Search clinical trials for: Serine Proteinase Inhibitors

Total 64213 results

Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Hospital Sirio-Libanes
Daiichi Sankyo

Not yet recruiting

Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE) (VISIONAIRE)

Chronic Kidney Diseases | Atrium; Fibrillation
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Guangdong Provincial People's Hospital

Not yet recruiting

PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

Colorectal Cancer
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Peking Union Medical College Hospital
Peking University; Shanghai Huilun Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS (STAR)

Acute Respiratory Distress Syndrome

China
International Bio service

Not yet recruiting

Bioequivalence Study of Apixaban 5 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
Duke University
Regeneron Pharmaceuticals

Not yet recruiting

TOP 2301: Neoadjuvant Chemo for NSCLC

Non Small Cell Lung Cancer
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Shen Lei

Not yet recruiting

Comparison of Nafamostat and Unfractionated Heparin in RRT for Sepsis Associated AKI

Sepsis

China
Nanfang Hospital, Southern Medical University

Not yet recruiting

A Clinical Study on the Efficacy and Safety of ABCD in the Treatment of Patients With Invasive Fungal Disease

Invasive Fungal Disease
VarmX B.V.

Recruiting

Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant

Coagulation Disorder

Netherlands
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Recruiting

Rivaroxaban for Intracardiac Thrombosis in the Pediatric Population

Intracardiac Thrombus

Italy
Queen Mary University of London

Not yet recruiting

Thromboprophylaxis in Lower Limb Immobilisation (TiLLI)

Thrombosis | Injury Leg
Beijing Luhe Hospital

Recruiting

Effects of PCSK-9 Inhibitor Treatment Prior to Undergoing Primary Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction

STEMI

China
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Ruijin Hospital; China-Japan Friendship...

Recruiting

The Study of Monitoring and Dosing Guidance of Direct Oral Anticoagulants Based on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics

Pulmonary Embolism

China
Peking University Third Hospital

Recruiting

Effect of Oral D-mannose Tablets on Pharmacokinetics of Dabigatranate in Healthy Adults

Health

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Angiotensin II Injection Versus Placebo in Patients With Refractory Distributed Shock

Vasodilatory Shock

China
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Walton Centre NHS Foundation Trust
University of Liverpool; National Institute for Health Research, United Kingdom

Not yet recruiting

Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage (RESTARTtlCrH)

Traumatic Intracranial Haemorrhage
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
M.D. Anderson Cancer Center
Bristol-Myers Squibb; United States Department of Defense; Cancer Prevention...

Not yet recruiting

A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC)

Metastatic Renal Cell Carcinoma

United States
Azienda Ospedaliero Universitaria Maggiore della...

Recruiting

EdOxaban in fRagIle Patients With Percutaneous Endoscopic GAstrostoMy and atrIal fIbrIllation (ORIGAMI II)

Atrial Fibrillation | Fragility

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Heart Failure | Mitral Regurgitation

China
Bayer
Janssen Pharmaceutical Companies (formerly Johnson & Johnson Pharmaceutical...

Recruiting

An Observational Study to Learn More About How Safe Treatment With Rivaroxaban is in Children in Japan With Venous Thromboembolism

Venous Thromboembolism

Japan
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial.

Cardiac Disease
Xiaotong Hou

Not yet recruiting

Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation

Extracorporeal Membrane Oxygenation Complication

China
Xiaotong Hou

Not yet recruiting

Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO

Extracorporeal Membrane Oxygenation Complication

China
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
Hôpital NOVO

Recruiting

Assessment of a Procedure for Managing Oral Anticoagulants (NACO) in the Management of Fractures (STOP-NACO)

Femur Fracture

France
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of SHR-2004 Injection in Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery

Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery
Seoul National University Hospital
Medtronic Korea Co., Ltd.; Samjin Pharmaceutical Co., Ltd.

Recruiting

Pill-in-the-POCKET Oral Anticoagulation Strategy After AF Catheter Ablation (POCKET-OAC)

Atrial Fibrillation

Korea, Republic of
Nanfang Hospital, Southern Medical University

Recruiting

Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients

Glioma, Malignant

China
University Hospital, Angers

Not yet recruiting

RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing (RIVACAST)

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism | Thromboprophylaxis | Lower Limb Trauma | Immobilisation

France
Nanjing Medical University
Beijing Anzhen Hospital

Not yet recruiting

Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Sivelestat) VI

Systemic Inflammatory Response Syndrome | Aortic Dissection

China
Bayer
Janssen Research & Development, LLC

Not yet recruiting

An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure

Children | Congenital Heart Disease | Prevention of Venous Thromboembolism | Fontan Procedure

Japan
Korea University Anam Hospital

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation (REVISE-AF)

Atrial Fibrillation | Anticoagulant Adverse Reaction

Korea, Republic of
Anna Stanhewicz, PhD

Recruiting

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia

Preeclampsia

United States
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Evaluate the Efficacy and Safety of Edoxaban on Prevention of Catheter-related Thrombosis (CRT) in Cancer Patients (Thrombosis)

Cancer | Catheter Complications | Thrombosis, Venous

China
Talphera, Inc

Not yet recruiting

Nafamostat Efficacy in Phase 3 Registrational CRRT Study (NEPHRO)

Acute Kidney Injury
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

Hemophilia A

Taiwan
National Taiwan University Hospital

Recruiting

Evaluataion of NOAC Levels in Acute Stroke

Ischemic Stroke | Anticoagulant Adverse Reaction

Taiwan
Region Stockholm
Amgen

Not yet recruiting

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Acute Metabolic Effects of Evolocumab and Atorvastatin
Xuanwu Hospital, Beijing

Not yet recruiting

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke
Kingman Regional Medical Center
La Jolla Pharmaceutical Company

Recruiting

Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock

Sepsis | Systemic Inflammatory Response Syndrome | Shock | Septic Shock

United States
Basma Rabiey

Not yet recruiting

Comparison Between Haparin and Herodin in HD

Haemodialysis
China National Center for Cardiovascular Diseases

Not yet recruiting

Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation

Stroke | Atrial Fibrillation | Major Adverse Cardiac Events | Anticoagulant Adverse Reaction

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