Search clinical trials for: assess optimal renoprotective dose of Aliskiren

Total 430544 results

Novartis

Completed

Study to Assess the Optimal Renoprotective Dose of Aliskiren in Hypertensive Patients With Type 2 Diabetes and Incipient or Overt Nephropathy

Diabetes Mellitus, Type 2

Denmark
Green Cross Wellbeing

Recruiting

Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups.

Chronic Liver Disease

Korea, Republic of
Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Healthy Volunteers | Influenza Immunization

United States
LG Life Sciences

Completed

Study to Assess the Effect on Recovery of GI Motility and Safety and to Determine the Optimal Dose of LD02GIFRO

Colon Resection | _large Interstinal Surgery

Korea, Republic of
Novartis

Completed

Effects of Aliskiren, Irbesartan, and the Combination in Hypertensive Patients With Type 2 Diabetes and Diabetic Nephropathy

Diabetes Type 2

Denmark
GE Healthcare
PPD; Fortrea

Not yet recruiting

A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers

Healthy Volunteers

United States
University of Chile
Agencia Nacional de Investigación y Desarrollo

Not yet recruiting

Optimal Therapeutic Dose of tDCS for Functional Upper Limb Recovery in People With Stroke

Stroke | Neurologic Deficits
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

Canada
Assistance Publique Hopitaux De Marseille

Recruiting

Prospective Multicenter Cohort Study to Validate Four Groups of Biomarkers for Assessing Lung Cancer Risk Among Patients With Atheromatous Cardiovascular Disease in a Screening Pathway (BIOCEPTION)

Lung Cancer | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 Years

France
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
Chestnut Health Systems
National Institute of Mental Health (NIMH)

Not yet recruiting

K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions (K-ORCA)

Child Abuse | Mental Health | Implementation Science | Decision Making | Family | Child Welfare | Decision Making, Shared | Social Facilitation | Policy | Decision Support Technique | Organizations | Consensus
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Sanofi Pasteur, a Sanofi Company

Recruiting

A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above

Influenza Immunization

United States, Puerto Rico
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
Azienda Ospedaliera Universitaria Integrata Verona
Abbott Medical Devices

Recruiting

Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling (MICROREV)

Heart Failure | Left Ventricular Dysfunction | Idiopathic Dilated Cardiomyopathy

Italy
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Healthy
Selene Guadalupe Huerta Olvera

Not yet recruiting

Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism

Centruroides Envenomation

Mexico
University of Oxford
Bill and Melinda Gates Foundation; University Hospitals Bristol and Weston...

Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Malaria,Falciparum

United Kingdom
UCB Biopharma SRL

Not yet recruiting

A Study to Assess the Safety and Pharmacokinetics of a Single Dose of UCB9741 in Healthy Caucasian and Japanese Participants

Healthy Participants
AstraZeneca

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of a Single Ascending Dose of AZD0292 In Healthy Participants

Healthy Participants Study

United States
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation Phase I Clinical Study to Assess the Safety, Pharmacokinetics, and Immunogenicity of HLX6018 in Healthy Subjects

IPF
Incyte Corporation

Recruiting

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

Healthy Participants

United Kingdom
AstraZeneca

Not yet recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Yonsei University

Recruiting

The Appropriate Remifentanil Dose for Optimal Insertion of Laryngeal Mask Airway in Adult Patients During Induction of General Anesthesia Using Remimazolam.

Adult, Laryngeal Masks, Remimazolam, Remifentanil

Korea, Republic of
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Advesya SAS

Not yet recruiting

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia (RESOLVE AML001)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

France, Sweden, Spain, Germany
Cairo University

Not yet recruiting

Cross Cultural Adaptation, Validity and Reliability Test of the Arabic Version of the Outpatient Physical Therapy Improvement in Movement Assessment Log (OPTIMAL)

Outpatients | Physical Performance
34 Lives, PBC
University of Miami; University of Wisconsin, Madison; MOUNT SINAI HOSPITAL; Indiana...

Recruiting

A Central Preservation and Assessment Service to Optimize Donor Kidney Allocation (OPTIMAL)

Organ Preservation

United States
SPA Società Prodotti Antibiotici S.p.A.
Pharmaceutical Development and Services

Recruiting

Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients

Osteoarthritis of Knee

Italy
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
Rousselot BVBA

Not yet recruiting

An Open Label, Dose-escalation Study, Assessing the Safety and Tolerability of a Collagen Peptide

Tolerance

United States
Hunazine Biotech S.L.

Recruiting

Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera

Cholera

Bangladesh
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
AstraZeneca
AstraZeneca K.K.

Recruiting

A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia (PURSUIT)

Dyslipidemia

Denmark, Hungary, Spain, United States, Japan, Czechia, Slovakia, Canada
Celgene

Recruiting

A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants

Healthy Participants

United States
St. Antonius Hospital

Recruiting

Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

Severe Aortic Valve Stenosis | Moderate Aortic Valve Stenosis

Netherlands
Kyungpook National University Chilgok Hospital

Recruiting

Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA

Thyroidectomy

Korea, Republic of
University of South Carolina

Recruiting

Determining the Optimal Amount of Structured Environments for Healthy Kids (DOSE)

Pediatric Obesity | Socioeconomic Factors | Health Status Disparities | Ethnic Groups

United States
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Incannex Healthcare Ltd

Recruiting

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA (REPOSA)

Obstructive Sleep Apnea

United States
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

Healthy Participants

United States, United Kingdom, Germany
G2GBio, Inc.

Recruiting

Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics From Single Dose of Intramuscular (IM) and Subcutaneous (SC) Donepezil (GB-5001) Injections Versus Donepezil Oral Tablet (Aricept®) in Healthy Male Volunteers

Alzheimer Disease

Korea, Republic of
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants

Healthy Participants

United States
AbbVie

Recruiting

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC) (LIVIGNO-2)

Hepatocellular Carcinoma

United States, Taiwan
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Regina Elena Cancer Institute
Azienda Policlinico Umberto I; San Giovanni Addolorata Hospital

Recruiting

Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers

Quality of Life | Larynx Cancer

Italy
Assiut University

Not yet recruiting

LDCT Chest In Assessment Of Apparently Healthy Smokers

Smoking
Radboud University Medical Center

Recruiting

Pragmatic Optimized Rifampicin Trial (PORT)

Tuberculosis, Pulmonary

Netherlands
Anagram Therapeutics, Inc.

Recruiting

Phase 1 Study to Assess Safety and Efficacy of ANG003

Exocrine Pancreatic Insufficiency

United States

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