Search clinical trials for: Syndrome of Inappropriate Anti Diuretic Hormone (SIADH)

Total 443354 results

Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
Sanofi

Terminated

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia (AQUARIST1)

Hyponatremia | Inappropriate ADH Syndrome

United States
Otsuka Frankfurt Research Institute GmbH

Unknown

Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice

SIADH | Non-SIADH Hyponatremia | Non-Hyponatremia

Denmark, Germany, Italy, Norway, Spain, Sweden, United Kingdom
University of Erlangen-Nürnberg Medical School

Completed

Tolvaptan Versus Fluid Restriction in SIADH

Hyponatremia | Pituitary | Syndrome of Inappropriate ADH (SIADH) Secretion
Helbert Rondon Berrios, MD, MS
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Urea for Chronic Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome

United States
University of Wuerzburg

Completed

Subclassification of the Syndrome of Inappropriate ADH Secretion

Hyponatremia

Germany
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy (ASSERT)

Cancer | Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Italy
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain (ALGA)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Spain
King's College Hospital NHS Trust

Recruiting

Low-dose Tolvaptan for Inpatient Hyponatraemia.

Hyponatremia | SIADH

United Kingdom
Sanofi

Completed

Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

France, Germany, Belgium, Hungary
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome | Water Intoxication | Water-electrolyte Imbalance

Germany
Polderman, Kees, H., MD, PhD
University of Pittsburgh

Terminated

Tolvaptan for Patients With Acute Neurological Injuries

Hyponatremia | SIADH

United States
Mario Negri Institute for Pharmacological Research
A.O. Ospedale Papa Giovanni XXIII

Terminated

Tolvaptan for In-hospital Hyponatremia (INSERT)

Hyponatremia

Italy
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Inappropriate ADH Syndrome | Water Intoxication | Hyponatremias | Water-Electrolyte Imbalances

United States
Sanofi

Completed

Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia | Inappropriate ADH Syndrome

United States, Canada, Brazil, Germany, Netherlands, Portugal, Spain, Belgium, Croatia, Hungary, Hong Kong
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH

Antidiuretic Hormone, Inappropriate Secretion

Japan
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study (SANDx)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
Sanofi

Completed

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH Safety)

Hyponatremia | Inappropriate ADH Syndrome

United States, France, Brazil, Russian Federation, Australia, Germany, Switzerland, Belgium, Hungary, Hong Kong, Canada
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Japan
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With SIADH - the SAND Study (SAND)

SIADH

Switzerland
Zealand University Hospital

Unknown

Hyponatraemia and Mortality in Schizophrenic and Bipolar Patients: Protocol for a Bayesian Causal Inference Study

Hyponatremia | SIADH
University Hospital, Montpellier

Recruiting

Prevalence, Severity, Risk Factors, and Prognostic Value of Hyponatremia in Patients With Traumatic Brain Injury (WATERWAR)

Traumatic Brain Injury

France
University Hospital, Grenoble

Recruiting

Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage (NAT-URE)

Subarachnoid Hemorrhage | Hyponatremia | SIADH

France
University Hospital, Basel, Switzerland
Kantonsspital Aarau

Completed

Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis

Pituitary Adenoma

Switzerland
NYU Langone Health

Withdrawn

Fractional Urate Excretion in Nonedematous Hyponatremia

SIADH | Cerebral Hyponatremia | Cerebral Salt-wasting Syndrome | Reset Hypothalamic Osmostat

United States
Hadassah Medical Organization

Unknown

The Clinical and Laboratory Characteristics of Recurrent Drug- Related Hyponatremia (0597-10-HMO)

Hyponatremia | SIADH

Israel
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia

Euvolemic Hyponatremia

United States, Israel, India, Mexico, Peru, Belgium, Czech Republic, Italy
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430

Hyponatremia With Excess Extracellular Fluid Volume | Hyponatremia With Normal Extracellular Fluid Volume

United States
Hospital San Carlos, Madrid

Completed

Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia

Hyponatremia | Hypovolemia | SIADH

Spain
University Hospital, Basel, Switzerland

Completed

The "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)

Stroke | Transient Ischemic Attack

Switzerland
University Hospital Inselspital, Berne
Brahms AG; Foundation for research in Anaesthesie and Intensive Care Medicine

Completed

Electrolyte and Fluid Disturbances in Subarachnoid Hemorrhage and Traumatic Brain Injury

Traumatic Brain Injury | Subarachnoid Hemorrhage | Natriuretic Peptides | Electrolyte Disturbances

Switzerland
Universitair Ziekenhuis Brussel

Recruiting

Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome

Frailty | Asymptomatic Bacteriuria | Geriatric Syndrome | SIADH

Belgium
University Hospital, Basel, Switzerland
Centre Hospitalier Universitaire Vaudois; Luzerner Kantonsspital

Recruiting

Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia (EMPOWER)

Liver Failure | Hyponatremia | Kidney Failure | SIADH

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD (ESCAPE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
Incannex Healthcare Ltd

Recruiting

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA (REPOSA)

Obstructive Sleep Apnea

United States
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Incannex Healthcare Ltd

Recruiting

Bioavailability, Bioequivalence and Tolerability of IHL-42X Compared to the Reference Drugs

Obstructive Sleep Apnea

Australia
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF) (STERO-AHF)

Acute Heart Failure

Italy
St. Joseph's Healthcare Hamilton
McMaster University; Hamilton Academic Health Sciences Organization

Recruiting

Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder

Bipolar Disorder | Premenstrual Dysphoric Disorder

Canada
Fudan University

Recruiting

Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety (PCOS)

Depression, Anxiety | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
IRCCS Azienda Ospedaliero-Universitaria di Bologna; University of Milan

Not yet recruiting

Efficacy of Canrenone as add-on Treatment in Moderate to Severe ARDS in COVID-19 (MINECRAFT)

COVID-19 Acute Respiratory Distress Syndrome
Brigham and Women's Hospital

Recruiting

Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity

Hypertension | Metabolic Syndrome | Overweight and Obesity

United States
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Martin Schrappe
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017

Acute Lymphoblastic Leukemia, Pediatric

Switzerland, Czechia, Israel, Italy, Germany, Australia, Austria, Slovakia
VA Office of Research and Development

Recruiting

Sleep Apnea in Elderly

Sleep Apnea | Elderly Adults

United States
University Hospital Goettingen
Society for Pediatric Nephrology (Germany); Deutsche Gesellschaft für Nephrologie and other collaborators

Recruiting

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Pediatric Kidney Disease | Alport Syndrome | Hereditary Kidney Disease | Thin Basement Membrane Disease | Familial Benign Hematuria

Germany
University of Virginia

Recruiting

Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia

United States
Satish R. Raj
National Center for Advancing Translational Sciences (NCATS)

Active, not recruiting

Treatment of Orthostatic Intolerance

Tachycardia | Chronic Orthostatic Intolerance

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore

Search clinical trials for: Syndrome of Inappropriate Anti Diuretic Hormone (SIADH)

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