Search clinical trials for: Phase 1, Single-Dose Escalation, Double Blind, Placebo-Controlled, Safety, Tolerability, Pharmacokin

Total 73821 results

Ankara Yildirim Beyazıt University

Recruiting

Investigation of the Effects of Robot Assisted Gait Training With Virtual Reality on Cognitive Functions in Stroke Patients

Stroke | Exoskeleton Device | Locomotion

Turkey
Taiho Pharmaceutical Co., Ltd.

Completed

Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer

Gastric Cancer

Japan
Tianjin Medical University Cancer Institute and...

Recruiting

Study of Neoadjuvant Endocrine Therapy in HR Positive and HER2 Negative Premenopausal Breast Cancer Patients

Breast Cancer

China
University of Liege

Unknown

Light Therapy in Disorders of Consciousness: Behavioral, Neuroimaging and (Neuro)Physiological Assessments.

Disorder of Consciousness
Hasan Kalyoncu University

Recruiting

Study of the Effect of Compassion-Based Education Program Applied to Mothers of Children Diagnosed With Cerebral Palsy

Cerebral Palsy

Turkey
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
Suleyman Demirel University

Recruiting

Developing a New Scale for Evaluating Shoulder Problems

Shoulder Injuries | Shoulder Pain | Shoulder Lesions

Turkey
Sumitomo Pharma Co., Ltd.

Completed

DSP-3025 A Phase 1 Study of Healthy Male Volunteers

Healthy

Japan
Taiho Pharmaceutical Co., Ltd.
UCB Pharma

Completed

Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -

Gastroesophageal Reflux

Japan
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

Secondary Hyperparathyroidism | End-stage Kidney Disease (ESKD)

United States, Bulgaria, Portugal, Spain, Poland, Serbia
Momenta Pharmaceuticals, Inc.

Completed

Assessment of Pharmacokinetics and Safety of M923 Administered Via Auto-injector or Prefilled Syringe, in Healthy Subjects

Healthy

United States, United Kingdom
EZUS-LYON 1

Active, not recruiting

CARdioprotection in Myocardial Infarction (CARIM)

Myocardial Infarct

France
EZUS-LYON 1

Active, not recruiting

The Influence of Manual Therapy Applied to the Cervical Spine in the Prevention of Balance Disorders in the Elderly (ManEq)

Elderly | Gait | Balance, Postural

France
Bristol-Myers Squibb

Completed

Study of the Safety & PK of INX-08189 in Chronically-infected HCV, Treatment-naïve Subjects

HCV (Genotype 1)

United States, Puerto Rico
Ningbo No. 1 Hospital

Recruiting

A New Ligation Using the Double-loop Clips Technique Versus Traditional Techniques in the Treatment of Large Wounds After Endoscopic Resection

Polyps | Closure; Delay

China
Uro-1 Medical

Recruiting

Use of Repris Needle in Bladder Injection

Overactive Bladder Syndrome

United States
Uro-1 Medical

Recruiting

Assessment of VMCore Biopsy Versus Standard of Care Biopsy

Prostate Cancer

United States
Alpha-1 Foundation

Recruiting

Alpha-1 Research Registry

Alpha 1-Antitrypsin Deficiency

United States
Cairo University

Unknown

Clinical Evaluation of Pink Esthetic Score

Thin Gingiva
Calliditas Therapeutics AB

Completed

Study to Evaluate the Pharmacokinetics and Drug-Drug Interactions of Setanaxib in Healthy Adult Male and Female Subjects

Phase 1

France
JKT Biopharma Co., Ltd.

Recruiting

The Safety, Tolerability, Pharmacokinetics and Food Effects of SHEN211 Tablet in Healthy Subjects

Phase 1

China
Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
Eli Lilly and Company

Active, not recruiting

A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese

Overweight

United States
UCB Pharma

Completed

A Randomized, Double-blind, Pharmacokinetics Study to Assess Safety, Tolerability of Levetiracetam 45 Minutes Intravenous Infusion During 4 Days of Bid Dosing in Chinese Healthy Volunteers

Human Volunteers

China
Eastern Mediterranean University

Not yet recruiting

The Effect of Health Education and Yoga on Menopause Symptoms and Quality of Life According to Pender's Model

Quality of Life | Health Education | Yoga | Menopause Symptoms

Cyprus
Eastern Mediterranean University

Not yet recruiting

Effect of Acupressure on Pain, Anxiety and Vital Signs in Patients With Coronary Angiography

Pain | Anxiety | Coronary Angiography | Vital Signs

Cyprus
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
Kitasato University
Yokohama City University Medical Center; St. Marianna University School of... and other collaborators

Unknown

Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension

Hypertension | Type 2 Diabetes Mellitus

Japan
Uro-1 Medical

Not yet recruiting

Evaluation of a Soft Tissue Biopsy System for Trans-rectal and Trans-perineal Biopsy of the Prostate

Prostate Disease
Children's Hospital 1

Recruiting

Sutureless Closure for Primary Total Anomalous Pulmonary Venous Connection (TAPVC)

Total Anomalous Pulmonary Venous Connection | Pulmonary Venous Stenosis | Sutureless Closure

Vietnam
Alpha-1 Foundation

Completed

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD) (PFT)

Chronic Obstructive Pulmonary Disease | Alpha-1 Antitrypsin Deficiency

United States, Puerto Rico
The N.1 Institute for Health (N.1)
Acceset

Completed

A Study Protocol on Peer Digital Acceset (PDA) (PDA)

Mental Health Issue

Singapore
OSCAR Study
Japan Heart Foundation

Completed

OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study

Cardiovascular Diseases | Hypertension

Japan
Eisai Inc.

Completed

Phase 1 Study to Determine the Effect of Lenvatinib (E7080) on the Pharmacokinetics of Midazolam in Subjects With Advanced Solid Tumors

Tumors

United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults

HIV-1

United States, Puerto Rico
University of Southern Denmark
Region of Southern Denmark; Danish Council for Independent Research; The Faculty...

Completed

Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics

Morphine | Organic Cation Transporter 1

Denmark
Eastern Mediterranean University

Not yet recruiting

Acupressure Therapy Method and Heel Blood Effect of Position on Pain and Physiological Parameters

Newborn; Vitality

Cyprus
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Study of Preoperative Docetaxel or Cisplatin (CDDP) + Docetaxel for C-stage IB-II Non-Small Cell Lung Cancer (NSCLC)

Pulmonary Neoplasms

Japan
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Completed

A Trial of Doxorubicin/Cyclophosphamide (AC), Docetaxel (D), and Alternating AC and D for Metastatic Breast Cancer

Breast Cancer | Neoplasm Metastasis

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic Chemotherapy

Chemotherapy-Induced Nausea and Vomiting

Japan
Uwakwe Emmanuel Chijioke

Recruiting

Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour

Duration of Labour

Nigeria
Oxford Brookes University
University of Oxford

Completed

Physical Exercise for Education ('Fit to Study') (FTS)

Physical Activity | Mental Health Wellness 1 | Cognitive Function 1, Social | Academic Attainment | Fitness Testing

United Kingdom
Halozyme Therapeutics

Completed

Randomized, Double-blind, Crossover, Pharmacokinetic (PK) and Glucodynamic (GD) Study of Continuous Subcutaneous Insulin Infusion (CSII) in Participants With Type 1 Diabetes Mellitus (T1DM)

Type 1 Diabetes Mellitus

United States
Cukurova University

Not yet recruiting

Effect of Mobile Application Usage on Drug Compliance After Thyroidectomy

Patient Acceptance of Health Care | Drug Compliance
Astellas Pharma Europe B.V.

Completed

A Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as Fixed-dose Combination Tablets and With Single Individual Tablets of the Same Medications at Three Dose Levels

Healthy Subjects | Bioavailability | Phase 1

Germany
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Losartan and PA21

Drug Interaction Potentiation

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Digoxin and PA21

Drug Interaction Potentiation

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Furosemide and PA21

Healthy

United States
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation

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