Search clinical trials for: Unknown Primary Cancer

Total 98698 results

Genelux Corporation
GOG Foundation

Recruiting

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (OnPrime, GOG-3076)

Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Platinum-refractory Ovarian Cancer | Primary Peritoneal Cancer | High-grade Serous Ovarian Cancer | Endometrioid Ovarian Cancer | Ovarian Clear Cell Carcinoma

United States
Telios Pharma, Inc.

Recruiting

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

Primary Myelofibrosis | Myelofibrosis | Post-PV MF | Post-ET Myelofibrosis

Spain, United States, France, Poland, Italy, Germany
University Hospital, Ghent
University Ghent; Kom Op Tegen Kanker

Recruiting

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer (PIPAC-NAL-IRI)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Bowel Cancer | Bile Duct Cancer | Peritoneal Carcinomatosis | Peritoneal Metastases | Appendix Cancer

Belgium
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Ralph NULL Salloum
Children's Hospital Medical Center, Cincinnati

Recruiting

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

High Grade Glioma | Medulloblastoma | Meningioma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary... and other conditions

United States
TILT Biotherapeutics Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Ovarian Cancer (PROTA)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Refractory Fallopian Tube Carcinoma | Platinum-Refractory Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma | Platinum-Sensitive Ovarian... and other conditions

United States, Finland
Cardiovascular and Interventional Radiological...

Recruiting

Registry on Percutaneous Electrochemotherapy (RESPECT)

Primary Liver Cancer | Secondary Liver Cancer

Germany
Aulos Bioscience, Inc.

Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Solid Tumor

Australia, United States
Changhai Hospital

Recruiting

Endotherapy for Painless Chronic Pancreatitis (EACH)

Abdominal Pain | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency | Cholangiopancreatography, Endoscopic Retrograde

China
Ruijin Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Anlotinib Plus Chemotherapy as First-line Therapy for Gastrointestinal Tumor Patients With Unresectable Liver Metastasis (ALTER-G-001) (ALTER-G-001)

Gastrointestinal Tumors

China
European Organisation for Research and Treatment...

Recruiting

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Glioma | Ependymoma | Hemangiopericytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Germ Cell Tumor | Embryonal Tumor | Hemangioblastoma | Glioneuronal Tumor | Choroid Plexus Tumor | Pineal Tumors | Tumor of the Sellar Region | Pineal Tumor | Melanocytic Tumor of CNS

Spain
Seagen Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer (MOUNTAINEER-03)

Colorectal Neoplasms

United States, Canada, Italy, Argentina, United Kingdom, China, Japan, Belgium, France, Korea, Republic of, Spain, Taiwan, Brazil, Ireland, Netherlands, Australia, Slovakia, Chile, Poland, Norway, Switzerland, Austria, Germany, Portugal, Gree... and more
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma (RELATIVITY-069)

Lymphoma, Non-Hodgkin | Hodgkin Disease

United States, France, Netherlands, Australia, United Kingdom, Italy, Spain, Germany
The University of Hong Kong

Recruiting

The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases

Cardiovascular Diseases | Hypertension | Diabetes Mellitus | Cancer | Kidney Disease, Chronic | Noncommunicable Diseases | Chronic Respiratory Disease

China
Hospital Clinico Universitario de Santiago

Recruiting

Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic Cancer (DEPARA)

Pancreatic Exocrine Insufficiency | Pancreatic Neoplasm Malignant Head Primary

Spain
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Recruiting

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia (SCOPE-L)

High Risk Acute Myeloid Leukemia | Relapsed Adult AML | Primary Refractory Acute Myeloid Leukemia

United States
Incyte Corporation

Recruiting

Study of INCB123667 in Subjects With Advanced Solid Tumors

Solid Tumors

United States, Japan, France, Italy, United Kingdom, Netherlands, Switzerland
Shanghai Gynecologic Oncology Group
Fudan University

Not yet recruiting

Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

China
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Osteosarcoma | Metastatic Osteosarcoma | Metastatic Malignant Neoplasm in the Lung

United States, Canada, Puerto Rico, New Zealand, Australia, Saudi Arabia
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion (HAPLOTAB)

Myelodysplastic Syndromes | Primary Immunodeficiency Diseases | Hemoglobinopathies | Chronic Myeloid Leukemia | Cytopenia | Severe Aplastic Anemia | Bone Marrow Failure Syndrome | Acute Myeloid Leukemia in Remission | Hemophagocytic Lymphohistiocytoses | Acute Lymphoblastic Leukemia in Remission | Severe...

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Celldex Therapeutics

Recruiting

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Serous Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Recurrent Fallopian... and other conditions

United States
Campus Bio-Medico University

Recruiting

Breast Stereotactic Radiotherapy to Primary Tumors in Metastatic Patients (BoMB)

Stage IV Breast Cancer

Italy
Erasmus Medical Center
Leiden University Medical Center; Medical Center Haaglanden; Rijnstate Hospital; Maasstadziekenhu... and other collaborators

Recruiting

HIV Indicator Diseases in Hospital and Primary Care (#AwareHIV)

HIV Infections | Acquired Immunodeficiency Syndrome | Sexually Transmitted Diseases, Viral | Pneumonia | Psoriasis | Weight Loss | Thrombocytopenia | Leukopenia | Dermatitis, Seborrheic | Herpes Zoster | Lymphadenopathy | Uterine Cervical Dysplasia | Primary Health Care | Diarrhea Chronic | Candida Infection | Infectious... and other conditions

Netherlands
Peter MacCallum Cancer Centre, Australia

Recruiting

PRIME_LUNG: Primary Radiotherapy In MEtastatic Lung Cancer - A Pilot Study (PRIME_LUNG)

NSCLC

Australia
Takeda
Takeda Development Center Americas, Inc.

Recruiting

First-in-Human Study of TAK-280 in Participants With Unresectable Locally Advanced or Metastatic Cancer

Unresectable Locally Advanced or Metastatic Cancer

Spain, United States, Australia, Canada
University Hospital Southampton NHS Foundation...
The Leeds Teaching Hospitals NHS Trust; University of Southampton; Newcastle-upon-Tyne... and other collaborators

Recruiting

Reconstruction in Extended MArgin Cancer Surgery (REMACS)

Quality of Life | Surgery--Complications | Abdominal Cancer | Pelvic Cancer

United Kingdom
National Taiwan University Hospital

Recruiting

Primary Tumor Resection With EGFR TKI for Stage IV NSCLC

NSCLC Stage IV

Taiwan
Fudan University

Recruiting

Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer

Prostate Cancer

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers

Metastatic Cancer | Advanced Cancer

United States
Northwestern University
National Cancer Institute (NCI)

Recruiting

Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
IntraGel Therapeutics

Not yet recruiting

A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck Tumor

Head and Neck Cancer

Israel
K-Group, Beta, Inc., a wholly owned subsidiary...

Recruiting

A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Primary Peritoneal Carcinoma

United States, France
Shanghai Gynecologic Oncology Group
Fudan University

Not yet recruiting

Surgery Combined With Maintenance Targeted Therapy in the Treatment of Advanced Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

China
Sutro Biopharma, Inc.

Recruiting

A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Ovarian Carcinoma | Ovary Cancer | Primary Peritoneal Carcinoma

United States
Seagen Inc.

Recruiting

A Study of SGN-B7H4V in Advanced Solid Tumors

Carcinoma, Non-Small-Cell Lung | Adenoid Cystic Carcinoma | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Endometrial Neoplasms | Cholangiocarcinoma | Triple Negative Breast Neoplasms | Gallbladder Carcinoma | HER2 Negative Breast Neoplasms | Hormone Receptor Positive Breast Neoplasms

United States, Spain, Canada, United Kingdom, Germany, Italy
National Cancer Institute (NCI)

Recruiting

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

Gynecologic Cancer | Colorectal Neoplasms | Colorectal Cancer | Ovarian Neoplasms | Peritoneal Neoplasms | Ovarian Cancer | Peritoneal Carcinomatosis | Appendiceal Neoplasms | Appendiceal Cancer | Gynecologic Neoplasms

United States
Oslo University Hospital

Recruiting

Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers

Locally Advanced Pelvic Cancer That Require Pelvic Exenteration

Norway
Changhai Hospital

Recruiting

Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis

Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases

China
LLS PedAL Initiative, LLC
AbbVie; Roche-Genentech; Princess Maxima Center for Pediatric Oncology (European... and other collaborators

Recruiting

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States, Canada, Denmark, Spain, Belgium, Australia, France, New Zealand, Netherlands, Czechia, Norway, Switzerland, Austria, Portugal, Italy, Sweden, Israel
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Phase Ib Study of Primary Efficacy and Safety of IBI321 Monotherapy or Combination Therapy in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
2seventy bio

Recruiting

A Study of bbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)

Diffuse Large B Cell Lymphoma (DLBCL)

United States
Janssen Pharmaceutical K.K.

Recruiting

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Japan
Mansoura University

Recruiting

Can Four Weeks-check Cystoscopy and Urine Cytology After Primary Complete Resection of T1 Bladder Cancer Replace Repeat Biopsy?

Bladder Cancer

Egypt
Fudan University

Not yet recruiting

Value of ctDNA in the Treatment of Multiple Primary Cancers

Multiple Primary Cancers

China
Zhujiang Hospital

Recruiting

Indocyanine Green Molecular Fluorescence Imaging Technique Using in Diagnosis and Treatment of Primary Liver Cancer (ICGMFITinPLC)

Liver Cancer

China
Region Örebro County
Region Östergötland; Dalarna County Council, Sweden; Uppsala County Council,... and other collaborators

Recruiting

Accuracy and Predictive Values for Colorectal Cancer of Quantitative FIT in Symptomatic Patients in Primary Care

Colorectal Cancer

Sweden
Weprom

Not yet recruiting

Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy (SPACE2)

Leukemia, Myeloid, Acute | Metastatic Cancer | Cancer, Rectum | Myelodysplasia | Cancer, Breast | Myeloma | Leukemia, Lymphocytic, Acute | Cancer, Lung | Cancer Colon | Leukemia, Lymphocytic, Chronic | Cancer, Kidney | Cancer Pancreas | Cancer Prostate | Leukemia,Myeloid, Chronic | Cancer Ovaries

France
GRAIL, LLC

Recruiting

PATHFINDER 2: A Multi-Cancer Early Detection Study

Cancer | Early Detection of Cancer

United States, Canada
Zealand University Hospital
Perfusion Tech Aps

Recruiting

Quantitative ICG Fluorescence Angiography in Colorectal Surgery (QUANTICO)

Colorectal Cancer | Anastomotic Leak

Denmark
Peter MacCallum Cancer Centre, Australia
St Vincent's Hospital, Sydney

Recruiting

PSMA PET Additive Value for Prostate Cancer Diagnosis in Men With Negative/Equivocal MRI (PRIMARY2)

Prostate Cancer

Australia

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