Search clinical trials for: als clinical trials

Total 68195 results

University of Cologne
The Clinical Trials Centre Cologne; ESCRS (European Society of Cataract and...

Not yet recruiting

Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy

Cataract Surgery | Cataract and Fuchs Endothelial Corneal Dystrophy

Denmark, Germany, Netherlands, Spain
GlaxoSmithKline

Recruiting

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

Respiratory Syncytial Virus Infections

United States, Canada, Japan, Germany, Australia, South Africa
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
Atea Pharmaceuticals, Inc.

Recruiting

Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir

Healthy Volunteer Study

United States
Resurge Therapeutics Inc.

Recruiting

RT-310 Dose Escalation BPH Study

Lower Urinary Tract Symptoms | BPH (Benign Prostatic Hyperplasia)

New Zealand, Australia
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Prostatic Neoplasms | Metastatic Castration-resistant Prostate Cancer (mCRPC)

Australia, Germany, United States, Puerto Rico, Israel, Korea, Republic of, Taiwan, China, Costa Rica, Guatemala, Spain, France, Hong Kong, Portugal, Romania, Chile, Czechia, Hungary, Italy, Sweden, Turkey, United Kingdom, Estonia, Ir... and more
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Prostate Cancer Metastatic

Canada, Germany, United States, Israel, Puerto Rico, Taiwan, Korea, Republic of, Australia, Chile, China, France, Norway, Czechia, Finland, Hong Kong, Netherlands, Poland, Spain, Sweden, Turkey, Denmark, Hungary, Italy, United Kingdom, ... and more
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY3537982 Plus Immunotherapy With or Without Chemotherapy in Participants With Non-Small Cell Lung Cancer (NSCLC) With a Change in a Gene Called KRAS G12C (SUNRAY-01)

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis

United States, Taiwan, Belgium, Australia, Japan, United Kingdom, Spain, China, France, Germany, Austria, Korea, Republic of, Hungary, Switzerland, Mexico, Norway, Italy, Turkey, Portugal, Netherlands, Greece, India, Romania, Canada, De... and more
Allegheny Singer Research Institute (also known...

Recruiting

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

Breast Cancer | Breast Cancer Female | Breast Carcinoma in Situ

United States
Pfizer

Recruiting

A Study to Learn About the Amount of the Study Medicine (Sisunatovir) in Blood and Its Safety in Infants and Children With Pneumonia Caused by RSV

Respiratory Syncytial Virus Infections

United States, Israel, Japan, Korea, Republic of, South Africa, Argentina, Canada
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Study of V940 Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) (INTerpath-002)

Non-small Cell Lung Cancer

United States, New Zealand, Australia, Costa Rica, Taiwan, Argentina, France, Chile, Hungary, Spain, Greece, Poland, Canada, Lithuania, Norway, Italy, Czechia
Boehringer Ingelheim

Recruiting

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight (SYNCHRONIZE™-2)

Obesity | Diabetes Mellitus, Type 2

United States, Korea, Republic of, Australia, Spain, Belgium, China, Hungary, Canada, United Kingdom, Japan, Czechia, Poland, Greece, New Zealand, Denmark, Finland, Germany, Netherlands, Sweden
Bayer

Recruiting

A Study to Learn How Safe the Study Treatment BAY2701250 is, How it Affects the Body and How it Moves Into, Through and Out of the Body in Healthy Male Participants When a Single Amount is Given as an Injection Into the Vein (Intravenous Infusion) or Under the Skin (Subcutaneous Injection)

Pulmonary Hypertension Due to Left Heart Disease

Germany
Allegheny Singer Research Institute (also known...

Recruiting

Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer (RIOT2)

Malignant Ascites | Malignant Pleural Effusion

United States
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion) (QUASAR)

Macular Edema Secondary to Retinal Vein Occlusion

Japan, Korea, Republic of, China, Israel, Lithuania, United States, Italy, Spain, Hungary, Portugal, Serbia, Poland, United Kingdom, Thailand, Czechia, Austria, Germany, Turkey, Australia, Bulgaria, Estonia, France, Georgia, Latvia, Mal... and more
IGLESIAS Juan Fernando
Clinical Trials Unit University of Bern

Not yet recruiting

STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT (STARS DAPT)

ST Elevation Myocardial Infarction

Switzerland
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (REPLENISH)

Polymyalgia Rheumatica

United States, Australia, Germany, Belgium, France, Spain, Italy, Lebanon, Switzerland, Japan, Israel, Denmark, Argentina, Netherlands, Colombia, Chile, Hungary, Poland, Turkey, Czechia, Brazil, South Africa, Mexico, Canada, United Kingdom
Hoth Therapeutics, Inc.
Worldwide Clinical Trials

Recruiting

Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors (CLEER)

Acneiform Eruption Due to Chemical | Xerosis Cutis | Paronychia

United States
Bristol-Myers Squibb

Recruiting

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE) (POETYK SLE-1)

Systemic Lupus Erythematosus

United States, Brazil, China, Germany, Italy, France, Mexico, Poland, Puerto Rico, Argentina, Canada, Colombia, Hong Kong, Peru, Romania, Portugal, Korea, Republic of, Turkey, Ireland, India, Lithuania, Bulgaria, Slovakia
Pfizer

Recruiting

A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo (Tranquillo)

Stable Nonsegmental Vitiligo | Active Nonsegmental Vitiligo

United States, Spain, Australia, Mexico, Canada, China, Japan, Italy, Turkey, Korea, Republic of, Germany, South Africa, Poland, United Kingdom, Bulgaria
GlaxoSmithKline

Recruiting

A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years

Hepatitis B

Germany, United Kingdom, Belgium
Power Life Sciences Inc.

Not yet recruiting

Clinical Trial - Analyzing Participation Experiences Of Amyotrophic Lateral Sclerosis Patients

Amyotrophic Lateral Sclerosis | ALS
Allegheny Singer Research Institute (also known...
Elekta Limited

Recruiting

A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases

Brain Metastases, Adult

United States
Joshua Rosenblat

Recruiting

Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression (KET-BD-Sustain)

Bipolar Disorder | Bipolar Depression | Bipolar I Disorder | Bipolar II Disorder

Canada
Disc Medicine, Inc

Recruiting

Study of DISC-0974 in Participants With Myelofibrosis and Anemia

Primary Myelofibrosis | Anemia | Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis | Myelofibrosis; Anemia | Myelofibrosis Due to and Following Polycythemia Vera

United States
John Lister
Miltenyi Biotec, Inc.; Lentigen Technology, Inc.; AHN (Allegheny Health Network)...

Recruiting

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | B Acute Lymphoblastic Leukemia | B-Cell Lymphoma | Transformed Lymphoma

United States
Allegheny Singer Research Institute (also known...
Johns Hopkins University

Recruiting

Home Biofeedback or Pelvic Floor Physical Therapy for Postpartum Urinary Incontinence.

Urinary Incontinence | Pelvic Floor Disorders

United States
Macquarie University, Australia
King's College London; Stichting TRICALS Foundation

Recruiting

Triumeq in Amyotrophic Lateral Sclerosis (LIGHTHOUSE II)

Amyotrophic Lateral Sclerosis

Spain, Australia, United Kingdom, New Zealand, Netherlands, Ireland, Slovenia, Sweden
Exact Sciences Corporation

Recruiting

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

Hepatitis B | Hepatocellular Carcinoma | Cirrhosis | Liver Cancer | Hepatocellular Cancer

United States
Pfizer

Recruiting

Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults. (RENOIR)

Lower Respiratory Tract Illness

United States, Argentina, Canada, Finland, Japan, Netherlands, South Africa
Vigil Neuroscience, Inc.

Recruiting

Natural History Study in Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia (ALSP)

ALSP

United States, Canada, Germany, Netherlands, United Kingdom, Brazil
Joshua Rosenblat

Recruiting

Ketamine for Treatment-Resistant Bipolar Disorder (KET-BD)

Bipolar Disorder | Bipolar Depression | Bipolar I Disorder | Bipolar II Disorder

Canada
Boston Scientific Corporation

Recruiting

REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men (VAPEUR RCT)

Benign Prostatic Hyperplasia (BPH)

France, Australia
Viveve Inc.

Recruiting

Prospective US Radiofrequency SUI Trial (PURSUIT)

Urinary Incontinence, Stress

United States
Allegheny Singer Research Institute (also known...
Johns Hopkins University

Recruiting

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

Urinary Retention Postoperative

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

HIV Infections | Tuberculosis

United States, Malawi, Puerto Rico, South Africa, Thailand, Zimbabwe, Brazil, Kenya, Uganda, India, Tanzania, Botswana
Eisai Inc.
National Institute on Aging (NIA); Biogen; Alzheimer's Clinical Trials Consortium

Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Preclinical Alzheimer's Disease | Early Preclinical Alzheimer's Disease

United States, Singapore, Canada, Spain, Australia, Japan, United Kingdom, Sweden, Netherlands
donald whiting
Boston Scientific Corporation

Recruiting

Deep Brain Stimulation Effects in Patients With Chronic Refractory Obesity

Obesity

United States
Allegheny Singer Research Institute (also known...
Abbott

Recruiting

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

Opioid-use Disorder

United States
AnGes USA, Inc.

Recruiting

Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers

Peripheral Artery Disease | Chronic Limb Threatening Ischemia | Ischaemic Ulcer of Lower Leg Due to Atherosclerotic Disease | Ischemic Ulcer of Foot

United States
Docbot, Inc.

Recruiting

To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age (AIDA)

Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp | Colorectal SSA

United States
Regeneron Pharmaceuticals
Sanofi

Recruiting

Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients

Hepatocellular Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States
West Penn Allegheny Health System

Recruiting

The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral Sling

Stress Urinary Incontinence

United States
Eli Lilly and Company

Recruiting

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

Ulcerative Colitis

China, Australia, Taiwan, United States, Switzerland, Moldova, Republic of, Japan, Malaysia, Korea, Republic of, Canada, Italy, Austria, Ukraine, Netherlands, Denmark, Israel, Czechia, Hungary, Poland, Serbia, United Kingdom, Spain, Indi... and more
Merck Sharp & Dohme LLC

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors | Hematologic Malignancies

United States, Poland, Brazil, Ukraine, Argentina, Australia, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic... and more
Cook MyoSite

Recruiting

Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence (CELLEBRATE)

Stress Urinary Incontinence

United States, United Kingdom
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

Breast Cancer

United States
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA-BRIDGE)

Rheumatoid Arthritis

Spain, United States, Hungary, Australia, Turkey, Czechia, Belgium, United Kingdom, Poland, Puerto Rico, Israel, Switzerland, France, South Africa, Romania, Italy, Germany, Netherlands, Austria, Denmark, Lithuania, Russian Federation and more

Search clinical trials for: als clinical trials

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