Search clinical trials for: Prior exposure to Leishmania major

Total 475871 results

Nielsen BioSciences, Inc.
U.S. Army Medical Research and Development Command

Completed

Safety, False-Positive Reactions and Sensitizing Properties of Leishmania Tropica Skin Test Antigen

Cutaneous Leishmaniasis

United States
Western University, Canada
Valeo Pharma Inc

Not yet recruiting

Prolonged Hypercoagulability Following Major Liver Resection for Malignancy (PRIORITY)

Thrombosis | Hepatic Disease | Surgery-Complications | Hypercoagulability

Canada
Australasian Leukaemia and Lymphoma Group

Recruiting

A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure. (GOlDiLOX)

Mantle Cell Lymphoma | Mantle Cell Lymphoma Refractory

Australia
VA Office of Research and Development
NYU School of Medicine

Recruiting

Impact of Colchicine on Peri-Operative Major Adverse Cardiovascular Events in Patients With Prior Coronary Revascularization: The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial (POPCORN)

Coronary Artery Disease

United States
Janssen Research & Development, LLC

Recruiting

A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) (VENTURA-LT)

Depressive Disorder, Major

United States, Korea, Republic of, Taiwan, Slovakia, Spain, Bulgaria, Poland, Belgium, Argentina, Czechia, Hungary, South Africa, Sweden, Italy, France, Australia, China, Brazil, Portugal
Janssen Research & Development, LLC

Recruiting

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (VENTURA-1)

Anhedonia | Depressive Disorder, Major

United States, Spain, Bulgaria, Italy, Poland, Belgium, Argentina, Czechia, Hungary, Sweden, Brazil, Australia, Portugal
National University Hospital, Singapore

Recruiting

Phase II Study of FTD/TPI (Lonsurf) in Metastatic Breast Cancers With or Without Prior Exposure to Fluoropyrimidines (LONBRECA)

Breast Cancer

Singapore
Brigham and Women's Hospital

Recruiting

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

Depression | Bipolar Disorder | Bipolar Depression | Major Depressive Episode | Bipolar I Depression | Bipolar II Depression

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Novartis Pharmaceuticals

Active, not recruiting

Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

Ovarian Cancer

United States, Italy, United Kingdom, Malaysia, Taiwan, Turkey, Belgium, Canada, Spain, Singapore, Austria, Denmark, Korea, Republic of, Australia, China, France, Netherlands, Russian Federation, Germany, Argentina, Mexico, Finland, Portuga... and more
Unity Health Toronto
Unity Health Toronto

Completed

Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial (SMILE)

Major Depressive Disorder | Treatment Resistant Depression

Canada
Janssen Research & Development, LLC

Terminated

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Depressive Disorder, Major

United States, Korea, Republic of, Malaysia, Poland, Finland, Chile, Argentina, Slovakia, Ukraine, Denmark
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Division of...

Enrolling by invitation

Improving HIV Prevention Among Heterosexual Cisgender Men Seeking STI Services in Malawi (NJIRA)

HIV Infection | Sexually Transmitted Infections | Pre-exposure Prophylaxis | Systems Navigation

Malawi
Zhejiang Cancer Hospital

Active, not recruiting

A Study to Explore Pamiparib Treatment in Epithelial Ovarian Cancer After Prior PARP Inhibitor Exposure

Epithelial Ovarian Cancer

China
University of York
Medical Research Council; Department for International Development, United...

Completed

A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies (LEISHChallenge)

Leishmaniasis | Cutaneous Leishmaniases | Insect Bites

United Kingdom
Astellas Pharma Inc
Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100

Castration-Resistant Prostate Cancer (CRPC)

United States, Moldova, Republic of, South Africa
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors

Leukemia, Chronic Myelogenous

China
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling

Carcinoma | Cancer

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

Confirmed Diagnosis of ß-thalassemia Major

United States
Janssen Research & Development, LLC

Completed

A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Depressive Disorder, Major

United States
ModernaTX, Inc.

Active, not recruiting

Safety and Immunogenicity of mRNA-1653, a Combined Human Metapneumovirus (hMPV) and Parainfluenza Virus Type 3 (PIV3) Vaccine, in Healthy Adults, and Children 12 to 59 Months of Age With Serologic Evidence of Prior Exposure

Human Metapneumovirus and Human Parainfluenza Infection

United States
AbbVie

Completed

The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone

Major Depressive Disorder

United States, Canada, Czechia, Finland, Poland, Puerto Rico, Serbia, Slovakia
Queen Mary University of London

Completed

Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study (KRATOS)

Quality of Life | Critical Illness | Chronic Kidney Diseases | Acute Kidney Injury | Muscle Loss | Major Trauma

United Kingdom
University of Aarhus

Terminated

Efficacy of Daylight as Adjunctive Treatment in Patients With Depression

Unipolar Depression

Denmark
Soroka University Medical Center

Completed

Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis

Leishmaniasis

Israel
Thomas Jefferson University
Chiesi Farmaceutici S.p.A.

Completed

Buprenorphine Pharmacometric Open Label Research Study of Drug Exposure (B-PHORE)

Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome

United States
Novartis Pharmaceuticals

Withdrawn

Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE) (PEREGRINE)

Age-related Macular Degeneration (AMD)
Shire

Completed

SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder

Major Depressive Disorder

United States
Istituto Clinico Humanitas

Completed

Is the Lack of Prior Exposure to Sperm Antigens Associated With Worse Neonatal and Maternal Outcomes?

Obstetric Complication | Obstructive Azoospermia
Endocyte

Completed

Extension Study of EC145 (Vintafolide) for Subjects Enrolled in a Previous Study With EC145 (MK-8109-010)

Solid Tumors

United States
Takeda

Completed

Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)

Major Depressive Disorder

United States
Stanford University
University of California, San Diego; Takeda; University of Western Ontario, Canada

Terminated

Ulcerative Colitis - Vedolizumab- With/Without Prior Exposure to Anti-TNF（Tumor Necrosis Factor）Therapy

Ulcerative Colitis

United States, Canada
Radboud University Medical Center

Terminated

Influence of an Acidic Beverage on the Imatinib Exposure After Major Gastrectomy (ABILITY)

Gastrointestinal Stromal Tumor | Major Gastrectomy

Netherlands
National Cancer Institute (NCI)

Completed

Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab

Glioblastoma | Brain Neoplasms | Central Nervous System Neoplasms | Glioblastoma Multiforme | Gliosarcoma

United States
University of Minnesota
National Cancer Institute (NCI)

Completed

Effects of Prior Exposure to Conflicting Health Information on Responses to Subsequent Unrelated Health Messages

Communication Research

United States
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder

Depressive Disorder, Major

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)

Depressive Disorder, Major

United States
National Institute of Allergy and Infectious Diseases...

Completed

Surveillance for Leishmaniasis Skin Lesions in Mali

Cutaneous Leishmaniasis

Mali
Major Extremity Trauma Research Consortium
United States Department of Defense

Completed

PRIORITI-MTF Study- Testing Patient Response to the IDEO (PRIORITI-MTF)

Leg Injuries | Trauma

United States
The University of Hong Kong

Completed

Risk of Hepatitis B Reactivation in Patients With Prior HBV Exposure Undergoing Rituximab-containing Chemotherapy: A Prospective Study

Exposure to Hepatitis B Virus

Hong Kong
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Terminated

Phase 2 Study of Nivolumab in Solid Tumors Induced by Prior Radiation Exposure

Solid Tumors Induced by Prior Radiation Exposure

United States
VA Office of Research and Development

Completed

PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) (PTSD/SMI)

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Major Depression | Post Traumatic Stress Disorder

United States
Leibniz-Institut für Wissensmedien

Completed

Confirmation Bias Towards Treatments of Depressive Disorders in Social Tagging

Depression | Depressive Disorder, Major | Depressive Episode | Major Depressive Disorder, Recurrent
U.S. Army Medical Research and Development Command
Walter Reed Army Medical Center

Terminated

Topical Treatment of Recalcitrant Ulcerative Old World Leishmaniasis With WR 279,396

Cutaneous Leishmaniasis

United States
Thomas Jefferson University
Bristol-Myers Squibb

Completed

Apixaban Discontinuation Prior to Major Surgery (ADIOS)

Hemorrhage | Thromboembolism

United States
AbbVie (prior sponsor, Abbott)

Completed

A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects

Solid Tumors

United States
USWM, LLC (dba US WorldMeds)

Completed

Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction

Substance Withdrawal Syndrome | Opiate Dependence | Opiate Addiction

United States
Forest Laboratories

Completed

A One Year Open Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder (MDD)

Major Depressive Disorder

United States

Search clinical trials for: Prior exposure to Leishmania major

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