Search clinical trials for: The effect of food on the pharmacokinetics of TC-5214

Total 480100 results

Targacept Inc.

Completed

Study Evaluating the Safety, Tolerability, and Efficacy of Dexmecamylamine (TC-5214) for Treatment of Overactive Bladder

Overactive Bladder

United States
AstraZeneca

Completed

Study in Healthy Subjects to Measure the Effects of Food on the Pharmacokinetics of TC-5214 (TC-5214)

Healthy Subjects

United States
Atacama Therapeutics

Completed

Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States
Targacept Inc.

Terminated

TC-5214 as Augmentation Therapy in Patients With Refractory Hypertension

Refractory Hypertension

United States
AstraZeneca

Completed

A Study to Assess Safety and Tolerability as Well as Absorption and Excretion of TC-5214 in Medically Stable Elderly Subjects

Elderly Subjects 65 Years and Older, Healthy or With a Stable Disease and Treatment.

Sweden
AstraZeneca

Completed

To Compare the Pharmacokinetics of a Single Oral Dose of TC-5214 in Subjects With Renal Impairment and With Subjects With Normal Renal Function

Renal Impairment | Healthy Volunteers | Pharmacokinetics | Patients

United States
AstraZeneca

Completed

A Study of Single and Multiple Ascending Doses of TC-5214 in Japanese Healthy Elderly Male and Female Volunteers

Healthy

Japan
AstraZeneca

Completed

To Investigate Safety, Tolerability and Pharmacokinetics of TC-5214 in Healthy Male Japanese Subjects

Healthy
AstraZeneca

Withdrawn

Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214 (TC-5214)

Healthy | Drug Abuse
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder (MDD)

Depression | Major Depressive Disorder

United States, India
AstraZeneca

Completed

To Investigate the Safety and Tolerability of TC-5214 Following Oral Administration of Multiple Doses for up to 8 Days

Healthy

United States
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Depression | Major Depressive Disorder | MDD

United States, Puerto Rico
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Depression | Major Depressive Disorder

United States, India, Puerto Rico
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Depression | Major Depressive Disorder

Sweden, Czech Republic, Poland, Germany, Estonia, Latvia, Lithuania, Finland, France, Hungary
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder.

Major Depressive Disorder

Croatia, Brazil, Bulgaria, France, Poland, Russian Federation, South Africa, Hungary, Romania, Ukraine, Argentina, Chile, Slovakia, Colombia, Germany, Serbia, Spain
AstraZeneca

Terminated

To Determine Blood Pressure Interaction Between TC-5214 and Anti-Hypertensive Medications (Calcium Channel Blockers, Beta Blockers, and ACE Inhibitors) in Patients With Chronic Hypertension

Chronic Hypertension

United Kingdom, Germany, United States
Targacept Inc.

Completed

TC-5214 as add-on the Treatment of Major Depressive Disorder

Depression | Major Depressive Disorder

United States, India
Assiut University

Unknown

Split Renal Function Using 99mTc-DTPA Versus 99mTc-DMSA in Kidney Patients of Wide Age Ranges.

The Difference in Estimation of Split Renal Function Using the Two Radiopharmaceuticals:Tc-99m DTPA & Tc-99m DMSA in Kidney Patients
AstraZeneca

Terminated

Determining Highest Dose Administration of TC-5214 and Evaluating Effect on the Electrical Activity in the Heart

Healthy Male

United Kingdom
AstraZeneca

Terminated

A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.

Major Depressive Disorder

United States, Estonia, Japan, Finland, India
Atacama Therapeutics

Active, not recruiting

Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Hyperhidrosis | Palmar Hyperhidrosis

United States
Wei Li

Recruiting

The Impact of Different Scanning Methods and Reconstruction Algorithms on CT Image Quality

CT Examination of the Abdomen

China
Yonsei University

Completed

The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Prospective Study

Children Requiring Sedation for MRI/CT

Korea, Republic of
Clear Guide Medical
Johns Hopkins University

Unknown

Ultrasound-CT Fusion System for Interventional Radiology Procedures

CT Guided Biopsy | CT Guided Drain Placement Within the Abdomen or Pelvis | CT Guided Injection of Muscle or Nerve Within the Pelvis

United States
Philips Healthcare (Suzhou) Co., Ltd.
The Second Hospital of Nanjing Medical University

Not yet recruiting

Incisive CT Clinica Trial Protocol

CT Images
Lument AB

Terminated

A Randomized, Controlled Trial to Evaluate CT Image Quality Lumentin® 44

Subjects Referred to CT-examination of the Abdomen

Sweden
Yonsei University

Unknown

The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Retrospective Study

Children Requiring Sedation for MRI/CT

Korea, Republic of
The University of Hong Kong

Active, not recruiting

Tai Chi-muscle Power Training for Primary School Children With Developmental Coordination Disorder

Developmental Coordination Disorder

Hong Kong
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation

Ultrasound | CT Scans | MRIs

United States, Puerto Rico
Daewoong Pharmaceutical Co. LTD.

Unknown

Observational Study to Assess the Safety of Omnipure® Inj.(Iohexol) Contrast Media in CT Scanning Patients

CT Scanning Patients

Korea, Republic of
Targacept Inc.

Completed

Study Evaluating the Effect of TC-6499 on Gastric Emptying Time in Diabetic Subjects With Gastroparesis

Gastroparesis

United States
New York State Psychiatric Institute

Terminated

Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression

Major Depression

United States
University Hospital, Montpellier

Completed

Systemic Air Embolism After CT-guided Lung Biopsy (SAE)

Patients Who Underwent Percutaneous Lung Biopsy Under CT Guidance | Patients Who Presented Systemic Air Embolism After Percutaneous Lung Biopsy Under CT Guidance Depicted at the Time of the Procedure on a Whole Thoracic CT

France
University of Cincinnati
National Cancer Institute (NCI); Ohio Third Frontier

Active, not recruiting

Validating Low FDG Dose PET/CT Compared to Current Standard of Care Dose PET/CT

PET/CT Imaging

United States
Cardiocentro Ticino

Unknown

Anesthetic Neurotoxicity: the Association Between General Anesthesia and the Level of Plasma Neurofilament Light (ANESTOX-2019)

General Anesthetics Toxicity

Switzerland
Vidacare Corporation

Terminated

Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route

Intraosseous Vascular Access Patients Requiring CT Exam

United States
Far Eastern Memorial Hospital

Completed

Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary Angiography (DSCT)

Coronary Angiography | CT

Taiwan
University Health Network, Toronto

Completed

Comparison Between Dual Energy/Subtraction CT With MRI for the Identification of Predictors of Malignancy in Cystic Pancreatic Lesions

Pancreatic Cyst

Canada
Xact Robotics Ltd.

Completed

Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures

CT-guided Minimally Invasive Procedures e.g., Biopsies

Israel, United States
Cairo University

Completed

Effect of Combination Therapy on Knee Osteoarthritis Pain in Postmenopausal Women

Non Specific Knee Osteoarthritis Pain

Egypt
GE Healthcare
Karolinska University Hospital

Not yet recruiting

Clinical Data Collection On Advanced CT System

CT Photon Counting
Smith & Nephew Medical (Shanghai) Ltd

Completed

TC-A Registration Study

Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Primary Osteoarthritis

China
Hartford Hospital

Unknown

The Impact of Oral Contrast in Multidetector CT of the Abdomen and Pelvis on Radiologist Confidence

Routine Outpatients Undergoing Contrast Enhanced CT Scan of the Abdomen and Pelvis

United States
Seoul National University Hospital

Completed

Comparison of NEOVIST 370 INJ.(Iopromide 768.86mg) With Ultravist 370 INJ.(Iopromide 768.86mg) in Abdominal CT

Abdominal CT
Xact Robotics Ltd.

Withdrawn

Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures

CT-guided Minimally Invasive Procedures e.g. Biopsies

United States, Israel
Royal Marsden NHS Foundation Trust
City, University of London

Unknown

Radiation Exposure Awareness From Patients Undergoing Nuclear Medicine Diagnostic Scans (REA)

FDG PET/CT | Skeletal Scintigraphy

United Kingdom
Centre Hospitalier Universitaire de Nīmes

Completed

Impact of Reconstruction Method (ASIR, FBP) Used in CT on Bone SPECT/CT Image Quality (AsirTest)

SPECT-CT

France
Lundquist Institute for Biomedical Innovation at...
General Electric

Completed

Comparison of Contrast Agents During CT Angiography (Visipaque)

Contrast Enhancement on Cardiac CT

United States
Targacept Inc.

Completed

Proof-of-Principle Study of TC-6499 in the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United Kingdom
Targacept Inc.

Completed

TC-6987 for the Treatment of Mild to Moderate Asthma

Asthma

United States

Search clinical trials for: The effect of food on the pharmacokinetics of TC-5214

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