Search clinical trials for: Salivary Hypofunction

Total 1331 results

MeiraGTx, LLC
National Institute of Dental and Craniofacial Research (NIDCR)

Active, not recruiting

Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

Squamous Cell Head and Neck Cancer | Radiation Induced Xerostomia | Salivary Hypofunction

United States
MeiraGTx UK II Ltd

Completed

A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia

Head and Neck Cancer | Radiation-Induced Parotid Gland Hypofunction | Xerostomia Due to Radiotherapy

United States, Canada
National Institute of Dental and Craniofacial Research...

Completed

Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer

Parotid Salivary Dysfunction

United States
Universidad Autonoma de Nuevo Leon

Unknown

Treatment of Salivary Gland Hypofunction With Neuro- Electrostimulation (SALELECTROSTIM)

Xerostomia | Sjögren's Syndrome | Polypharmacy

Mexico
Samsung Medical Center

Completed

Prevalence of Salivary Hypofunction in Patients With Globus Pharyngeus

Globus Pharyngeus

Korea, Republic of
Karamanoğlu Mehmetbey University

Not yet recruiting

Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease

Periodontitis | Periodontal Diseases
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases (BAH247)

Autoimmune Diseases | Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Lupus Erythematosus Acute

China
The Christie NHS Foundation Trust
Royal Marsden NHS Foundation Trust; University College London Hospitals

Not yet recruiting

Investigating the Role of Adjuvant Proton Beam Therapy in Patients With Parotid Carcinoma (PRONTO)

Parotid Cancer
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
University of Udine

Recruiting

Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy (ENDOmiRNA)

Endometriosis

Italy
Ain Shams University

Recruiting

Management of Radiotherapy-related Xerostomia With Green Tea and Peppermint

Radiation-induced Xerostomia

Egypt
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Not yet recruiting

Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Immune Thrombocytopenia | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Primary Biliary Cholangitis
Ain Shams University

Recruiting

The Efficacy of Hibiscus Sabdariffa in Xerostomia

Radiation-induced Xerostomia

Egypt
Changhua Christian Hospital

Not yet recruiting

The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube

Endotracheal Tube | Thirst | Dry Mouth

Taiwan
Peking Union Medical College Hospital
Shengjing Hospital; The Affiliated Hospital of Qingdao University; Children's... and other collaborators

Recruiting

Belimumab After Rituximab in Resistant Primary Juvenile SS (BRRPJS)

Pediatric ALL | Sjogren's Syndrome

China
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
Kahramanmaras Sutcu Imam University

Not yet recruiting

Evaluation of Biopsychosocial Features, Pain, Fatigue, Quality of Life, Swallowing, and Disease-Specific Symptoms in Patients With Primer Sjogren's Syndrome

Sjogren's Syndrome

Turkey
Dompé Farmaceutici S.p.A

Recruiting

Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye (GEMINAE)

Dry Eye | Sjögren Syndrome

United States
Chang Gung Memorial Hospital

Recruiting

Salivary Conductivity Screening for Primary Sjögren's Syndrome

Dry Eye Syndromes | Sjogren's Syndrome

Taiwan
Izmir Katip Celebi University

Recruiting

Evaluation of Salivary Galectin-8, Galectin-9 and RANKL Levels of Individuals With Different Periodontal Diseases

Periodontal Diseases

Turkey
Kahramanmaras Sutcu Imam University

Not yet recruiting

Reliability, Validity, and Responsiveness of the Turkish Version of Eating Assessment Tool-10 for Patients With Primer Sjögren's Syndrome

Sjogren's Syndrome
Izmir Katip Celebi University

Recruiting

Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases

Periodontal Diseases

Turkey
Kahramanmaras Sutcu Imam University

Recruiting

Investigation of the Effectiveness of Cognitive Exercise Therapy Approach in Patients With Primary Sjögren's Syndrome

Primer Sjogren's Syndrome

Turkey
ZIWIG
Monitoring Force Group

Not yet recruiting

Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology (GynRNA)

Cervical Cancer | Gynecologic Cancer | Endometriosis | Ovarian Cancer | Uterine Cancer | Fibroid | Gynecologic Disease | Cyst Ovary

France
Fudan University

Recruiting

The Study on the Mechanism of Radiotherapy-elicited Immune Response

Radiotherapy | Esophageal Carcinoma Salivary Gland Type

China
University of Wisconsin, Madison

Not yet recruiting

Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia

Xerostomia | Graft-versus-host-disease | Sjogren's Disease

United States
China Immunotech (Beijing) Biotechnology Co., Ltd.
Shanghai Changzheng Hospital

Not yet recruiting

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

Systemic Lupus Erythematosus | Systemic Sclerosis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Antiphospholipid Syndrome | Inflammatory Myopathy
Shanghai Changzheng Hospital

Recruiting

Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Universidad Católica de Cuenca

Recruiting

Effect of Xylitol-based Chewing Gums, Sugar-free and Sugared, on Salivary Flow and pH in Young Adults

Healthy

Ecuador
Babujinaya Cela

Not yet recruiting

Effect of Stellate Ganglion Block on Drooling in Parkinson's Syndrome

Parkinson's Syndrome
Johns Hopkins University

Not yet recruiting

Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye (IIR)

Dry Eye | Neurotrophic Keratitis | Sjogren's Syndrome

United States
Tufts University
Colgate Palmolive

Not yet recruiting

Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine

Xerostomia

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Recruiting

Early Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Systemic Lupus Erythematosus | Systemic Sclerosis | Idiopathic Inflammatory Myopathies | Primary Sjögren Syndrome | IgG4 Related Disease

China
Sultan Besiktas

Not yet recruiting

Massage for Newborns Receiving Nasal CPAP

Stress | Newborn | Massage | Comfort
Cairo University

Not yet recruiting

Prevalence Of Non-Carious Cervical Lesions, Associated Risk Indicators and Salivary Assessment Among Middle Adulthood Patients.

Non-carious Cervical Lesions

Egypt
Ege University
THE SCIENTIFIC AND TECHNOLOGICAL RESEARCH COUNCIL OF TÜRKİYE

Recruiting

Comparison of Salivary Procalcitonin (PCT) Levels and Serum PCT Levels

Bacterial Infections | Children, Only | Procalcitonin | Saliva

Turkey
Hacettepe University

Not yet recruiting

Oral Structural and Functional Problems in Children With Autism

Autism Spectrum Disorder | Chewing Problem | Drooling
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
Peking University First Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.; Beijing Biote Pharmaceutical Co.,Ltd

Recruiting

Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma

Salivary Gland Neoplasm Duct

China
University of Pisa

Recruiting

Ultra-High Frequency Ultrasonography in Sjögren's Syndrome (UltraSjögren)

Sjogren's Syndrome

Italy
University of Central Florida

Recruiting

Rheumatology Diet Study

Autoimmune Diseases | Rheumatoid Arthritis | Fibromyalgia | Psoriatic Arthritis | Sjogren's Syndrome | Diet Habit | Ankylosing Spondylitis | Scleroderma | Rheumatologic Disease | Systemic Lupus Erythematous | Dermatomyositis/Polymyositis

United States
Medipol University

Recruiting

Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients

Vertigo | Vestibular Diseases | Vestibular Vertigo

Turkey
Liaoning Chengda Biotechnology CO., LTD

Recruiting

Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR)

Japanese Encephalitis | Measles | Rubella | Mumps

China
University of Belgrade

Recruiting

Salivary Signal Molecules for Neural and Vascular Homeostasis in T2DM

Type 2 Diabetes

Serbia
IRCCS Burlo Garofolo

Recruiting

Prevalence of Pre-clinical Sjögren Disease and Other Immune Disturbances in Subjects With Autoimmune Thyroiditis Disease

Sjögren | Autoimmune Thyroid Disease

Italy
Centre Hospitalier Universitaire de Nice

Recruiting

Ro60 Expression in Macrophages in Sjogren's Disease (RoMioSS)

Sjogren's Syndrome

France
University Tunis El Manar

Not yet recruiting

EVADRY® in the Treatment of Xerostomia in Sjögren's Syndrome (DRYLESS)

Sjogren's Syndrome
Amgen

Recruiting

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Sjogren's Syndrome

United States
Riphah International University

Recruiting

Comparative Effects Of Gaze Stability Exercises And Optokinetic Exercises In Patients With Vestibular Hypofunction

Vestibular Disorder

Pakistan
Riphah International University

Recruiting

Transcutaneous Auricular Vagus Nerve Stimulation on Dizziness & Balance in Elderly Population

Vestibular Hypofunction

Pakistan

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