Search clinical trials for: Reduce Graft Vs Host Disease

Total 387111 results

Neena Kapoor, M.D.

Not yet recruiting

TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Hematologic Malignancy | Graft Vs Host Disease | Graft-versus-host-disease | Non-hematologic Malignancy
Scripps Translational Science Institute
Cue Health

Recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
University of Liege
University Hospital, Gasthuisberg; University Hospital, Ghent; University Hospital... and other collaborators

Active, not recruiting

Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens

Hematological Malignancies | Graft-Versus-Host Disease

Belgium
Polish Lymphoma Research Group
AstraZeneca

Active, not recruiting

Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) (ACALLO)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Adverse Event | Chronic Graft-versus-host-disease | Response Rate

Poland
Methodist Health System

Enrolling by invitation

Evaluation of the Impact of Reduced Immunosuppression

Graft Vs Host Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Myeloproliferative... and other conditions

United States
Nantes University Hospital

Terminated

Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRIC (CYRIC)

Graft Versus Host Disease

France
Novartis Pharmaceuticals

Completed

A Multicentre, Randomised, Open-label, Controlled, 12-month Follow-up Study to Assess Impact on Renal Function of an Immunosuppression Regimen Based on Tacrolimus Minimisation in Association With Everolimus in de Novo Liver Transplant Recipients. (REDUCE)

Liver Transplant

Spain
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Massachusetts General Hospital; Brigham and...

Completed

Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS

Lymphoma | Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Leukemia | Leukemia, Myeloid | Hodgkin Disease | Leukemia, Myelomonocytic, Chronic | Graft vs Host Disease | Leukemia, Lymphocytic | Lymphoma, Mantle-cell

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis

Primary Myelofibrosis | Secondary Acute Myeloid Leukemia | Secondary Myelofibrosis | Acute Myeloid Leukemia in Remission | Primary Myelofibrosis, Prefibrotic Stage

United States
Tarix Pharmaceuticals

Withdrawn

Efficacy Study of a TXA127 to Reduce Acute Graft-vs-Host Disease in Subjects Undergoing Double Umbilical Cord Blood Transplantation

Hematologic Malignancies

United States
Tarix Pharmaceuticals

Withdrawn

Efficacy Study of a TXA127 to Reduce Graft-vs-Host Disease in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

Hematologic Malignancies

United States
CABYC
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea

Terminated

Alemtuzumab Use (MabCampath®) in Hematopoietic Transplant of Unrelated Donor With Reduced Intensity Conditioning

Graft Versus Host Disease

Spain
Dana-Farber Cancer Institute
Wyeth is now a wholly owned subsidiary of Pfizer; PDL BioPharma, Inc.

Terminated

Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation

Graft-vs-Host Disease

United States
Pavan Reddy, MD

Completed

Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplant

Graft vs Host Disease | Hematologic Malignancies

United States
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors

Leukemia

United States
Sijia Gu

Not yet recruiting

Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Child, Only | Hematopoietic Stem Cell Transplantation | Graft-Versus-Host Disease | Haploidentical Hematopoietic Stem Cell Transplantation

China
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
Xuzhou Medical University

Not yet recruiting

Safety and Efficacy of Treg Cell in the Treatment of GVHD

GVHD
University of Wisconsin, Madison

Not yet recruiting

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Xerostomia | Graft-versus-host-disease | Sjogren's Disease

United States
Incyte Corporation

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study

Acute Graft Versus Host Disease | Acute Kidney Injury | Stem Cell Transplant Complications | Major Adverse Cardiac Events
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT

Ocular Graft-versus-host Disease

Mexico
ReAlta Life Sciences, Inc.

Not yet recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease (AURORA)

Steroid Refractory GVHD
University of Palermo

Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography (SYMILIS OCT)

Oral Disease | Oral Cancer | Actinic Keratoses | Oral Leukoplakia | Oral Squamous Cell Carcinoma | Oral Lichen Planus | Graft-versus-host-disease | Proliferative Verrucous Leukoplakia | Actinic Cheilitis | Oral Potentially Malignant Disorder | Oral Erythroplakia | Oral Lichenoid Lesion

Italy
Anhui Provincial Hospital

Recruiting

A Trial to Evaluate the Safety and Preliminary Efficacy of iMesenchymal Stromal Cells(iMSC) in Subjects With SR-aGVHD

Steroid-refractory Acute Graft-versus-host Disease(SR-aGVHD)

China
Fundación Oftalmológica de Santander Clínica Carlos...
Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud - IDCBIS

Not yet recruiting

Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment (GvHD)

Graft Versus Host Disease
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

Chronic Graft Versus Host Disease

China
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases

Acute Graft-versus-host Disease

China
Anhui Provincial Hospital

Not yet recruiting

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Acute Graft-versus-host Disease

China
University of Seville

Not yet recruiting

Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD

Stem Cell Transplant Complications | Graft-versus-host-disease | Hematological Malignancy | Hematologic Cancer | Graft Versus Host Disease, Chronic

Spain
Mayo Clinic

Not yet recruiting

Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Chronic Graft Versus Host Disease | Hematopoietic and Lymphatic System Neoplasm

United States
Incyte Biosciences Japan GK

Not yet recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
University Hospital, Bordeaux

Not yet recruiting

Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD) (TIL-GVHD)

Chronic Graft Versus Host Disease
Beijing 302 Hospital

Not yet recruiting

Combination of ATG-based Conditioning Regimen and PTCy for GVHD Prevention in Allo-HSCT After PD-1 Blockade

Hematological Malignancies | Graft-versus-host Disease
Stefanie Sarantopoulos, MD, PhD.
National Institutes of Health (NIH); Incyte Corporation; Rigel Pharmaceuticals

Not yet recruiting

Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD

Chronic Graft Versus Host Disease

United States
Ugur Arzu Kulu

Recruiting

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

Endothelial Dysfunction | Graft Versus Host Disease | Acute Myeloid Leukemia, Adult

Turkey
Abbisko Therapeutics Co, Ltd

Recruiting

A Phase II Study Evaluating the Efficacy and Safety of ABSK021 (Pimicotinib)) in the Treatment of cGvHD Chronic Graft Versus Host Disease (cGvHD)

cGvHD

China
Beijing Tide Pharmaceutical Co., Ltd

Not yet recruiting

TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD))

GVHD, Chronic
University of Miami

Recruiting

Horizons Chronic Graft-Versus-Host-Disease Study

Quality of Life | Coping Skills | Graft Vs Host Disease | Stem Cell Transplant Complications

United States
Southwest Hospital, China
Xinqiao Hospital of Chongqing

Recruiting

Treatment of Oral Chronic Graft-versus-host Disease With Human Umbilical Cord Mesenchymal Stem Cell Dressing

Mesenchymal Stem Cells

China
Sanofi

Recruiting

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease. (ROCKnrol-1)

Chronic Graft Versus Host Disease

Australia, Argentina, Belgium, Spain, Sweden, Czechia, United Kingdom, United States, Italy, Germany, Canada, Israel, Denmark, Brazil
The First Affiliated Hospital of Soochow University

Recruiting

Alterations in Intestinal Microbiota, Metabolites, and Immune Cells in Allo-HSCT

Graft Vs Host Disease

China
Institut National de la Santé Et de la Recherche...

Recruiting

Bronchial Epithelium of Children With Post-infectious Bronchiolitis Obliterans (e-PIBO)

Bronchiolitis Obliterans

France
Central Hospital, Nancy, France

Not yet recruiting

Steroids Versus ECP and Steroids as First-line Treatment of Grade II Acute GVHD (COPAVEHDI)

Graft Vs Host Disease

France
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
University of Pisa

Recruiting

Tacrolimus Blood Concentration and Transplant-related Outcomes in Pediatric HSCT Recipients

Graft Vs Host Disease | Stem Cell Transplant Complications | Transplant Failure

Italy

Search clinical trials for: Reduce Graft Vs Host Disease

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