Search clinical trials for: Time to Treatment Failure

Total 476965 results

Academisch Ziekenhuis Maastricht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Timely Recovery After Subclinical Heart Failure (TREASURE)

Heart Failure | Diastolic Dysfunction

Netherlands
HuiKai Li

Not yet recruiting

Hepatic Artery Infusion of Adebrelimab Combined With Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma With Failure of Systemic Therapy Combined With Interventional Therapy

Hepatocellular Carcinoma

China
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY BD)

Bipolar Depression

Austria, Germany, Italy, Spain, United Kingdom
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY SZ)

Schizophrenia and Related Disorders | Early Treatment-Resistance

Austria, Germany, Italy, Spain, United Kingdom
Dr. Inge Winter
Universität Münster

Not yet recruiting

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (INTENSIFY)

Bipolar Depression | Major Depressive Disorder | Schizophrenia and Related Disorders

Israel
Shandong University

Not yet recruiting

A Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Helicobacter Pylori Infection
Centre Leon Berard

Recruiting

A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments (ATEZOGIST)

Metastatic Gastrointestinal Stromal Tumor | Unresectable Gastrointestinal Stromal Tumor (GIST) | Locally Advanced Gastrointestinal Stromal Tumor (GIST)

France
Hepatopancreatobiliary Surgery Institute of Gansu...
The First Affiliated Hospital of Anhui Medical University; Xiangya Hospital... and other collaborators

Recruiting

Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)

Hepatic Encephalopathy | Cirrhosis

China
Centre Leon Berard

Recruiting

Efficacy of the Combination of Nivolumab and Ipilimumab as a Treatment in Patients With Sarcoma of Rare Subtype (RAR-Immune)

Sarcoma

France
Centre Leon Berard

Recruiting

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients (REGOMAIN)

Osteosarcoma | Bone Sarcoma

France
Centre Leon Berard

Recruiting

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas (REGOSTA)

Osteosarcoma | Ewing Sarcoma | Chondrosarcoma | Leiomyosarcoma | Angiosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma

France
Skane University Hospital
Lund University; Blekinge County Council Hospital

Completed

REgistry-based Treatment Duration and Mortality in Long-term OXygen Therapy (REDOX) (REDOX)

Chronic Respiratory Failure With Hypoxia

Sweden
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU) (TIME)

Communication | Palliative Care | Critical Care | Acute Respiratory Failure | Mechanical Ventilation | Decision Making | Life-Supporting Treatments

United States
University of New Mexico
Medical University of South Carolina; The Cleveland Clinic; Tufts Medical Center and other collaborators

Completed

Blood Pressure in Dialysis Patients (BID)

Hypertension | Blood Pressure | Dialysis | Renal Failure Chronic Requiring Hemodialysis

United States
Rennes University Hospital

Completed

Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments (ESOGIA)

Non Small-cell Lung Cancer

France
Novartis Pharmaceuticals

Completed

Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States, Canada
Shandong University
The Affiliated Hospital of Qingdao University; Taian City Central Hospital; Weifang... and other collaborators

Completed

The Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Helicobacter Pylori Infection

China
Shandong University
The Affiliated Hospital of Qingdao University; Taian City Central Hospital; Weifang... and other collaborators

Completed

The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Helicobacter Pylori

China
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Quality of Life in Heart Failure

Heart Failure | Quality of Life

United States
Prisma Health-Upstate
Albert Einstein College of Medicine; Clemson University

Completed

Intensive Models of HCV Care for Injection Drug Users

Hepatitis C | Medication Adherence

United States
Mario Negri Institute for Pharmacological Research

Terminated

Insulin Treatment in Diabetic Older People With Heart Failure. (Insulin-HF)

Heart Failure | Diabetes Mellitus, Type 2

Italy
Centre Leon Berard
GlaxoSmithKline

Completed

Phase II Study of the Optimal Scheme of Administration of Pazopanib in Thyroid Carcinoma

Thyroid Carcinoma

France
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings (PEARLS)

HIV Infections

United States, Brazil, Peru, India, Malawi, Haiti, South Africa, Thailand, Zimbabwe
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)

Heart Failure

United States, Canada
Amsterdam UMC, location VUmc
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Can High Convection Volumes be Achieved in Each Patient During Online Post-dilution Hemodiafiltration?

Renal Replacement Therapy | End-stage Renal Disease | Hemodiafiltration | Convection Volume

Netherlands
Karolinska Institutet

Completed

Long-term Effects of Intensive Insulin Treatment in Type 1 Diabetes (SDIS)

Stroke | Renal Failure | Coronary Heart Disease

Sweden
Hoffmann-La Roche

Completed

An Observational Study of Erlotinib (Tarceva) as Second-line Treatment in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer After Failure of Pemetrexed in First-line Therapy (TIME)

Non-Squamous Non-Small Cell Lung Cancer

Belgium
AbbVie (prior sponsor, Abbott)
Planimeter Ltd

Completed

Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands

Kidney Failure, Chronic

Hungary
Imperial College London

Unknown

Effects of Extended Haemodialysis Treatment Duration in Patients With End-stage Renal Disease

End Stage Renal Disease

United Kingdom
University of Utah

Completed

The Development of Tolerance to α1-Adrenoceptor Blockade With Chronic Carvedilol Treatment

Heart Failure

United States
Eli Lilly and Company

Completed

Somatropin Treatment in Patients With SHOX Deficiency and Turner Syndrome

Failure to Thrive

United States
Technische Universität Dresden

Completed

Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

Germany
Eli Lilly and Company

Completed

Gemcitabine Plus Cisplatin Single Dose Versus Split Dose in the Treatment of Patients With Locally Advanced or Metastatic Breast Cancer After Failure of Anthracyclines and/or Taxanes

Metastatic Breast Cancer

Saudi Arabia
Samaritan Biologics
Emergent Clinical Consulting, LLC

Not yet recruiting

Evaluating the Efficacy of Perinatal Membrane Allografts for the Treatment of Diabetic Foot Ulcers.

Diabetic Foot Ulcer
University of Sao Paulo General Hospital
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Not yet recruiting

Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

Heart Failure | Heart Transplant

Brazil
Fudan University

Recruiting

Clinical Study of T3011 Intravesical Instillation for Treatment of NMIBC Patients

Bladder Cancer

China
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Aplastic Anemia

China
Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Ductal Adenocarcinoma

United States
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Erasmus Medical Center
Arrow International LCC (Subsidiary of Teleflex Inc.)

Not yet recruiting

Clinical Effects of Intra-aortic Balloon Support in Early Acute Coronary Syndrome and Non-Acute Coronary Syndrome Related Cardiogenic Shock (IABP ON-TIME)

Cardiogenic Shock

Netherlands
Cairo University
National Heart Institute, Egypt

Not yet recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Edema | Acute Decompensated Heart Failure | Volume Overload

Egypt
XIANG YANQUN

Not yet recruiting

Irinotecan Liposomes in Combination With Nituzumab for the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of First-Line or Higher Immunotherapy

Nasopharyngeal Cancer

China
Tongji Hospital
Xinxiang Central Hospital

Not yet recruiting

Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment (EOEDSAAIBT)

Effect of Drug

China
Tianjin Medical University Cancer Institute and...

Recruiting

Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure

HCC

China
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
University of Zurich
Swiss HIV Cohort Study

Recruiting

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures

HIV Infections

Switzerland
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

Heart Failure | Decompensated Heart Failure
OHSU Knight Cancer Institute
Oregon Health and Science University

Not yet recruiting

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States

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