Search clinical trials for: adenoviral vector

Total 2931 results

Virion Therapeutics

Recruiting

Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy

Chronic Hepatitis B

Hong Kong, New Zealand
Albert B. Sabin Vaccine Institute
Biomedical Advanced Research and Development Authority

Not yet recruiting

Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults

Ebola Sudan Virus Disease

Uganda, Kenya
Ankara City Hospital Bilkent
The Scientific and Technological Research Council of Turkey; MonitorCRO

Recruiting

Phase I Clinical Trial With New SARS-CoV-2 CoVacHGMix Type 5 Adenoviral Vector Vaccine

COVID-19

Turkey
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Safety, Tolerability and Immunogenicity of Gam-COVID-Vac Vaccine in a Nasal Spray (SPRAY)

COVID-19 | SARS-CoV-2 Acute Respiratory Disease
Universitair Ziekenhuis Brussel

Recruiting

SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the UZ Brussel Following COVID-19 Vaccination Using an Adenoviral Vector

Covid19 | SARS-CoV-2

Belgium
Eli Lilly and Company
Incyte Corporation

Recruiting

A Study of Baricitinib in Participants With Rheumatoid Arthritis (RA-BRANCH)

Rheumatoid Arthritis

United States
Akamis Bio

Recruiting

First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector (STAR)

Metastatic Cancer | Epithelial Tumor

United States
Albert B. Sabin Vaccine Institute
Biomedical Advanced Research and Development Authority

Active, not recruiting

Monovalent Chimpanzee Adenoviral-Vectored Marburg Virus Vaccine in Healthy Adults

Marburg Virus Disease

Uganda, Kenya
Herantis Pharma Plc.

Active, not recruiting

Clinical Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema (AdeLE) (AdeLE)

Secondary Lymphedema

Finland, Sweden
University of Oxford
GlaxoSmithKline; European Commission; Oxford University Hospitals NHS Trust; ReiThera...

Completed

Class II Invariant Chain HCV Vaccine Study

Hepatitis C

United Kingdom
Herantis Pharma Plc.

Terminated

A Phase I Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema

Secondary Lymphedema

Finland
Vaxart

Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers ((VXA-G1-1-NN))

Norovirus Infections

United States
Akamis Bio

Completed

First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody) (FORTITUDE)

Metastatic Cancer | Epithelial Tumor

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to an Adenoviral HIV-1 Vaccine in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Centers for Disease Control and Prevention; International AIDS Vaccine Initiative and other collaborators

Withdrawn

Safety and Effectiveness of an HIV DNA Vaccine Followed by an HIV Adenoviral Vector Vaccine for Prevention of HIV Infection in the Americas and Africa

HIV Infections
National Institute of Allergy and Infectious Diseases...
International AIDS Vaccine Initiative

Withdrawn

Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African Adults

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immune Response to a Recombinant Adenovirus HIV-1 Vaccine in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Terminated

Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With Men

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

HVTN Protocol 204 - A Phase II Clinical Trial to Evaluate the Safety and Immunogenicity of a Multiclade HIV-1 DNA Plasmid Vaccine, VRC-HIVDNA016-00-VP, Followed by a Multiclade Recombinant Adenoviral Vector HIV-1 Vaccine Boost, VRCHIVADV014-00-VP, in HIV-1 Uninfected Adult Participants

HIV Infections

United States, Brazil, Haiti, Jamaica, South Africa
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to a DNA HIV Vaccine Followed by an Adenoviral Vaccine Boost Given Three Different Ways to HIV Uninfected Adults

HIV Infections

United States, Peru
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to a DNA HIV Vaccine Followed By Boosting With One of Two Serotypes of Adenoviral Vector HIV Vaccine in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to Two Different HIV Vaccines, Each Followed by a Adenoviral Vaccine Boost, in HIV Uninfected Adults

HIV Infections

United States
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis

Pruritus | Prurigo Nodularis

Austria, Germany, Poland
CG Oncology, Inc.

Terminated

Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer (BOND)

Carcinoma in Situ | Transitional Cell Carcinoma | Bladder Cancer | Carcinoma in Situ Concurrent With Papillary Tumors

United States
Gamaleya Research Institute of Epidemiology and...
Government of the city of Moscow; CRO: Crocus Medical BV

Unknown

Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 (RESIST)

Covid19 Prevention

Russian Federation
Gamaleya Research Institute of Epidemiology and...
PDC-CRO

Unknown

A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE (SPUTNIK-UAE)

Covid19 | SARS-CoV Infection
Gamaleya Research Institute of Epidemiology and...
Russian Direct Investment Fund; CRO: iPharma

Unknown

Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 in Belarus

Covid19

Belarus
Gamaleya Research Institute of Epidemiology and...
Ministerio del Poder Popular para la Salud de la República Bolivariana de...

Unknown

Clinical Trial of the Immunogenicity, Safety, and Efficacy of the Gam-COVID-Vac Vaccine Against COVID-19 in Venezuela (VENEZUELA)

Covid19
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Study of HIV Adenoviral Vector Vaccine in Healthy Subjects Using Needle or Biojector Injection

HIV Infections

United States
Vaxart

Completed

Dose-Ranging Trial of Safety & Immunogenicity of an Oral Adenoviral-Vector Based RSV Vaccine (VXA-RSV-f)

Respiratory Syncytial Virus (RSV)

United States
Vaxart

Completed

Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine

Norovirus Gastroenteritis

United States
Clinica Universidad de Navarra, Universidad de...
Centro de Investigación Médica Aplicada (CIMA)

Terminated

Phase I-II Vaccination of Autologous Dendritic Cells Transduced With Adenoviral Vector Encoding NS3 in Hepatitis C Encoding NS3 in Hepatitis C

Hepatitis C, Chronic
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults

HIV Infections

United States
Singapore Clinical Research Institute
ClinDatrix, Inc.; MicroVAX, LLC

Unknown

Safety Study of Human MUC-1 (Mucin-1) Adenoviral Vector Vaccine for Immunotherapy of Epithelial Cancers (MUC-1)

Epithelial Cancers of the Lung, Breast, Ovary, Prostate and Colon

Singapore
Uppsala University
Uppsala University Hospital

Completed

Phase I/IIa AdCD40L Immunogene Therapy for Malignant Melanoma and Other Solid Tumors

Malignant Melanoma

Sweden
Lisa H. Butterfield, Ph.D.
National Cancer Institute (NCI)

Terminated

Immunization With AFP + GM CSF Plasmid Prime and AFP Adenoviral Vector Boost in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer | Cancer of Liver | Hepatoma | Hepatocellular Cancer | Hepatic Cancer | Liver Cell Carcinoma | Cancer, Hepatocellular | Liver Cancer, Adult | Liver Cell Carcinoma, Adult | Cancer of the Liver | Neoplasms, Liver | Hepatic Neoplasms | Neoplasms, Hepatic

United States
University of Pennsylvania

Terminated

Phase I Study of Adenoviral Vector Mediated Gene Transfer for Ornithine Transcarbamylase in Adults With Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
Alaunos Therapeutics

Completed

Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Cancer.

Breast Cancer Nos Metastatic Recurrent

United States
Clinica Universidad de Navarra, Universidad de...

Completed

TK-based Suicide Gene Therapy for Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Spain
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Vaccine Therapy in Treating Patients With Stage II, Stage IIIA, Stage IIIB, or Stage IVA Liver Cancer

Liver Cancer
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Research Alliance; Ontario Cancer Research Network

Completed

Adenovirus Encoding Rat HER-2 in Patients With Metastatic Breast Cancer (AdHER2.1)

Metastatic Breast Cancer | Recurrent Breast Cancer

Canada
Kamuzu University of Health Sciences
Boston University; Michigan State University; Ministry of Health, Malawi

Not yet recruiting

The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children

Malaria,Falciparum
Mahidol University

Not yet recruiting

Dengue Vaccine Hesitancy Among International Travelers

Vaccine Hesitancy
Bayer

Not yet recruiting

A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants

Soil-transmitted Helminth Infection | Onchocerciasis (River Blindness)
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Malaria Research and Training...

Not yet recruiting

Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali

Malaria,Falciparum
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Children's National Research Institute
Steven & Alexandra Cohen Foundation; Clinical Trials Network for Lyme and Other...

Recruiting

Navigating Pregnancy and Parenthood With Lyme Disease

Pregnancy Complications | Parenting | Tick-Borne Diseases | Lyme Disease | Chronic Lyme Disease | Tick-Borne Infections | Post Treatment Lyme Disease

United States
Essen Biotech

Not yet recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease (BAH243)

Sickle Cell Disease | Sickle-Cell Disease With Crisis

China
Rigshospitalet, Denmark

Recruiting

64Cu-DOTATATE-PET for Lyme Neuroborreliosis (DOTA-LYME)

Borrelia Burgdorferi Neuroborreliosis

Denmark
Takeda

Not yet recruiting

A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia (PRIME-Q)

Dengue Fever

Malaysia

Search clinical trials for: adenoviral vector

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