Search clinical trials for: Tenosynovial giant cell tumor (TGCT)

Total 67863 results

Deciphera Pharmaceuticals LLC

Active, not recruiting

Study of Vimseltinib for Tenosynovial Giant Cell Tumor (MOTION)

Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse | Tenosynovial Giant Cell Tumor, Localized

Norway, United States, France, Spain, Hong Kong, Netherlands, Italy, Germany, Australia, United Kingdom, Canada, Poland, Switzerland
Plexxikon

Terminated

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Solid Tumor | Tenosynovial Giant Cell Tumor | Tumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion Mutations

United States
Deciphera Pharmaceuticals LLC

Active, not recruiting

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Advanced Malignant Neoplasm | Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse

United States, France, Spain, United Kingdom, Netherlands, Canada, Italy, Australia, Poland
SynOx Therapeutics Limited

Recruiting

Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT) (TANGENT)

TGCT

United States
Hutchison Medipharma Limited

Recruiting

Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT

Advanced Malignant Solid Tumors | TGCT

China
Abbisko Therapeutics Co, Ltd

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

Neoplasms | Tenosynovial Giant Cell Tumor

United States
AmMax Bio, Inc.

Terminated

A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | TGCT | PVNS - Pigmented Villonodular Synovitis

Poland, Ukraine, Hungary
Daiichi Sankyo, Inc.
Optimapharm

Completed

Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project (TOP)

Giant Cell Tumors

United States, France, Spain, Netherlands, Italy, Austria, United Kingdom, Germany
Five Prime Therapeutics, Inc.

Completed

Study of Cabiralizumab in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor (FPA008-002)

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis

United States, France, Netherlands, United Kingdom, Korea, Republic of, Poland
AmMax Bio, Inc.

Active, not recruiting

An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis

Poland, Ukraine, United States, Netherlands
AmMax Bio, Inc.

Recruiting

A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | TGCT

Netherlands, Australia, United States
Daiichi Sankyo Co., Ltd.

Active, not recruiting

A Study of the Efficacy and Safety of Pexidartinib in Adult Subjects With TGCT (PLX3397)

Tenosynovial Giant Cell Tumor

Taiwan, China
Centre Leon Berard
Ministry of Health, France

Completed

Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT)

Pigmented Villonodular Synovitis

France, Netherlands, Italy, Poland, United Kingdom
National Cancer Institute (NCI)

Completed

A Case-Control Study of Testicular Germ Cell Tumors Among U.S. Military Servicemen

Testicular Cancer

United States
Daiichi Sankyo, Inc.

Completed

Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib (PLX3397)

Tenosynovial Giant Cell Tumor

United States, Spain, Taiwan, Australia, Hungary, Italy, Netherlands
Daiichi Sankyo Co., Ltd.

Recruiting

A Study of Pexidartinib in Tenosynovial Giant Cell Tumor in Japan

Tenosynovial Giant Cell Tumor

Japan
Daiichi Sankyo, Inc.

Completed

Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

Moderate Hepatic Impairment

United States
Slovak Academy of Sciences
Comenius University

Active, not recruiting

Exercise in Testicular Germ Cell Cancer Survivors (ExCell)

Testicular Germ Cell Tumor

Slovakia
The University of Texas Health Science Center at...

Recruiting

Financial Toxicity and Quality of Life in Patients With TGCT

Testicular Neoplasm

United States
Daiichi Sankyo, Inc.

Completed

Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics)

Drug Interaction Potential

United States, New Zealand, Taiwan, Netherlands
Sanofi

Terminated

Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FARM)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Cameroon, Gabon, Kenya, Tanzania
Pfizer

Terminated

A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

Advanced Cancer

United States, Canada, United Kingdom, Taiwan, Australia, France, Japan, Poland
Daiichi Sankyo, Inc.

Recruiting

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

Tenosynovial Giant Cell Tumor | Hepatotoxicity

United States
National Cancer Institute (NCI)

Recruiting

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Sarcoma | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Neurofibroma, Plexiform | Leukemia, Promyelocytic, Acute

United States
Abbisko Therapeutics Co, Ltd

Active, not recruiting

Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)

Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis

Spain, China, United States, Netherlands, Italy, Canada, Poland
Andrew J. Wagner, MD, PhD
Massachusetts General Hospital; Novartis; Brigham and Women's Hospital

Active, not recruiting

Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | Diffuse-type Giant Cell Tumor

United States
Daiichi Sankyo, Inc.

Completed

Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS) (ENLIVEN)

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | Giant Cell Tumors of the Tendon Sheath

United States, France, Australia, Denmark, Spain, Netherlands, Germany, Canada, United Kingdom, Hungary, Italy, Poland
Novartis Pharmaceuticals

Completed

MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)

Pigmented Villonodular Synovitis | PVNS | Giant Cell Tumor of the Tendon Sheath | GCCTS | Tenosynovial Giant Cell Tumor Localized or Diffused Type | GCTS

United States, Switzerland
Plexxikon

Terminated

A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor

Solid Tumors | Tenosynovial Giant Cell Tumor | Synovitis, Pigmented Villonodular

United States
Peking University People's Hospital

Recruiting

Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells

Malignant Bone Tumor

China
HCA Healthcare Research Institute
Balt USA

Recruiting

Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry (OPTIMA)

Intracranial Aneurysm

United States
Shanghai JMT-Bio Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage

Giant Cell Tumor of Bone

China
Dana-Farber Cancer Institute

Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions

United States
Amgen

Recruiting

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Giant Cell Tumor of Bone

Taiwan, China
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel
National Cancer Institute (NCI)

Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Urethral Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Bladder Adenocarcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Bladder... and other conditions

United States, Puerto Rico
Global Healthy Living Foundation
University of Alabama at Birmingham

Recruiting

PatientSpot Formerly Known as ArthritisPower (GHLF)

Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions

United States
Leiden University Medical Center
Amgen

Recruiting

Denosumab in Subjects With Giant Cell Rich Tumors of Bone

Aneurysmal Bone Cysts | Giant Cell Granuloma | Osteoblastoma | Chondroblastoma | Chondromyxoid Fibroma

France, Italy, Netherlands
St. Louis University
Johns Hopkins University; Massachusetts General Hospital; Beth Israel Deaconess... and other collaborators

Recruiting

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

United States, Canada, India
St. Jude Children's Research Hospital

Recruiting

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

Melanoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Malignant Solid Neoplasm | Nasopharyngeal Carcinoma | Adenoid Cystic Carcinoma | Transitional Cell Carcinoma | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Chordoma | Gestational Trophoblastic Tumor | Pseudomyxoma Peritonei | Cervical Adenocarcinoma | Vaginal Adenocarcinoma | Vaginal Squamous Cell... and other conditions

United States, Guam
Amgen

Completed

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Giant Cell Tumor of Bone

Australia, France, United States, Spain, Italy, Poland, Sweden, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Active, not recruiting

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Malignant Solid Neoplasm | Soft Tissue Sarcoma | Recurrent Ovarian Carcinoma | Triple Negative Breast Cancer | Recurrent Osteosarcoma | Refractory Osteosarcoma | Bone Sarcoma | Giant Cell Tumor of Bone | Ovarian Carcinosarcoma | Platinum-Resistant Ovarian Carcinoma | Dedifferentiated Chondrosarcoma | Malignancy... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Neoplasm

United States
Paradigm Biopharmaceuticals USA (INC)

Active, not recruiting

An Observational Follow-up Study to Evaluate Duration of Treatment Effect of Pentosan Polysulfate Sodium in Participants With Knee Osteoarthritis Pain

Osteoarthritis, Knee

United States, Australia
Paradigm Biopharmaceuticals USA (INC)

Active, not recruiting

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

Osteoarthritis, Knee

Australia, United States
Memorial Sloan Kettering Cancer Center

Completed

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Metastatic Cancer | Neuroblastoma | Intraocular Melanoma | Melanoma (Skin) | Retinoblastoma

United States
Changye Zou

Completed

Network Pharmacology Prediction: Mechanism Study of Puerarin in the Treatment of Giant Cell Tumors of Bone

Giant Cell Tumors

China

Search clinical trials for: Tenosynovial giant cell tumor (TGCT)

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