Search clinical trials for: Umbrella study

Total 118677 results

University Health Network, Toronto

Recruiting

Umbrella Study for Single Patient Treatments in Oncology (UNIQUE)

Advanced Cancer | Rare Diseases

Canada
Pfizer
Arvinas Estrogen Receptor, Inc.; Carrick Therapeutics Limited

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Breast Cancer

United States, Belgium, Puerto Rico
Universitaire Ziekenhuizen KU Leuven
Innovative Medicines Initiative; BELpREG

Recruiting

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk (UmbrelLACT)

Breast Feeding | Human Milk

Belgium
Tempus AI

Recruiting

Umbrella Study for Analysis of Data Related to Patients With Cancer (Polaris)

Cancer

United States
Fudan University

Recruiting

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Advanced Salivary Gland Carcinoma

China
Hoffmann-La Roche

Recruiting

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study (UmbrellaMAX)

Cancer

Korea, Republic of, United Kingdom, Japan, Costa Rica, Thailand, Belgium, Taiwan, Russian Federation, Mexico, Poland, France
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)

Breast Cancer

United States, Canada, Spain, Italy
Stemline Therapeutics, Inc.

Recruiting

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer (ELEVATE)

Breast Cancer | Metastatic Breast Cancer

United States
Ruijin Hospital

Recruiting

A Umbrella Study in R/R PTCL Guided by Molecular Subtypes

Peripheral T Cell Lymphoma

China
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)

Breast Cancer

United States, Canada, Spain, Italy
Yonsei University

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Tislelizumab in Combination With Zanidatamab as a 2nd Line in HER2-Positive Advanced Gastric Cancer in K-Umbrella Trial

HER2-positive Gastric Cancer

Korea, Republic of
Pfizer

Recruiting

MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma

Multiple Myeloma

United States, Canada
University of British Columbia
University Health Network, Toronto; Janssen Inc.

Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer (GUNS)

Prostate Cancer

Canada, United States
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Fudan University

Recruiting

Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer (MULAN)

Breast Cancer | Metastatic Cancer

China
Merck Sharp & Dohme LLC

Recruiting

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

Carcinoma, Non-Small-Cell Lung

Poland, United States, Hungary, Israel, Italy, Korea, Republic of, Spain
Fudan University

Recruiting

FUSCC Refractory TNBC Umbrella (FUTURE) (FUTURE)

Triple-negative Breast Cancer

China
Yonsei University
Samsung Medical Center; AstraZeneca; Seoul National University Hospital; Korean... and other collaborators

Recruiting

An uMbrella Study of BIomarker-driven Targeted Therapy In Patients With Platinum-resistant Recurrent OvariaN Cancer(AMBITION)

Platinum-resistant Recurrent Ovarian Cancer

Korea, Republic of
Guangdong Association of Clinical Trials
Chinese Thoracic Oncology Group

Recruiting

Phase II Umbrella Study Directed by Next Generation Sequencing (TRUMP)

Carcinoma, Non-Small-Cell Lung

China
Samsung Medical Center

Recruiting

The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]

Neuroendocrine Carcinoma | Small Cell Lung Cancers

Korea, Republic of
Seoul National University Hospital

Active, not recruiting

DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer

Bile Duct Cancer | Chemotherapy Effect

Korea, Republic of
Hoffmann-La Roche

Active, not recruiting

An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma

Gastric and Gastroesophageal Junction Carcinoma

China
AstraZeneca

Active, not recruiting

Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy (HUDSON)

Non-Small Cell Lung Cancer

France, Spain, United States, Canada, Korea, Republic of, Austria, Israel, Germany
Incyte Corporation

Terminated

An Umbrella Study to Determine the Safety and Efficacy of Various Monotherapy or Combination Therapies in Neoadjuvant Urothelial Carcinoma (Optimus)

Urothelial Carcinoma

United States, France, Italy
Actelion

Completed

A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. (UMBRELLA)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Belgium, France, Poland, Russian Federation, Belarus, Turkey, Ukraine
Seoul National University Hospital
Chungnam National University Hospital; Korean Cancer Study Group

Completed

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

Head and Neck Neoplasms | HNSCC

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Umbrella Study for HIV Infected Adults Enrolled in NIAID-Funded Interleukin-2 Studies

HIV Infections

United States
M.D. Anderson Cancer Center
National Center for Research Resources (NCRR)

Unknown

Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial, An Umbrella Protocol

Advanced Cancers

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); European Foundation for the...

Unknown

Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Coronary Heart Disease

Canada
Seoul National University Hospital

Unknown

A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy

Head and Neck Neoplasms | HNSCC

Korea, Republic of
Dr. Gaines W. Hammond Jr. MD FACS

Unknown

A Prospective Evaluation of the Catheter Science C3 "Umbrella Catheter."

Urinary Retention | Urinary Bladder, Neurogenic | Intermittent Catheterization

United States
M.D. Anderson Cancer Center

Completed

An Umbrella, Modular Study Based on Epidermal Growth Factor Receptor (EGFR) Mutation Status

Advanced Cancers

United States
University of Alberta
University of Calgary

Not yet recruiting

PAUSE: Sick Day Medication Management Mobile App Study (PAUSE)

Adverse Event | Chronic Condition
Centrum Clinic IVF Center

Not yet recruiting

BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study) (BEST)

Fertilization | Fertilization in Vitro | Mature Oocyte Yield
Foundation University Islamabad

Not yet recruiting

Rate of Canine Retraction and Pain Perception Following Micro-osteoperforation- a Split Mouth Clinical Study (MOPS)

Pain | Rate of Canine Retraction

Pakistan
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Not yet recruiting

A Clinical Study of TQH2929 Injection in Treatment With Generalized Pustular Psoriasis (GPP)

Generalized Pustular Psoriasis

China
Instituto de Investigación Sanitaria Aragón

Not yet recruiting

Study on the Effectiveness and Differential Usability of the UP in Spanish University Students

UP in Online Group Format | UP in Blended Format (Online Group + UP App)

Spain
Walailak University

Not yet recruiting

Comparative Study of Decellularized Human Amniotic Membrane Hydrogel and Inverted Internal Limiting Membrane Flap in Idiopathic Large Macular Holes (MACROHOLE)

Macular Holes
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Fudan University
Shenzhen Maternity & Child Healthcare Hospital

Not yet recruiting

A Study of the Intervention of Time-restricted Eating in High-risk Populations of GDM

Dietary Habits | Gestational Diabetes Mellitus | Lifestyle Intervention | Randomized Controlled Study
MTI Biotech Inc
Vanderbilt University Medical Center

Not yet recruiting

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients (2-HOBA)

Alzheimer Disease | Mild Cognitive Impairment

United States
University of Washington

Not yet recruiting

E-Socket, Diagnostic Monitoring

Trans-Tibial Amputation
Karl Landsteiner University of Health Sciences
University Hospital St. Pölten

Recruiting

hepatomiR cACLD Study

Portal Hypertension | Chronic Liver Disease | Chronic Liver Disease and Cirrhosis

Austria
Weill Medical College of Cornell University

Not yet recruiting

Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study

Gut Microbiome | Dietary Supplement | Gut Health | L-Phenylalanine | Phenylpropionic Acid

United States
University Hospital, Toulouse

Not yet recruiting

Study of Cellular Heterogeneity in Patients With Mastocytosis (MastCellHet)

Mastocytosis

France
Centre Hospitalier Régional Metz-Thionville

Not yet recruiting

Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents (NEUROMUTE)

Psychiatric Disorder

France
Novartis Pharmaceuticals

Not yet recruiting

Prospective Observational Study to Evaluate Secukinumab Treatment Effectiveness in Pediatric Patients With Active Juvenile Enthesitis-related or Psoriatic Arthritis (Toddler)

Juvenile Idiopathic Arthritis
AstraZeneca

Not yet recruiting

Positron Emission Tomography Study of Changes in [11C]AZ14132516 Uptake Following Administration of AZD7798 to Patients With Crohn's Disease.

Crohn Disease

Sweden
Firalis SA

Recruiting

A Prospective, Monocentric Clinical Study for the Validation of in Vitro Diagnostic Tests Developed by Firalis (ApoDiag)

Genetic Health Risks

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study of Fecal Microbiota Transplantation (FMT) in Severe IBS Patients (ICEBOAT)

Irritable Bowel Syndrome

France

Search clinical trials for: Umbrella study

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