Search clinical trials for: Programmed Cell Death 1

Total 90300 results

Assiut University

Unknown

Immunohistochemical Assessment of Programmed Death ligand1 and LC3B in GBM

Glioblastoma Multiforme
Merck Sharp & Dohme LLC

Completed

A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)

Mesothelioma

Japan
Merck Sharp & Dohme LLC
Gynecologic Oncology Group; European Network for Gynaecological Oncological...

Active, not recruiting

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Endometrial Neoplasms

United States, Argentina, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Finland, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Mexico, Norway, Poland, Russian Federation, Spain, Sweden, Taiwan, T... and more
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab With or Without Platinum-based Combination Chemotherapy Versus Chemotherapy Alone in Urothelial Carcinoma (MK-3475-361/KEYNOTE-361)

Urothelial Carcinoma Associated 1 RNA, Human
Merck Sharp & Dohme LLC
Novartis Pharmaceuticals

Completed

A Study of the Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022)

Melanoma | Solid Tumors
Ningbo No. 1 Hospital

Recruiting

Conventional Clipping Versus Punching Closure

the Rate of Complete Closure

China
Ningbo No. 1 Hospital

Recruiting

Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical Trial

Bowel Cleansing; Good Taste

China
Ningbo No. 1 Hospital

Not yet recruiting

Effects of Febuxostat for Lowering Uric Acid in NAFLD Patients With Gout

Nonalcoholic Fatty Liver Disease

China
Ningbo No. 1 Hospital

Completed

Pulsed Field Ablation for Paroxysmal Supraventricular Tachycardia（PSVT）

Paroxysmal Supraventricular Tachycardia

China
Ningbo No. 1 Hospital

Unknown

Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

MAFLD-simplified Definition as an Optimized Risk Stratification Tool for Predicting Metabolic Outcomes

Metabolic Associated Fatty Liver Disease
Ningbo No. 1 Hospital

Completed

A Comparison of Bowel Preparation for Colonoscopy Between Digestive Physicians and Non-digestive Physicians

Bowel Preparation

China
University of Yaounde 1

Unknown

The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon (OFA-AFRO)

Surgery | Anesthesia | Clinical Trial | Gynecology | Opioids

Cameroon
Ningbo No. 1 Hospital

Unknown

Reasons for Nonattendance Inpatient Colonoscopy

Inpatient | Colonoscopy Nonattendance

China
University of Oran 1

Completed

Surgical Practices in Algeria : the Cholecystectomy

General Surgery | Cholecystectomy | Practice Guidelines as Topic
Ningbo No. 1 Hospital

Unknown

Effectiveness of Enteral Nutrition for Dose Reduction of Low Dose PEG

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

Second Forward View Examination of Proximal Colon on Adenoma Detection Rate

Colon Adenoma

China
Ningbo No. 1 Hospital

Completed

Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus | Light-to-moderate Alcohol Consumption

China
Ningbo No. 1 Hospital

Completed

The Impact of Experienced Endoscopy Nurse Participation on Polyp and Adenoma Detection During Colonoscopy

Adenoma | Polyp

China
Team Type 1, Inc.

Unknown

Glycemic Response to Road Cycling in Type 1 Diabetes

Type 1 Diabetes
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61) (KEYNOTE-B61)

Renal Cell Carcinoma

Poland, Australia, United States, Canada, France, Hungary, Ireland, Italy, Korea, Republic of, Russian Federation, Spain, Turkey, Ukraine, United Kingdom
Merck Sharp & Dohme LLC

Completed

Biomarkers of Response to Pembrolizumab Combined With Chemotherapy in Non-Small Cell Lung Cancer (KEYNOTE-782, MK-3475-782) (KEYNOTE-782)

Non-Small Cell Lung Cancer

United States, Canada, Hungary, Israel, Spain
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Relapsed Solid Tumor | Refractory Solid Tumor

United States, Canada, France, Australia, Belgium, Germany, Spain, Italy
Eli Lilly and Company

Active, not recruiting

A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Enthesitis Related Arthritis

Spain, Belgium, Germany, Italy, United Kingdom, Denmark, Mexico, Netherlands, Switzerland
Sumitomo Pharma Co., Ltd.

Completed

DSP-3025 A Phase 1 Study of Healthy Male Volunteers

Healthy

Japan
Merck Sharp & Dohme LLC

Recruiting

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

Small Cell Lung Cancer

United States, Australia, Belgium, Bulgaria, Canada, China, France, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Mexico, Portugal, Romania, Russian Federation, Serbia, South Africa, Spain, Turkey, Ukraine, United... and more
King's College London

Completed

MeT4VeT: Mental Health Toolkit for Military Veterans Trial

Mental Health Wellness 1 | Mental Health Issue

United Kingdom
Fundacion para la Investigacion Biomedica del Hospital...
Pfizer

Completed

Effect Of A CCR5 Coreceptor Antagonist On The Latency And Reservoir Of HIV-1

HIV-1

Spain
Taiho Pharmaceutical Co., Ltd.
UCB Pharma

Completed

Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -

Gastroesophageal Reflux

Japan
Merck Sharp & Dohme LLC

Terminated

Efficacy, Safety, and Tolerability of Gebasaxturev (V937) Administered Intravenously or Intratumorally With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants With Advanced/Metastatic Melanoma (V937-011)

Advanced/Metastatic Melanoma

United States, Australia, Chile, France, Germany, Israel, Italy, Korea, Republic of, Norway, South Africa, Spain
Merck Sharp & Dohme LLC

Completed

Relative Bioavailability Study of Subcutaneous Injection Versus Intravenous Infusion of Pembrolizumab (MK-3475) in Participants With Advanced Melanoma (MK-3475-555/KEYNOTE-555)

Melanoma

Australia, South Africa, Spain, Sweden
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Trial of TP Versus TC Regimens for Stage IVb, Persistent, or Recurrent Cervical Cancer (JCOG0505, CC-TPTC-P3)

Uterine Cervical Neoplasms

Japan
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)

Colorectal Carcinoma
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

Secondary Hyperparathyroidism | End-stage Kidney Disease (ESKD)

United States, Bulgaria, Spain, Portugal, Poland, Serbia
Ningbo No. 1 Hospital

Recruiting

Association Between Cardiovascular Diseases and Mental Illness

Cardiovascular Diseases | Mental Disorder

China
Ningbo No. 1 Hospital

Completed

Development and Validation for Predicting Inadequate Bowel Preparation

Colonoscopy | Polyethylene Glycol | Cathartics

China
Ningbo No. 1 Hospital

Completed

Effect of Inadequate Bowel Preparation on Urgent Colonoscopy in Patients With PPB. (PPB)

Bowel Preparation | Post-polypectomy Bleeding | Urgent Colonoscopy

China
University of Oran 1

Completed

Factors Influencing Occurrence Of Hilar Biliary Stricture In Case of Bile Duct Injury

Bile Duct Injury

Algeria
Ningbo No. 1 Hospital

Completed

UEMR vs. CEMR for Diminutive Non-pedunculated Colorectal Polyps

Colonic Polyps

China
Ningbo No. 1 Hospital

Completed

The Impact of Comprehensive Education Before Gastroscopy on Improving the Tolerance of Patients

Comprehensive Education

China
Ningbo No. 1 Hospital

Completed

Comparison of Using Regular or Rotary Polypectomy Snare for the Resection of Colorectal Polyps

Polypectomy Snare

China
University of Yaounde 1

Completed

A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon

Malaria
Lixia Sheng

Not yet recruiting

Clinical Study of OR for Second-line Treatment of Refractory MZL

OR Regimen Refractory Marginal Zone Lymphoma
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC

Small-Cell-Lung Cancer

Japan
Merck Sharp & Dohme LLC

Recruiting

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004)

Non-small Cell Lung Cancer

United States
Izmir Bakircay University

Not yet recruiting

Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery

Quality of Life | Pain, Postoperative | Disability Physical

Turkey
Rambam Health Care Campus
Israel Science Foundation

Completed

Israeli Multi Ethnic Centenarian Project (IMECP)

LONGEVITY 1

Israel
Merck Sharp & Dohme LLC

Completed

A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)

Urothelial Cancer
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy as Neoadjuvant Treatment for Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-173/KEYNOTE-173)

Triple Negative Breast Neoplasms

3

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