Search clinical trials for: Subjects with active Crohn's disease

Total 412139 results

Abivax S.A.

Not yet recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease (ENHANCE-CD)

Moderately to Severely Active Crohn Disease
AbbVie

Not yet recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Prometheus Biosciences, Inc., a subsidiary of Merck...

Active, not recruiting

A Phase 2a Safety and Efficacy Open-Label Study of PRA023 in Subjects With Moderately to Severely Active Crohn's Disease (APOLLO-CD)

Crohn Disease

United States, Australia, Belgium, Canada, Czechia, France, Georgia, Poland
AbbVie

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy

Crohn's Disease
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Study of Ustekinumab in Pediatric Subjects With Moderately to Severely Active Crohn's Disease (STELARA)

Crohn Disease

United States, Belgium, Canada, France, Poland, Germany
Provention Bio, Inc.

Completed

Phase 2a Study of PRV-6527 in Subjects With Moderately to Severely Active Crohn's Disease (PRINCE)

Crohn's Disease

Austria, Germany, Hungary, Poland, Russian Federation, Spain, Ukraine
Shire

Completed

Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease

Crohn's Disease

United States, Canada
Shire

Completed

Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008

Crohn's Disease

United States, Canada
Medtronic - MITG

Completed

Clinical Study Comparing PillCam® Crohn's Capsule Endoscopy to Ileocolonoscopy (IC) Plus MRE for Detection of Active CD in the Small Bowel and Colon in Subjects With Known CD and Mucosal Disease. (BLINK)

Crohn Disease

United States, Israel, Austria
UCB Biopharma S.P.R.L.

Completed

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Moderate and Severe Active Rheumatoid Arthritis | Active Psoriatic Arthritis | Active Ankylosing Spondylitis | Moderately to Severely Active Crohn's Disease

United States
Celgene

Terminated

Efficacy and Safety Study of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease

Crohn Disease

United States, Korea, Republic of, Netherlands, Spain, Belgium, Denmark, Australia, Austria, Russian Federation, United Kingdom, Croatia, Canada, Italy, Hungary, Israel, Portugal, Serbia, Poland, Germany, France, Czechia, Greece, Sl... and more
Medtronic - MITG

Completed

PillCam® Platform With the PillCam Crohn's Disease Capsule

Crohn's Disease

United States
Celgene

Terminated

A Long-term Active Treatment Study of Mongersen (GED-0301) in Subjects With Crohn's Disease

Crohn's Disease

United States, Korea, Republic of, Spain, Netherlands, Belgium, Australia, Austria, Denmark, United Kingdom, Hungary, Israel, Portugal, Canada, Germany, Italy, Croatia, Czechia, Greece, Russian Federation, Serbia, Slovakia, Ukraine, Polan... and more
Celgene

Completed

A Randomized, Double-blind, Study to Explore the Effect of GED-0301 in Subjects With Active Crohn's Disease

Crohn Disease

United States, Australia, Canada, Slovakia, Hungary
GlaxoSmithKline

Terminated

An Active Treatment Study to Induce Clinical Response and/or Remission With GSK1605786A in Subjects With Crohn's Disease (SHIELD-4)

Crohn's Disease

United States, France, Netherlands, Spain, Taiwan, Bulgaria, Germany, Poland, Ukraine, Belgium, Israel, Korea, Republic of, Australia, Austria, Canada, Chile, Czechia, Denmark, Estonia, Hong Kong, Hungary, Italy, Japan, New Zealand, Por... and more
Celgene

Withdrawn

A Study of Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Adult and Adolescent Subjects With Active Crohn's Disease

Crohn Disease

United States, Spain, Belgium, Denmark, Canada, Australia, Austria, United Kingdom, Netherlands, Italy, Korea, Republic of, Germany, Portugal, Croatia, Czechia, Greece, Hungary, Israel, Poland, Russian Federation, Serbia, Slovakia, ... and more
GlaxoSmithKline

Completed

A Study to Investigate the Efficacy and Safety of GSK1605786A in the Treatment of Subjects With Moderately-to-Severely Active Crohn's Disease (SHIELD-1)

Crohn's Disease

United States, France, Netherlands, Spain, Germany, Poland, Belgium, South Africa, Sweden, Israel, Korea, Republic of, Australia, Austria, Canada, Czechia, Denmark, Hungary, Italy, Japan, New Zealand, Norway, Slovakia, United Kingdom
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy and Safety of NNC0114-0006 in Subjects With Active Crohn's Disease

Inflammation | Crohn's Disease

United States, Spain, Bulgaria, Czech Republic, Poland, Slovakia
AbbVie (prior sponsor, Abbott)

Completed

A Long-Term Registry of Humira® (Adalimumab) in Subjects With Moderately to Severely Active Crohn's Disease (CD)

Crohn's Disease
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Efficacy of MT-1303 in Subjects With Moderate to Severe Active Crohn's Disease

Crohn's Disease

France, Israel, Italy, Netherlands, Poland, Slovakia, Ukraine, Czech Republic, Germany, Hungary, Japan
Janssen Research & Development, LLC

Completed

Safety and Efficacy of NNC 0142-0000-0002 in Subjects With Moderately to Severely Active Crohn's Disease

Inflammation | Crohn's Disease

Belgium, France, Israel, Hungary, Russian Federation, Poland, Canada, United States
Galapagos NV

Completed

Efficacy and Safety of GLPG0634 in Subjects With Active Crohn's Disease

Crohn's Disease

United Kingdom, Belgium, France, Hungary, Russian Federation, Czech Republic, Germany, Poland, Romania
Eisai Inc.

Withdrawn

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of 3 Subcutaneous and 1 Intravenous Dose of E6011 in Subjects With Active Crohn's Disease

Crohn's Disease
GlaxoSmithKline

Completed

Nine-Weeks Treatment With 683699 In Subjects With Moderately-To-Severely Active Crohn's Disease

Crohn's Disease

United States, Canada
University of Erlangen-Nürnberg Medical School
Abbott

Completed

Safety and Tolerability of FITC-Adalimumab Administration During Confocal Laser Endomicroscopy of the Gut (FA-Crohn)

Crohn's Disease

Germany
Abbott

Terminated

Dose Ranging Study Comparing the Efficacy, Safety and Pharmacokinetics of Intravenous Infusions of ABT-874 vs Placebo in Subjects With Active Crohn's Disease

Crohn's Disease

United States, Australia, Austria, Belgium, Canada, Denmark, Puerto Rico
Cosmetique Active International

Recruiting

Evaluation of Effaclar Duo+M on Acne Lesions in Subjects With Mild to Moderate Acne on Face and Trunk

Acne

Brazil
VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Lupus Nephritis

China
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

Ankylosing Spondylitis

China
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Lynk Pharmaceuticals Co., Ltd

Recruiting

A Study of LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis

Rheumatoid Arthritis

China
CMC Ambroise Paré
Celltrion HealthCare France; Paris IBD Center

Not yet recruiting

Pharmacokinetics, Efficacy and Safety of CT-P13 Subcutaneous as Induction Therapy in Patients With Active CD or UC (PASSPORT)

Inflammatory Bowel Diseases
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Australia, France, Taiwan, Hungary, Korea, Republic of, Spain, Switzerland, China, Japan, Belgium, Canada, Germany, Italy, Poland, Romania, United Kingdom, Czechia, Denmark, Greece, Norway, Slovakia, Netherlands
Morphic Therapeutic, Inc

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

Inflammatory Bowel Diseases | Crohn's Disease

United States, Georgia
Cabaletta Bio

Recruiting

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy

Idiopathic Inflammatory Myopathy | Dermatomyositis | Immune-Mediated Necrotizing Myopathy | Anti-Synthetase Syndrome

United States
Orchard Therapeutics

Recruiting

A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT (HURCULES)

MPS-IH (Hurler Syndrome)

Netherlands, United States, Italy, United Kingdom
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Sling Therapeutics, Inc.

Recruiting

A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan

Crohn's Disease

Japan
Respirion Pharmaceuticals Pty Ltd

Recruiting

A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

Pseudomonas Aeruginosa | Cystic Fibrosis Lung | Respiratory Infections, Recurrent, Chronic

United States, Australia
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Korea, Republic of, Taiwan, Israel, Switzerland, United Kingdom, Puerto Rico, Turkey, Spain, Bulgaria, Belgium
Liveome Inc.

Recruiting

A Study of LIV001 in Healthy Subjects and Those With Mild-to-Moderate Active Ulcerative Colitis (UC)

Ulcerative Colitis

Australia
Mineralys Therapeutics Inc.

Recruiting

Open-Label Extension Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Uncontrolled Hypertension

Hypertension

United States, Puerto Rico
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease (MACARONI-23)

Crohn's Disease

Poland, United States, Japan, Spain, Norway, Italy
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

Efficacy and Safety Study of Jaktinib in Subjects With Active Ankylosing Spondylitis(AS)

Ankylosing Spondylitis

China
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events In Adult Participants With Moderate to Severe Active Crohn's Disease (CD) (APPRISE)

Crohn's Disease

Canada, France, Austria, Germany, Japan, Israel, Switzerland, Spain, United Arab Emirates
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Efficacy and Safety Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.

Active Ankylosing Spondylitis

China
RemeGen Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Telitacicept in Subjects With Active Primary Sjogren's Syndrome

Primary Sjogren's Syndrome

China
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation

Functional Constipation (FC) | Chronic Idiopathic Constipation (CIC)

United States, United Kingdom, Bulgaria, Netherlands

3

Subscribe