Search clinical trials for: Therapeutic effect assessment

Total 166755 results

University of Alabama at Birmingham

Not yet recruiting

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway (VITAL-IMPACT)

Cardiovascular Diseases | Obesity | Insulin Sensitivity/Resistance | Metabolic Disease | Energy Expenditure | Metabolism

United States
Soha mahmoud Hussien mahdy
Assiut University

Not yet recruiting

Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates

Patent Ductus Arteriosus
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Chronic Graft Versus Host Disease | Hematologic and Lymphocytic Disorder | Steroid Refractory Graft Versus Host Disease

United States
Merz Therapeutics GmbH
Heinrich-Heine University, Duesseldorf

Recruiting

Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia (RELY-CD)

Cervical Dystonia

Germany
Sahmyook University

Recruiting

Effects of Therapeutic Intervention Through Selective Functional Movement Assessment on Pain, Function, Balance and Gait in Patients With Chronic Nonspecific Neck Pain

Chronic Nonspecific Neck Pain

Korea, Republic of
Centre Hospitalier St Anne

Not yet recruiting

Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation (STRATIDEP)

Major Depressive Disorder

France
Henan Cancer Hospital
Fundamenta Therapeutics, Ltd.

Not yet recruiting

Assessment of Safety and Efficacy of ThisCART19A in Adult Patients With B Cell Malignancies After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy

Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited

China
Ain Shams University

Not yet recruiting

Assessment of Rituximab Therapeutic Response Versus Conventional Treatment

Pharmacological Action
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Celldex Therapeutics

Recruiting

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Serous Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Recurrent Fallopian... and other conditions

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Natural Progesterone for the Treatment of Recurrent Glioblastoma

Gliosarcoma | Recurrent Glioblastoma

United States
Dr. August Wolff GmbH & Co. KG Arzneimittel
Therapeutics, Inc.

Not yet recruiting

Assessment of Safety, Tolerability and Efficacy of 1% GPB Cream Versus Qbrexza® (Glycopyrronium) Cloth 2.4% Under Maximum-Use Conditions in Subjects With Primary Axillary Hyperhidrosis

Primary Axillary Hyperhidrosis
National Research Center for Rehabilitation Technical...

Recruiting

Developing Effectiveness Evaluation and Therapeutic Programs of Rehabilitation

Dysphagia | Healthy Volunteers | Motor Deficits

China
Yale University
National Cancer Institute (NCI)

Recruiting

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

Stage IV Prostate Adenocarcinoma AJCC v7

United States, Taiwan, Korea, Republic of, Australia, China, Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Sleep Disorder

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer

Stage IB Breast Cancer AJCC v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | HER2-Positive Breast Carcinoma | Hormone Receptor-Positive Breast Carcinoma

United States, Puerto Rico
Haukeland University Hospital

Completed

IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC (IMPACT)

Ovarian Cancer

Norway
University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Acute Myeloid Leukemia

United States, Canada, Puerto Rico, Australia
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease

Breast Cancer | brca1 Mutation Carrier | brca2 Mutation Carrier

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
Thomas Jefferson University
Context Therapeutics Inc.

Active, not recruiting

Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial Cancer

Refractory Endometrial Carcinoma | Refractory Endometrial Endometrioid Adenocarcinoma | Refractory Endometrial Adenocarcinoma | Refractory Endometrial Clear Cell Adenocarcinoma | Refractory Endometrial Mixed Cell Adenocarcinoma | Refractory Endometrial Serous Adenocarcinoma | Refractory Endometrial...

United States
University of Cincinnati

Active, not recruiting

Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics

Coronary Artery Disease

United States
ADC Therapeutics S.A.

Completed

A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL) (LOTIS-9)

Diffuse Large B-cell Lymphoma

Spain, United States, Italy, Puerto Rico
University of Alcala

Completed

Effectiveness of Hypopressive Exercises Versus Pelvic-perineal Physiotherapy (HEPFD)

Urinary Incontinence | Pelvic Pain | Pelvic Floor Disorders | Fecal Incontinence

Spain
Heron Therapeutics

Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

Analgesia

United States
Heron Therapeutics

Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

Postoperative Pain | Multimodal Analgesia | Total Shoulder Arthroplasty

United States
Heron Therapeutics

Active, not recruiting

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Analgesia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
National Cancer Institute (NCI)

Completed

Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast Cancer

Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage 0 Breast Cancer AJCC v6 and v7

United States, Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study

Low Anterior Resection Syndrome | Malignant Uterine Neoplasm | Rectal Carcinoma | Malignant Ovarian Neoplasm | Malignant Pelvic Neoplasm | Malignant Anal Neoplasm | Malignant Bladder Neoplasm | Malignant Cervical Neoplasm | Malignant Prostate Neoplasm | Malignant Vaginal Neoplasm | Malignant Vulvar Neoplasm

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Active, not recruiting

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

Ductal Breast Carcinoma In Situ

United States
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Children's Hospital of Fudan University

Completed

Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Children With Cerebral Palsy

Cerebral Palsy | Acupuncture | Motor Dysfunction

China
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
University of South Florida
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Arthritis... and other collaborators

Active, not recruiting

The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach (TAPIR)

Vasculitis | Granulomatosis With Polyangiitis | Wegener Granulomatosis

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Terminated

PReventing the EffectS of Intubation on DEglutition (PRESIDE)

Deglutition Disorders | Mechanical Ventilation Complication | Complication of Ventilation Therapy

United States
Jupiter Orphan Therapeutics Inc.
National Institute on Aging (NIA)

Completed

JOTROL PK, Safety, and Food Effect Assessment

Pharmacokinetics | Food-drug Interaction | Safety

United States
AbbVie
KU Leuven; Syndesi Therapeutics

Completed

A Single Ascending Oral Dose Study of SDI-118 in Healthy Male Subjects Including an Assessment of Receptor Occupancy and Food Effect

Cognitive Disorders

Belgium
ES Therapeutics Australia Pty Ltd

Withdrawn

ES-481 for Uncontrolled Glioma-Associated Epilepsy and Assessment for Potential Anti-Tumorigenic Effect in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Tumors

Epilepsy; Seizure
Centrexion Therapeutics

Completed

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Knee Osteoarthritis

United States
Immunoflex Therapeutics Inc.
University of British Columbia; Dicentra Inc.

Completed

Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy Participants

Immunity Disorders

Canada
Methodist Health System

Enrolling by invitation

Utility Assessment of a Pharmacy-to-Dose Daptomycin

Antibiotics Causing Adverse Effects in Therapeutic Use

United States
Ishrat Rahman

Completed

The Clinical Assessment of Nigella Sativa Oil vs Chlorohexidine as a Therapeutic Aid for Gingivitis, Effect on Gingival IL-6 and IL-18 and Antimicrobial Efficacy.

Gingivitis

Saudi Arabia
Pfizer's Upjohn has merged with Mylan to form Viatris...
The Cleveland Clinic

Completed

Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen (PRECISION)

Arthritis, Rheumatoid

United States, Taiwan, Philippines, Mexico, Canada, Australia, Colombia, Brazil, Ukraine, Costa Rica, Hong Kong, Panama, Peru
Esperion Therapeutics, Inc.

Completed

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia

High Grade Squamous Intraepithelial Neoplasia | Stage 0 Uterine Corpus Cancer

United States
Isofol Medical AB

Completed

Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer

Colorectal Neoplasm

Denmark, Norway, Greece, Sweden
Calo Psychiatric Center

Completed

Therapeutic Effect of Cassia Seed in Obesity of Patients With Schizophrenia

Schizophrenia

Taiwan
Istituto Ortopedico Galeazzi

Unknown

Evaluation of Enhanced Therapeutic Effect of Adipose Stromal Vascular Fraction Added With Human Platelet Lysate in Treatment of Osteoarthritis

Assessment of the Trophic and Anti-inflammatory Effect of SVF Added With HPL

Search clinical trials for: Therapeutic effect assessment

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