Search clinical trials for: Thorough QT (TQT)

Total 590 results

Wex Pharmaceuticals Inc.
Celerion

Completed

A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate the Cardiovascular Effect of Tetrodotoxin in Healthy Adult Subjects

TQT Study

United States
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Pfizer

Completed

Phase 1 Thorough QT (TQT) Study in Young Healthy Volunteers (TQT)

Fibromyalgia

Belgium
Calico Life Sciences LLC
AbbVie

Recruiting

A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects

Healthy

United States
Wockhardt

Completed

Study to Evaluate the Effect Of WCK 2349 on the QT/QTc Interval in Health Volunteers

Qt Interval, Variation in

United States
VIVUS LLC

Completed

A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers (TQT)

Torsades de Pointes

United States
Astellas Pharma Inc

Completed

A Study of the Effect of ASP1941 on Cardiac Repolarization in Healthy Subjects

Healthy Subjects | Cardiac Repolarization

United States
Pfizer

Completed

CP-690,550 Thorough QTc Study

Healthy

Singapore, Belgium
Acacia Pharma Ltd

Completed

Thorough QT Study of Intravenous Amisulpride

Healthy
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Celgene

Completed

A Phase 1 QT Study in Healthy Male Subjects (QT/QTc)

Clinical Pharmacology, Healthy Volunteer Study

United States
FORUM Pharmaceuticals Inc
Quintiles, Inc.

Completed

Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects (TQT)

Healthy Subjects | Cardiac Repolarization
Mylan Inc.
Theravance Biopharma

Completed

Thorough QT (TQT) Study of TD-4208 in Healthy Subjects

Cardiac Repolarization in Healthy Subjects

United States
Pacira Pharmaceuticals, Inc
Richmond Pharmacology Limited

Completed

Phase 1 Thorough QT Study in Young Healthy Volunteers (TQT)

Postoperative Pain

United Kingdom
Usona Institute

Completed

An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics

Pharmacokinetics | QTc Interval

United States
Chiesi Farmaceutici S.p.A.

Completed

A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV)

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Achieve Life Sciences
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization

Cardiac Conduction and Repolarization

United States
Pfizer

Completed

A Phase 1 Study To Evaluate The Effect Of Glasdegib On The Cardiac Repolarization In Healthy Subjects (B1371023)

Healthy Volunteers

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects

Gonococcal Infection | Electrocardiogram Repolarisation Abnormality

United States
AstraZeneca

Completed

Investigate the Effect on the QT/QTc Interval of Repeated and Escalating Doses of AZD3480 During 6 Days (TQT)

Healthy
Genfit
Eurofins Optimed; PhinC Development; CardiaBase

Completed

Phase I Study to Evaluate the Effect of GFT505 on QT/QTc Interval in Healthy Volunteers

Healthy Volunteers

France
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Vantia Ltd

Completed

A Study in Healthy Volunteers to Assess the Effect of Fedovapagon on the QT/QTC Interval

Healthy

Germany
LG Chem

Completed

Thorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Female Subjects

Hyperuricemia | Gout | Qt Interval, Variation in

United States
Teva Branded Pharmaceutical Products R&D, Inc.
Cetero Research, San Antonio

Completed

A Phase 1 Study to Investigate the Effects of Talampanel on the Heart Rhythm

Healthy

United States
BioLineRx, Ltd.
Celerion

Completed

Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects

Healthy Subjects

United States
Impax Laboratories, LLC

Completed

A TQT Study to Evaluate the Electrocardiographic Effects of Carbidopa in Healthy Subjects

Cardiac Repolarization in Healthy Subjects

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Study to Evaluate The Effect Of Sertraline on the Cardiac Repolarization in Healthy Subjects (Zoloft)

Healthy

Belgium
Akebia Therapeutics

Completed

Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers

Healthy Volunteers

United States
Acorda Therapeutics

Completed

A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial (TQT)

Spasticity

United States
Merck Sharp & Dohme LLC

Completed

A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019) (TQT)

Schizophrenia

United States
Boehringer Ingelheim

Completed

This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study)

Healthy

Germany
Janssen Research & Development, LLC

Completed

A Thorough QT Study of Aticaprant (JNJ-67953964) in Healthy Adult Participants

Healthy

Belgium
Altavant Sciences GmbH
Altasciences Clinical Kansas, Inc.

Completed

Thorough QT Study to Evaluate the Effect of Rodatristat Ethyl, Rodatristat and Its Major Metabolites on the Heart

Healthy

United States
Alexion
PPD; ERT: Clinical Trial Technology Solutions

Completed

A Study of the Cardiac Effects of ALXN1840 in Healthy Adults

Healthy

United States
AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
Emalex Biosciences Inc.
PPD; Clario

Completed

Thorough QT/QTc Study to Evaluate the Effects of Ecopipam (EBS-101) on Cardiac Repolarization

QT/QTc

United States
Jazz Pharmaceuticals

Completed

Sativex Thorough QT/QTc Study

Effects of Sativex on ECG

Canada
AstraZeneca

Terminated

A Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants

Non-alcoholic Steatohepatitis

Germany
Astex Pharmaceuticals, Inc.

Completed

Thorough QT Assessment of Cedazuridine in Healthy Subjects

Healthy Volunteers

Netherlands
Organon and Co

Completed

Thorough QT/QTc Study of Multiple Oral Doses of NOMAC-E2 (Org 10486 0 + Org 2317) in Healthy Women (Study 292011)(P05802)

Contraception
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

A Study to Evaluate the Effect of Volanesorsen on Cardiac Repolarization Conducted in Healthy Volunteers

Abnormalities, Cardiovascular

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization

Normal Healthy Subjects
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults

QT Intervals Changes | QTc Intervals Changes

United Kingdom
Theravance Biopharma

Completed

Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects

Symptomatic Neurogenic Orthostatic Hypertension | nOH

United States
Bayer

Completed

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Medical Oncology

United States, Belgium, Spain, France, Netherlands, Australia
David Grant U.S. Air Force Medical Center

Terminated

Evaluation of Energy Drinks on Electrocardiographic, Vascular and Hematologic Parameters in Healthy Volunteers

Cardiovascular Diseases

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)

Healthy

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Loxapine Thorough QT/QTc Study

Thorough QT/QTc Study

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine Thorough QT/QTc

Cardiotoxicity

United States

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