Search clinical trials for: Treatment resistant

Total 65986 results

Henan Cancer Hospital
Kingbio Medical (Beijing) Co., Ltd.

Recruiting

Patient-derived Organoid Drug Sensitivity Guided Treatment for Drug-resistant Recurrent Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Unity Health Toronto
University of Toronto

Not yet recruiting

Physical Activity Program for TRD

Major Depressive Disorder | Treatment-resistant Depression

Canada
Zydus Lifesciences Limited

Recruiting

A Study to Evaluate the Efficacy and Safety of ZYIL1 Oral Capsules for the Treatment of Patients With Mild to Moderately Active Ulcerative Colitis Resistant or Intolerant to Oral Aminosalicylates

Ulcerative Colitis

India
University of California, San Diego

Recruiting

Mindfulness Engaged Neurostimulation for Depression (MEND)

Depressive Disorder | Depression | Major Depressive Disorder | Treatment Resistant Depression

United States
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Centre Hospitalier du Rouvray
University Hospital, Rouen; Centre Hospitalier Sainte Anne, Paris

Not yet recruiting

Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant Depression (STIMAGNECT2)

Major Depressive Disorder
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
University Hospital, Ghent
Filament Health

Recruiting

Psilocybin for Hospitalized Patients With Treatment-resistant Depression (PSIHOS-D)

Treatment Resistant Depression

Belgium
Tri-Service General Hospital

Recruiting

Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients: A Randomized, Sham-controlled Trial

Major Depressive Disorder | Treatment-Resistant Depression | Suicide Ideations

Taiwan
Centre for Addiction and Mental Health
University Health Network, Toronto

Not yet recruiting

Theta-Burst Stimulation for Bipolar Depression (TRIBE)

Bipolar Disorder | Bipolar Depression | Treatment- Resistant Bipolar Disorder | Type 2 Bipolar Disorder

Canada
Centre Hospitalier St Anne

Not yet recruiting

Reduction of Auditory-Verbal Hallucinations in Schizophrenia Through Cortical Neuromodulation (HALLUSTIM)

Treatment Resistant Schizophrenia
Xuanwu Hospital, Beijing

Not yet recruiting

DBS for Treatment-resistant Obsessive-compulsive Disorder

Obsessive-Compulsive Disorder (OCD)

China
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Prostatic Neoplasms, Castration-Resistant

Israel, Taiwan
University of California, Los Angeles

Not yet recruiting

MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents

Psychotherapy | Adolescents | PTSD, Post Traumatic Stress Disorder

United States
Changping Laboratory

Recruiting

pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression

Major Depressive Disorder | Treatment Resistant Depression

China
University Health Network, Toronto
Centre for Addiction and Mental Health

Recruiting

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin (PSI-1V2)

Depression | Mood Disorders | Major Depressive Disorder | Treatment-Resistant Depression

Canada
Synergia Medical

Not yet recruiting

A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl (AURORA)

Drug Resistant Epilepsy
National Cheng-Kung University Hospital

Not yet recruiting

Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate

Schizophrenia | Schizo Affective Disorder | Symptom, Cognitive
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
Zhen-Yu Ding

Recruiting

DC Combined With ICIs in the Treatment of Advanced Lung Cancer Resistant to ICIs

Lung Cancer

China
University of Utah

Recruiting

Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis

Multiple Sclerosis | Major Depressive Disorder | Treatment Resistant Depression

United States
Ontario Shores Centre for Mental Health Sciences
Sunnybrook Health Sciences Centre

Recruiting

Accelerated Bilateral Sequential Theta Burst Stimulation in Older Adults With Treatment-resistant Depression (CogniTReaD)

Depressive Disorder, Treatment-Resistant

Canada
University of North Carolina, Chapel Hill
Foundation of Hope, North Carolina

Recruiting

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

Treatment Resistant Depression | Refractory Depression

United States
Centre for Addiction and Mental Health

Not yet recruiting

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD (PAP-OCD)

Obsessive-Compulsive Disorder
Amsterdam UMC, location VUmc
University of Amsterdam; Maastricht University; ZonMw: The Netherlands Organisation... and other collaborators

Not yet recruiting

Schema Therapy for Treatment-resistant Anxiety Disorders (PaDoLA)

Anxiety Disorders
ReCor Medical, Inc.

Not yet recruiting

Global Paradise System US Post Approval Study (US GPS)

Cardiovascular Diseases | Vascular Diseases | Hypertension
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Not yet recruiting

Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
First Affiliated Hospital of Chengdu Medical College

Not yet recruiting

Effectiveness and Safety of BiSAAE for Resistant Hypertension.

Resistant Hypertension
The George Institute
The University of New South Wales

Not yet recruiting

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression (TREK)

Treatment Resistant Depression

Australia
UNICANCER
Bayer

Not yet recruiting

Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastases Detected by Functional Imaging (PEACE8)

Prostatic Cancer, Castration-Resistant
Dr. Rafael Freire

Recruiting

Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study

Generalized Anxiety Disorder

Canada
King's College London
South London and Maudsley NHS Foundation Trust

Recruiting

The Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant Schizophrenia (RESTORE)

Treatment-resistant Schizophrenia | Healthy Controls | Treatment-responsive Schizophrenia

United Kingdom
University of Manitoba
Duke University

Recruiting

Lemborexant Treatment of Insomnia Linked to Epilepsy (L'ÉTOILE)

Epilepsy | Sleep

Canada
Changping Laboratory

Not yet recruiting

pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression

Major Depressive Disorder | Treatment Resistant Depression | MDD
Bradley Lega

Recruiting

Deep Brain Stimulation for Psychosis

Treatment-Refractory Schizophrenia

United States
Pengyuan Liu

Recruiting

Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer (CRPC)

China
Fred Hutchinson Cancer Center
PromiCell Therapeutics, Inc.

Not yet recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Mayo Clinic

Not yet recruiting

Transcranial Direct Current Stimulation (tDCS) as an Adjunctive Treatment for Treatment Resistant Depression (TRD)

Treatment Resistant Depression

United States
University of Colorado, Denver

Not yet recruiting

Psilocybin for Treatment-Resistant Depression

Anhedonia | Major Depressive Disorder | Treatment Resistant Depression

United States
Hua Li

Recruiting

Clinical Study of Individualized Treatment of Relapsed or Drug-resistant Advanced Gynecological Tumors Guided by PTC Model

Personalized Cancer Treatment

China
RemeGen Co., Ltd.

Recruiting

Disitamab Vedotin in the Treatment With HER2- Expression, Subjects With Locally Advanced or Metastatic Castration-resistant Prostate Cancer

Castration-resistant Prostate Cancer

China
Queen's University

Not yet recruiting

Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study

Generalized Anxiety Disorder

Canada
Jonsson Comprehensive Cancer Center

Not yet recruiting

Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)

Prostate Carcinoma | Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
Sichuan Provincial People's Hospital

Not yet recruiting

Precise Treatment of Ceftazidime-Avibactam in Patients With CRO Infections Under the Guidance of TDM and PPK Model

ECMO | Carbapenem-Resistant Enterobacteriaceae Infection
Liu Huang

Recruiting

Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer

Stomach Cancer | Breast Cancer | Pancreatic Adenocarcinoma | Lung Cancer | Cholangiocarcinoma | Esophageal Carcinoma

China
Mayo Clinic

Recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial for the Treatment of Carbapenem Resistant Gram-negative Bacterial Infection With Colistimethate Sodium for Injection

Mental Health Issue

China
Xuanwu Hospital, Beijing
Tianjin Anding Hospital; Ningcheng Center Hospital; Changning Mental Health Center and other collaborators

Not yet recruiting

Transcranial Alternating Current Stimulation for Treatment-Resistant Depression

Treatment-Resistant Depression
Changping Laboratory
Xianyue Hospital, Xiamen; Hebei Mental Health Center, Baoding; HuiLongGuan Hospital... and other collaborators

Recruiting

Stanford Neuromodulation Therapy (SNT) for the Treatment-Resistant Depression

Treatment Resistant Depression

China

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