Search clinical trials for: biosimilar,

Total 735 results

Cancer Institute and Hospital, Chinese Academy...

Recruiting

Multi-Centre, Observational Study on Safety of Bevacizumab Biosimilars in Clinical Practice Among Chinese Patients

Biosimilar

China
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit

Neovascular Age-related Macular Degeneration (nAMD)

United States
University Hospital, Grenoble

Recruiting

A 12-month Real Life Study of IBD Patients Switched From Adalimumab Originator Humira® to One of Its Biosimilar (Rhoneswitch)

IBD Patients, Originator Treatment, Biosimilar, Switch Back

France
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled Syringe

Neovascular Age-related Macular Degeneration (nAMD)

United States
Celltrion

Completed

Demonstrate the Equivalence of CT-P10 to MabThera With Respect to the Pharmacokinetic Profile in Patients With Rheumatoid Arthritis (Triad RA)

Rheumatoid Arthritis

Korea, Republic of
Celltrion

Terminated

Provide Initial Evidence of Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy to Support the Pivotal CT-P10 Therapeutic Equivalence Trial (Triad-DLBCL)

Diffuse Large B-Cell Lymphoma

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Switch From the Original Infliximab to Its Biosimilar in Daily Practice at Cochin Hospital (SIC)

Rheumatoid Arthritis | Uveitis | Crohn's Disease | Spondyloarthritis

France
Mylan Inc.
Mylan GmbH

Completed

Adalimumab PK Bioequivalence Study to EU and US Sourced Humira

Healthy Volunteers

Belgium
Hospital de Clinicas de Porto Alegre
Oswaldo Cruz Foundation; Rio Grande do Sul State Health Department - SES/RS

Completed

Efficacy Study of Two Formulations of Erythropoietin

Comparison of the Efficacy of Two Formulations of Epoetin in Patients Undergoing Hemodialysis
Mabwell (Shanghai) Bioscience Co., Ltd.

Completed

Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults (MW032)

Bone Tumor

China
Celltrion

Completed

An Extension Study to Demonstrate the Equivalence of Long-Term Efficacy and Safety of CT-P13 in Patients With Ankylosing Spondylitis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 1.1

Ankylosing Spondylitis

Korea, Republic of
Sun Yat-sen University

Recruiting

TACE Combined With Sintilimab Plus Bevacizumab Biosimilar in Hepatocellular Carcinoma (BCLC-C Stage ): a Prospective Single-arm Phase II Clinical Study (T-Double)

Hepatocellular Carcinoma

China
Celltrion

Completed

An Extension Study to Demonstrate Long-Term Efficacy and Safety of CT-P13 When Co-administered With Methotrexate in Patient With Rheumatoid Arthritis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 3.1

Rheumatoid Arthritis

Korea, Republic of
Pfizer

Completed

Infliximab Biosimilar for Intravenous Drip Infusion 100 mg "Pfizer" Drug Use Investigation (Psoriasis)

Psoriasis Vulgaris | Pustular Psoriasis | Psoriasis Arthropathica | Erythrodermic Psoriasis

Japan
Biocad

Completed

Study of Safety and Efficacy of BCD-020 Comparing to MabThera in Patients With Rheumatoid Arthritis (BIORA)

Rheumatoid Arthritis

India, Russian Federation, Belarus, Ukraine
Fresenius Kabi

Not yet recruiting

bIosimilar of aDalimumab, an European evAluation (IDEA)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis
Tianjin Medical University Cancer Institute and...

Recruiting

HAIC Combined With Sintilimab and Bevacizumab Biosimilar for Unresectable HCC

Hepatocellular Carcinoma

China
Sandoz
Novartis Pharmaceuticals

Completed

GP2013 in Japanese Patients With CD20 Positive Low Tumor Burden Indolent B-cell Non-Hodgkin's Lymphoma

Indolent B-cell Non-Hodgkin's Lymphoma

Japan
OnkoZentrum Zürich AG
University of Zurich; Palleos Healthcare GmbH

Completed

HER2-directed Biosimilar in Breast Cancer: Real World ePRO (OGIPRO)

HER2-positive Breast Cancer | Biosimilar | Patient Reported Outcome

Switzerland
Mylan Inc.
Mylan GmbH

Completed

MYL-1401A Efficacy and Safety Comparability Study to Humira®

Psoriasis | Arthritis, Psoriatic

Bulgaria, Estonia, Hungary, Poland, Russian Federation, Ukraine
Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Poland, United Kingdom
Fresenius Kabi SwissBioSim GmbH
PRA Health Sciences

Completed

Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Non-infectious Uveitis | Ankylosing Spondylitis | Pediatric Crohns Disease | Polyarticular Juvenile Idiopathic Arthritis | Pediatric Plaque Psoriasis

United States
Onze Lieve Vrouwe Gasthuis
Santeon

Unknown

"Efficacy and Safety of Infliximab-biosimilar (Inflectra) Compared to Infliximab-innovator (Remicade) in Patients With Inflammatory Bowel Disease in Remission: the SIMILAR Trial" (SIMILAR)

Crohn's Disease | Colitis, Ulcerative
Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB2 to Remicade® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Bulgaria, Lithuania
Fundació Institut de Recerca de l'Hospital de la...

Completed

Adalimumab Biosimilar in Clinical Practice

Psoriasis

Spain
Turgut Ardika PTY LTD

Recruiting

Comparative PK, Safety, Tolerability, Immunogenicity, and PD Profile Study of TUR03 and Soliris in Healthy Participants

Healthy

Australia
Pfizer

Active, not recruiting

Infliximab Biosimilar for Intravenous Drip Infusion 100 mg "Pfizer" Drug Use Investigation (Rheumatoid Arthritis)

Rheumatoid Arthritis

Japan
Dr. Reddy's Laboratories Limited
Parexel

Completed

Compare Efficacy, Safety, and Immunogenicity of Proposed Rituximab Biosimilar (DRL_RI) With MabThera® in LTB Follicular Lymphoma (FLINTER)

Follicular Lymphoma

United States
IVI Madrid
IVI Bilbao

Unknown

Biosimilar Versus Urinary Gonadotropins (BEMDON)

Infertility

Spain
Pfizer

Completed

A Study to Learn About the Study Medicine Called Infliximab (Genetical Recombination)[Infliximab Biosimilar 3] in People With Rheumatoid Arthritis, Ulcerative Colitis, Crohn's Disease, or Psoriasis

Arthritis, Rheumatoid | Psoriasis | Crohn Disease | Colitis, Ulcerative

Japan
Amgen
Parexel

Withdrawn

A Study of ABP 215 Versus Bevacizumab in Chinese Subjects With Advanced Non-Squamous Non-Small Cell Lung Cancer

Metastatic Non-small Cell Lung Cancer (NSCLC) | Non-squamous NSCLC
Shanghai Henlius Biotech

Completed

Phase I Study of HLX3 vs Adalimumab in Chinese Healthy Subjects

Immune System Disorder

China
Polpharma Biologics S.A.

Not yet recruiting

Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio® (UCESIVE)

Ulcerative Colitis
Pieter Dewint, MD PhD

Completed

Evaluation of the Safety and Effectiveness of Switching From Humira® to Imraldi® in Flanders (SafE-OrBi)

Inflammatory Bowel Diseases

Belgium
Julphar Gulf Pharmaceutical Industries
Profil Institut für Stoffwechselforschung GmbH

Completed

Pharmacokinetic (PK) Bioequivalence and Pharmacodynamics (PD) of Julphar Insulin 30/70 and Huminsulin® Profil III

Diabetes Mellitus

Germany
Julphar Gulf Pharmaceutical Industries
Parexel; Profil Institut für Stoffwechselforschung GmbH

Completed

Pharmacokinetic (PK) Bioequivalence and Pharmacodynamics of Julphar Insulin R and Huminsulin® Normal

Diabetes Mellitus

Germany
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Sub-cutaneous Infliximab in Inflammatory Rheumatic Disease (SIC2)

Rheumatoid Arthritis | Psoriatic Arthritis | Spondyloarthritis

France
Ospedale San Raffaele

Unknown

Infliximab Biosimilar in Takayasu's Arteritis (TAKASIM)

Takayasu Arteritis

Italy
Laboratorios Richmond S.A.C.I.F.
FP Clinical Pharma S.R.L.; Custom Biologics

Completed

A Clinical Study With Adalimumab Biosimilar

Pharmacokinetics | Safety Issues

Argentina
Fresenius Kabi SwissBioSim GmbH

Recruiting

Real World Use of Tocilizumab Biosimilar studY (RUBY)

Rheumatoid Arthritis

Germany
Laboratorios Liomont
Servicios Especializados en Ensayos Clínicos, S.C.

Recruiting

Safety of Effivia®, a Bevacizumab Biosimilar

Metastatic Colorectal Cancer | Metastatic Cervical Cancer | Non Squamous Non Small Cell Lung Cancer

Mexico
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
Novartis Pharmaceuticals

Completed

AScalate: Treat-to-target in Axial Spondyloarthritis (AScalate)

Axial Spondyloarthritis

Germany, France
Luye Pharma Group Ltd.

Active, not recruiting

Comparative Efficacy, Safety, PK, and Immunogenicity Study

Osteoporosis, Postmenopausal

Poland, United States, Czechia, Bulgaria, Japan
Biogen
Samsung Bioepis Co., Ltd.

Completed

Observational Study to Evaluate the Real-Life Effectiveness of Benepali Following Transition From Enbrel (BENEFIT)

Rheumatoid Arthritis | Axial Spondyloarthritis

Germany
Samsung Bioepis Co., Ltd.

Completed

A Study to Compare the Effect of SB3 and Herceptin® in Women With HER2 Positive Breast Cancer

HER2 Positive Early or Locally Advanced Breast Cancer

Czechia
Shandong University

Recruiting

Abraxane With Bevacizumab Biosimilar in Patients With Recurrent, Platinum-resistant Epithelial Ovarian Cancer

Objective Response Rate

China
Alteogen, Inc.
Cristália Produtos Químicos Farmacêuticos Ltda.

Completed

A Comparing Study Between ALT02(Trastuzumab Biosimilar) and Herceptin® in Healthy Subjects

Healthy
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

Breast Ductal Carcinoma In Situ

United States, Canada, Puerto Rico, Korea, Republic of
Amgen

Completed

A Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

United States, Canada, Poland, Estonia, Germany, Hungary, Latvia, Lithuania

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