Search clinical trials for: Placebo Controlled

Total 62003 results

Anhui Medical University

Not yet recruiting

A Randomized, Double-blind, Multicenter, Placebo-controlled Trial: the Efficacy of Repetitive Transcranial Magnetic Stimulation With Precision Neuronavigation in Parkinson's Disease

Parkinson Disease | Transcranial Magenetic Stimualtion | Supplementary Motor Area

China
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
G.ST Antivirals GmbH

Recruiting

A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults

Acute Nasopharyngitis

Netherlands
University Hospital, Basel, Switzerland

Not yet recruiting

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure (OLFO-Brain)

Overweight and Obesity

Switzerland
Universidad Nacional de la Matanza

Not yet recruiting

Contextual Factors-Enriched Standard Care on Mechanical Neck Pain

Neck Pain
Qing Ni

Not yet recruiting

Buyuan-zhixiao Formula in the Treatment of Elderly Patients With Diabetes and Multiple Metabolic Disorders

Aging | Diabete Mellitus | Randomized Controlled Trial | Metabolic Disorders | Traditional Chinese Medicine

China
HighTide Biopharma Pty Ltd

Recruiting

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Type 2 Diabetes Mellitus

China
Portal Therapeutics, Inc.

Not yet recruiting

Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants

Healthy Adult Participants

United States
The Second Hospital of Nanjing Medical University

Not yet recruiting

Washed Microbiota Transplantation for Diabetic Gastroparesis

Diabetic Gastroparesis

China
Craig Erickson
Healx Limited

Recruiting

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
Christoph Berger

Not yet recruiting

A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study (MYTHIC)

Community Acquired Pneumonia in Children | Mycoplasma Pneumoniae | Mycoplasma Pneumoniae Pneumonia

Switzerland
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Clinica Universidad de Navarra, Universidad de...

Recruiting

Effect of a Probiotic on Microbiota Associated With the Immune System and Inflammation. (FLORABIOTIC)

Microbiota | Probiotic

Spain
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation Phase I Clinical Study to Assess the Safety, Pharmacokinetics, and Immunogenicity of HLX6018 in Healthy Subjects

IPF
King's College London
King's College Hospital NHS Trust; Imperial College London; Guy's and St Thomas... and other collaborators

Not yet recruiting

Trial of Mirtazapine for Depression in IBD (MDIBD)

Inflammatory Bowel Diseases | Major Depressive Disorder
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Randomized, Double-blind, Placebo-controlled Study of RSS0393 Ointment in Healthy and Psoriatic Subjects

Healthy | Psoriatic Subjects
Shenzhen Hospital of Southern Medical University

Not yet recruiting

Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults

Irritable Bowel Syndrome With Diarrhea | Mental Health Issue | Fecal Microbiota Transplantation

China
University of Ulm

Recruiting

Relative Contribution of Brain Insulin Action for Postprandial Metabolism (BrainInsPPM)

Glucose Metabolism Disorders

Germany
Tiziana Life Sciences LTD

Recruiting

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Secondary Progressive Multiple Sclerosis

United States
King Chulalongkorn Memorial Hospital

Not yet recruiting

Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Cementless Bipolar Hemiarthroplasty - a Randomized Controlled Trial (TXA)

Femoral Neck Fracture | Bipolar Hemiarthroplasty

Thailand
Rajavithi Hospital

Not yet recruiting

Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer With Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial

Weight Gain
University of Ulm

Not yet recruiting

Ultra-high-caloric, Fatty Diet in ALS (LIPCAL-ALS II)

Amyotrophic Lateral Sclerosis

Germany
National Institute on Aging (NIA)

Recruiting

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

Healthy Volunteer

United States
Alnylam Pharmaceuticals

Recruiting

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) (KARDIA-3)

Hypertension | High Cardiovascular Risk

United States
EP Plus Group Sdn Bhd

Not yet recruiting

Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome

Gastrointestinal Diseases | Pathologic Processes | Disease | Irritable Bowel Syndrome | Colonic Diseases, Functional | Digestive System Disease | Intestinal Disease | Colonic Disease

Malaysia
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
University Hospital, Strasbourg, France

Not yet recruiting

a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial (HyperChrono)

Idiopathic Hypersomnia

France
University of Bayreuth
University of Regensburg, Tumor Center Regensburg, Center for Quality Management... and other collaborators

Recruiting

Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients With Lung Cancer (LePaLuMo)

Quality of Life | Lung Cancer

Germany
Children's Oncology Group

Not yet recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Juvenile Myelomonocytic Leukemia
St. Olavs Hospital
Ullevaal University Hospital; Oslo University Hospital; University Hospital of... and other collaborators

Not yet recruiting

Prophylactic Treatment With Atorvastatin for Episodic Migraine. (EStatinMig)

Episodic Migraine
Shanxi Bethune Hospital

Not yet recruiting

JY231(Internal Clinical Drug Code) Injection for the Treatment of Refractory Autoimmune Diseases (JY231、ADs)

Autoimmune Diseases

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Randomized Controlled Study of Immune Checkpoint Maintenance Therapy After Radiotherapy and Chemotherapy for Locally Advanced Head and Neck Tumors Based on Peripheral Blood CD8Tex Detection in Peripheral Blood

Locally Advanced Head and Neck Squamous Cell Carcinoma

China
Fate Therapeutics

Recruiting

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

Advanced Solid Tumor

United States
Palvella Therapeutics, Inc.

Not yet recruiting

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (SELVA)

Microcystic Lymphatic Malformation

United States
M.D. Anderson Cancer Center
KSQ Therapeutics, Inc.

Recruiting

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

Melanoma | Head and Neck Neoplasms | Lung Neoplasms | Advanced Solid Tumor

United States
Fred Hutchinson Cancer Center
PromiCell Therapeutics, Inc.

Not yet recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Marie Badalamente

Recruiting

Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis

Carpometacarpal (CMC) Osteoarthritis

United States
Aarhus University Hospital
University of Aarhus; Central Denmark Region; Vejle Hospital; TrygFonden, Denmark; Aalborg University Hospital and other collaborators

Recruiting

Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder (EDULOX)

Functional Disorder

Denmark
Second Xiangya Hospital of Central South University

Not yet recruiting

A Phase 2, Randomized, Placebo Controlled Study Investigating the Efficacy and Safety of Sorafenib in New-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes
University of Michigan
National Institute on Aging (NIA)

Recruiting

Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Placebo-Controlled Arm (RES)

Parkinsonian Signs in Older Persons

United States
Drug Delivery Company, LLC DBA Akyso Pharmaceuticals
National Institute on Drug Abuse (NIDA); Laboratory Corporation of America; Cognitive...

Not yet recruiting

A Phase 1, Placebo-controlled, Single-Ascending-Dose, Study of BIOPIN 6 in Healthy Adults

Opioid Use Disorder
Capital Medical University

Recruiting

A Prospective, Multicenter, Randomized Controlled Clinical Study on the Efficacy and Safety of Xuanfei Baidu Granule in the Treatment of Influenza A

Influenza A

China
Institute of Hematology & Blood Diseases Hospital...
Henan Cancer Hospital; Tianjin Medical University Second Hospital; The Second... and other collaborators

Recruiting

A Randomized, Double-blind, Placebo-controlled, and Multi-center Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia

Immune Thrombocytopenia | Treatment

China
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
Peking University

Recruiting

Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment

Liver Metastasis Colon Cancer | MSS | ctDNA Genotype | Failed From Standard Treatment

China
Yang Jianjun, PhD

Recruiting

Adebrelimab Combined With SOX Regimen in Preoperative Neoadjuvant Transformation Therapy for Locally Advanced Gastric Adenocarcinoma

Locally Advanced Gastric Adenocarcinoma

China
Shupei Li

Recruiting

A Multicenter, Double-blind, Placebo-randomized Controlled Clinical Study on the Treatment of Non-alcoholic Steatohepatitis With Tibetan Drug Langqing Atar

NASH

China
Changchun GeneScience Pharmaceutical Co., Ltd.
West China Hospital

Not yet recruiting

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease

Systemic Sclerosis Associated Interstitial Lung Disease | Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD) | Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

China
NeuroSense Therapeutics Ltd.

Recruiting

A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease. (RoAD)

Alzheimer Disease

Israel

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