Search clinical trials for: Pharmacokinetic drug-drug interaction (PK-DDI)

Total 16230 results

Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Abdul Wali Khan University Mardan

Completed

Drug-Drug Interaction Study of Voriconazole With Clarithromycin.

Healthy

Pakistan
Vantia Ltd

Completed

Study in Healthy Male Subjects to Evaluate the Effect of Itraconazole and Rifampicin on the PK of Fedovapagon

Nocturia

Germany
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers

Healthy Volunteer/DDI Study

United Kingdom
The University Clinic of Pulmonary and Allergic...

Unknown

The Role of Clinical Pharmacist in Management of DDIs in CHF Patients

Chronic Heart Failure

Slovenia
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Jiangsu vcare pharmaceutical technology co., LTD

Completed

Pharmacokinetics and Pharmacodynamics of Vicagrel in Healthy Adult Subjects of Different CYP2C19

Healthy Subjects | PK/PD

China
AstraZeneca
IQVIA RDS (Shanghai) Co., Ltd.

Completed

Evaluate the Pharmacokinetics, Safety, and Tolerability of Nirsevimab in Healthy Chinese Adults (PK/ADA)

Evaluate PK Profile

China
Bayer

Completed

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Medical Oncology

United States, Belgium, Spain, France, Netherlands, Australia
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Leumit Health Services

Completed

Clinical and Economic Impact of an Electronic Medical Record Interfaced Decision Support System for Minimizing Severe Drug-Drug Interactions (DDI+)

Healthcare

Israel
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
Spero Therapeutics
Simbec Research; QPS Holdings LLC

Completed

Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741

Healthy Volunteers

United Kingdom
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
Bayer

Completed

Interaction With HIV Antiretroviral Agents

HIV-DDI

United States
MingSight Pharmaceuticals Pty Limited

Completed

A Multiple-Ascending Dose Study of MS-553 in Healthy Volunteers

Safety and PK in Healthy Volunteers

Australia
AryoGen Pharmed Co.

Completed

Pharmacokinetic, Safety and Tolerability Study of Altebrel in Healthy Male Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
Leumit Health Services

Completed

Clinical and Economic Impact of an Electronic Medical Record Interfaced Decision Support System Reinforced With Patient Specific Pharmacogenetic Data for Minimizing Severe Drug-Drug Interactions (DDI+)

Healthcare

Israel
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz

Malaria

United Kingdom
Neurocrine Biosciences

Completed

Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of NBI-98854 in Healthy Subjects

Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects

United States
Drugs for Neglected Diseases
Sanofi

Completed

Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

PK in Healthy Volunteers

France
Astellas Pharma Europe B.V.
FibroGen

Completed

A Study to Evaluate the Dose-proportionality and Effects of FG-4592 in Healthy Young and Elderly Male and Female Subjects

Healthy Subjects | PK for FG-4592

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Amsterdam UMC, location VUmc
UMC Utrecht; Maasstad Hospital; Northwest Clinics Alkmaar

Unknown

Rate Adaptive Atrial Pacing in Heart Failure (ADAPTION)

Heart Failure | ICD | Chronotropic Incompetence

Netherlands
Cinnagen

Completed

A Study Of CinnoRA (Adalimumab-CinnaGen) And Adalimumab (Humira) In Healthy Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
Olympus Surgical Technologies Europe

Withdrawn

Safety and Efficacy of Using PK Morcellator With Pneumoliner Containment Hysterectomy

Gynecologic Surgery
Hadassah Medical Organization

Recruiting

Adjustment of Aminoglycoside Dosing Based on Peak Serum Concentration and Bacterial Minimal Inhibitory Concentration

Aminoglycoside Dosing Based on PK/PD Characteristics

Israel
Boehringer Ingelheim

Completed

DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)

Healthy

Germany
Dr Saara (Ahmad) Muddasir Khan
University of Karachi

Active, not recruiting

Effects of Saffron and Chamomile in Mild to Moderate Depression

Depression

Pakistan
University Ghent
Universidad Complutense de Madrid; Alexianen Zorggroep Tienen

Enrolling by invitation

The Effect of Attention Training on Symptoms and Emotion Regulation in Depressive Patients

Depression

Belgium
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China

Pharmacokinetics

China
Pfizer

Completed

Drug-Drug Interaction Study Of Effect Of PF-03882845 On Simvastatin Pharmacokinetics

Human Volunteers

Singapore
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Malaria

United Kingdom
Smith & Nephew, Inc.

Completed

Safety and Performance of PEEK Anchors (Dynomite, Spyromite, Raptomite) in Extremities

Bunionectomy | Hallux Valgus Repairs | Medial or Lateral Instability Repairs/Reconstructions | Achilles Tendon Repairs/Reconstructions | Midfoot Reconstructions | Metatarsal Ligament/Tendon Repairs/Reconstructions | Scapholunate Ligament Reconstructions | Lateral Epicondylitis Repair | Ulnar | Bicep Tendon...

United States, Canada
GlaxoSmithKline

Completed

GSK239512 DDI Study

Multiple Sclerosis

Australia
Epizyme, Inc.

Completed

Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer

Solid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)

Spain, United States
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom
SK Chemicals Co., Ltd.

Completed

Pharmacokinetic Interaction Study of Dapoxetine 30mg and Mirodenafil 50mg

Drug Interaction Potentiation
SK Chemicals Co., Ltd.

Completed

Pharmacokinetic Interaction Study of Dapoxetine 30mg and Mirodenafil 100mg

Drug Interaction Potentiation
JW Pharmaceutical

Not yet recruiting

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Healthy

Korea, Republic of
Bausch Health Americas, Inc.

Completed

Brodalumab Drug-Drug Interaction (DDI) and Intensive Pharmacodynamic (PK) Study in Psoriasis Subjects

Psoriasis

United States, Australia, New Zealand
Methodist Health System

Recruiting

PK Papyrus Covered Coronary Stent System

Coronary Disease

United States
Smith & Nephew, Inc.

Completed

BIOSURE™ HEALICOIL™ PK Bone In-growth Study

Deficiency of Anterior Cruciate Ligament
NewAmsterdam Pharma
Novum

Recruiting

Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without Obicetrapib

Healthy Volunteers

United States
Pfizer

Completed

Study To Investigate The Potential Drug Drug Interaction (DDI) Between PF-00299804 And Paroxetine In Healthy Subjects

Healthy Volunteers

United States
Children's Hospital of Philadelphia
Ilera Healthcare

Terminated

Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products (Ilera)

Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Parkinson Disease | HIV/AIDS | ALS | Autism Spectrum Disorder | Sickle Cell Disease | Spasticity, Muscle | Huntington Disease | Opioid Use | Neuropathy | Terminal Illness | Inflammatory Bowel Disease (IBD) | Intractable Pain | Ptsd | Dyskinetic Syndrome

United States

Search clinical trials for: Pharmacokinetic drug-drug interaction (PK-DDI)

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