Search clinical trials for: Pathogenic light chains

Total 2723 results

Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis) (LINKER-AL2)

Relapsed/Refractory Systemic Light Chain Amyloidosis
Alfred Chung, MD
AbbVie; Janssen Pharmaceuticals

Recruiting

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

AL Amyloidosis | Light Chain (AL) Amyloidosis | Systemic Light Chain Disease

United States
Francis Corazza

Recruiting

Prognostic Value of Cerebrospinal Fluid Immunoglobulin Free Light Chains in Patients With Multiple Sclerosis

Multiple Sclerosis

Belgium
Hôpital le Vinatier

Recruiting

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease (Nfl_COG)

Schizophrenia | Alzheimer Disease | Bipolar Disorder | FTD

France
University of California, San Francisco

Recruiting

Determining Normal Range for Free Light Chains in Serum Among Twins

Multiple Myeloma

United States
Tulane University School of Medicine

Completed

Effect of Renin-angiotensin-system Blockade on Urinary Free Light Chains in Patients With Type 2 Diabetes Mellitus (UFLC)

Hypertension | Type 2 Diabetes

United States
Ain Shams University

Completed

To Assess the Effect of HDF Versus High Flux Dialysis on Free Light Chains and Cumulative Albumin Loss, in End Stage Renal Disease Patients.

Hemodialysis | End Stage Renal Disease | Hemodiafiltration

Egypt
Oxford University Hospitals NHS Trust
University of Warwick; University of Birmingham; Janssen-Cilag Ltd.; Bloodwise

Completed

Optimising Renal Outcome in Myeloma Renal Failure (OPTIMAL)

Multiple Myeloma | Chronic Kidney Disease

United Kingdom
Centre Hospitalier Universitaire de Nice

Completed

Diagnosic and Pronostic Values of Kappa and Lambda Free Light Chains in Central Nervous System Inflammatory Diseases

Central Nervous System Diseases | Multiple Sclerosis

France
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs (RECORDER)

Complication of Hemodialysis

Italy
Fundación Pública Andaluza para la gestión de la...

Unknown

Prevalence of Amyloidosis in Heart Failure (PREVAMIC) (PREVAMIC)

Heart Failure

Spain
Charlotte Toftmann Hansen

Unknown

Clinical Evaluation of the Serum Free Light Chain Analysis

Multiple Myeloma

Denmark
London Health Sciences Centre
Canadian Institutes of Health Research (CIHR); The Kidney Foundation of Canada

Completed

Trial of Plasma Exchange for Acute Renal Failure at the Onset of Myeloma

Multiple Myeloma | Acute Renal Failure

Canada
Royal Marsden NHS Foundation Trust

Completed

Assessing Free Immunoglobulin Light Chains in Patients With Myeloma

Multiple Myeloma

United Kingdom
Yun-Chen Chang
China Medical University, China

Not yet recruiting

Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients

Breast Cancer | Randomized Controlled Trial | Breast Cancer Female

Taiwan
Universidad de Granada

Not yet recruiting

Impact of Methylxanthine Intake and Blue Light Exposure on Adhesive Shoulder Capsulitis.

Adhesive Capsulitis of Shoulder

Spain
Christin Lang
Department of Sport, Exercise, and Health, University of Basel; University... and other collaborators

Not yet recruiting

Promoting Sleep and Physical Activity Among Adolescent Psychiatric Patients (SLEEPAC)

Insomnia | Mental Disorder in Adolescence | Delayed Sleep-Wake Phase Disorder

Switzerland
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Sleep Disturbance | Long COVID | Long COVID-19
United States Air Force Research Laboratory
Ohio State University; Uniformed Services University of the Health Sciences; The...

Recruiting

Evaluating the Technology and Assessing the Biological Effects of Commercially Available PhotoBioModulation Devices

Physiological Wellness

United States
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol

Sleep Disturbance | Long COVID | Long COVID-19 | Hypersomnia
Northwestern University

Recruiting

ENhancing Exercise With LIGHT to Improve Functioning in PAD (ENLIGHTEN PAD)

Aging | Peripheral Vascular Disease | Peripheral Artery Disease | Walking, Difficulty

United States
Nova Scotia Health Authority

Not yet recruiting

Light Therapy and MRI Imaging for Knee Osteoarthritis Pain

Osteoarthritis, Knee

Canada
Universidade Norte do Paraná

Not yet recruiting

Effects of Photobiomodulation on the Innate Immune System of Neonates and Infants With Bronchiolitis

Bronchiolitis | Virus Disease | Virus

Brazil
Jilin University

Recruiting

White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection

Helicobacter Pylori Infection

China
IR Technology, LLC

Not yet recruiting

Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain

Musculoskeletal Pain | Nociceptive Pain
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Burkitt Lymphoma | Ewing Sarcoma | Neuroblastoma | Diffuse Large B-cell Lymphoma | B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Pembrolizumab in Combination With Investigational Agents in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01B/LIGHTBEAM-U01)

Neoplasm Metastasis
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Yijian Zhu

Recruiting

Platelet-rich Plasma Intradermal Injection Combined With 308 nm Excimer Light for Treating Stable Acral Vitiligo

Vitiligo

China
Université de Sherbrooke

Recruiting

Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users (CycliP)

Dry Eye | Contact Lens Complication

Canada
Technical University of Munich

Not yet recruiting

Light Stimulation to Improve Visual Function After Optic Neuritis in Persons With Multiple Sclerosis (ONSTIM)

Multiple Sclerosis, Relapsing-Remitting | Optic Neuritis
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
Chang Gung Memorial Hospital

Recruiting

The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction

Anterior Cruciate Ligament (Acl) Reconstruction

Taiwan
Musculoskeletal Injury Rehabilitation Research...
The Geneva Foundation; Uniformed Services University (USU) of the Health Sciences and other collaborators

Not yet recruiting

Photomedicine Project 14: PBMT for Performance Enhancement in SOF (SOF)

Low-Level Laser Therapy | Photobiomodulation Therapy | Performance Enhancement | Photomedicine | Quadriceps | Special Operations Readiness
Nanjing University School of Medicine

Recruiting

Daratumumab for Patients With Light Chain Amyloidosis

Light Chain (AL) Amyloidosis

China
Aston University

Not yet recruiting

Photobiomodulation With REd vs BluE Light (REBEL)

Dry Eye Syndromes | Meibomian Gland Dysfunction | Blepharitis

United Kingdom
Centre Hospitalier Universitaire de la Réunion

Recruiting

Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis (ACHROMO-MUCO)

Cystic Fibrosis

Réunion
Zhujiang Hospital

Recruiting

Investigation on the Detection Rate of Pathogenic Viruses in Feces of Parenteral Infected Individuals

Virus Infections

China
Tufts Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

Smoldering Multiple Myeloma

United States
Sciton

Recruiting

Evaluation of Broadband Light Treatment for Solar Lentigines

Solar Lentigo

United States
Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
Icahn School of Medicine at Mount Sinai

Recruiting

A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

Mild Cognitive Impairment | Alzheimer's Disease

United States
University of Nove de Julho

Not yet recruiting

Effect of Photobiomodulation as a Preventive Treatment for Diabetic Foot

Diabetic Foot
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Richard Frye

Not yet recruiting

Safety and Efficacy of tPBM for Epileptiform Activity in Autism (tPBM)

Epilepsy | Neurodevelopmental Disorders | Autism Spectrum Disorder | Neurological Disorder | EEG With Periodic Abnormalities

United States
LumiThera, Inc.

Recruiting

A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (EUROLIGHT) (EUROLIGHT)

Dry Age-related Macular Degeneration

Norway
Ocuphire Pharma, Inc.
Viatris Inc.

Recruiting

Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances (LYNX-2)

Mesopic Vision | Night Vision Loss

United States
Quantel Medical

Recruiting

Prospective Evaluation of Efficacy and Safety of an Intense Pulsed Light Device to Treat Dry Eye Disease"

Dry Eye Disease

United States
Jin Lu, MD

Recruiting

Bortezomib, Pomalidomide, Dexamethasone For Systemic AL Amyloidosis

Systemic Amyloidosis

China
ANRS, Emerging Infectious Diseases

Not yet recruiting

Study Evaluating the Safety, in Terms of HBV Virological Control at 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected With the HIV-1 and HBV Viruses (BI-LIGHT)

HIV Infections | HBV Coinfection

Search clinical trials for: Pathogenic light chains

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