Search clinical trials for: Physiological Effects of Drugs

Total 450445 results

Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Head and Neck Squamous Cell Carcinoma

China
Pfizer

Recruiting

A Study About Modified RNA Vaccines Against Influenza in Healthy Adults

Influenza, Human

United States
MedMira Laboratories Inc.

Not yet recruiting

Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario.

Treponema Pallidum

Canada
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

LIROH - Liraglutide for Obesity in HIV (LIROH)

HIV Infections | Obesity

South Africa
Mustafa Burgac

Recruiting

Comparison of Analgesic Efficacy of Serratus Anterior Plan Block and Serratus Posterior Superior Intercostal Plan Block in Breast Surgery

Analgesia

Turkey
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

China
Sohag University

Recruiting

Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery

Hemodynamic Instability and Shivering

Egypt
Beijing Tongren Hospital
The First Affiliated Hospital with Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Reversal of Neuromuscular Blockade

China
Seoul National University Hospital

Not yet recruiting

Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss (Pilot Study)

Hearing Loss, Sensorineural | Hearing Loss, Sudden | Intratympanic Injection
First Affiliated Hospital of Zhejiang University
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML

Myeloid Malignancy | Relapsed/Refractory Acute Myeloid Leukaemia

China
University of Tennessee

Not yet recruiting

Enteral Zinc Supplementation in VLBW Infants

Nutritional Deficiency | Very Low Birth Weight Infant
Hospital de Clinicas de Porto Alegre
Vifor Pharma

Not yet recruiting

IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency (COMBINED-HF)

Heart Failure, Systolic | Iron Deficiencies

Brazil
Sun Yat-sen University

Recruiting

The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites

Malignant Ascites

China
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive

Asthma | Mild Asthma
Roswell Park Cancer Institute

Not yet recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Unresectable Triple-Negative Breast Carcinoma

United States
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
Ruijin Hospital

Not yet recruiting

Effect of Oxycodone on Anxiety State in Painless Abortion

Abortion Complication
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

The Trial of SHR6508 in Secondary Hyperparathyroidism

Secondary Hyperparathyroidism

China
Opna Bio LLC

Not yet recruiting

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
American British Cowdray Medical Center

Not yet recruiting

The Effect of Accompainment by Older Adults on Anesthetic Recovery (AAR)

Old Age; Debility

Mexico
TC Erciyes University

Not yet recruiting

The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction

Middle Ear Disease
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

Systemic Sclerosis | Autoimmune Disorders

United States
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

Sequential Multiple Assignment Randomized Trial for Bipolar Depression (SMART-BD)

Depression | Bipolar I Disorder

United States, Canada
University of Dundee
Juvenile Diabetes Research Foundation; Lexicon Pharmaceuticals

Not yet recruiting

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes (SOPHIST)

Heart Failure | Type 1 Diabetes
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
Peking University Third Hospital
Bayer

Not yet recruiting

Efficacy and Safety of Darolutamide in Combination With Androgen-Deprivation Therapy in Prostate Cancer Patients With Lymph Node-positive After Radical Prostatectomy: A Prospective Observational Cohort Study

Prostate Cancer

China
HealthPartners Institute
United States Department of Defense; Uniformed Services University of the Health...

Not yet recruiting

Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age (INI-CSF-MA)

Healthy

United States
Sun Yat-sen University

Not yet recruiting

Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer

Colorectal Cancer

China
Cerevel Therapeutics, LLC

Not yet recruiting

A Trial to Assess the Absorption, Metabolism, Excretion, and Mass Balance of [14C]-Darigabat After a Single Oral Dose in Healthy Male Participants

Healthy Participants

United States
JW Pharmaceutical

Not yet recruiting

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Healthy

Korea, Republic of
Evon Medics LLC
National Institute on Drug Abuse (NIDA); Howard University; Clinics of Dr. Edwin... and other collaborators

Recruiting

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR)

Methamphetamine-dependence | Opioid Use Disorder | Substance Use Disorders | Alcohol Use Disorder | Cocaine Use Disorder

United States
Johns Hopkins University

Recruiting

Opioid Use After Laparoscopic Salpingectomy

Opioid Use | Post-operative Pain | Sterility, Female

United States
Hospital Universitari Vall d'Hebron Research Institute
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital and other collaborators

Recruiting

Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.

Hepatocellular Carcinoma | Portal Hypertension | Advanced Chronic Liver Disease

Spain
Beijing Anzhen Hospital

Not yet recruiting

Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation (DARE-AF)

Atrial Fibrillation

China
Post Graduate Institute of Medical Education and...
Indian Council of Medical Research

Not yet recruiting

Carvedilol + Simvastatin vs. Carvedilol Alone for Chronic Liver Disease and Cirrhotic Cardiomyopathy and Its Impact on Hepatic Decompensation and Survival; a Double-blind Randomized Controlled Trial (CIRROSTAT)

Decompensated Cirrhosis | Acute Kidney Injury | Cirrhosis, Liver | Left Ventricular Diastolic Dysfunction | Cirrhotic Cardiomyopathy
Shenzhen Institute of Advanced Technology, Chinese...

Recruiting

Variation in the Impact of Coffee on the Metabolic Rate

Healthy

China
Shoaib Rahim
Foundation University Islamabad

Not yet recruiting

Comparison of Post Operative Endodontic Pain in Patients With Irreversible Pulpitis Treated With and Without Dexamethasone.

Pain
Savara Inc.

Not yet recruiting

Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).

Autoimmune Pulmonary Alveolar Proteinosis

United States
Walailak University

Not yet recruiting

Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idiopathic Large Macular Holes (MACROHOLE)

Macular Holes
Hospital San Carlos, Madrid

Recruiting

Efficacy and Safety of Atropine and DIMS Lenses in Controlling Myopia in Children: A Randomized Clinical Trial. (DIMS)

Myopia

Spain
University of Saskatchewan

Recruiting

Three Dimensional Ultrasonographic Detection of Human Ovulation

Ovulation Disorder

Canada
Mahidol University

Not yet recruiting

Role of Ultrasound Guide Greater Occipital Nerve Block at Second Cervical Vertebra in Migraine Headache Prophylaxis

Migraine Disorders

Thailand
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
Institute of Health Information and Statistics...
Institute for Clinical and Experimental Medicine; Brno University Hospital; University... and other collaborators

Recruiting

Early Detection of HCV in Injection Drug Users (EDVIP)

Hepatitis C Virus Infection

Czechia
Children's National Research Institute

Not yet recruiting

Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols

Rhabdomyolysis

United States
Cairo University

Recruiting

Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Perioperative Pain Management

Egypt
Fundación GECP

Not yet recruiting

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free. (ARIAN)

Lung Diseases | Carcinoma, Non-Small-Cell Lung | Resectable Lung Non-Small Cell Carcinoma

Spain
Colgate Palmolive

Not yet recruiting

The Clinical Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlling Established Plaque and Gingivitis

Gingivitis | Plaque, Dental

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Safety and Efficacy of Recombinant Human Thyroid Stimulating Hormone for Adjuvant Diagnosis in Patients With Locally Advanced/Metastatic Differentiated Thyroid Cancer

Recombinant Human Thyroid Stimulating Hormone

China

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