Search clinical trials for: Part A: Healthy male volunteers Part B: Mildly overweight, otherwise healthy hypercholesterolemic ma

Total 487369 results

DynPort Vaccine Company LLC, A GDIT Company

Completed

Study to Evaluate the Safety, Tolerability and Immunogenicity of Recombinant Botulinum Vaccine A/B in Healthy Adults

RECOMBINANT BOTULINUM VACCINE A/B

United States
GlaxoSmithKline

Terminated

A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Multiple Sclerosis, Relapsing-Remitting

United Kingdom
Stiefel, a GSK Company

Completed

A Single Dose Phase I Exploratory Study in Healthy Volunteers With GSK2894512 Cream

Dermatitis, Atopic

United States
Washington University School of Medicine

Active, not recruiting

Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal Studies (WeSHARE)

Alzheimer Disease | Dementia of Alzheimer Type

United States
Huahui Health

Completed

A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers

COVID-19

China
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants

Healthy Participants

United States
AbbVie

Completed

Relative Bioavailability of Two Lutikizumab Formulations and Pharmacokinetics, Safety, and Tolerability of Lutikizumab in Chinese Participants

Healthy Volunteers

United States
Brigham and Women's Hospital

Not yet recruiting

Can Food Timing Reduce Your Diabetes Risk?

Dietary Habits

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914

Gonococcal (GC) Infection

United States
Inipharm Australia Pty Ltd

Recruiting

A Study of INI-822 in Healthy Volunteers and Participants With Non-alcoholic Steatohepatitis (NASH) or Presumed NASH

Non-alcoholic Steatohepatitis

Australia
AstraZeneca

Completed

A Study to Assess the Effect of Particle Size of AZD7594 on Pharmacokinetics (PK) After a Single Inhaled Dose When Administered Using the Dry Powder Inhaler in Healthy Volunteers

Asthma, Chronic Obstructive Pulmonary Disease (COPD)

Germany
AceLink Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers

Autosomal Dominant Polycystic Kidney

Australia
Idaho State University

Terminated

Task or Virtual Reality Intervention for Improving UE Function

Upper Extremity Paresis | Hemiplegic Cerebral Palsy | Hemiplegia and/or Hemiparesis Following Stroke

United States
Topokine Therapeutics, Inc.

Completed

Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers

Lipodystrophy | Lipoatrophy | Nasolabial Folds

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate Bioavailability, Food Effect, Safety and Tolerability of a Solid Dosage Formulation of JNJ-54861911 in Healthy Older Male Participants

Healthy

Belgium
Galecto Biotech AB

Completed

A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects

Safety and Tolerability

United Kingdom
International Centre for Diarrhoeal Disease Research...
Newcastle University

Completed

Novel Isotope Dilution Technique to Assess Vitamin A Status

Healthy Infants | Infants With an Inflammatory Condition

Bangladesh
Mandos LLC

Completed

VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, France, New Zealand, Singapore, Spain, Turkey
Indiana University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Cedars-Sinai Medical...

Recruiting

SAMe Trial for Patients With Alcoholic Cirrhosis

Alcoholic Cirrhosis

United States
University of California, Davis
Helen Keller International

Completed

Effect of Small Daily Doses of B-carotene on Breast Milk Retinol

Vitamin A Status

United States
Coopervision, Inc.

Completed

Clinical Evaluation of Two Silicone Hydrogel Contact Lenses

Myopia

United Kingdom
Coopervision, Inc.

Completed

Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers

Myopia | Hyperopia

United States
Coopervision, Inc.
CORE

Completed

Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use

Ametropia

United States, Canada
Mohamad Bydon

Completed

Adipose Stem Cells for Traumatic Spinal Cord Injury (CELLTOP)

Paralysis | Spinal Cord Injuries

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Single Ascending Dose Study of ACT-541468 in Healthy Male Subjects

Healthy Subjects

Netherlands
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers

Malaria

United Kingdom
Yuhan Corporation

Completed

Randomized, Open-label, Parallel Study to Evaluate the Pharmacokinetic Characteristics of Pregabalin According to Different Controlled Released Formulations in Healthy Male Subjects

Healthy

Korea, Republic of
Eli Lilly and Company

Completed

A Study of LY3143753 and LY3185643 in Healthy Participants

Healthy

United Kingdom
Novo Nordisk A/S

Completed

A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People

Healthy Volunteers - Haemophilia A

Germany
Novo Nordisk A/S

Recruiting

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation (ZEUS)

Inflammation | Chronic Kidney Disease | Cardiovascular Risk

Korea, Republic of, Italy, United States, Spain, China, Taiwan, Mexico, Netherlands, Latvia, Malaysia, Thailand, Hungary, Australia, Poland, South Africa, India, Canada, Portugal, Romania, United Kingdom, Bulgaria, Germany, Brazil, Sw... and more
Quidel Corporation

Completed

QuickVue Influenza A + B Test Field Study (QuickVue Flu)

Influenza A, Influenza B

United States
Theravance Biopharma

Completed

TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation

Acute Lung Injury (ALI) Due to Coronavirus Disease-2019 (COVID-19)

United States
Daiichi Sankyo, Inc.

Completed

Food Effects on Milademetan Pharmacokinetics in Healthy Participants

Food Effects on Pharmacokinetics

United States
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Galmed Medical Reserch

Completed

A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers

Healthy

Israel
Coopervision, Inc.
CORE

Completed

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

Astigmatism

United States, Canada
Bristol-Myers Squibb

Completed

Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants

Hepatitis C

United States
Bayer

Completed

A Study to Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Diabetic Nephropathy | Worsening Chronic Heart Failure

Germany
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
Hvivo
Pfizer

Recruiting

Dose, Safety, and Pathogenicity of a New Influenza B Strain

Influenza B

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Janssen Research & Development, LLC

Completed

A Crossover Study to Evaluate the Relative Oral Bioavailability and Food Effect After Single Dose Administration of JNJ-54861911 Tablet in Healthy Elderly Participants

Healthy

Belgium
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
University of Wisconsin, Madison
Quidel Corporation

Completed

Nasal Swab Home Collection Kit (NSHC Kit) Study

Influenza Viral Infections

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Pharmacokinetics and Absolute Bioavailability of GSK962040 Given as an Oral Dose Simultaneously With an Intravenous Microtracer Dose of [14C]-GSK962040 in Healthy Volunteers

Gastroparesis

United Kingdom
Maastricht University Medical Center

Unknown

Repetitive Lipid Intake and Food Intake

Overweight and Obesity | Satiety Response | Satiation

Netherlands
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease

COPD

United Kingdom
University of Miami

Completed

Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia

Episodic Hypoxemia in Mechanically Ventilated Preterm Infants

United States
Bayer
Merck Sharp & Dohme LLC

Completed

A Study in Healthy Adult Male Participants to Learn the Way Vericiguat is Absorbed With and Without Food When Taken as a Single Dose in Liquid Form Suitable for Children Compared to a 10 Milligram (mg) Tablet That Releases the Active Substance Immediately

Heart Failure | Children

Germany
Ferring Pharmaceuticals

Recruiting

A Study Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Persons

Inflammatory Gastrointestinal Diseases

Germany

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