Search clinical trials for: adults who have congenital heart defects

Total 102845 results

Emory University

Terminated

Heart Failure in Adult Patients With a History of Congenital Heart Disease

Congenital Heart Defects

United States
Natera, Inc.

Completed

Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies (VANISH)

Trisomy 21 | Trisomy 18 | Trisomy 13 | Vanishing Twin

United States
Actelion
Canadian Heart Research Centre

Completed

Adult Congenital Heart Disease Registry (QuERI)

Pulmonary Arterial Hypertension

United States
Berto J Bouma

Unknown

Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery (BOCA)

Congenital Heart Disease

Netherlands
Emory University

Terminated

Hepatitis C in Adults Who Underwent Congenital Heart Surgery Before Screening

Congenital Heart Disease

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) (ROXI-CATH)

Venous Thromboembolism
Scripps Translational Science Institute

Recruiting

The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study

Congenital Heart Disease

United States
Tenaya Therapeutics
Johns Hopkins University; Mayo Clinic

Recruiting

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC (RIDGE-1)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States
Janssen Research & Development, LLC

Recruiting

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide (MonumenTAL-6)

Relapsed or Refractory Multiple Myeloma

Korea, Republic of, Italy, Germany, France, Japan, Israel, Belgium, Denmark, Sweden, Canada, Spain, Czechia, Poland, Australia, Netherlands, United Kingdom, India, China
Bayer
Janssen Research & Development, LLC

Not yet recruiting

An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure

Children | Congenital Heart Disease | Prevention of Venous Thromboembolism | Fontan Procedure

Japan
Centro Cardiologico Monzino
Federico II University; IRCCS Policlinico S. Donato; Università di Cagliari

Recruiting

Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET) (MANET)

Migraine Headache | PFO - Patent Foramen Ovale

Italy
Jamie Jackson
National Institute of Nursing Research (NINR)

Recruiting

Congenital Heart Disease Physical Activity Lifestyle Study V.2 (CHD-PALS V2)

Heart Defects, Congenital | Cardiovascular Disease Other

United States
Mezzion Pharma Co. Ltd

Recruiting

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2 (FUEL-2)

Single Ventricle Heart Disease

United States
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; St George's, University of... and other collaborators

Recruiting

Low QRS Voltages in Young Healthy Individuals and Athletes

Dilated Cardiomyopathy | Sudden Cardiac Death | Sudden Cardiac Death Due to Cardiac Arrhythmia | Sudden Cardiac Arrest | Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Left Ventricular Cardiomyopathy

United Kingdom
University of Alberta
Canadian Institutes of Health Research (CIHR)

Recruiting

Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions (EMPOwer)

Heart Failure | Cancer | Chronic Kidney Diseases | Cirrhosis, Liver | Primary Biliary Cholangitis | Digestive Diseases | Women Who Have Experienced a Cardiac Event | Post-Transplant | Other Chronic Physical Condition

Canada
Hacettepe University

Recruiting

Investigation of Adults With Congenital Heart Disease in the Scope of the ICF

Quality of Life | Congenital Heart Disease | ICF

Turkey
Novo Nordisk A/S

Recruiting

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9 (REAL 9)

Turner Syndrome | Noonan Syndrome | SGA | ISS

Korea, Republic of, Malaysia, Netherlands, Spain, Poland, United States
IRCCS Policlinico S. Donato

Recruiting

Cardiovascular Magnetic Resonance in Adults With SysTemic Right Ventricle (STAR) (STAR)

Transposition of Great Arteries

Italy
Sanofi

Recruiting

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Plasma Cell Myeloma

Czechia, Australia, Chile, France, Spain, United States, Brazil, China, Greece, Japan, Korea, Republic of, Sweden, Taiwan, Finland, Italy, Russian Federation
KU Leuven
Hasselt University; University Hospital, Ghent

Recruiting

Accelerated Aging in Newborns and Adults With Congenital Heart Disease (AccelerAGE)

Heart Defects, Congenital

Belgium
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
Umeå University

Recruiting

Effect of Muscle Strengthening Training in Adults With Fontan Circulation

Congenital Heart Disease | Univentricular Heart

Sweden
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France; W.L.Gore & Associates; Abbott; Centre Hospitalier St... and other collaborators

Not yet recruiting

PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years (CLOSE-2)

Patent Foramen Ovale | Cryptogenic Ischemic Stroke

France
Nantes University Hospital
Inserm UMR1087, CNRS UMR6291; Clinique des Données, CIC 1413, CHU Nantes; CIC-FEA...

Recruiting

Genetics of Ventriculo-arterial Discordance (PreciPed)

Heart Defects, Congenital

France
Novo Nordisk A/S

Recruiting

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow (REAL 8)

SGA, Turner Syndrome, Noonan Syndrome, ISS

Belgium, Korea, Republic of, United States, Ireland, Malaysia, United Kingdom, Finland, France, Netherlands, Italy, Thailand, China, Japan, Portugal, Israel, Brazil, Greece, India, Mexico, Bulgaria, Serbia, Lithuania, Austria, Canada, C... and more
Boston Children's Hospital

Recruiting

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

Congenital Heart Disease

United States
Janssen Research & Development, LLC

Recruiting

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)

Multiple Myeloma

United States, Korea, Republic of, Denmark, Czechia, Israel, Switzerland, Belgium, United Kingdom, Japan, Argentina, Sweden, Canada, Spain, Germany, Netherlands, France, Brazil, Greece, Poland, Ireland, Hungary, Portugal, Australia, F... and more
National Cancer Institute (NCI)

Recruiting

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | Capillary Arteriovenous Malformation Syndrome | RASopathy

United States
University of North Carolina, Chapel Hill
The Hospital for Sick Children; Washington University School of Medicine; McGill... and other collaborators

Recruiting

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

Primary Ciliary Dyskinesia | Kartagener Syndrome | Primary Immune Deficiency

United States, Canada
University Hospital, Strasbourg, France

Recruiting

Health-related Quality of Life in Adults After Veno-arterial Extra-Corporeal Membrane Oxygenation Which is a Salvage Therapy Used in Patients With Severe Respiratory or Cardiac Failure Who Have Not Responded to Maximal Conventional Medical Therapy

Health Related Quality of Life | Veno-arterial Extra-Corporeal Membrane Oxygenation

France
atHeart Medical

Recruiting

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD (ASCENT ASD)

Heart Diseases | Cardiovascular Diseases | Congenital Abnormalities | Heart Septal Defects, Atrial | Heart Defects, Congenital | Cardiovascular Abnormalities | Heart Septal Defect

United States, France
University of Alberta
University of British Columbia; McGill University; Oregon Health and Science... and other collaborators

Recruiting

The Impact of an Innovative eHealth Transition Intervention on Self-Management Skills Among Young Adults With Congenital Heart Disease (READYorNot CHD)

Congenital Heart Disease | Congenital Heart Disease in Adolescence

Canada
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
National Cancer Institute (NCI)

Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Down Syndrome | B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States, Puerto Rico, Australia, Canada, New Zealand
W.L.Gore & Associates

Recruiting

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study (REDUCE PAS)

Stroke | PFO - Patent Foramen Ovale

United States
Maastricht University Medical Center
Netherlands Heart Foundation

Recruiting

Worm Study: Modifier Genes in Sudden Cardiac Death

Brugada Syndrome | Long QT Syndrome 3

Netherlands
Lawson Health Research Institute
Lauren Faught; Michael Greff; Michael Rieder; Safieddin Safavi-Naeini

Not yet recruiting

The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS

Obesity | Fever | Congenital Heart Disease | COPD | Respiratory Distress

Canada
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Autoimmune Diseases | Hodgkin Lymphoma | Hematologic Malignancies | Acute Lymphoblastic Leukemia (ALL) | Non-hodgkin Lymphoma | Severe Aplastic Anemia | Inherited Disorders of Metabolism | Inherited Abnormalities of Platelets | Histiocytic Disorders | Acute Myelogenous Leukemia (AML or ANLL) | Other Acute... and other conditions

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) (CHD GENES)

Congenital Heart Defects

United States, United Kingdom
Nationwide Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Genetics of Congenital Heart Disease

Congenital Heart Disease

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

DiGeorge Syndrome | 22q11.2 Deletion Syndrome

United States
Medtronic Cardiovascular

Active, not recruiting

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Bicuspid Aortic Valve

United States
W.L.Gore & Associates

Active, not recruiting

GORE® CARDIOFORM Septal Occluder Migraine Clinical Study (RELIEF)

Migraine | Patent Foramen Ovale | PFO - Patent Foramen Ovale

United States
Bristol-Myers Squibb
AbbVie

Active, not recruiting

Continuing Treatment for Participants Who Have Participated in a Prior Protocol Investigating Elotuzumab

Multiple Myeloma

United States, Canada, Australia, Poland, Italy, Belgium, Spain, Japan, Greece, Hungary, Romania, Turkey, United Kingdom
Pfizer
Pfizer

Available

Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options

Sickle Cell Disease

United States, Brazil
Duke University
Adult Congenital Heart Association

Active, not recruiting

Peer Coaching Intervention in Young Adults With Congenital Heart Disease (CHASM in ACHD)

Congenital Heart Disease | Congenital Heart Defect

United States
Bristol-Myers Squibb

Active, not recruiting

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Hypertrophic Cardiomyopathy | Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

Denmark, United States, Belgium, Czechia, France, Germany, Israel, Italy, Netherlands, Poland, Portugal, Spain, United Kingdom
Abbott Medical Devices

Active, not recruiting

Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study (VPA)

Ventricular Septal Defects

United States, Canada
Medtronic Heart Valves

Active, not recruiting

The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study

Congenital Heart Disease | Pulmonary Regurgitation | Tetrology of Fallot | RVOT Anomaly

United States, Canada, Japan
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Acute Lymphoblastic Leukemia | Down Syndrome | Philadelphia Chromosome Positive | Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Childhood B Acute Lymphoblastic Leukemia | Adult B Lymphoblastic Lymphoma | Ann Arbor Stage I B Lymphoblastic Lymphoma | Ann Arbor Stage... and other conditions

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland

Search clinical trials for: adults who have congenital heart defects

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