Search clinical trials for: Rare Disorders

Total 236579 results

Duke University
American Academy of Neurology

Not yet recruiting

Accelerating TMS for Cervical Dystonia

Isolated Cervical Dystonia

United States
M.D. Anderson Cancer Center
Active Biotech AB

Not yet recruiting

Open Label Phase 2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-Essential Thrombocytosis Myelofibrosis

United States
University Health Network, Toronto

Not yet recruiting

RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders

Irritable Bowel Syndrome | Gastrointestinal Dysfunction | Ehlers-Danlos Syndrome | Hypermobility Syndrome

Canada
Dalian Medical University

Not yet recruiting

Linperlisib Plus Obinutuzumab and Venetoclax for Relapsed and Refractory Blastoid Variant of Mantle Cell Lymphoma.

Mantle Cell Lymphoma

China
Universitätsklinikum Hamburg-Eppendorf
German Federal Ministry of Education and Research

Not yet recruiting

Development and EValuation of an Online Intervention to Reduce Self-Stigma in People With Visible Chronic Skin disEases (DEVISE)

Psoriasis | Atopic Dermatitis | Vitiligo | Hidradenitis Suppurativa | Alopecia Areata

Germany
Sohag University

Recruiting

Treatment of Failed Carpal Tunnel Syndrome by Dorsal Ulnar Artery Perforator Adipofascial Flap

Failed Carpal Tunnel Syndrome Surgery

Egypt
Ruijin Hospital

Not yet recruiting

Cognitive Impairment Cohort Study of the Elderly Population in YuGarden

Neurodegenerative Diseases | Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment

China
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

CAPABLE Transplant

Depression | Quality of Life | End Stage Renal Disease | Disability Physical

United States
IRCCS Burlo Garofolo

Recruiting

Prevalence of Pre-clinical Sjögren Disease and Other Immune Disturbances in Subjects With Autoimmune Thyroiditis Disease

Sjögren | Autoimmune Thyroid Disease

Italy
Caroline Michaela Kistorp
Sanofi

Not yet recruiting

Fibrosis, Inflammation, Oxygenation of Renal Tissue In FabrY Disease (FORTIFY)

Chronic Kidney Diseases | Fabry Disease

Denmark
IRCCS San Raffaele

Not yet recruiting

Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models

Pituitary Adenoma | Acromegaly | Hypopituitarism | Adiposity | Cushing Syndrome | Endocrine Disorders
St. Jude Children's Research Hospital

Not yet recruiting

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

Lymphoma | Hematologic Malignancy | MDS | AML, Childhood | ALL, Childhood

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD) | X-Linked Chronic Granulomatous Disease

United States
Beijing GoBroad Hospital

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Acute Lymphoblastic Leukemia, in Relapse | B-cell Acute Lymphoblastic Leukemia
AstraZeneca

Not yet recruiting

Assessment of Safety of Olaparib in Chinese Patients With Ovarian Cancer in the Real-World Setting

Using NCID Database to Assess the Safety of Olaparib in Chinese Patients With Ovarian Cancer by Examining the Incidence, Seriousness, and Severity of All AE
University of Aarhus
Aarhus University Hospital

Recruiting

Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome (TSCOR_V)

Cardiovascular Diseases | Inflammation | Lymphedema | Turner Syndrome

Denmark
Ataturk University

Recruiting

Comparison of Patients' Postpartum Recovery Using ObsQoR-10 Score in Pregnant Women in Vaginal Delivery With and Without Neuraxial Labor Analgesia

Analgesia

Turkey
King's College Hospital NHS Trust

Not yet recruiting

Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE) (SELF-BREATHE)

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Lung Cancer | Interstitial Lung Disease | Chronic Lung Disease | Dyspnea | Fibrotic Lung Disease

United Kingdom
The University of Queensland

Not yet recruiting

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside (ATNAD)

Ataxia Telangiectasia

Australia
University of South Florida
Center for Smart Use of Technologies to Assess Real-world Outcomes

Not yet recruiting

Effects of Recursive Self-feedback on Speech Production in Aphasia

Stroke | Aphasia
Ragnar Pétur Ólafsson
The Icelandic Centre for Research

Recruiting

Behavioral Activation for Depression and Habitual Rumination (MoodHab)

Major Depressive Disorder

Iceland
Jinling Hospital, China

Recruiting

Study on the Efficacy and Safety of Low-dose CTX as Maintenance Therapy for MM Unsuitable for Transplantation

Newly Diagnosed Multiple Myeloma

China
The Christie NHS Foundation Trust
CellCentric Ltd.

Not yet recruiting

PatIent exPeRiences and prEFerence of trEatment foR Multiple Myeloma (iPREFER)

Multiple Myeloma

United Kingdom
Taichung Veterans General Hospital

Not yet recruiting

ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

Analgesia

Taiwan
Eisai Co., Ltd.

Recruiting

A Post Marketing Study in Participants With Early Alzheimer's Disease Treated With Lecanemab

Alzheimer's Disease

Japan
Biocells (Beijing) Biotech Co.,Ltd

Recruiting

BXOS110 Injection in the Treatment of Acute Ischaemic Stroke

Acute Ischemic Stroke

China
Dr. Sascha Drewlo

Not yet recruiting

Optimization of Cervical Collections in Pregnancy (OCCP)

Fetal Growth Retardation | Preeclampsia | Cervix; Pregnancy | Inherited Genetic Conditions (Diagnosis)
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Spatial Radiogenomics of Ovarian Cancer: Implementation of a Lesion-specific 3D-printed Mould Pipeline in the Clinical Workflow for Image-guided Tissue Multi-sampling of Ovarian Tumours (CO-MOULD)

Ovarian Cancer

Italy
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome (DRIVENT)

Acute Respiratory Distress Syndrome ARDS
H. Lundbeck A/S

Recruiting

A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments (PROCEED)

Migraine

United States
Universidad de Granada

Recruiting

Myofunctional and Respiratory Intervention on Phonation in Stroke

Stroke

Spain
Beijing Tiantan Hospital

Not yet recruiting

Ultrasound-guided Stellate Ganglion Block for Treatment of Chronic Migraine in Adult

Chronic Migraine

China
Leuko Labs, Inc.

Not yet recruiting

Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia (PC002)

Multiple Myeloma | Diffuse Large B Cell Lymphoma
Roswell Park Cancer Institute

Not yet recruiting

MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence

Acute Lymphoblastic Leukemia

United States
Hospital Clinico Universitario de Santiago

Recruiting

Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU (INVIBLADE)

Intubation | Intubation Complication | Intubation; Difficult or Failed | Acute Respiratory Failure | Videolaryngoscopy

Spain
Chinese PLA General Hospital

Recruiting

TCR Reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma

Non-hodgkin Lymphoma

China
University of Freiburg

Not yet recruiting

Spinal CSF Leaks in Chronic Subdural Hematoma (SPICE)

Chronic Subdural Hematoma

Germany
Blueskin AS

Recruiting

A Pilot Cohort Study of Risk Factors and Novel Methods of Skin Lesion Assessments in Adults With Atopic Dermatitis, Alopecia Areata, Psoriasis or Vitiligo (Derma-001)

Psoriasis | Atopic Dermatitis | Vitiligo | Alopecia Areata

Denmark
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
University of Rochester

Not yet recruiting

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Age-Related Macular Degeneration | Retinitis Pigmentosa | Retinal Dystrophies | Alcohol Use Disorder | Stargardt Disease

United States
Ahi Evran University Education and Research Hospital

Recruiting

Investigation of the Efficiency of Radial Extracorporeal Shock Wave Therapy at Different Pulses in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Turkey
Yonsei University

Not yet recruiting

Exploring Approaches With Lower Targets of Blood Pressure and Lipid for Improving Renal Outcome in Advanced Chronic Kidney Disease (EXCELSIOR-CKD)

Hypertension | Chronic Kidney Diseases | Dyslipidemias

Korea, Republic of
Irina Dralyuk
AEvice Health Pte Ltd

Not yet recruiting

AeviceMD for Pediatric Asthma Management (APAM)

Asthma | Asthma in Children | Chronic Respiratory Disease | Pediatric Asthma

United States
Medical College of Wisconsin
Advancing a Healthier Wisconsin Endowment; Food for Health, Inc.

Not yet recruiting

Preventing Obstetric Complications With Dietary Intervention (PLATE)

Preeclampsia | Gestational Diabetes | High Risk Pregnancy | Gestational Hypertension
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Chinese PLA General Hospital

Recruiting

Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL

Non-hodgkin Lymphoma,B Cell

China
University of Calgary
The George Institute for Global Health, Australia

Not yet recruiting

ACT-GLOBAL THROMBOLYSIS (ACT-WHEN-001) Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 (ACT-WHEN)

Acute Ischemic Stroke AIS | Stroke, Acute, Stroke Ischemic | Stroke Acute

Canada, Australia
University Hospital, Grenoble
University Grenoble Alps; Centre National de la Recherche Scientifique, France and other collaborators

Not yet recruiting

Working Memory Functioning in Alzheimer's Disease and Vascular Dementia (MEMTRAV-COG)

Alzheimer Disease | Vascular Dementia | Mixed Dementias
Pär Johansson

Not yet recruiting

Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure (COMBAT-ARF)

Endothelial Dysfunction | Acute Respiratory Failure | Pulmonary Infection

Denmark
Beijing Tiantan Hospital

Not yet recruiting

Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）

TIA | Ischemic Stroke, Acute | Symptomatic Intracranial Artery Stenosis

China

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