenectomy

Pancreatic Exocrine Insufficiency | Pancreaticoduodenectomy | Pancreatic Enzyme Replacement Therapy

China
Centro Hospitalar e Universitário de Coimbra, E...
University of Coimbra

Recruiting

Exocrine Pancreatic Insufficiency After Acute Pancreatitis and Pancreatic Enzyme Replacement Therapy

Immunology | Acute Pancreatitis | Exocrine Pancreatic Insufficiency | Gut Microbiota

Portugal
Sunnybrook Health Sciences Centre

Recruiting

PERT to Improve Quality of Life in Patients Undergoing Pancreaticoduodenectomy: A Pilot Randomized Controlled Trial (PERQ-UP)

Pancreatic Insufficiency

Canada
Hospital Clinico Universitario de Santiago

Recruiting

Registry of Pancreatic Exocrine Insufficiency.

Exocrine Pancreatic Insufficiency

Spain
Changhai Hospital

Recruiting

Endotherapy for Painless Chronic Pancreatitis (EACH)

Abdominal Pain | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency | Cholangiopancreatography, Endoscopic Retrograde

China
Seoul National University Hospital

Recruiting

The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral Feeding (PREZENT)

Critically Ill | Enteral Feeding | Exocrine Pancreatic Insufficiency

Korea, Republic of
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Congenital Pure Red Cell Aplasia | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline... and other conditions

United States
Children's Hospital of Philadelphia
Chiesi USA, Inc.

Completed

Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)

Cystic Fibrosis | Pancreatic Insufficiency

United States
The Christie NHS Foundation Trust
Pancreatic Cancer UK

Completed

Pancreatic Cancer Dietary Assessment Study (PanDA)

Pancreas Adenocarcinoma | Pancreatic Neoplasm | Malignant Neoplasm of Pancreas | Well-Differentiated Neuroendocrine Carcinoma

United Kingdom
Azidus Brasil

Withdrawn

Effectiveness of Pancreatic Enzymes in Patients Pancreatic Insufficient: Comparison of Two Drugs

Chronic Renal Failure

Brazil
First Wave Bio, Inc.

Completed

OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis (OPTION)

Cystic Fibrosis (CF) | Exocrine Pancreatic Insufficiency (EPI)

United States, Poland
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Federal Research and Clinical Center of Physical-Chemical...
Moscow State University of Medicine and Dentistry

Completed

Intestinal Microbiota Composition in Patients With Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

Chronic Pancreatitis | Pancreatic Exocrine Insufficiency

Russian Federation
GlycosBio, Inc.
Baylor College of Medicine

Completed

Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
AbbVie
VIVUS LLC; Cystic Fibrosis Foundation; Digestive Care, Inc.; Nestle Health Science

Terminated

Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy)

Fibrosing Colonopathy

United States
Massimo Raimondo, M.D.
Digestive Care, Inc.

Terminated

PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Insufficiency | Pancreatic Enzyme Abnormality

United States
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Shanghai 10th People's Hospital
Tongji Hospital; Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao...

Completed

Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients

Sepsis | Diabetes | Shock | Critical Illness | Acute Renal Failure | Cardiac Arrest

China
Anthera Pharmaceuticals

Completed

EASY: Extended Access to Sollpura Over Years

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Czechia
Anthera Pharmaceuticals

Completed

SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis (SIMPLICITY)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Efficacy and Safety of Ultrase® MT20 in Improving the Coefficient of Fat Absorption (CFA) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Safety and Efficacy Study of Viokase® 16 for the Correction of Steatorrhea

Chronic Pancreatitis | Exocrine Pancreatic Insufficiency | Pancreatectomy

Canada, United States, Poland, Slovakia
Forest Laboratories

Completed

Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Alcresta Therapeutics, Inc.

Completed

Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)

Exocrine Pancreatic Insufficiency

United States
Bristol-Myers Squibb

Completed

Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT) (BENEFIT)

Kidney Transplantation | Chronic Kidney Failure

United States, Argentina, Australia, Germany, Italy, South Africa, Spain, Brazil, Mexico, Belgium, France, Hungary, Switzerland, India, Canada, Austria, Czech Republic, Poland, Israel, Sweden, Turkey
Abbott

Completed

A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Hungary, Spain
Seattle Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Cystic...

Completed

Baby Observational and Nutritional Study (BONUS)

Cystic Fibrosis | Growth Failure | Exocrine Pancreatic Insufficiency

United States
Foundation for Liver Research
Axcan Pharma

Completed

Enzyme Suppletion in Exocrine Pancreatic Dysfunction (SAPES)

Chronic Pancreatitis | Exocrine Pancreatic Insufficiency

Netherlands
Anthera Pharmaceuticals
Cystic Fibrosis Foundation

Completed

Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Pancreatic Insufficiency

United States
Forest Laboratories

Completed

Safety and Efficacy Study of 2 Pancreatic Enzymes for Treatment of Exocrine Pancreatic Insufficiency in Cystic Fibrosis.

Exocrine Pancreatic Insufficiency: Cystic Fibrosis

United Kingdom, Italy, Belgium, Bulgaria, France, Germany, Poland
Digestive Care, Inc.
St. Louis University

Terminated

Bioavailability of Pancreatic Enzymes in the Human Upper Intestine (Duodenum and Jejunum)

Exocrine Pancreatic Insufficiency
University of Oslo School of Pharmacy

Completed

Effects of Cyclosporine A on Pancreatic Insulin Secretion

Chronic Renal Failure

Norway
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Enzyme Activity and Safety of Pancrelipase in Patients With Severe Exocrine Pancreatic Insufficiency (EPI)

Steatorrhea | Pancreatitis | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency
Azidus Brasil

Unknown

Clinical Non-Inferiority of Pancreatic Enzymes (Norzyme ® - Bergamo) Compared To Creon ® (Solvay Pharmaceutical) in Patients With Exocrine Pancreatic Insufficiency

Pancreatic Insufficiency

Brazil
Digestive Care, Inc.

Withdrawn

Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients

Digestive System Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency | Pancreatic Disease

United States
Axcan Pharma
AAIPharma; Mayo Clinical Services; City Hospital Laboratory Birmingham

Completed

An Open-Label Study to Evaluate the Intraduodenal Delivery of Enzymes From Administration of VIOKASE16 in Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency

United States
Hospital Avicenne
Solvay Pharmaceuticals

Completed

Evaluation of the Digestive and Metabolic Utilisation of Dietary Protein in Patients With Chronic Pancreatitis

Chronic Pancreatitis
Ain Shams University

Recruiting

Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients

Chronic Kidney Diseases

Egypt
Cancer Institute and Hospital, Chinese Academy...

Recruiting

NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC

Pancreatic Adenocarcinoma | Advanced Cancer | Drug Use | Capecitabine | Oxaliplatin | First-Line | Cadonilimab | Nanoliposomal Irinotecan

China
Hospital Sirio-Libanes
Daiichi Sankyo

Not yet recruiting

Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE) (VISIONAIRE)

Chronic Kidney Diseases | Atrium; Fibrillation
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
OHSU Knight Cancer Institute
Oregon Health and Science University

Not yet recruiting

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Peking Union Medical College Hospital

Not yet recruiting

Irinotecan Liposome II in Combination With 5-FU/LV and Oxaliplatin in Perioperative Treatment of Borderline Resectable Pancreatic Cancer (undetermined)

Borderline Resectable Pancreatic Cancer
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

HR070803 in Combination With Oxaliplatin, S-1 Versus NALIRIFOX as Adjuvant Therapy for Pancreatic Cancer

Efficacy and Safety
University of Florida

Not yet recruiting

Examining the Impact of High-protein Oral Supplement With Liposomal Curcumin on Inflammation Markers and Oxidative Stress in Adults Undergoing Hemodialysis.

Chronic Kidney Disease 5D
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Ganzhou Hemay Pharmaceutical Co., Ltd

Not yet recruiting

To Evaluate the Pharmacokinetics of Hemay005 Tablets in Patients With Renal Impairment

Psoriasis

Search clinical trials for: Pancreatic enzyme insufficiency

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Georgia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations