Search clinical trials for: The aims are to assess efficacy of sodium butyrate enema in

Total 496266 results

International Centre for Diarrhoeal Disease Research...
Karolinska Institutet; Swedish International Development Cooperation Agency...

Completed

Therapeutic Induction of Endogenous Antibiotics

Shigellosis

Bangladesh
UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
AstraZeneca

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Chronic Kidney Disease and Hypertension

Spain, United States, Argentina, Denmark, Italy, Sweden, United Kingdom, Belgium, France, Turkey, China, Germany, Saudi Arabia, Thailand, Vietnam, Australia, Serbia, Brazil, Canada, Japan, Malaysia, Philippines, Poland, Taiwan, Greece, Is... and more
Centre Hospitalier Universitaire Vaudois
Fondation de Préfargier

Not yet recruiting

Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder

Major Depressive Disorder
Hope Medicine (Nanjing) Co., Ltd

Recruiting

A Study to Assess the Efficacy and Safety of HMI-115 in Male Subjects With Androgenetic Alopecia

Androgenetic Alopecia

China
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Gastric Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Gastric Cancer | Organoids

China
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Colorectal Cancer | Organoids

China
AstraZeneca
Parexel

Not yet recruiting

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus (LAVENDER)

Cutaneous Lupus Erythematosus

United States, Belgium, Germany, Italy, Spain, France, Korea, Republic of, Philippines, United Kingdom, China, Austria, Australia, Netherlands, Bulgaria, South Africa, Taiwan, Denmark, Poland, Serbia, Argentina, Chile, Brazil, Colombia and more
Unity Biotechnology, Inc.

Recruiting

Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE) (ASPIRE)

Eye Diseases | Diabetes Mellitus | Retinal Degeneration | Retinal Diseases | Edema | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

United States
StimuSIL
Ankara City Hospital Bilkent; Istanbul University - Cerrahpasa (IUC)

Recruiting

Assessing the Safety and Efficacy of a Novel Microneedling and Laser Device for Male Pattern Hair Loss (CS-SAGA-001)

Androgenetic Alopecia | Hair Loss | Male Pattern Baldness | Hair Loss/Baldness | Pattern Baldness

Turkey
Pharmazz, Inc.

Recruiting

A Study to Assess the Safety and Efficacy of Centhaquine in Hypovolemic Shock Patients

Hypovolemic Shock

India
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
Sarepta Therapeutics, Inc.
Hoffmann-La Roche

Recruiting

A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD) (ENVISION)

Duchenne Muscular Dystrophy

Belgium, United States, Japan, Spain, Italy, United Kingdom
NAOS Argentina S.A.

Recruiting

Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream Intended for Very Dry, Irritated to Atopic Sensitive Skin.

Atopic Dermatitis | Eczema, Atopic

Argentina, Singapore
Novartis Pharmaceuticals

Recruiting

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NEPTUNUS-2)

Sjogren Syndrome

Spain, Hungary, Germany, Canada, Greece, United Kingdom, Bulgaria, Japan, Colombia, United States, South Africa, Australia, China, Mexico, Israel, Lebanon, Taiwan, Argentina, Italy, France, Chile, Romania, India, Brazil, Poland, Slovakia, S...
Assistance Publique - Hôpitaux de Paris

Recruiting

Assessing the Tolerance and Clinical Benefit of feCAl tranSplantation in patientS With melanOma (PICASSO)

Melanoma

France
AgoneX Biopharmaceuticals, Inc.

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis

Migraine Prophylaxis
Bayer

Active, not recruiting

A Study to Learn More About How Acarbose and Metformin Work When Taken Together and How Safe They Are in Indian Patients Who Were Recently Diagnosed With Type 2 Diabetes (T2D) (START-AM)

Type 2 Diabetes Mellitus

India
AstraZeneca

Completed

Study Will Assess the Safety, Neutralizing Activity and Efficacy of AZD3152 in Adults With Conditions Increasing Risk of Inadequate Protective Immune Response After Vaccination and Thus Are at High Risk of Developing Severe COVID-19 (NOVELLA)

COVID-19, SARS-CoV-2

Russian Federation
Hoffmann-La Roche

Completed

Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like Symptoms

Influenza

Poland, United States, Costa Rica, Bulgaria, South Africa, Spain, Israel, Finland, Russian Federation
Colgate Palmolive

Completed

A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children

Dental Caries

United States, Puerto Rico
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Completed

A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis (VOYAGE)

Eosinophilic Esophagitis

United States, Spain, Switzerland, Australia, Belgium, Netherlands, Canada, Germany
Camurus AB

Completed

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegaly (ACROINNOVA 1)

Acromegaly

United States, Spain, United Kingdom, Germany, Russian Federation, Greece, Hungary, Italy, Poland, Turkey
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
AbbVie

Active, not recruiting

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Puerto Rico
Genentech, Inc.

Terminated

A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD) (GALLEGO)

Geographic Atrophy | Macular Degeneration, Age-Related

United States
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany
Nordic Biotic Sp. z o.o.
Medical University of Lodz

Completed

The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome (IBS-Plus)

Irritable Bowel Syndrome

Poland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer (SOLARIS)

Colorectal Adenocarcinoma

United States, Puerto Rico
Inventiva Pharma

Active, not recruiting

Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus (LEGEND)

Diabetes Mellitus, Type 2 | NASH - Nonalcoholic Steatohepatitis

United States, Belgium, France, Netherlands, United Kingdom
LEO Pharma

Completed

A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing Alopecia

Frontal Fibrosing Alopecia

United States
Colgate Palmolive

Active, not recruiting

Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.

Gingivitis | Plaque

United States
Eisai Inc.
Merck Sharp & Dohme LLC

Active, not recruiting

Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma

Renal Cell Carcinoma

Spain, Canada, Portugal, Korea, Republic of, Taiwan, United States, Netherlands, United Kingdom, Czechia, Italy, Finland, Greece, Romania, Australia, Poland, Russian Federation
UCB Pharma

Completed

An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathy

Painful Diabetic Neuropathy
Celgene

Active, not recruiting

A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

Leukemia, Myeloid, Acute

United States, France, Italy, Korea, Republic of, Spain, United Kingdom, Australia, Canada, Germany, Netherlands, Portugal, Switzerland, Belgium, Sweden
AbbVie

Completed

A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain

Endometriosis

United States, Canada, Puerto Rico
The University of Texas Health Science Center,...
National Institute of Nursing Research (NINR)

Active, not recruiting

Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth

Behavior, Risk

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Seromucinous Carcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian... and other conditions

United States, Puerto Rico
Sarepta Therapeutics, Inc.
Hoffmann-La Roche

Active, not recruiting

A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) (EMBARK)

Duchenne Muscular Dystrophy

United States, Japan, Taiwan, Belgium, Spain, Germany, Hong Kong, Italy, United Kingdom
Novartis Pharmaceuticals

Completed

Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC (COMPLEEMENT-1)

Breast Cancer

United States, Belgium, Canada, Italy, Spain, United Kingdom, Austria, Czechia, Hungary, Malaysia, Saudi Arabia, Taiwan, Argentina, France, Israel, Netherlands, Russian Federation, Hong Kong, Thailand, Lebanon, Bulgaria, Denmark, Po... and more
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Completed

Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

Alopecia Areata

United States, Canada
Michael Kremke
Aarhus University Hospital; Pharmacosmos A/S; University of Aarhus

Completed

A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery (PICS)

Anemia Postoperative

Denmark
Ribomic USA Inc

Completed

A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration (RAMEN)

Exudative Age-related Macular Degeneration

United States
GWT-TUD GmbH

Completed

ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy

Lymphoma, B-Cell | Lymphoma, T-Cell | Aggressive Non-hodgkin Lymphoma (aNHL)

Germany
Regeneron Pharmaceuticals

Completed

COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay

Healthy Participants

United States, Moldova, Republic of, Romania
Promomed, LLC

Completed

Study for Efficacy and Safety Assessment of the Drug RADAMIN®VIRO for COVID-19 Postexposure Prophylaxis

COVID-19

Russian Federation
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion (RAPTOR)

Branch Retinal Vein Occlusion

China, Austria, Czechia, Russian Federation, Taiwan, United Kingdom, Canada, Japan, United States, France, Israel, Germany, Italy, Hong Kong, Spain, Denmark, Slovakia, Puerto Rico, Switzerland

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