Search clinical trials for: amyloid load

Total 2811 results

Institut National de la Santé Et de la Recherche...

Not yet recruiting

Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study (INSIGHT-2)

Alzheimer Disease | Memory Disorders | Memory Complaint

France
New York State Psychiatric Institute
Bayer; National Institute on Aging (NIA)

Completed

Measuring Brain Amyloid Plaque Load in Older Adults Using BAY 94-9172

Late Onset Alzheimer Disease

United States
University Hospital, Toulouse
MSDAVENIR

Active, not recruiting

Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults (COGFRAIL)

Frail Elderly

France
University of Tennessee Graduate School of Medicine

Active, not recruiting

Repeat PET/CT Imaging of Patients With Amyloid 124I-AT-01 to Measure Changes in Organ-specific Amyloid Load

Systemic Amyloidosis

United States
University of California, San Francisco
National Institute on Aging (NIA)

Completed

Feasibility of Gamma Transcranial Alternating Current Stimulation to Reduce Beta-amyloid Load and Improve Memory

Mild Cognitive Impairment

United States
Chinese University of Hong Kong

Withdrawn

A Comparative Study of Brain Structure and Amyloid Load in MCI Patients

Mild Cognitive Impairment

Hong Kong
EIP Pharma Inc

Completed

A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD)

Mild Cognitive Impairment | Alzheimer's Disease

Netherlands
Genentech, Inc.

Completed

A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Spain, United States, France
University Hospital, Bordeaux
General Electric; Fondation Plan Alzheimer

Unknown

Amyloïd Load in Elderly Population: Effect of Cognitive Reserve (EDUMA)

Plaque, Amyloid | Cognitive Deficits

France
Institut National de la Santé Et de la Recherche...

Completed

Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease (BIOMAGE)

Logopenic Progressive Aphasia | Posterior Cortical Atrophy | Alzheimer's Disease

France
PepsiCo Global R&D

Recruiting

Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance

Exercise | Heart Rate Variability

United States
University Hospital, Basel, Switzerland

Not yet recruiting

Load Limits After Orthopaedic Surgery: Biofeedback vs. Conventional Method (AppPWB)

Surgery

Switzerland
Gérond'if

Not yet recruiting

Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure (ARNOLD)

Cardiac Amyloidosis

France
Leiden University Medical Center
The Dutch Brain Foundation (funding)

Not yet recruiting

Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy (Clear-Brain)

Cerebral Amyloid Angiopathy
Jeffrey Zonder

Not yet recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL) (FLORAL)

Renal AL Amyloidosis

United States
Peking University People's Hospital

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
AstraZeneca

Recruiting

Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia (LOCUS)

Carpal Tunnel Syndrome | Amyloidosis | Polyneuropathy | Hereditary Transthyretin Amyloidosis

Russian Federation
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
All India Institute of Medical Sciences, Bhubaneswar

Not yet recruiting

Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese Patients (USP)

Pneumoperitoneum | Morbid Obesity | Bariatric Surgery Candidate

India
University Hospital, Ghent

Recruiting

Amyloid PET in Patients With Mild Cognitive Impairment and Early Dementia

MCI

Belgium
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
NeuroVision Imaging

Recruiting

Effect of LEQEMBI on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment

United States
Alnylam Pharmaceuticals

Recruiting

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy (cAPPricorn-1)

Cerebral Amyloid Angiopathy

Canada
Pfizer

Not yet recruiting

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

United States
CentraCare

Recruiting

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness (PHOENIX)

Fluid Responsiveness

United States
Beni-Suef University

Recruiting

Efficacy of Voriconazole Loaded Spanlastics Gel Versus Clotriamazole Cream on Treating Vulvovaginal Candidasis

Treatment of Vagnial Cabdudasis

Egypt
State Key Laboratory of Respiratory Disease

Recruiting

Effect of CPAP on Respiratory Load in COPD

Chronic Obstructive Pulmonary Disease

China
University of Florida

Not yet recruiting

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

Recurrent Glioblastoma

United States
University of Mississippi Medical Center
University of Alabama at Birmingham

Recruiting

Low Systemic/High Local Exercise Load in Peds SCD

Sickle Cell Anemia in Children

United States
Washington University School of Medicine
Alzheimer's Association; Eisai Inc.

Not yet recruiting

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease (DIAN-TU)

Dementia | Alzheimer's Disease | Alzheimer's Disease, Familial

United States, Australia, United Kingdom
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
Minnesota HealthSolutions

Not yet recruiting

Safety-Enhancing Motor Vehicle Child Safety Seat

Safety Issues | Motor Vehicle Injury

United States
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
Documenting Hope Project

Recruiting

FLIGHT Study for Childhood Chronic Illness

Chronic Illnesses, Multiple

United States
Wingate Institute
Weizmann Institute of Science; Kaplan Medical Center; Ministry of Innovation,...

Recruiting

Identifying Periods of High Training Load Considering the Menstrual Cycle Phases in Elite and Non-elite Female Athletes

Physical Activity | Athletes | Menstrual Cycle

Israel
American Society of Clinical Oncology
Patient-Centered Outcomes Research Institute

Not yet recruiting

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

Metastatic Breast Cancer
Nanjing University School of Medicine

Recruiting

Daratumumab for Patients With Light Chain Amyloidosis

Light Chain (AL) Amyloidosis

China
Ain Shams University

Not yet recruiting

Occlusion and Disocclusion Time in Immediately Loaded Overdentures Supported by Two Splinted Versus Non Splinted Interforaminal Implants

Edentulous Jaw

Egypt
Cairo University

Not yet recruiting

Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation

Alveolar Bone Loss

Egypt
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Steen Hvitfeldt Poulsen

Recruiting

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy (DobAttrAS)

Aortic Stenosis | Transthyretin Amyloid Cardiomyopathy

Denmark
Institut Mutualiste Montsouris

Recruiting

Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO) (ATTR-ORTHO)

Carpal Tunnel Syndrome | Knee Prosthesis | ATTR Amyloidosis | Cardiopathy | Hip Prosthesis | Lumbar Spine Stenosis

France
AstraZeneca

Recruiting

hATTR Polyneuropathy in Russia (PRIMER)

Hereditary Transthyretin Amyloidosis

Russian Federation
Tufts Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

Smoldering Multiple Myeloma

United States
Fundació Eurecat
University Rovira i Virgili

Not yet recruiting

Association Between Training Load and Lactate and Other Metabolites Analyzed by Metabolomic and Proteomic Techniques (PROTEOMET)

Lactate | Metabolomics | Proteomics | Sports Performance

Spain
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety

Recruiting

Tele-Support for Emergency Medical Technicians (POHCA)

Cardiac Arrest

Austria
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Ruijin Hospital; China-Japan Friendship...

Recruiting

The Study of Monitoring and Dosing Guidance of Direct Oral Anticoagulants Based on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics

Pulmonary Embolism

China
Fujian Medical University

Recruiting

A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
AstraZeneca

Recruiting

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis (OverTTuRe)

ATTR Amyloidosis

United Kingdom, United States, Denmark, Japan

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