Search clinical trials for: SIERRA

Total 489 results

PATH
Tulane University; Sustainable Health Systems Sierra Leone

Not yet recruiting

A Short Period of Proactive Community Case Management (ProCCM) to Improve Early Care-seeking for Fever in Sierra Leone

Health Services Research
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
Arrowhead Pharmaceuticals

Recruiting

Study of Plozasiran in Adults With Severe Hypertriglyceridemia (SHASTA-4)

Severe Hypertriglyceridemia

United States
Arrowhead Pharmaceuticals

Recruiting

Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia (MUIR-3)

Hypertriglyceridemia

United States
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
Sierra Varona SL
Universidad Europea de Madrid

Not yet recruiting

Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength and Heart Rate Variability

Healthy
EMS

Not yet recruiting

Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (SIERRA)

Allergic Rhinitis
Sierra Varona SL
Universidad Europea de Madrid

Not yet recruiting

Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength, Vertical Jump Performance and Muscle Oxygen Saturation

Healthy
VA Sierra Nevada Health Care System
Merck Sharp & Dohme LLC

Not yet recruiting

Evaluation of PCV15 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans

Immunosuppression | Pneumococcal Vaccines
Sierra Varona SL
Universidad Europea de Madrid

Not yet recruiting

Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength and Heart Rate Variability

Healthy
Sierra Varona SL
Universidad Europea de Madrid

Not yet recruiting

Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity

Healthy
Ocular Therapeutix, Inc.
Duke University; Fortrea

Recruiting

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Doctors with Africa - CUAMM

Recruiting

Pulmonary Edema Resolution in Severe Preeclampsia and Eclampsia (TiPER)

Eclampsia | Severe Pre-eclampsia

Sierra Leone
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Recruiting

Implementation of Out-of-HOspital Administration of the Long-Acting Cabotegravir+Rilpivirine (HOLA)

HIV-1 Infection

Spain
Sierra Varona SL
Universidad Europea de Madrid

Not yet recruiting

Effects of Dry Needling on Vertical Jump Performance

Sports Physical Therapy
Oculis
ICON plc

Recruiting

Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-2)

Diabetic Macular Edema

United States
José Ignacio Recio Rodriguez
Gerencia Regional de Salud de Castilla y Leon; Consejo General de Colegios... and other collaborators

Not yet recruiting

Case Management of Complex Pluripathology in Primary Care (ENGESCC)

Complex and Chronic Pluripathology
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, Germany, Australia, Canada, United Kingdom, Puerto Rico, Bulgaria, Spain
International Vaccine Institute
London School of Hygiene and Tropical Medicine; Karolinska Institutet; Centers...

Not yet recruiting

Global Burden Estimation of Human Papillomavirus (GLOBE-HPV) (HPV)

HPV Infection

Zambia, Bangladesh, Congo, The Democratic Republic of the, Ghana, Nepal, Pakistan, Sierra Leone, Tanzania
Johns Hopkins University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Not yet recruiting

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis (BATON)

Osteonecrosis of the Femoral Head | Avascular Necrosis of the Femoral Head

United States
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD)

United States, Japan, Korea, Republic of, Australia
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

United States, Japan, Korea, Republic of, Australia
University of Minnesota
Innovations for Poverty Action; Peek Vision; Vision Action

Recruiting

Seeing to Learn in Sierra Leone (SLII)

Refractive Errors

Sierra Leone
Cyrano Therapeutics, Inc.

Recruiting

Study of CYR-064 Versus Placebo in Patients.

Hyposmia

United States
Unity Biotechnology, Inc.

Recruiting

Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE) (ASPIRE)

Eye Diseases | Diabetes Mellitus | Retinal Degeneration | Retinal Diseases | Edema | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

United States
London School of Hygiene and Tropical Medicine
University of Ibadan; University of Zimbabwe; University of Malawi; University... and other collaborators

Recruiting

SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities (SUCCEED)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Schizotypal Disorder | Acute and Transient Psychotic Disorder | Other Specified or Unspecified Primary Psychotic Disorder | Bipolar Type I Disorder With Psychotic Symptoms | Bipolar Type II Disorder With Psychotic Symptoms | Single Episode... and other conditions

Malawi, Nigeria, Sierra Leone, Zimbabwe
Washington University School of Medicine
Thrasher Research Fund; Project Peanut Butter; Ministry of Health and Sanitation...

Recruiting

Eggs for Gut Health

Environmental Enteric Dysfunction | Moderate Acute Malnutrition | Stunting | Severe Acute Malnutrition

Sierra Leone
Tulane University
Merck Sharp & Dohme LLC; Kenema Government Hospital

Not yet recruiting

REVIVE (Response to the Ebola Virus Vaccine)

Ebola Virus Disease

Sierra Leone
ViiV Healthcare

Not yet recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy (VOGUE)

HIV Infections | HIV

Spain, Poland, France, Israel, Belgium, Portugal, Germany, Italy, Argentina, Greece, Japan, Ireland, Switzerland, United Kingdom, Denmark, Sweden, Mexico
Fundació d'investigació Sanitària de les Illes...
Andalusian School of Public Health; Fundación Avedis Donabedian; IDIAP JORDI GOL and other collaborators

Not yet recruiting

Effectivenness and Implementation of an Intervention to Improve Primary Care Patient Safety (SinergiAPS-2)

Patient Safety

Spain
Washington University School of Medicine
United States Department of Agriculture (USDA); Project Peanut Butter; Ministry... and other collaborators

Recruiting

Improving Cognition and Gestational Duration With Targeted Nutrition (COGENT)

Postpartum Depression | Preterm Birth | Child Development | Malnutrition in Pregnancy | Antepartum Depression

Sierra Leone
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
University of Michigan
LFR International

Recruiting

Deploying Emergency Bystander Internet Training (DEBIT)

Trauma | Trauma Injury

Kenya, Nigeria, Sierra Leone, Uganda
Exegenesis Bio

Recruiting

A Study of EXG102-031 in Patients With wAMD (Everest)

Neovascular (Wet) Age-related Macular Degeneration (nAMD)

United States
AstraZeneca

Recruiting

Durvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC) (SIERRA)

Advanced Hepatocellular Carcinoma

Korea, Republic of, Italy, Spain, Vietnam, Germany, France, Japan, United States, Hong Kong, Singapore
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Belgium, Australia, Israel, Spain, France, United Kingdom, Denmark, Argentina, Germany, New Zealand, South Africa, Korea, Republic of, Poland, Bulgaria, Canada, Chile, Czechia, Netherlands, Romania, Sweden, Mexico
University of Oxford
Wellcome Trust

Recruiting

Mechanisms of Neurodynamic Treatments (MONET)

Carpal Tunnel Syndrome | Physiotherapy | Neurodynamic Treatment | Nerve Mobilisation | Diffusion MRI | Mechanistic Trial

United Kingdom
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion) (QUASAR)

Macular Edema Secondary to Retinal Vein Occlusion

Japan, Korea, Republic of, China, Israel, Lithuania, United States, Italy, Spain, Hungary, Portugal, Serbia, Poland, United Kingdom, Thailand, Czechia, Austria, Germany, Turkey, Australia, Bulgaria, Estonia, France, Georgia, Latvia, Mal... and more
Aviceda Therapeutics, Inc.

Recruiting

A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) (SIGLEC)

Macular Degeneration | Geographic Atrophy of the Macula

United States
Hospital Costa del Sol

Recruiting

Effectiveness of a Multifactorial Intervention in Frailty Individuals With HIV Infection: HIDRA360 (HIDRA360)

HIV Infections | Frailty Syndrome

Spain
CinDome Pharma, Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Geographic Atrophy

Netherlands, United States, Belgium, Italy, Germany, United Kingdom, Denmark, Spain, Czechia, Switzerland, Turkey, Canada, Hungary, Portugal, Poland, Australia, Sweden
University College Hospital Galway

Recruiting

MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation (MetaMet)

Diabetic Foot | Amputation | Wound Infection | Wound Complication | Wound Healing Delayed | Critical Limb-Threatening Ischaemia | Gangrene; Limb

Ireland
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Mexico, Romania, Brazil, Germany, Argentina, Czechia, Greece, Slovakia
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of RO7434656 in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression (IMAGINATION)

Primary IgA Nephropathy

Korea, Republic of, Australia, Spain, United Kingdom, Taiwan, China, Japan, France, United States, Italy, Greece, Czechia, Singapore, Argentina, Germany, Brazil, Poland, Canada
Complement Therapeutics

Recruiting

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study (i-GAIN)

Eye Diseases | Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease | Macular Atrophy

United Kingdom, United States
University of Colorado, Denver
National Cancer Institute (NCI)

Recruiting

V+PSF-M for Tobacco Cessation in HIV Care in India

Smoking Cessation | Human Immunodeficiency Virus | Smoking, Tobacco

United States, India
University of Pennsylvania
Civil Aerospace Medical Institute

Recruiting

Broadband Sound and Sleep

Noise Exposure

United States

Search clinical trials for: SIERRA

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