Search clinical trials for: alteplase

Total 168 results

Kafrelsheikh University

Recruiting

Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
Kristina Svennerholm
Karolinska University Hospital; Sunderby Hospital; University Hospital, Linkoeping and other collaborators

Recruiting

Mechanical Thrombectomy With the FlowTriever Device in Acute Pulmonary Embolism - a Retrospective Analysis

Pulmonary Embolism

Sweden
M.D. Anderson Cancer Center

Recruiting

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

ALteplase in Patients With LOW NIHSS and Specified Disabling Deficits (ALLOW)

Thrombosis

China
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
Dongzhimen Hospital, Beijing

Not yet recruiting

Outcomes After Intravenous Alteplase / Tenecteplase With or Without Shuxuetong Injection in Routine Clinical Practice

Ischemic Stroke, Acute
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Aspirin Combined With Clopidogrel Versus Intravenous Alteplase for Acute Minor Stroke (AGREE)

Ischemic Stroke

China
National University of Malaysia

Recruiting

Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic (PENTAD-FT)

Pleural Infection

Malaysia
Xuanwu Hospital, Beijing

Recruiting

Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)

Acute Ischemic Stroke | Arterial Thrombosis | Posterior Circulation Brain Infarction

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Hospital of Southern Medical University

Recruiting

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy (PEARL)

Stroke, Acute Ischemic

China
The First Affiliated Hospital of University of...

Recruiting

Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion

Basilar Artery Occlusion | Acute Cerebrovascular Accident | Stroke Due to Basilar Artery Occlusion

China
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica; Instituto de Salud Carlos III

Not yet recruiting

CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2). (CHOICE2)

Stroke, Acute | Stroke, Acute Ischemic

Spain
Chinese University of Hong Kong

Not yet recruiting

Comparison of Outcomes Between Low and Standard Dose Intrapleural tPA for Pleural Infection

Pleural Infection

Hong Kong
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Xinqiao Hospital of Chongqing
Zhejiang University

Recruiting

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke (ADJUVANT)

Stroke, Acute Ischemic

China
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France
Sichuan Academy of Medical Sciences
Sichuan Provincial People's Hospital

Recruiting

Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke (BEST-BAO)

Thrombosis | Acute Ischemic Stroke | Basilar Artery Occlusion | Endovascular Treatment | Alteplase

China
Hospital Universitari Vall d'Hebron Research Institute
Instituto de Salud Carlos III

Recruiting

Tenecteplase Compared to Alteplase for Patients With Large Vesel Oclusion Suspicion Before Thrombectomy

Acute Ischemic Stroke

Spain
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)

Pulmonary Embolism

United States
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Ege University

Recruiting

Reduced Dose Thrombolytic in Intermediate/High Risk Pulmonary Thromboembolism

Pulmonary Embolism

Turkey
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
Assiut University

Not yet recruiting

The Prevalence and Associated Factors of Early Deterioration After Successful Recanalization in Acute Ischemic Stroke

Acute Stroke
University Hospital Tuebingen

Recruiting

Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion (REVISION)

Central Retinal Artery Occlusion

Germany
University Hospital, Caen

Not yet recruiting

N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE (NAC-S)

Stroke, Ischemic

France
Xuanwu Hospital, Beijing

Recruiting

Combination of the Immune Modulator Dimethyl Fumarate With Alteplase in Acute Ischemic Stroke

Acute Ischemic Stroke

China
Second Affiliated Hospital, School of Medicine,...
Shaoxing People's Hospital; Huizhou Municipal Central Hospital; The Second Affiliated... and other collaborators

Recruiting

24 Hours Treatment With Alteplase in Patients With Ischemic Stroke

Stroke

China
Bin He

Recruiting

Changes of Cardiopulmonary Function After Thrombolysis in Patients With Pulmonary Embolism (CCFATAPE)

Acute Pulmonary Embolism

China
Second Affiliated Hospital, School of Medicine,...
Shaoxing People's Hospital; Huizhou Municipal Central Hospital; Taizhou Hospital and other collaborators

Recruiting

Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke

Stroke | Inflammation

China
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Assistance Publique - Hôpitaux de Paris
Canadian Institutes of Health Research (CIHR); Boehringer Ingelheim; Johannes... and other collaborators

Recruiting

Pulmonary Embolism International THrOmbolysis Study-3 (PEITHO-3)

Pulmonary Embolism

Netherlands, Spain, Belgium, Slovenia, France, Portugal, Austria, Canada, Poland, Switzerland, Germany, Italy, Romania, Serbia
Rigshospitalet, Denmark
University Hospital Bispebjerg and Frederiksberg; Hillerod Hospital, Denmark; Herlev and Gentofte Hospital and other collaborators

Recruiting

Low Dose Thrombolysis, Ultrasound Assisted Thrombolysis or Heparin for Intermediate High Risk Pulmonary Embolism (STRATIFY)

Pulmonary Embolism

Denmark
University of Aarhus

Recruiting

Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism (BETULA)

Pulmonary Embolism

Denmark
Vastra Gotaland Region

Recruiting

Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study (OPTIMAL)

ST-segment Elevation Myocardial Infarction

Sweden
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (TRISTARDS)

Acute Respiratory Distress Syndrome

Spain, Germany, Italy, Belgium, Mexico, Netherlands, India, France, Malaysia, Austria, Brazil, Russian Federation, Turkey
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
Angde Biotech Pharmaceutical Co., Ltd.
Beijing Tiantan Hospital

Completed

A Study of r-PA Treating Patients With Acute Ischemic Stroke（RAISE）

Acute Ischemic Stroke

China
Beijing Tiantan Hospital

Completed

Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-III (TRACE III)

Ischemic Stroke, Acute

China
Azienda U.S.L. 1 di Massa e Carrara

Withdrawn

Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism (MONALYSE)

Pulmonary Embolism
Nantes University Hospital

Completed

A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion (THEIA)

Central Retinal Artery Occlusion

France
Boehringer Ingelheim

Completed

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (ORIGINAL)

Stroke

China
Centre Hospitalier Sud Francilien

Completed

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study (DIVArétro)

Acute Ischemic Stroke Due to Medium-vessel-occlusion

France
Centre Hospitalier Sud Francilien

Completed

Tirofiban Plus Intravenous Thrombolysis in Acute Anterior Choroidal Infarction or Paramedian Pontine Infarction (TITACIPPI)

Acute Anterior Choroidal Infarction (ACI) | Paramedian Pontine Infarction (IPP)

France
University of Michigan
Genentech, Inc.

Completed

Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis (PLATyPuS)

Healthy | Protein-Losing Enteropathies | Plastic Bronchitis

United States
Dow University of Health Sciences

Completed

Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.

Apical Periodontitis | Irreversible Pulpitis | Root Canal Infection | Periapical Abscess

Pakistan

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