Search clinical trials for: Safety of intervention open and laparoscopic

Total 492483 results

Haraldsplass Deaconess Hospital

Unknown

Colon Cancer Prognosis After Radical Surgery

Colon Cancer

Norway
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Fudan University
West China Hospital; Tongji Hospital; Qilu Hospital of Shandong University; Zhejiang... and other collaborators

Recruiting

Laparoscopic Versus Open Pancreatoduodenectomy Following Neoadjuvant Chemotherapy for BRPC

Borderline Resectable Pancreatic Cancer

China
Assiut University

Not yet recruiting

Laparoscopic Versus Open Appendectomy

Chronic Inflammation of Appendix
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Study of Totally Laparoscopic Resection With Natural Orifice Specimen Extraction (NOSE) for Rectosigmoid Cancer

Colorectal Cancer

China
Kevin Boehnke

Active, not recruiting

Open-label Study to Assess the Safety and Efficacy of Psilocybin With Psychotherapy in Adult Participants With Fibromyalgia

Fibromyalgia

United States
Rob Surgical Systems S.L.

Completed

Safety and Performance Assessment of a First Four Arms on Demand Open Robotic Solution for Assisted PN, RN and RP

Nephrectomy | Prostatectomy

Spain
United Therapeutics

Enrolling by invitation

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

Cardiovascular Diseases | Vascular Diseases | Lung Diseases | Hypertension | Connective Tissue Diseases | Pulmonary Arterial Hypertension | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary | Pulmonary Hypertension | PAH | Respiratory Tract Disease

United States, Spain, Australia, Taiwan, Canada, Singapore, United Kingdom, Italy, Germany, China, Mexico, Argentina, Korea, Republic of, Austria, Greece, Sweden, Portugal, Belgium, Brazil, Bulgaria, Chile, Croatia, Czechia, Denmark, Fr... and more
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy and Safety of Ofatumumab in Relapsing Multiple Sclerosis (RMS) Patients in China

Relapsing Multiple Sclerosis

China
CSL Behring

Completed

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome (AEGIS-II)

Acute Coronary Syndrome

United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Croatia, Czechia, Denmark, Estonia, Finland, France, Georgia, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic of, Latvi... and more
Haraldsplass Deaconess Hospital
University of Bergen; Helse-Bergen HF

Active, not recruiting

Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer (D3/CME)

Quality of Life | Complication | Surgical Procedure, Unspecified | Circulating Tumor Cell | Lymph Node Metastases

Norway
ConvaTec Inc.

Completed

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types. (MORGEN)

Pressure Injury | Chronic Ulcer of Leg or Foot

United States
ConvaTec Inc.

Completed

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Performance and Safety of ConvaFoam™ Silicone, ConvaFoam™ Border and ConvaFoam™ Non-Adhesive Dressings in the Management of Surgical and Traumatic Wounds (MATILDA)

Surgical Wound | Trauma-related Wound

United States
San Diego State University
National Institute of Mental Health (NIMH)

Completed

Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)

Suicide

United States
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)

Nonsquamous Non-small Cell Lung Cancer

United States, Argentina, Australia, Canada, Chile, China, France, Germany, Israel, Japan, Korea, Republic of, New Zealand, Poland, Russian Federation, Spain, Turkey, United Kingdom
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Carcinoma, Hepatocellular

Colombia, Israel, Taiwan, United States, Australia, Brazil, Chile, China, Denmark, France, Germany, Hong Kong, Hungary, Ireland, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Norway, Portugal, Puerto Rico, Spain, Thailand, Turke... and more
LILIAN GAO

Active, not recruiting

Randomized, Controlled, Single-blind Exploratory Study of the Efficacy and Safety of Wrist and Ankle Acupuncture Intervention on Nausea, Vomiting and Pain After Sleeve Gastric Surgery in Women

Postoperative Nausea and Vomiting | Laparoscopic Sleeve Gastrectomy

China
Vaxart

Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers ((VXA-G1-1-NN))

Norovirus Infections

United States
R-Pharm
AstraZeneca; Russian Direct Investment Fund; The Gamaleya National Center of...

Completed

Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention

COVID-19

Azerbaijan
Renyi Qin

Completed

Minimally Invasive Versus Open Surgery for PHC

Perihilar Cholangiocarcinoma

China
Pfizer

Completed

An Open-Label Safety Study Of DIC075V (Intravenous Diclofenac Sodium) In Patients With Acute Post-Operative Pain

Pain, Postoperative

United States
Pfizer

Completed

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

Arthritis, Rheumatoid

Hong Kong, United States, Spain, Israel, Finland, Thailand, Turkey, Taiwan, Poland, Czechia, Malaysia, South Africa, Mexico, China, Australia, Slovakia, United Kingdom, New Zealand, Jordan, Canada, Netherlands, Brazil, Colombia, Puerto... and more
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy.

Glaucoma, Open-angle

Slovakia
Gamaleya Research Institute of Epidemiology and...
Russian Direct Investment Fund

Active, not recruiting

An Open Study on the Safety, Tolerability, and Immunogenicity of "Sputnik Light" Vaccine

COVID-19 Prevention

Russian Federation
Pfizer

Terminated

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation (STRIVE)

Staphylococcal Vaccine

United States, Spain, United Kingdom, Canada, France, Japan, Germany, Hungary, Austria, Bulgaria, Sweden
University of California, San Diego
National Institute on Drug Abuse (NIDA); Open Society Foundations; UCSD Center... and other collaborators

Completed

Police Training to Reduce Occupational Needlesticks and HIV Among Substance Users (ESCUDO)

Occupational Needlestick Injuries

Mexico
Johns Hopkins University

Completed

Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery (ORIOLES)

Prostate Cancer | Opioid Use

United States
Bavarian Nordic

Completed

Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection

Smallpox

United States, Puerto Rico
Centre de Recherche de l'Institut Universitaire...

Unknown

Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers

Depressive Disorder | Anxiety Disorders | Stress Disorders, Post-Traumatic | Substance Abuse | Absenteeism | Acute Stress Disorder

Canada
Beijing Friendship Hospital

Unknown

RCT Study on Safety of LPD and OPD in the Treatment of Periampullary Tumors

Death | Complication | Survival | Periampullary Tumor

China
Novartis Pharmaceuticals

Completed

Study to Evaluate Psoriasis Severity and Its Psychosocial Impact Using the Simplified Psoriasis Index (SPI), as Well as Long-term Safety, Tolerability and Efficacy of Secukinumab Administered Subcutaneously in Patients With Moderate to Severe Psoriasis (IPSI-PSO)

Psoriasis

France
Memorial Sloan Kettering Cancer Center

Completed

A Safety Study Assessing the Effects of Receiving Genome Sequencing Results

History of Cancer

United States
UCB BIOSCIENCES, Inc.

Completed

Open-Label Study to Assess Lacosamide Safety as Add-on Therapy for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Epilepsy

United States
Cordis Corporation
Massachusetts General Hospital; Prairie Education and Research Cooperative

Completed

Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System (OPEN)

Cardiovascular Diseases | Peripheral Vascular Disease | Peripheral Artery Disease | Vascular Disease | PAD

United States, Belgium
Baylor College of Medicine
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

An Open-label Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Tourette Syndrome.

Tourette Syndrome
GlaxoSmithKline

Completed

An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010 (AVANDAMETPMS)

Diabetes Mellitus, Type 2
The Medicines Company

Completed

Open-label, Randomized Trial in Participants Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs UFH (BRAVO 2/3)

Transcatheter Aortic Valve Replacement | Aortic Valve Replacement | Severe Aortic Stenosis

Netherlands, Germany, United Kingdom, Canada, France, Italy, Switzerland
Zhejiang University

Completed

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Quality of Life | Complications | Adverse Drug Event | Length of Stay | Hospital Costs

China
GlaxoSmithKline

Completed

Immunogenicity and Safety of Primary and Booster Vaccination With DTPa-HBV-IPV/Hib Vaccine

Hepatitis B
Biotronik AG

Unknown

BIOFLOW-III All-comers Orsiro Safety and Performance Registry (BIOFLOW-III)

Myocardial Ischemia | Coronary Artery Disease

Germany, Latvia, Spain, Netherlands, Italy, Austria, Chile, Denmark, France, Portugal, Sweden, Switzerland, United Kingdom
Cedar, United Kingdom
National Institute for Health and Care Excellence (NICE); British Society of... and other collaborators

Unknown

ROPE Registry Project to Determine the Safety and Efficacy of Prostate Artery Embolisation (PAE) for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Enlargement (LUTS BPE). (UKROPE)

Transurethral Resection of the Prostate (TURP) | Lower Urinary Tract Symptoms Caused by Benign Prostatic Enlargement (LUTS BPE) | Prostate Artery Embolisation (PAE) | Open Prostatectomy | Laser Enucleation or Ablation of the Prostate
Central Hospital, Nancy, France

Completed

Medical Economic Evaluation and of Quality of Life of the Kidney Living Donors. (DOVIREIN)

Kidney Transplantation

France
Andromeda Biotech Ltd.

Terminated

Open-Label Extension Study to Evaluate Long Term Safety and Treatment Effect of DiaPep277® (DIA-AID 2)

Type 1 Diabetes

United States
Novartis Vaccines

Completed

A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Children Aged 2 to 10 Years

Meningococcal Disease | Meningococcal Meningitis

Spain, Brazil, Hungary, Peru
Desitin Arzneimittel GmbH

Completed

PIRLONG-PD Safety and Efficacy of Piribedil in Parkinson's Disease During Long Term Therapy (PIR-008/K)

Parkinson's Disease

Germany
Novartis Vaccines

Completed

Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Healthy

United Kingdom
Shuguo Zheng, MD

Completed

Laparoscopic Hepatectomy Versus Open Hepatectomy for PHC

Primary Liver Carcinoma

China
Second Affiliated Hospital of Xi'an Jiaotong University

Unknown

Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial

Liver Cirrhosis | Portal Hypertension

China
Kantonsspital Aarau

Completed

Clinical Trial Comparing Conventional and Robot-assisted(Da Vinci®)Laparoscopic Interventions for Hysterectomy

Postoperative Complications | Intraoperative Complications | Laparoscopic Technique no Switch to Open | Duration of Surgery

Switzerland
Novartis
Novartis Vaccines

Completed

A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults

Japanese Encephalitis | Rabies | Yellow Fever | Meningococcal Disease | Typhoid | Meningococcal Meningitis

Czech Republic, Germany

Search clinical trials for: Safety of intervention open and laparoscopic

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