Search clinical trials for: Pharmacokinetic evaluation

Total 32585 results

Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Bio-Thera Solutions

Not yet recruiting

An Evaluation of BAT 8010 for Injection in Combination With BAT 1006 in Locally Advanced or Metastatic Entities Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of the Tumor in Patients Multicenter, Open Phase Ib/IIa Clinical Study

Advanced Solid Tumors
Rovi Pharmaceuticals Laboratories

Recruiting

Evaluation of the Pharmacokinetics, Safety, and Tolerability of IM Letrozole LEBE in Healthy Post-menopausal Women (LEILA-1)

Healthy

Czechia
Transcend Therapeutics

Recruiting

A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects

Post Traumatic Stress Disorder

Australia
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
Alzheimer's Disease Expert Lab (ADEL), Inc.
Oscotec Inc.

Recruiting

A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01

Alzheimer Disease

United States
Chiesi Farmaceutici S.p.A.

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis

United Kingdom
Institut National de la Santé Et de la Recherche...
FUJIFILM Toyama Chemical Co., Ltd.

Recruiting

Evaluation of Tolerance and Pharmacokinetic Profile of High Doses of Favipiravir in Healthy Volunteers (FAVIDOSE)

Infectious Disease | Pharmacology

France
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

BTZ-043 Dose Evaluation in Combination and Selection (DECISION)

Tuberculosis, Pulmonary | Other Specified Pulmonary Tuberculosis

South Africa, Tanzania
Alexion Pharmaceuticals, Inc.

Recruiting

Evaluation of Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants With Generalized Myasthenia Gravis (gMG)

Generalized Myasthenia Gravis | gMG

Spain, Italy, United States, France, Switzerland, Serbia, Japan, Netherlands
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 Tablets

Chronic Hepatitis b

China
Masonic Cancer Center, University of Minnesota

Recruiting

Evaluation of Intravenous Laronidase Pharmacokinetics Before and After Hematopoietic Cell Transplantation in Patients With Mucopolysaccharidosis Type IH.

Mucopolysaccharidosis Type I | Hematopoietic Cell Transplantation

United States
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Safety, Pharmacokinetics and Efficacy of CT-707, Toripalimab and Gemcitabine in Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
Fujian Akeylink Biotechnology Co., Ltd.
The First Hospital of Jilin University

Recruiting

Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets

Pharmacokinetics | Food Affect | Single Ascending Dose | Maximum Applicable Dose

China
LaSanta S A S

Not yet recruiting

Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC

Neoplasms | Vomiting | Cancer Pain | Nausea Post Chemotherapy | Cancer Related Pain

Colombia
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
Weill Medical College of Cornell University

Recruiting

Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate

Testosterone Deficiency

United States
Imperial College London

Recruiting

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting (EHD-Pred PK)

Vasculitis | Asthma | Thyroid Eye Disease | Inflammatory Disease | COPD Exacerbation Acute

United Kingdom
IlDong Pharmaceutical Co Ltd

Recruiting

IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics

Type 2 Diabetes

Germany
Seoul National University Hospital
National Institute of Food and Drug Safety Evaluation (Republic of Korea)

Not yet recruiting

Pharmacokinetic Study of Post-transplant Cyclophosphamide in Pediatric Patients

Hematopoietic Stem Cell Transplantation
Seoul National University Hospital
National Institute of Food and Drug Safety Evaluation (Republic of Korea)

Recruiting

Pharmacokinetic Study of Melphalan in Pediatric Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation

Korea, Republic of
Seoul National University Hospital
National Institute of Food and Drug Safety Evaluation (Republic of Korea)

Recruiting

Pharmacokinetics and Pharmacodynamics of Mycophenolate Mofetil in Pediatric Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation

Korea, Republic of
Seoul National University Hospital
Pharos iBio Co., Ltd.

Recruiting

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PHI 101 for the Treatment of AML

Relapsed or Refractory Acute Myeloid Leukemia

Korea, Republic of
PENTA Foundation
ViiV Healthcare; Hospital Universitario 12 de Octubre; Cromsource; PHPT Foundation

Recruiting

Safety and Pharmacokinetics Evaluation of Fostemsavir + (OBT) in HIV-1 Infected Children and Adolescents Who Are Failing Their cART and Have Dual- or Triple-class Antiretroviral Resistance

HIV Infections With Multi Drug Resistant Virus

United States, South Africa, Mexico, Spain
United BioPharma

Not yet recruiting

Study for Evaluation of the Safety, Pharmacokinetics, and Antiviral Activity of UB-421 Subcutaneous Formulation in HIV Infected Adults

HIV-1-infection
University Medical Center Groningen

Recruiting

Pharmacokinetic Evaluation and Local Tolerability of Dry Powder Amikacin Via the Cyclops™

Tuberculosis

Netherlands
Hospices Civils de Lyon

Recruiting

Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of Hepatotoxicity (Posa-Pk)

Leukemia, Myeloid, Acute

France
Regeneron Pharmaceuticals

Recruiting

Safety and Pharmacokinetics of Cemiplimab Anti-programmed Death-ligand 1 (Anti-PD-1) and Other Agents in Japanese Adult Patients With Advanced Malignancies

Advanced Malignancies

Japan
Groupe Hospitalier Paris Saint Joseph

Recruiting

Evaluation of Pharmacokinetic / Pharmacodynamic and Tolerance Assessment of Dermal Administration of Beta-lactams in the Elderly (BETALACUTANE)

Beta-Lactams | Aged Subject

France
West Virginia University

Recruiting

Prospective Evaluation of Adjusted Body Weight Dosing of Acyclovir in Obesity

Obesity

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

Therapeutic Response Evaluation and Adherence Trial (TREAT) (TREAT)

Anemia, Sickle Cell

United States
AstraZeneca

Completed

AZD7442 Pharmacokinetics, Pharmacodynamics, and Safety Evaluation in Pediatrics (TRUST)

SARS-CoV-2

United States, Belgium, United Kingdom, Brazil, Germany
University of Virginia
University of Florida; Rutgers, The State University of New Jersey

Completed

Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and Adults (PEE-TB)

Tuberculosis

United States
ESM Technologies, LLC
The University of Texas Health Science Center, Houston

Active, not recruiting

Bioavailability Evaluation of curQ+ Curcumin Formulation

Bioavailability

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment

Pain

United States
Vicore Pharma AB
Orphan Reach

Completed

Safety, Efficacy and Pharmacokinetics of C21 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United Kingdom, India, Ukraine, Russian Federation
Kancera AB
LINK Medical Research AB; CRST Oy; Q&Q Labs AB

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Food Effect and Interaction With Midazolam in Healthy Volunteers After Oral Single and Multiple Ascending Dosing of KAND145

Ovarian Cancer

Finland
MediBeacon

Completed

Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the MediBeacon Transdermal GFR Measurement System in Evaluation of Kidney Function in Normal and Renal Compromised Subjects

Chronic Kidney Disease

United States, China
Chiesi Farmaceutici S.p.A.

Active, not recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF

Idiopathic Pulmonary Fibrosis

North Macedonia, Ukraine, United Kingdom
Pliant Therapeutics, Inc.

Completed

Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC)

Primary Sclerosing Cholangitis

United States, Belgium, Australia, Canada, Netherlands, Germany, Austria, United Kingdom, France
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
Fundación Pública Andaluza para la gestión de la...

Completed

Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis

Infectious Endocarditis

Spain
Electra Therapeutics Inc.

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ELA026 in Single and Multiple Doses in Healthy Volunteers

Healthy Volunteers

United States, Austria
Pfizer
Allergan

Terminated

Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

Gram-negative Bacterial Infection

United States, Hungary, Slovakia, Taiwan, India, Estonia, Greece, Italy
Rovi Pharmaceuticals Laboratories

Active, not recruiting

Evaluation of IM Letrozole ISM® Pharmacokinetics, Safety, and Tolerability in Healthy Post-menopausal Women (LISA-1)

Healthy

Czechia
GlaxoSmithKline

Completed

A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)

Pain, Inflammatory

United Kingdom, Germany, Poland
Pfizer

Completed

Evaluation of the Pharmacokinetics, Safety and Tolerability of Single Dose of PF-06480605 in Chinese Healthy Participants

Inflammatory Bowel Disease

China
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants

Pain

Australia
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Pain

United States

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